NO962017L - 5,6-Dihydropyron - derivater som protease-inhibitorer og antivirus-midler - Google Patents
5,6-Dihydropyron - derivater som protease-inhibitorer og antivirus-midlerInfo
- Publication number
- NO962017L NO962017L NO962017A NO962017A NO962017L NO 962017 L NO962017 L NO 962017L NO 962017 A NO962017 A NO 962017A NO 962017 A NO962017 A NO 962017A NO 962017 L NO962017 L NO 962017L
- Authority
- NO
- Norway
- Prior art keywords
- dihydropyrone
- derivatives
- antivirals
- protease inhibitors
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15544393A | 1993-11-19 | 1993-11-19 | |
| US08/319,820 US5840751A (en) | 1993-11-19 | 1994-10-12 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
| PCT/US1994/012269 WO1995014012A1 (en) | 1993-11-19 | 1994-10-26 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO962017D0 NO962017D0 (no) | 1996-05-15 |
| NO962017L true NO962017L (no) | 1996-07-08 |
| NO316172B1 NO316172B1 (no) | 2003-12-22 |
Family
ID=26852338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19962017A NO316172B1 (no) | 1993-11-19 | 1996-05-15 | 5,6-dihydropyron-derivater og farmasöytisk blanding |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0729464A1 (no) |
| JP (1) | JP3684426B2 (no) |
| AT (1) | ATE263761T1 (no) |
| AU (1) | AU689158B2 (no) |
| CA (1) | CA2176043A1 (no) |
| DE (1) | DE69433705T2 (no) |
| DK (1) | DK1142887T3 (no) |
| ES (1) | ES2219457T3 (no) |
| FI (1) | FI962022L (no) |
| HR (1) | HRP940935B1 (no) |
| HU (1) | HUT77668A (no) |
| IL (1) | IL111674A0 (no) |
| NO (1) | NO316172B1 (no) |
| NZ (1) | NZ275961A (no) |
| PT (1) | PT1142887E (no) |
| RU (1) | RU2140917C1 (no) |
| SI (1) | SI1142887T1 (no) |
| WO (1) | WO1995014012A1 (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050046718A (ko) * | 1995-08-11 | 2005-05-18 | 제논 인바이런멘탈 인코포레이티드 | 수직한 중공사 멤브레인 다발 및 섬유 표면을 깨끗하게유지시키는 방법 |
| US5834506A (en) * | 1996-11-01 | 1998-11-10 | Warner-Lambert Company | Dihydropyrones with improved antiviral activity |
| CZ298847B6 (cs) * | 1997-09-11 | 2008-02-27 | Pharmacia & Upjohn Company | Zpusob výroby proteázového inhibitoru |
| CA2339275A1 (en) * | 1998-09-11 | 2000-03-23 | Warner-Lambert Company | 5,6-dihydro-4-hydroxy-2-pyranones as hiv aspartyl protease inhibitors |
| US6288235B1 (en) | 1999-04-14 | 2001-09-11 | Ortho-Mcneil Pharmaceutical, Inc. | Methods for the synthesis of highly substituted 2,4-dioxopiperidine libraries |
| DE10030094A1 (de) * | 2000-06-19 | 2001-12-20 | Bayer Ag | Phenylsubstituierte 5,6-Dihydro-pyron-Derivate |
| US6710058B2 (en) | 2000-11-06 | 2004-03-23 | Bristol-Myers Squibb Pharma Company | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors |
| DE10108471C1 (de) | 2001-02-22 | 2002-11-21 | Boehringer Ingelheim Pharma | Kontinuierliches Verfahren zur Herstellung von 5,6-Dihydro-4-hydroxy-2-pyronen |
| US7141681B2 (en) | 2001-02-22 | 2006-11-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Continuous process for preparing dihydropyrones |
| US6500963B2 (en) | 2001-02-22 | 2002-12-31 | Boehringer Ingelheim Pharma Kg | Process for preparing optically active dihydropyrones |
| DE10108470A1 (de) * | 2001-02-22 | 2002-09-05 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung optisch aktiver Dihydropyrone |
| TW200307667A (en) | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
| DOP2003000641A (es) | 2002-05-10 | 2003-11-15 | Pfizer | Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan |
| TW200500341A (en) * | 2002-11-12 | 2005-01-01 | Astrazeneca Ab | Novel compounds |
| US7148226B2 (en) | 2003-02-21 | 2006-12-12 | Agouron Pharmaceuticals, Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
| SE0302487D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| AU2005273619B2 (en) | 2004-08-18 | 2009-05-28 | Pfizer Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
| DE102005059469A1 (de) | 2005-12-13 | 2007-06-14 | Bayer Cropscience Ag | Insektizide Zusammensetzungen mit verbesserter Wirkung |
| DE102006007882A1 (de) | 2006-02-21 | 2007-08-30 | Bayer Cropscience Ag | Cycloalkyl-phenylsubstituierte cyclische Ketoenole |
| PL2032551T3 (pl) * | 2006-06-16 | 2012-01-31 | Pharma Mar Sa | Przeciwnowotworowe związki dihydropiran-2-onu |
| BRPI1008949B1 (pt) | 2009-03-11 | 2018-07-10 | Bayer Intellectual Property Gmbh | Cetoenóis haloalquilmetilenóxi-fenil-substituídos e seu uso, composição, seu uso e seu método de produção, métodos para combate de pestes animais e/ou crescimento de plantas indesejadas |
| DE102010008644A1 (de) | 2010-02-15 | 2011-08-18 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Zyklische Ketoenole zur Therapie |
| RU2461555C1 (ru) * | 2011-07-07 | 2012-09-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | Способ получения 5-арил-3-фенил-2-оксаспиро[5,6]додец-3-ен-1-онов, проявляющих анальгетическую активность |
| UA113753C2 (xx) | 2012-01-26 | 2017-03-10 | Фенілзаміщені кетоеноли для боротьби з паразитами риб | |
| ES2613875T3 (es) | 2012-11-28 | 2017-05-26 | Sumitomo Chemical Co., Ltd | Compuestos de dihidropirona y herbicidas que los comprenden |
| SE539512C2 (sv) | 2015-12-02 | 2017-10-03 | Ultupharma Ab | Compounds and methods of treating bacterial infections |
| CN115916752B (zh) * | 2020-06-26 | 2025-05-06 | 日本农药株式会社 | 芳基四氢吡啶衍生物或其盐类、和含有该化合物的杀虫剂及其使用方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3818046A (en) * | 1972-12-18 | 1974-06-18 | Dow Chemical Co | Sulfur-containing hydroxy pyrones and alkali metal salts thereof |
| CH617569A5 (en) * | 1975-09-29 | 1980-06-13 | Ciba Geigy Ag | Pesticides containing, as active ingredient, a 3-N-phenyl-carbamoyl-4-hydroxy-1,2-(benzo)pyrone derivative. |
| SU950728A1 (ru) * | 1981-01-23 | 1982-08-15 | Пермский государственный фармацевтический институт | Способ получени 6-арил-3-ароил-4-окси-5-бромпиран-2-онов |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
-
1994
- 1994-10-26 RU RU96113098/04A patent/RU2140917C1/ru not_active IP Right Cessation
- 1994-10-26 EP EP95900429A patent/EP0729464A1/en not_active Withdrawn
- 1994-10-26 JP JP51445895A patent/JP3684426B2/ja not_active Expired - Fee Related
- 1994-10-26 DK DK01114943T patent/DK1142887T3/da active
- 1994-10-26 AT AT01114943T patent/ATE263761T1/de not_active IP Right Cessation
- 1994-10-26 CA CA002176043A patent/CA2176043A1/en not_active Abandoned
- 1994-10-26 AU AU81256/94A patent/AU689158B2/en not_active Ceased
- 1994-10-26 FI FI962022A patent/FI962022L/fi unknown
- 1994-10-26 ES ES01114943T patent/ES2219457T3/es not_active Expired - Lifetime
- 1994-10-26 HU HU9601348A patent/HUT77668A/hu not_active Application Discontinuation
- 1994-10-26 SI SI9430463T patent/SI1142887T1/xx unknown
- 1994-10-26 DE DE69433705T patent/DE69433705T2/de not_active Expired - Fee Related
- 1994-10-26 WO PCT/US1994/012269 patent/WO1995014012A1/en not_active Ceased
- 1994-10-26 PT PT01114943T patent/PT1142887E/pt unknown
- 1994-10-26 NZ NZ275961A patent/NZ275961A/en unknown
- 1994-11-17 IL IL11167494A patent/IL111674A0/xx unknown
- 1994-11-17 HR HR940935A patent/HRP940935B1/xx not_active IP Right Cessation
-
1996
- 1996-05-15 NO NO19962017A patent/NO316172B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995014012A1 (en) | 1995-05-26 |
| CA2176043A1 (en) | 1995-05-26 |
| PT1142887E (pt) | 2004-08-31 |
| HU9601348D0 (en) | 1996-07-29 |
| DK1142887T3 (da) | 2004-06-21 |
| SI1142887T1 (en) | 2004-08-31 |
| AU689158B2 (en) | 1998-03-26 |
| JP3684426B2 (ja) | 2005-08-17 |
| DE69433705T2 (de) | 2005-03-10 |
| EP0729464A1 (en) | 1996-09-04 |
| FI962022A7 (fi) | 1996-07-12 |
| RU2140917C1 (ru) | 1999-11-10 |
| DE69433705D1 (de) | 2004-05-13 |
| AU8125694A (en) | 1995-06-06 |
| FI962022L (fi) | 1996-07-12 |
| FI962022A0 (fi) | 1996-05-13 |
| IL111674A0 (en) | 1995-01-24 |
| HRP940935B1 (en) | 2004-08-31 |
| HRP940935A2 (en) | 1997-04-30 |
| NO962017D0 (no) | 1996-05-15 |
| JPH09505294A (ja) | 1997-05-27 |
| NO316172B1 (no) | 2003-12-22 |
| NZ275961A (en) | 2001-11-30 |
| ATE263761T1 (de) | 2004-04-15 |
| ES2219457T3 (es) | 2004-12-01 |
| HUT77668A (hu) | 1998-07-28 |
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| Publication | Publication Date | Title |
|---|---|---|
| NO962017D0 (no) | 5,6-Dihydropyron - derivater som protease-inhibitorer og antivirus-midler | |
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| NO20003233L (no) | 4-hydroksykinolin-3-karboksamider og hydrazider som antivirale midler | |
| FI915819A0 (fi) | Hiv- proteas-inhibitorer. | |
| MD960171A (ro) | Derivaţi ai pironei folosiţi ca inhibitori ai proteazei şi agenţi antivirali | |
| NO983991L (no) | Serin-protease-inhibitorer | |
| DK0729465T3 (da) | Pyronderivater som proteaseinhibitorer og antivirale midler | |
| WO1995014014A3 (en) | Pyrone derivatives as protease inhibitors and antiviral agents | |
| ATE238062T1 (de) | Hemmung von hiv-infektion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |