NO960649D0 - Vasokonstriktive dehydrobenzopyranderivater - Google Patents

Vasokonstriktive dehydrobenzopyranderivater

Info

Publication number: NO960649D0
Authority: NO; Norway
Prior art keywords: 6alkyl; hydrogen; designate; 6alkyloxy; halo
Prior art date: 1993-08-19

Application number

NO960649A

Other languages

English (en)

Other versions

NO315235B1 (no

NO960649L (no

Inventor

Guy Rosalia Eugene Van Lommen

Piet Tom Bert Paul Wigerinck

Marcel Frans Leopold De Bruyn

Wim Gaston Verschueren

Marc Francis Josephin Schroven

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-08-19

Filing date

1996-02-19

Publication date

1996-02-19

1996-02-19 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1996-02-19 Publication of NO960649D0 publication Critical patent/NO960649D0/no

1996-02-19 Publication of NO960649L publication Critical patent/NO960649L/no

2003-08-04 Publication of NO315235B1 publication Critical patent/NO315235B1/no

Links

230000003639 vasoconstrictive effect Effects 0.000 title 1
239000001257 hydrogen Substances 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 6
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
-1 C1-6alkyloxy Chemical group 0.000 abstract 5
125000001475 halogen functional group Chemical group 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000005017 substituted alkenyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Polymerisation Methods In General (AREA)
Cephalosporin Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Dental Preparations (AREA)

NO19960649A 1993-08-19 1996-02-19 Vasokonstriktive dihydrobenzopyranderivater, sammensetning inneholdende detsamme og anvendelse derav NO315235B1 (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP93202441		1993-08-19
EP93202442		1993-08-19
EP93202443		1993-08-19
PCT/EP1994/002703 WO1995005383A1 (en)	1993-08-19	1994-08-12	Vasocontrictive dihydrobenzopyran derivatives

Publications (3)

Publication Number	Publication Date
NO960649D0 true NO960649D0 (no)	1996-02-19
NO960649L NO960649L (no)	1996-02-19
NO315235B1 NO315235B1 (no)	2003-08-04

Family

ID=27235325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19960649A NO315235B1 (no)	1993-08-19	1996-02-19	Vasokonstriktive dihydrobenzopyranderivater, sammensetning inneholdende detsamme og anvendelse derav

Country Status (25)

Country	Link
US (2)	US5824682A (no)
EP (1)	EP0714396B1 (no)
JP (1)	JP3044065B2 (no)
KR (1)	KR100330696B1 (no)
CN (1)	CN1052006C (no)
AT (1)	ATE256130T1 (no)
AU (1)	AU677428B2 (no)
BR (1)	BR9407317A (no)
CA (1)	CA2168021C (no)
CZ (1)	CZ287771B6 (no)
DE (1)	DE69433401T2 (no)
ES (1)	ES2212797T3 (no)
FI (1)	FI120791B (no)
HU (1)	HU226525B1 (no)
IL (1)	IL110687A (no)
MY (1)	MY134487A (no)
NO (1)	NO315235B1 (no)
NZ (1)	NZ271995A (no)
PL (1)	PL181385B1 (no)
RO (1)	RO116900B1 (no)
RU (1)	RU2129556C1 (no)
SK (1)	SK282402B6 (no)
TW (1)	TW269684B (no)
WO (1)	WO1995005383A1 (no)
ZA (1)	ZA946269B (no)

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ES2212797T3 (es) *	1993-08-19	2004-08-01	Janssen Pharmaceutica N.V.	Derivados de dihidrobenzopirano vasoconstrictores.
ATE210657T1 (de) *	1994-10-14	2001-12-15	Merck Patent Gmbh	Zns wirksames (r)-(-)-2-(5-(4-fluorophenyl)-3- pyridylmethylaminomethyl)chroman
US5541199A (en) *	1995-06-02	1996-07-30	American Home Products Corporation	Chroman-2-ylmethylamino derivatives
US5663194A (en) *	1995-07-25	1997-09-02	Mewshaw; Richard E.	Chroman-2-ylmethylamino derivatives
US5670667A (en) *	1995-07-25	1997-09-23	American Home Products Corporation	Chroman-2-ylmethylamino derivatives
US5684039A (en) *	1995-07-25	1997-11-04	American Home Products Corporation	Chroman-2-ylmethylamino derivatives
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
US6133277A (en) *	1997-12-05	2000-10-17	Janssen Pharmaceutica N.V.	(Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
SK286159B6 (sk)	1999-06-02	2008-04-07	Janssen Pharmaceutica N. V.	Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
EE04780B1 (et)	1999-06-02	2007-02-15	Janssen Pharmaceutica N.V.	Aminoalküül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod
DE19948480A1 (de)	1999-10-08	2001-04-12	Bsh Bosch Siemens Hausgeraete	Wärmetauscher, wie Verdampfer, Verflüssiger oder dergleichen
JO2178B1 (en) *	1999-10-19	2003-04-23	اف . هوفمان لاروش ايه جي	Treatment of emphysema using rar selective retinoid antagonists
JO2654B1 (en)	2000-09-04	2012-06-17	شركة جانسين فارماسوتيكا ان. في	Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en)	2000-11-21	2007-06-17	شركة جانسين فارماسوتيكا ان. في	Second-phenyl carboxy amides are useful as lipid-lowering agents
DE10120619A1 (de) *	2001-04-26	2002-10-31	Merck Patent Gmbh	2-(5-(4-Fluorphenyl)-3-pyridylmethylaminomethyl-chroman
ES2229138T3 (es)	2001-04-26	2005-04-16	Wyeth	Derivados antidepresivos azaheterociclilmetilicos de (1,4)- benzodiaxanos condensados con oxaheterociclos.
US6706736B2 (en)	2001-04-26	2004-03-16	Wyeth	Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans
US6555560B2 (en)	2001-04-30	2003-04-29	Wyeth	Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6906206B2 (en) *	2001-04-30	2005-06-14	Wyeth	Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
PL208787B1 (pl) *	2001-09-19	2011-06-30	Merck Patent Gmbh	(2R, 4R/S)-2-({[5-(4-fluorofenylo)-pirydyn-3ylmetylo)]-amino}-metylo)-chroman-4-ol i (2R, 4R)-2-({[5-(4-fluorofenylo)-pirydyn-3ylmetylo)]-amino}-metylo)-chroman-4-ol, sposoby ich otrzymywania i zastosowanie do wytwarzania preparatów medycznych oraz zawierająca je kompozycja farmaceutyczna
JP2005505586A (ja) *	2001-10-04	2005-02-24	ワイス	５−ヒドロキシトリプタミン−６リガンドとしてのクロマン誘導体
WO2003029239A1 (en)	2001-10-04	2003-04-10	Wyeth	Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands
DE60325956D1 (de) *	2002-04-10	2009-03-12	Dongbu Hitek Co Ltd	Benzopyranderivate, die mit sekundären aminen einschliesslich tetrazol substituiert sind, verfahren etzungen, die diese enthalten
CA2581454A1 (en) *	2004-09-23	2006-03-30	Reddy Us Therapeutics, Inc.	Novel pyrimidine compounds, process for their preparation and compositions containing them
WO2006116165A1 (en) *	2005-04-22	2006-11-02	Wyeth	Chromane and chromene derivatives and uses thereof
AR059898A1 (es)	2006-03-15	2008-05-07	Janssen Pharmaceutica Nv	Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200815388A (en) *	2006-04-18	2008-04-01	Wyeth Corp	Chromane and chromene derivatives and uses thereof
CL2007003043A1 (es) *	2006-10-24	2008-05-30	Wyeth Corp	Compuestos derivados de cromano; composicion farmaceutica que los comprende; y uso para el tratamiento de un trastorno psicotico, bipolar, depresivo y ansiedad entre otros.
TW200845978A (en) *	2007-03-07	2008-12-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en)	2007-03-07	2009-01-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
SI2203439T1 (sl)	2007-09-14	2011-05-31	Ortho Mcneil Janssen Pharm	1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni
CN101801930B (zh) *	2007-09-14	2013-01-30	奥梅-杨森制药有限公司	1,3-二取代的-4-苯基-1h-吡啶-2-酮
PL2200985T3 (pl)	2007-09-14	2011-12-30	Ortho Mcneil Janssen Pharmaceuticals Inc	1,3-Dipodstawione-4-(arylo-X-fenylo)-1H-pirydyn-2-ony
CN101861316B (zh) *	2007-11-14	2013-08-21	奥梅-杨森制药有限公司	咪唑并[1,2-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
EP2344470B1 (en)	2008-09-02	2013-11-06	Janssen Pharmaceuticals, Inc.	3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
WO2010043396A1 (en)	2008-10-16	2010-04-22	Ortho-Mcneil-Janssen Pharmaceuticals, Inc.	Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
JP5690277B2 (ja)	2008-11-28	2015-03-25	ジャンセンファーマシューティカルズ，インコーポレイテッド．	代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体
CN102439008B (zh)	2009-05-12	2015-04-29	杨森制药有限公司	1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
MY153913A (en)	2009-05-12	2015-04-15	Janssen Pharmaceuticals Inc	7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
BRPI1010831A2 (pt)	2009-05-12	2016-04-05	Addex Pharmaceuticals Sa	derivados de 1,2,4-triazolo[4,3-a]piridina e seu como moduladores alostéricos positivos de receptores de mglur2
AU2011328203B2 (en)	2010-11-08	2015-03-19	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
US9271967B2 (en)	2010-11-08	2016-03-01	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
ES2536433T3 (es)	2010-11-08	2015-05-25	Janssen Pharmaceuticals, Inc.	Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
JO3368B1 (ar)	2013-06-04	2019-03-13	Janssen Pharmaceutica Nv	مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
ME03518B (me)	2014-01-21	2020-04-20	Janssen Pharmaceutica Nv	Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
MX386697B (es)	2014-01-21	2025-03-19	Janssen Pharmaceutica Nv	Combinaciones que comprenden agonistas ortostericos o moduladores alostericos positivos del receptor glutamatergico metabotropico de subtipo 2 y su uso

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US4405622A (en) *	1980-10-16	1983-09-20	Syntex (U.S.A.) Inc.	[1-(1,4-Benzodioxan-2-yl)-4-(4-aminopyrimidin-2-yl]piperazines useful as anti-depressants
CA1337429C (en) *	1983-12-05	1995-10-24	Guy Rosalia Eugene Van Lommen	Derivatives of 2,2'-iminobisethanol
FR2593504B1 (fr) *	1986-01-30	1988-12-09	Ile De France	Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
DE3901814A1 (de) *	1988-07-28	1990-02-01	Bayer Ag	Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
SI9300097B (en) *	1992-02-27	2001-12-31	Janssen Pharmaceutica Nv	(benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
ES2212797T3 (es) *	1993-08-19	2004-08-01	Janssen Pharmaceutica N.V.	Derivados de dihidrobenzopirano vasoconstrictores.

1994
- 1994-08-12 ES ES94926191T patent/ES2212797T3/es not_active Expired - Lifetime
- 1994-08-12 HU HU9600373A patent/HU226525B1/hu unknown
- 1994-08-12 CA CA002168021A patent/CA2168021C/en not_active Expired - Lifetime
- 1994-08-12 BR BR9407317A patent/BR9407317A/pt not_active Application Discontinuation
- 1994-08-12 SK SK195-96A patent/SK282402B6/sk not_active IP Right Cessation
- 1994-08-12 US US08/586,760 patent/US5824682A/en not_active Expired - Lifetime
- 1994-08-12 EP EP94926191A patent/EP0714396B1/en not_active Expired - Lifetime
- 1994-08-12 RO RO96-00284A patent/RO116900B1/ro unknown
- 1994-08-12 CN CN94193152A patent/CN1052006C/zh not_active Expired - Lifetime
- 1994-08-12 CZ CZ1996374A patent/CZ287771B6/cs not_active IP Right Cessation
- 1994-08-12 WO PCT/EP1994/002703 patent/WO1995005383A1/en not_active Ceased
- 1994-08-12 PL PL94313082A patent/PL181385B1/pl unknown
- 1994-08-12 KR KR1019960700632A patent/KR100330696B1/ko not_active Expired - Lifetime
- 1994-08-12 AT AT94926191T patent/ATE256130T1/de not_active IP Right Cessation
- 1994-08-12 NZ NZ271995A patent/NZ271995A/en not_active IP Right Cessation
- 1994-08-12 RU RU96105980A patent/RU2129556C1/ru active
- 1994-08-12 AU AU76131/94A patent/AU677428B2/en not_active Expired
- 1994-08-12 DE DE69433401T patent/DE69433401T2/de not_active Expired - Lifetime
- 1994-08-16 TW TW083107469A patent/TW269684B/zh not_active IP Right Cessation
- 1994-08-17 IL IL11068794A patent/IL110687A/en not_active IP Right Cessation
- 1994-08-17 MY MYPI94002161A patent/MY134487A/en unknown
- 1994-08-18 ZA ZA946269A patent/ZA946269B/xx unknown
1995
- 1995-08-02 JP JP8506755A patent/JP3044065B2/ja not_active Expired - Lifetime
1996
- 1996-02-16 FI FI960723A patent/FI120791B/fi not_active IP Right Cessation
- 1996-02-19 NO NO19960649A patent/NO315235B1/no not_active IP Right Cessation
1998
- 1998-07-28 US US09/123,893 patent/US6100268A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ATE256130T1 (de)	2003-12-15
CN1052006C (zh)	2000-05-03
RO116900B1 (ro)	2001-07-30
IL110687A (en)	2001-03-19
TW269684B (no)	1996-02-01
CA2168021A1 (en)	1995-02-23
HU9600373D0 (en)	1996-04-29
RU2129556C1 (ru)	1999-04-27
HU226525B1 (en)	2009-03-30
DE69433401T2 (de)	2004-09-16
JPH09501916A (ja)	1997-02-25
AU7613194A (en)	1995-03-14
US5824682A (en)	1998-10-20
ZA946269B (en)	1996-02-19
EP0714396A1 (en)	1996-06-05
AU677428B2 (en)	1997-04-24
FI120791B (fi)	2010-03-15
CZ37496A3 (en)	1996-05-15
US6100268A (en)	2000-08-08
SK19596A3 (en)	1997-02-05
CN1129451A (zh)	1996-08-21
CA2168021C (en)	2007-07-03
KR100330696B1 (ko)	2002-10-04
PL181385B1 (pl)	2001-07-31
JP3044065B2 (ja)	2000-05-22
BR9407317A (pt)	1996-04-16
DE69433401D1 (de)	2004-01-22
HUT74677A (en)	1997-01-28
NO315235B1 (no)	2003-08-04
PL313082A1 (en)	1996-05-27
CZ287771B6 (en)	2001-01-17
IL110687A0 (en)	1994-11-11
NZ271995A (en)	1996-11-26
ES2212797T3 (es)	2004-08-01
FI960723A0 (fi)	1996-02-16
FI960723A7 (fi)	1996-02-16
EP0714396B1 (en)	2003-12-10
SK282402B6 (sk)	2002-01-07
NO960649L (no)	1996-02-19
WO1995005383A1 (en)	1995-02-23
MY134487A (en)	2007-12-31

Legal Events

Date	Code	Title	Description
2014-08-25	MK1K	Patent expired

Publication	Publication Date	Title
NO960649L (no)	1996-02-19	Vasokonstriktive dehydrobenzopyranderivater
BR9407313A (pt)	1996-10-08	Ariloxialquil diaminas substituÍdas vasoconstritivas
DE3581819D1 (de)	1991-04-04	Pyridazinamine wirksam gegen viren.
DK396088A (da)	1989-01-18	Substituerede n-(3-hydroxy-4-piperidinyl)benzamider
NO20000114D0 (no)	2000-01-10	2,4,4-trisubstituerte-1,3-diokolan-antifungale midler
DK0714395T3 (da)	1999-10-11	Substituerede dihydropyranopyridiner med vasokonstriktoraktivitet