NO950936L - 5-vinyl- og 5-etinylchinolon- og naftyridonkarboksylsyrer - Google Patents

5-vinyl- og 5-etinylchinolon- og naftyridonkarboksylsyrer

Info

Publication number
NO950936L
NO950936L NO950936A NO950936A NO950936L NO 950936 L NO950936 L NO 950936L NO 950936 A NO950936 A NO 950936A NO 950936 A NO950936 A NO 950936A NO 950936 L NO950936 L NO 950936L
Authority
NO
Norway
Prior art keywords
halogen
vinyl
carboxylic acids
alkyl
atoms
Prior art date
Application number
NO950936A
Other languages
English (en)
Other versions
NO950936D0 (no
Inventor
Thomas Himmler
Uwe Petersen
Klaus-Dieter Bremm
Rainer Endermann
Michael Stegemann
Heinz-Georg Wetzstein
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO950936D0 publication Critical patent/NO950936D0/no
Publication of NO950936L publication Critical patent/NO950936L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/762—Organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/771—Organic compounds containing hetero rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Quinoline Compounds (AREA)

Abstract

Det blir beskrevet nye 5-vlnyl- og 5-etinyl-chlnolon- og -naftyridonkarboksylsyrer med formel I hvor R1 står for rettkjedet eller forgrenet C^-C^alkyl, som eventuelt er substituert med hydroksy, halogen, C^- C3-alkoksy, for C3-Cfc-cykloalkyl som eventuelt er substituert med halogen eller Cj-CQ-alkyl, 02-04- alkenyl, foruten for Ci-C3-alkoksy, amino, monoalky- lamino med l til 3 C-atomer, dialkylamino med 2 til 6 C-atomer eller for fenyl som eventuelt er en til tre ganger substituert med halogen, R2 står for hydrogen, alkyl med l til 4 karbonatomer eller (5-metyl-2-okso-l,3-dloksol-4-yl)-metyl, X står for en gruppering CH, C-halogen, COCH3, COCHF2, C-CH3 eller N Z står for -C-CH-R3 eller -C=C-R5, R4 Y står for en heterosyklus. Det blir også beskrevet en fremgangsmåte for frem- stilling av disse forbindelsene samt antlbakterielle midler og ffirtllsetnlngsstoffer Inneholdende dem.
NO950936A 1994-03-11 1995-03-10 5-vinyl- og 5-etinylchinolon- og naftyridonkarboksylsyrer NO950936L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4408212A DE4408212A1 (de) 1994-03-11 1994-03-11 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren

Publications (2)

Publication Number Publication Date
NO950936D0 NO950936D0 (no) 1995-03-10
NO950936L true NO950936L (no) 1995-09-12

Family

ID=6512492

Family Applications (1)

Application Number Title Priority Date Filing Date
NO950936A NO950936L (no) 1994-03-11 1995-03-10 5-vinyl- og 5-etinylchinolon- og naftyridonkarboksylsyrer

Country Status (29)

Country Link
US (2) US5578604A (no)
EP (1) EP0671391A1 (no)
JP (1) JPH07285941A (no)
KR (1) KR950032177A (no)
CN (1) CN1111629A (no)
AU (1) AU689189B2 (no)
BG (1) BG62001B1 (no)
CA (1) CA2144231A1 (no)
CO (1) CO4340737A1 (no)
CZ (1) CZ63895A3 (no)
DE (1) DE4408212A1 (no)
DZ (1) DZ1862A1 (no)
EE (1) EE9500020A (no)
FI (1) FI951101L (no)
HR (1) HRP950077A2 (no)
HU (1) HUT72071A (no)
IL (1) IL112936A0 (no)
LV (1) LV11469B (no)
MA (1) MA23475A1 (no)
NO (1) NO950936L (no)
NZ (1) NZ270657A (no)
PE (1) PE33895A1 (no)
PL (1) PL307583A1 (no)
RU (1) RU95103433A (no)
SK (1) SK31695A3 (no)
SV (1) SV1995000012A (no)
TN (1) TNSN95017A1 (no)
YU (1) YU15895A (no)
ZA (1) ZA952008B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
DE19652219A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(1-Aminomethyl-2-oxa-7-azabicyclo[3.3.0]oct-7-yl)-chinolon- und naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
US6984499B2 (en) * 1997-10-02 2006-01-10 Idexx Laboratories, Inc. Method and apparatus for concurrently detecting pathogenic organisms and antimicrobial susceptibility
MXPA02005884A (es) * 1999-12-14 2002-10-23 Neurosearch As Heteroaril-diazabicicloalcanos novedosos.
US7175988B2 (en) 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
ATE289310T1 (de) * 2001-06-01 2005-03-15 Neurosearch As Heteroaryl-diazabicycloalkanderivaten als cns- modulatoren
DE60233728D1 (de) * 2001-06-06 2009-10-29 Neurosearch As Kationenleitende gaba-a-rezeptoren und deren verwendung
US7393934B2 (en) 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
PL1666477T3 (pl) 2003-09-10 2013-11-29 Kyorin Seiyaku Kk Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego
WO2005105841A2 (en) 2004-03-12 2005-11-10 Human Genome Sciences, Inc. Human g-protein chemokine receptor (ccr5) hdgnr10
JP5322927B2 (ja) 2007-05-24 2013-10-23 杏林製薬株式会社 １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
CN103724262B (zh) * 2013-12-10 2016-05-18 广东省第二人民医院 一种氟喹诺酮银化合物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
NO885426L (no) * 1987-12-11 1989-06-12 Dainippon Pharmaceutical Co Kinolinderivater, samt fremgangsmaate ved fremstilling derav.
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
US5140033A (en) * 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
US5252734A (en) * 1989-04-03 1993-10-12 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
EP0593766B1 (en) * 1991-05-28 2000-09-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative

Also Published As

Publication number Publication date
KR950032177A (ko) 1995-12-20
RU95103433A (ru) 1997-02-10
CN1111629A (zh) 1995-11-15
FI951101A7 (fi) 1995-09-12
JPH07285941A (ja) 1995-10-31
YU15895A (sh) 1998-05-15
FI951101L (fi) 1995-09-12
HU9500728D0 (en) 1995-04-28
US5659038A (en) 1997-08-19
EP0671391A1 (de) 1995-09-13
EE9500020A (et) 1995-12-15
IL112936A0 (en) 1995-06-29
CO4340737A1 (es) 1996-07-30
HRP950077A2 (en) 1997-08-31
AU1364995A (en) 1995-09-21
MA23475A1 (fr) 1995-10-01
PL307583A1 (en) 1995-09-18
NZ270657A (en) 1997-01-29
CA2144231A1 (en) 1995-09-12
FI951101A0 (fi) 1995-03-09
CZ63895A3 (en) 1995-11-15
ZA952008B (en) 1995-12-11
US5578604A (en) 1996-11-26
LV11469A (lv) 1996-08-20
TNSN95017A1 (fr) 1996-02-06
SK31695A3 (en) 1995-09-13
BG62001B1 (bg) 1998-12-30
DE4408212A1 (de) 1995-09-14
LV11469B (en) 1996-12-20
SV1995000012A (es) 1995-11-06
HUT72071A (en) 1996-03-28
PE33895A1 (es) 1995-12-15
NO950936D0 (no) 1995-03-10
BG99490A (en) 1996-01-31
DZ1862A1 (fr) 2002-02-17
AU689189B2 (en) 1998-03-26

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