NO941936L - Tetrahydropyranderivativer, fremgangsmåte for deres fremstilling og anvendelse - Google Patents

Tetrahydropyranderivativer, fremgangsmåte for deres fremstilling og anvendelse

Info

Publication number
NO941936L
NO941936L NO941936A NO941936A NO941936L NO 941936 L NO941936 L NO 941936L NO 941936 A NO941936 A NO 941936A NO 941936 A NO941936 A NO 941936A NO 941936 L NO941936 L NO 941936L
Authority
NO
Norway
Prior art keywords
preparation
hydroxy groups
antiinflammatory
tetrahydropyran derivatives
free
Prior art date
Application number
NO941936A
Other languages
English (en)
Other versions
NO308302B1 (no
NO941936D0 (no
Inventor
A R C Murty Bulusu
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310969A external-priority patent/GB9310969D0/en
Priority claimed from GB939310975A external-priority patent/GB9310975D0/en
Priority claimed from GB939312590A external-priority patent/GB9312590D0/en
Priority claimed from GB939313553A external-priority patent/GB9313553D0/en
Priority claimed from GB939319618A external-priority patent/GB9319618D0/en
Priority claimed from GB939319617A external-priority patent/GB9319617D0/en
Priority claimed from GB939326045A external-priority patent/GB9326045D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO941936D0 publication Critical patent/NO941936D0/no
Publication of NO941936L publication Critical patent/NO941936L/no
Publication of NO308302B1 publication Critical patent/NO308302B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Color Printing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO941936A 1993-05-27 1994-05-25 Tetrahydropyranderivativer, farmasøytisk preparat inneholdende slike derivater samt anvendelse derav NO308302B1 (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB939310969A GB9310969D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939310975A GB9310975D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939312590A GB9312590D0 (en) 1993-06-18 1993-06-18 Organic compounds
GB939313553A GB9313553D0 (en) 1993-07-01 1993-07-01 Organic compounds
GB939319618A GB9319618D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939319617A GB9319617D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939326045A GB9326045D0 (en) 1993-12-21 1993-12-21 Organic compounds

Publications (3)

Publication Number Publication Date
NO941936D0 NO941936D0 (no) 1994-05-25
NO941936L true NO941936L (no) 1994-11-28
NO308302B1 NO308302B1 (no) 2000-08-28

Family

ID=27562893

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941936A NO308302B1 (no) 1993-05-27 1994-05-25 Tetrahydropyranderivativer, farmasøytisk preparat inneholdende slike derivater samt anvendelse derav

Country Status (23)

Country Link
US (1) US5493019A (no)
EP (1) EP0626385B1 (no)
JP (1) JP3076724B2 (no)
CN (1) CN1048495C (no)
AT (1) ATE252105T1 (no)
AU (1) AU682499B2 (no)
CA (1) CA2124260C (no)
CY (1) CY2523B1 (no)
CZ (1) CZ286157B6 (no)
DE (1) DE69433234T2 (no)
DK (1) DK0626385T3 (no)
ES (1) ES2208651T3 (no)
FI (1) FI107159B (no)
HU (1) HU218919B (no)
IL (1) IL109775A (no)
MY (1) MY110603A (no)
NO (1) NO308302B1 (no)
NZ (1) NZ260596A (no)
PH (1) PH30420A (no)
PT (1) PT626385E (no)
RU (1) RU2130460C1 (no)
SI (1) SI0626385T1 (no)
SK (1) SK281541B6 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE299017T1 (de) 1994-10-26 2005-07-15 Novartis Pharma Gmbh Arzneimittel
WO1999019471A1 (en) 1997-10-16 1999-04-22 Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with nf-at3 function
DK1064942T3 (da) 1998-03-26 2004-11-01 Fujisawa Pharmaceutical Co Sustained release-fremstilling af et makrolid
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US6121257A (en) * 1999-03-31 2000-09-19 Abbott Laboratories Sulfamate containing macrocyclic immunomodulators
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
EP1531793A1 (en) 2002-07-23 2005-05-25 Novartis AG Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent
CA2552305A1 (en) * 2003-12-30 2005-07-14 Astellas Pharma Inc. Use of macrolides for treating or preventing airflow obstruction
GT200500282A (es) 2004-10-12 2006-05-04 Heteroatomos conteniendo compuestos triciclicos.
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
PL2454266T3 (pl) * 2009-07-15 2014-01-31 Cell Therapeutics Inc Sól cytrynianowa 9E-15-(2-pirolidyn-1-ylo-etoksy)-7,12,25-trioksa-19,21,24-triaza-tetracyklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaenu
CN107106588B (zh) 2014-10-28 2020-08-11 山口晃史 用于改善妊娠状态的药剂及其使用
JP7465806B2 (ja) 2018-08-10 2024-04-11 晃史 山口 母体と胎児との関係における液性免疫関連疾患の治療薬
CN113226331A (zh) 2018-12-18 2021-08-06 山口晃史 用于改善不孕不育症或妊娠状态的药物
US20220251108A1 (en) * 2019-01-23 2022-08-11 The Johns Hopkins University Non-immunosuppressive fk506 analogs and use thereof
JP7542876B2 (ja) * 2020-06-19 2024-09-02 モルジェンバイオ・カンパニー・リミテッド 神経突起成長及びシナプス形成活性を持つ新規プロリルｆｋ５０６誘導体及びその用途
US20230094227A1 (en) * 2020-12-24 2023-03-30 Seoul National University R&Db Foundation Novel fk506 derivative and composition comprising same for promoting hair growth

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078235A3 (de) * 1981-10-23 1983-06-29 Ciba-Geigy Ag Dihalogenierte Steroide
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
PH26083A (en) * 1987-11-09 1992-02-06 Sandoz Ltd 11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
EP0356399A3 (en) * 1988-08-26 1991-03-20 Sandoz Ag Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them
US4980466A (en) * 1988-10-12 1990-12-25 Merck & Co., Inc. Hydroxide mediated FK-506 rearrangement product
EP0385936A1 (de) * 1989-02-27 1990-09-05 Ciba-Geigy Ag Peptidlacton und derivate davon, Verfahren zu ihrer Herstellung und Mittel zur Ausführung des Verfahrens
US5057608A (en) * 1989-04-21 1991-10-15 Merck & Co., Inc. Immunoregulants, immunosuppressants, process to make ring expanded macrolide related to FK-506/FK-520
EP0594600A1 (en) * 1990-03-13 1994-05-04 FISONS plc Immunosuppressive macrocyclic compounds
CA2051872A1 (en) * 1990-09-24 1992-03-25 Kevin M. Byrne Directed biosynthesis process for prolyl-immunomycin
GB2249787A (en) * 1990-11-19 1992-05-20 Fujisawa Pharmaceutical Co Lactone compounds
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
JP3036923B2 (ja) * 1991-10-28 2000-04-24 理化学研究所 デプシペプチドａ、ｂその製造方法、並びに抗ウイルス剤及び抗菌剤
HUT66531A (en) * 1992-05-07 1994-12-28 Sandoz Ag Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them

Also Published As

Publication number Publication date
CZ286157B6 (cs) 2000-01-12
DE69433234T2 (de) 2004-08-05
EP0626385B1 (en) 2003-10-15
CZ129594A3 (en) 1995-01-18
DK0626385T3 (da) 2004-02-16
HK1011684A1 (en) 1999-07-16
HU9401582D0 (en) 1994-08-29
FI942444A0 (fi) 1994-05-25
EP0626385A1 (en) 1994-11-30
CA2124260A1 (en) 1994-11-28
JPH06340672A (ja) 1994-12-13
MY110603A (en) 1998-08-29
SK61194A3 (en) 1995-02-08
ATE252105T1 (de) 2003-11-15
RU2130460C1 (ru) 1999-05-20
SK281541B6 (sk) 2001-04-09
FI942444A7 (fi) 1994-11-28
ES2208651T3 (es) 2004-06-16
IL109775A0 (en) 1994-08-26
CN1048495C (zh) 2000-01-19
CY2523B1 (en) 2006-02-08
AU682499B2 (en) 1997-10-09
US5493019A (en) 1996-02-20
CA2124260C (en) 2007-04-17
NO308302B1 (no) 2000-08-28
AU6331794A (en) 1994-12-01
NZ260596A (en) 1995-10-26
JP3076724B2 (ja) 2000-08-14
HUT71396A (en) 1995-11-28
PT626385E (pt) 2004-03-31
IL109775A (en) 1999-07-14
NO941936D0 (no) 1994-05-25
FI107159B (fi) 2001-06-15
SI0626385T1 (en) 2004-02-29
DE69433234D1 (de) 2003-11-20
HU218919B (hu) 2000-12-28
CN1099756A (zh) 1995-03-08
PH30420A (en) 1997-05-09

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Legal Events

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