NO954458L - Adhesjonsreseptorantagonister - Google Patents

Adhesjonsreseptorantagonister

Info

Publication number
NO954458L
NO954458L NO954458A NO954458A NO954458L NO 954458 L NO954458 L NO 954458L NO 954458 A NO954458 A NO 954458A NO 954458 A NO954458 A NO 954458A NO 954458 L NO954458 L NO 954458L
Authority
NO
Norway
Prior art keywords
adhesjonsreseptorantagonister
Prior art date
Application number
NO954458A
Other languages
English (en)
Other versions
NO954458D0 (no
NO306113B1 (no
Inventor
Joachim Gante
Horst Juraszyk
Peter Raddatz
Hanns Wurziger
Sabine Bernotat-Danielowski
Guido Melzer
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO954458D0 publication Critical patent/NO954458D0/no
Publication of NO954458L publication Critical patent/NO954458L/no
Publication of NO306113B1 publication Critical patent/NO306113B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO954458A 1994-11-08 1995-11-07 Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler NO306113B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4439846A DE4439846A1 (de) 1994-11-08 1994-11-08 Adhäsionsrezeptor-Antagonisten

Publications (3)

Publication Number Publication Date
NO954458D0 NO954458D0 (no) 1995-11-07
NO954458L true NO954458L (no) 1996-05-09
NO306113B1 NO306113B1 (no) 1999-09-20

Family

ID=6532768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954458A NO306113B1 (no) 1994-11-08 1995-11-07 Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler

Country Status (22)

Country Link
US (1) US5776937A (no)
EP (1) EP0711770A1 (no)
JP (1) JPH08208629A (no)
KR (1) KR100384978B1 (no)
CN (1) CN1069640C (no)
AR (1) AR002245A1 (no)
AU (1) AU704184B2 (no)
BR (1) BR9505109A (no)
CA (1) CA2162223A1 (no)
CO (1) CO4520229A1 (no)
CZ (1) CZ291049B6 (no)
DE (1) DE4439846A1 (no)
FI (1) FI955351L (no)
HU (1) HU217085B (no)
NO (1) NO306113B1 (no)
PL (1) PL183595B1 (no)
RU (1) RU2155762C2 (no)
SK (1) SK281815B6 (no)
TR (1) TR199501389A2 (no)
TW (1) TW316903B (no)
UA (1) UA41928C2 (no)
ZA (1) ZA959434B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
ATE170179T1 (de) * 1994-11-02 1998-09-15 Merck Patent Gmbh Adhäsionsrezeptor-antagonisten
US6046331A (en) * 1998-12-17 2000-04-04 Synaptic Pharmaceutical Corporation Imidazolones and their use in treating benign prostatic hyperplasia and other disorders
CN1398189A (zh) 1998-12-23 2003-02-19 G.D.西尔公司 用于治疗肿瘤形成的放疗与cox-2抑制剂的联合治疗
EP1147422A1 (en) 1999-01-27 2001-10-24 Pharmacia & Upjohn Company Assays for modulators of "elongation factor p" activity
MXPA04007067A (es) * 2002-01-22 2004-11-01 Upjohn Co Dispositivos medicos resistentes a infecciones.
WO2004032856A2 (en) * 2002-10-07 2004-04-22 Smithkline Beecham Corporation Compounds
TWI341312B (en) * 2002-12-24 2011-05-01 Sankyo Co Optical active dihydropyridine derivatives
CN102796091A (zh) * 2011-05-24 2012-11-28 北大方正集团有限公司 取代的噁唑烷酮化合物及其制备方法和应用
IN2015DN00961A (no) * 2012-10-29 2015-06-12 Hoffmann La Roche
CN104230915B (zh) * 2014-08-29 2016-08-17 南京大学 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途
WO2018236745A1 (en) 2017-06-20 2018-12-27 Carnot, Llc COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF CARDIAC METABOLISM
EP4497474A3 (en) 2018-10-17 2025-04-23 Imbria Pharmaceuticals, Inc. Methods of treating rheumatic diseases using trimetazidine-based compounds
EP3976101A4 (en) 2019-05-31 2023-06-21 Imbria Pharmaceuticals, Inc. FIBROSIS TREATMENT METHODS USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3723797A1 (de) * 1987-07-18 1989-01-26 Merck Patent Gmbh Oxazolidinone
US5053393A (en) * 1988-07-20 1991-10-01 Monsanto Company Novel platelet-aggregation inhibitor
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5084466A (en) * 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
DE4005371A1 (de) * 1990-02-21 1991-08-22 Merck Patent Gmbh Oxazolidinone
DE4017211A1 (de) * 1990-05-29 1991-12-05 Merck Patent Gmbh Oxazolidinone
DE4405633A1 (de) * 1993-05-01 1994-11-03 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten
ATE181735T1 (de) * 1993-05-01 1999-07-15 Merck Patent Gmbh Substituierte 1-phenyl-oxazolidin-2-on derivate, deren herstellung und deren verwendung als adhäsionsrezeptor-antagonisten
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III

Also Published As

Publication number Publication date
AR002245A1 (es) 1998-03-11
TR199501389A2 (tr) 1996-07-21
FI955351A0 (fi) 1995-11-07
TW316903B (no) 1997-10-01
BR9505109A (pt) 1997-09-09
CA2162223A1 (en) 1996-05-09
KR960017663A (ko) 1996-06-17
HUT76052A (en) 1997-06-30
FI955351A7 (fi) 1996-05-09
ZA959434B (en) 1996-05-15
SK136895A3 (en) 1996-06-05
AU704184B2 (en) 1999-04-15
RU2155762C2 (ru) 2000-09-10
SK281815B6 (sk) 2001-08-06
US5776937A (en) 1998-07-07
CO4520229A1 (es) 1997-10-15
CN1132201A (zh) 1996-10-02
CZ288895A3 (en) 1996-06-12
UA41928C2 (uk) 2001-10-15
CN1069640C (zh) 2001-08-15
CZ291049B6 (cs) 2002-12-11
EP0711770A1 (de) 1996-05-15
PL311257A1 (en) 1996-05-13
DE4439846A1 (de) 1996-05-09
NO954458D0 (no) 1995-11-07
AU3661895A (en) 1996-05-23
HU9503191D0 (en) 1996-01-29
HU217085B (hu) 1999-11-29
KR100384978B1 (ko) 2003-09-02
NO306113B1 (no) 1999-09-20
JPH08208629A (ja) 1996-08-13
FI955351L (fi) 1996-05-09
PL183595B1 (pl) 2002-06-28

Similar Documents

Publication Publication Date Title
DE59508357D1 (de) Stereomikroscop
ATA166795A (de) Bis-resorcinyltriazine
ATA147195A (de) Alkoxyphenyl-substituierte bisbenzoylphosphinoxide
ATA163695A (de) 2-hydroxyphenyltriazine
DE69432190D1 (de) Papamycinderivate
NO954458D0 (no) Adhesjonsreseptorantagonister
DE59501347D1 (de) Hydroxyphenylharnstoffe
DE59506964D1 (de) Polyglycerinpolyricinoleate
ATA108995A (de) Differenzdruckakkumulator
DE59510691D1 (de) Dipolspeiseanordnung
DE59503633D1 (de) Zyklonsichter
DE59508868D1 (de) Dihydrofarnesal
DE69415306D1 (de) Ablenkjoch
ATA11894A (de) Stauförderbahn
DE59507451D1 (de) Cyanoisoxazole
ATE197372T1 (de) Vorteig
BR9405342A (pt) Auto-elevador
BR7402342U (pt) Hidro-potenciômetro
BR9401264A (pt) Prevgás
BR7400053U (pt) T-compacto
BR9402584A (pt) Chavecheque
ITLU940014V0 (it) Bloccomuro
BR9401864A (pt) Pescoço-giratório
BR9401966A (pt) Intervalômetro-foto ARJ-07
BR9400154A (pt) Telaprotege

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees