NO943371L - Fremgangsmåte for fremstilling av taxanderivater - Google Patents

Fremgangsmåte for fremstilling av taxanderivater

Info

Publication number
NO943371L
NO943371L NO943371A NO943371A NO943371L NO 943371 L NO943371 L NO 943371L NO 943371 A NO943371 A NO 943371A NO 943371 A NO943371 A NO 943371A NO 943371 L NO943371 L NO 943371L
Authority
NO
Norway
Prior art keywords
residue
preparation
general formula
taxane derivatives
acetyl
Prior art date
Application number
NO943371A
Other languages
English (en)
Other versions
NO943371D0 (no
Inventor
Dominique Deprez
Jean-Pierre Pulicani
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO943371L publication Critical patent/NO943371L/no
Publication of NO943371D0 publication Critical patent/NO943371D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
    • C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
    • C25B11/042—Electrodes formed of a single material
    • C25B11/043—Carbon, e.g. diamond or graphene
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
    • C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
    • C25B11/042—Electrodes formed of a single material
    • C25B11/046—Alloys
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/05—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/07—Oxygen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/09—Nitrogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Fremgangsmåte for fremstilling av et taxanderivat med den generelle formel:. der. R betyr et hydrogenatom eller en acetylrest,. Rj betyr en benzylrest eller en rest R-O-CO-, der. Rbetyr en alkyl-, alkenyl-, alkynyl-, cykloalkyl-, cyklo-alkenyl—, bicykloalkyl-, fenyl- eller en nitrogenheterocykelrest og. Ar betyr en arylrest,. der man gjennomfører en elektrolytisk reduksjon av et produkt med den generelle formel:. der. Ar og Ri er som angitt ovenfor, R' betyr en acetylrest eller en 2,2,2-trikloretoksykarbonylrest.Produktene med formel (I) har antitumorale egenskaper.
NO943371A 1992-03-13 1994-09-12 Fremgangsmåte for fremstilling av taxanderivater NO943371D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9203000A FR2688518B1 (fr) 1992-03-13 1992-03-13 Procede de preparation de derives du taxane.
PCT/FR1993/000243 WO1993018210A1 (fr) 1992-03-13 1993-03-11 Procede de preparation de derives du taxane

Publications (2)

Publication Number Publication Date
NO943371L true NO943371L (no) 1994-09-12
NO943371D0 NO943371D0 (no) 1994-09-12

Family

ID=9427641

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943371A NO943371D0 (no) 1992-03-13 1994-09-12 Fremgangsmåte for fremstilling av taxanderivater

Country Status (21)

Country Link
EP (1) EP0630428B1 (no)
JP (1) JPH07504461A (no)
KR (1) KR950700439A (no)
AT (1) ATE130053T1 (no)
AU (1) AU3756393A (no)
CA (1) CA2117552A1 (no)
CZ (1) CZ218694A3 (no)
DE (1) DE69300766T2 (no)
DK (1) DK0630428T3 (no)
ES (1) ES2079982T3 (no)
FI (1) FI944190A0 (no)
FR (1) FR2688518B1 (no)
GR (1) GR3018036T3 (no)
HU (1) HUT68282A (no)
MX (1) MX9301345A (no)
NO (1) NO943371D0 (no)
RU (1) RU94041682A (no)
SK (1) SK108494A3 (no)
TW (1) TW235961B (no)
WO (1) WO1993018210A1 (no)
ZA (1) ZA931800B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
DK1227093T3 (da) * 1993-03-22 2005-08-29 Univ Florida State Beta-lactamer, der kan anvendes til fremstilling af taxaner med en furyl- eller thienylsubstitueret sidekæde
US5760251A (en) * 1995-08-11 1998-06-02 Sepracor, Inc. Taxol process and compounds
US6103698A (en) 1997-03-13 2000-08-15 Basf Aktiengesellschaft Dolastatin-15 derivatives in combination with taxanes
ES2649817T3 (es) 2002-04-05 2018-01-15 Roche Innovation Center Copenhagen A/S Compuestos oligom¿¿ricos para la modulaci¿®n de la expresi¿®n de HIF-1¿Á
US7713738B2 (en) 2003-02-10 2010-05-11 Enzon Pharmaceuticals, Inc. Oligomeric compounds for the modulation of survivin expression
ES2344566T3 (es) 2003-12-23 2010-08-31 Santaris Pharma A/S Compuestos oligomericos para la modulacion de bcl-2.
US9447138B2 (en) 2004-11-09 2016-09-20 Roche Innovation Center Copenhagen A/S Potent LNA oligonucleotides for the inhibition of HIF-1a expression
EP1824975B9 (en) 2004-11-09 2011-04-20 Santaris Pharma A/S Lna oligonucleotides and the treatment of cancer
BRPI0515726A8 (pt) 2004-11-09 2017-09-12 Santaris Pharma As Oligonucleotídeos de lna potentes para a inibição de expressão de hif-1a
US20260137674A1 (en) 2024-10-23 2026-05-21 Incyte Corporation Combination therapy using a kras g12d inhibitor, and a nucleoside analog, and/or a microtubule inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60187689A (ja) * 1984-03-06 1985-09-25 Otsuka Chem Co Ltd ３−エキソメチレンセフアム誘導体の製造法
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2664894A1 (fr) * 1990-07-19 1992-01-24 Rhone Poulenc Sante Nouveaux derives de streptogramines et leur preparation.

Also Published As

Publication number Publication date
FR2688518B1 (fr) 1994-05-06
CA2117552A1 (fr) 1993-09-16
RU94041682A (ru) 1996-07-20
HUT68282A (en) 1995-04-03
EP0630428B1 (fr) 1995-11-08
ZA931800B (en) 1993-09-30
KR950700439A (ko) 1995-01-16
SK108494A3 (en) 1995-02-08
FI944190A7 (fi) 1994-09-12
DK0630428T3 (da) 1995-12-27
DE69300766T2 (de) 1996-04-18
DE69300766D1 (de) 1995-12-14
MX9301345A (es) 1993-09-01
FR2688518A1 (fr) 1993-09-17
ATE130053T1 (de) 1995-11-15
ES2079982T3 (es) 1996-01-16
TW235961B (no) 1994-12-11
HU9402614D0 (en) 1994-11-28
EP0630428A1 (fr) 1994-12-28
NO943371D0 (no) 1994-09-12
JPH07504461A (ja) 1995-05-18
CZ218694A3 (en) 1995-02-15
WO1993018210A1 (fr) 1993-09-16
FI944190A0 (fi) 1994-09-12
GR3018036T3 (en) 1996-02-29
AU3756393A (en) 1993-10-05

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