NO961442L - Fremgangsmåte til fremstilling av 1-cyklopropyl-6-fluor-1,4-dihydro-7-[(1S,4S)-5-metyl-2,5-diazabicyklo[2.2.1Å-hept-2-ylÅ-4-okso-3-kinolinkarboksylsyre og dens salter - Google Patents

Fremgangsmåte til fremstilling av 1-cyklopropyl-6-fluor-1,4-dihydro-7-[(1S,4S)-5-metyl-2,5-diazabicyklo[2.2.1Å-hept-2-ylÅ-4-okso-3-kinolinkarboksylsyre og dens salter

Info

Publication number
NO961442L
NO961442L NO961442A NO961442A NO961442L NO 961442 L NO961442 L NO 961442L NO 961442 A NO961442 A NO 961442A NO 961442 A NO961442 A NO 961442A NO 961442 L NO961442 L NO 961442L
Authority
NO
Norway
Prior art keywords
cyclopropyl
dihydro
fluoro
diazabicyclo
methyl
Prior art date
Application number
NO961442A
Other languages
English (en)
Norwegian (no)
Other versions
NO961442D0 (no
Inventor
Carlos Picornell Darder
Pedro Gonzalez Hernandez
Maria Luisa Salas Gonzalez
Original Assignee
Sint Quimica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sint Quimica Sa filed Critical Sint Quimica Sa
Publication of NO961442D0 publication Critical patent/NO961442D0/no
Publication of NO961442L publication Critical patent/NO961442L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO961442A 1995-04-12 1996-04-11 Fremgangsmåte til fremstilling av 1-cyklopropyl-6-fluor-1,4-dihydro-7-[(1S,4S)-5-metyl-2,5-diazabicyklo[2.2.1Å-hept-2-ylÅ-4-okso-3-kinolinkarboksylsyre og dens salter NO961442L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09500782A ES2092963B1 (es) 1995-04-12 1995-04-12 Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales.

Publications (2)

Publication Number Publication Date
NO961442D0 NO961442D0 (no) 1996-04-11
NO961442L true NO961442L (no) 1996-10-14

Family

ID=8290154

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961442A NO961442L (no) 1995-04-12 1996-04-11 Fremgangsmåte til fremstilling av 1-cyklopropyl-6-fluor-1,4-dihydro-7-[(1S,4S)-5-metyl-2,5-diazabicyklo[2.2.1Å-hept-2-ylÅ-4-okso-3-kinolinkarboksylsyre og dens salter

Country Status (13)

Country Link
KR (1) KR960037676A (de)
AR (1) AR001560A1 (de)
AT (1) ATA65396A (de)
CZ (1) CZ97496A3 (de)
ES (1) ES2092963B1 (de)
FI (1) FI961583L (de)
GR (1) GR960100116A (de)
HU (1) HUP9600941A3 (de)
MX (1) MX9601351A (de)
NO (1) NO961442L (de)
PL (1) PL313697A1 (de)
PT (1) PT101864B (de)
SK (1) SK46896A3 (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166416B (de) * 1985-09-18 1990-05-05 Pfizer
HU196218B (en) * 1985-12-09 1988-10-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing quinoline carboxylic acid boric acid anhydrides
CA1306750C (en) * 1985-12-09 1992-08-25 Istvan Hermecz Process for the preparation of quinoline carboxylic acide
EP0251308B1 (de) * 1986-07-04 1990-11-22 Chemie Linz Gesellschaft m.b.H. 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
GR1000469B (el) * 1987-04-08 1992-07-30 Chinoin Gyogyszer Es Vegyeszet Mεθοδος παρασκευης κινολινοκαρβοξυλικων οξεων.
HU198709B (en) * 1987-04-08 1989-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing quinoline-carboxylic acid derivatives
YU46451B (sh) * 1987-04-08 1993-10-20 Chinoin Gyogyszer Es Vegyeszeti Ter Mekek Gyara Rt. Postupak za dobivanje mešovitih anhidrida hinolin-karboksilne i borne kiseline
EP0329719A1 (de) * 1987-06-24 1989-08-30 CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. Verfahren zur herstellung von chinolincarbonsäure abkömmlingen
HU203746B (en) * 1988-12-22 1991-09-30 Chinoin Gyogyszer Es Vegyeszet Process for producing quinoline-carboxylic acid derivatives
JPH0778065B2 (ja) * 1990-07-06 1995-08-23 杏林製薬株式会社 （６，７―置換―８―アルコキシ―１―シクロプロピル―１，４―ジヒドロ―４―オキソ―３―キノリンカルボン酸―ｏ▲上３▼，ｏ▲上４▼）ビス（アシルオキシ―ｏ）ホウ素化合物及びその塩並びにその製造方法

Also Published As

Publication number Publication date
PT101864A (pt) 1997-01-31
HUP9600941A3 (en) 1998-01-28
PT101864B (pt) 1997-12-31
FI961583A0 (fi) 1996-04-11
FI961583A7 (fi) 1996-10-13
MX9601351A (es) 1997-04-30
HU9600941D0 (en) 1996-06-28
CZ97496A3 (en) 1996-10-16
AR001560A1 (es) 1997-11-26
KR960037676A (ko) 1996-11-19
PL313697A1 (en) 1996-10-14
ES2092963B1 (es) 1997-12-16
ATA65396A (de) 1998-09-15
HUP9600941A2 (en) 1997-06-30
FI961583L (fi) 1996-10-13
ES2092963A1 (es) 1996-12-01
NO961442D0 (no) 1996-04-11
SK46896A3 (en) 1997-07-09
GR960100116A (el) 1996-12-31

Similar Documents

Publication Publication Date Title
Ghosh et al. Synthesis and optical resolution of high affinity P2-ligands for HIV-1 protease inhibitors
Narasaka et al. Total synthesis of a macrocyclic pyrrolizidine alkaloid,(.+-.)-integerrimine, utilizing an activable protecting group
KR860004026A (ko) 알킬-1-시클로프로필-1,4-디히드로-4-옥소-3-퀴놀린 카르복실산의 제조방법
EP0641862A3 (de) Verfahren zur Herstellung von Trans-4-Hydroxy-1-Proline.
DE59405676D1 (de) Herstellung von Carbonsäurehalogeniden und Carboxylat-Salzen
PT1466905E (pt) Processo para a produção de éster do ácido oxo-heptenóico opticamente activo
Donohoe et al. Stereoselectivity in the Birch reduction of 2-furoic acid derivatives
Schoenleber et al. Relative stereochemistry of the A ring of plant bile pigments
NO991500L (no) FremgangsmÕte til fremstilling av esterifiseringsprodukter
HUT46742A (en) Process for production of esthers of carbonic acid
Zhou et al. Synthesis of (±)-and (-)-Vibralactone and Vibralactone C
NO970388D0 (no) Fremgangsmåte for fremstilling av et kjemisk produkt
AU581185B2 (en) Process for the racemization of optically active aminoacids
AU6949691A (en) Process for the enantioselection synthesis of alkylated oxindoles used as intermediates in the preparation of physostigmine
IN187905B (de)
ES8106708A1 (es) Un procedimiento para preparar 7-alcoxicarbonil-6,8-dime- til-4-hidroximetil-1-ftalazona
Rozzell Preparation of diastereomeric 2-deuterio-3-hydroxy butyrate. A general method for hydrogenation of β-acyloxy-α, β-unsaturated crotonates
Kobayashi et al. A Chemo-Enzymatic Expeditious Route to Racemic Dihexanoyl (2R*, 3R*, 4R*)-Dehydroxymethylepoxyquinomycin (DHMEQ), the Precursor for Lipase-Catalyzed Synthesis of the Potent Nuclear Factor-κB Inhibitor,(2S, 3S, 4S)-DHMEQ
ES2092963A1 (es) Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales.
Behrman The bacterial oxidation of nicotinic acid: N-Formylmaleamic and N-formylfumaramic acids
WO2002062781A1 (en) Preparation of isocoumarin derivatives and intermediates for the synthesis thereof
FI861238A0 (fi) Foerfarande foer framstaellning av kinolin-3-karboxylsyror.
AU559033B2 (en) Preparation of n-phosphonomethylglycine
CA2069130A1 (en) Continuous process for the preparation of sucrose 6-esters
Chaudhry et al. Chemistry of pyrrolic compounds. XXXVI. Some aspects of the chemistry of 2'-hydroxypropionate porphyrins: new syntheses of harderoporphyrin trimethyl ester,'S-411 porphyrin'trimethyl ester and related compounds