NO963224L - Farmasöytisk aktive forbindelser og liposomer og fremgangsmåter for anvendelse derav - Google Patents

Farmasöytisk aktive forbindelser og liposomer og fremgangsmåter for anvendelse derav

Info

Publication number: NO963224L
Authority: NO; Norway
Prior art keywords: group; chain; liposomes; methods; active compounds
Prior art date: 1994-02-02

Application number

NO963224A

Other languages

English (en)

Other versions

NO314405B1 (no

NO963224D0 (no

Inventor

Yong-Wei Pei

Eric Mayhew

Imran Ahmad

Andrew Stuart Janoff

Original Assignee

Liposome Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-02

Filing date

1996-08-01

Publication date

1996-09-27

1996-08-01 Application filed by Liposome Co Inc filed Critical Liposome Co Inc

1996-08-01 Publication of NO963224D0 publication Critical patent/NO963224D0/no

1996-09-27 Publication of NO963224L publication Critical patent/NO963224L/no

2003-03-17 Publication of NO314405B1 publication Critical patent/NO314405B1/no

Links

150000001875 compounds Chemical class 0.000 title abstract 2
239000002502 liposome Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
125000001931 aliphatic group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 3
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000000304 alkynyl group Chemical group 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 2
230000002401 inhibitory effect Effects 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Manufacturing Of Micro-Capsules (AREA)

NO19963224A 1994-02-02 1996-08-01 Farmasöytisk aktive forbindelser og liposomer og anvendelse derav NO314405B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19029594A	1994-02-02	1994-02-02
PCT/US1995/001490 WO1995021175A1 (en)	1994-02-02	1995-02-02	Pharmaceutically active compounds and liposomes, and methods of use therof

Publications (3)

Publication Number	Publication Date
NO963224D0 NO963224D0 (no)	1996-08-01
NO963224L true NO963224L (no)	1996-09-27
NO314405B1 NO314405B1 (no)	2003-03-17

Family

ID=22700754

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19963224A NO314405B1 (no)	1994-02-02	1996-08-01	Farmasöytisk aktive forbindelser og liposomer og anvendelse derav

Country Status (14)

Country	Link
US (3)	US5631394A (no)
EP (2)	EP1008342A3 (no)
JP (1)	JPH09508900A (no)
AT (1)	ATE195944T1 (no)
AU (1)	AU691886B2 (no)
CA (1)	CA2182485A1 (no)
DE (1)	DE69518627T2 (no)
DK (1)	DK0742789T3 (no)
ES (1)	ES2149350T3 (no)
FI (1)	FI116620B (no)
GR (1)	GR3034521T3 (no)
NO (1)	NO314405B1 (no)
PT (1)	PT742789E (no)
WO (1)	WO1995021175A1 (no)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6255336B1 (en)	1995-09-20	2001-07-03	The Regents Of The University Of Michigan	Amino ceramide-like compounds and therapeutic methods of use
US5916911A (en) *	1995-09-20	1999-06-29	The Regents Of The University Of Michigan	Amino ceramide--like compounds and therapeutic methods of use
US5834016A (en) *	1996-04-04	1998-11-10	Cilag Ag	Liposome-based topical vitamin D formulation
US6274309B1 (en) *	1996-07-26	2001-08-14	Richard Kolesnick	Method for the modulation of acid-sphingomyelinase-related apoptosis
CN1055640C (zh) *	1996-11-29	2000-08-23	沃维汉	人降钙素基因相关肽脂质体组合物及其制法
US6982142B2 (en)	1997-12-01	2006-01-03	John Wayne Cancer Institute	Methods for screening therapeutically effective agents
ATE334686T1 (de) *	1999-03-25	2006-08-15	Ct Molecular Med & Immunology	Sphingomyelin enthaltende zusammensetzung zur verbesserung der tumortherapie
US7683044B2 (en)	1999-03-25	2010-03-23	Center For Molecular Medicine And Immunology	Sphingomyelin therapy of autoimmune disease
US7820718B1 (en) *	1999-04-07	2010-10-26	Roger Williams Hospital	Combinations of ceramide and chemotherapeutic agents for inducing cell death and uses thereof in treating cancer
TW502133B (en)	1999-06-10	2002-09-11	Wako Pure Chem Ind Ltd	Resist composition, agent and method for reducing substrate dependence thereof
US6682545B1 (en) *	1999-10-06	2004-01-27	The Penn State Research Foundation	System and device for preventing restenosis in body vessels
WO2001038295A1 (fr) *	1999-11-24	2001-05-31	Taisho Pharmaceutical Co.,Ltd.	Derives de sphingosine
US6410597B1 (en) *	2000-02-25	2002-06-25	Virginia Commonwealth University	Hydroxyalkyl amide analogs of ceramide
WO2002051439A2 (en)	2000-12-22	2002-07-04	Medlyte, Inc.	Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor
PT2266968E (pt) *	2001-07-16	2013-02-25	Genzyme Corp	Síntese de udp-glucose: inibidores de n-acil esfingosinaglucosiltransferase
EP1287815A1 (en) *	2001-08-31	2003-03-05	Cosmoferm B.V.	Use of a sphingoid base for inhibiting ceramidase activity
US20060217560A1 (en) *	2002-04-29	2006-09-28	Shayman James A	Amino ceramide-like compounds and therapeutic methods of use
US6916802B2 (en) *	2002-04-29	2005-07-12	Genzyme Corporation	Amino ceramide-like compounds and therapeutic methods of use
US20070031480A1 (en) *	2003-03-07	2007-02-08	Lawrence Mayer	Enhanced delivery of sphingolipids
EP1610763A2 (en) *	2003-03-31	2006-01-04	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Stable liposomes or micelles comprising a sphingolipid and a peg-lipopolymer
JP5107573B2 (ja)	2003-04-25	2012-12-26	ザペンステイトリサーチファウンデーション	増殖抑制性脂質由来生物活性化合物の全身送達方法およびシステム
US7906122B2 (en)	2003-06-18	2011-03-15	Yissum Research Development Company Of The Hebrew University Of Jersusalem	Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination
AU2004246904B2 (en)	2003-06-18	2010-02-04	Biolab Ltd.	Sphingolipids polyalkylamine conjugates for use in transfection
US7794713B2 (en)	2004-04-07	2010-09-14	Lpath, Inc.	Compositions and methods for the treatment and prevention of hyperproliferative diseases
JP2008519840A (ja)	2004-11-10	2008-06-12	ジェンザイム・コーポレイション	糖尿病の処置方法
CN101102752A (zh) *	2004-11-15	2008-01-09	耶路撒冷希伯来大学伊萨姆研发公司	联合优选为神经酰胺与细胞毒性药物的联合疗法
JP4791082B2 (ja) *	2005-05-30	2011-10-12	株式会社クラレ	リポソームおよびそれを含む皮膚外用剤
WO2007044748A2 (en) *	2005-10-11	2007-04-19	University Of Pittsburgh	Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
WO2007134086A2 (en) *	2006-05-09	2007-11-22	Genzyme Corporation	Methods of treating fatty liver disease comprising inhibiting glucosphingolipid synthesis
US9274130B2 (en)	2006-05-31	2016-03-01	Lpath, Inc.	Prevention and treatment of pain using antibodies to lysophosphatidic acid
US20080138334A1 (en)	2006-05-31	2008-06-12	Sabbadini Roger A	Immune-Derived Moieties Reactive Against Bioactive Lipids, and Methods of Making and Using Same
US7862812B2 (en)	2006-05-31	2011-01-04	Lpath, Inc.	Methods for decreasing immune response and treating immune conditions
US9274129B2 (en)	2006-05-31	2016-03-01	Lpath, Inc.	Methods and reagents for detecting bioactive lipids
US8796429B2 (en)	2006-05-31	2014-08-05	Lpath, Inc.	Bioactive lipid derivatives, and methods of making and using same
CA2667706A1 (en)	2006-10-27	2008-05-08	Lpath, Inc.	Compositions and methods for treating ocular diseases and conditions
DK2087002T3 (da)	2006-10-27	2014-10-27	Lpath Inc	Sammensætninger og fremgangsmåder til binding af sphingosin-1-phosphat
EP2594562B1 (en)	2007-05-31	2016-07-20	Genzyme Corporation	2-acylaminopropanol-type glucosylceramide synthase inhibitors
KR101640263B1 (ko)	2007-10-05	2016-07-15	젠자임 코포레이션	세라마이드 유도체로 다낭성 신장질환을 치료하는 방법
WO2009132082A2 (en) *	2008-04-22	2009-10-29	Medical College Of Georgia Research Institute, Inc.	Immunogenic compositions containing ceramide and methods of use thereof
JP2011529500A (ja)	2008-07-28	2011-12-08	ジェンザイムコーポレーション	虚脱性糸球体症および他の糸球体疾患の処置のためのグルコシルセラミドシンターゼ阻害
US8309593B2 (en)	2008-10-03	2012-11-13	Genzyme Corporation	2-acylaminopropoanol-type glucosylceramide synthase inhibitors
SG10201407881WA (en)	2009-11-27	2015-01-29	Genzyme Corp	An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
US9207232B2 (en) *	2011-08-15	2015-12-08	National University Corporation Chiba University	Ceramide derivative and Golgi apparatus-labeling fluorescent probe using same
KR102423002B1 (ko) *	2021-02-17	2022-07-21	주식회사 엘씨에스바이오텍	신규 세라마이드, 그의 제조방법 및 그의 용도

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4522803A (en) *	1983-02-04	1985-06-11	The Liposome Company, Inc.	Stable plurilamellar vesicles, their preparation and use
US5169637A (en) *	1983-03-24	1992-12-08	The Liposome Company, Inc.	Stable plurilamellar vesicles
US5030453A (en) *	1983-03-24	1991-07-09	The Liposome Company, Inc.	Stable plurilamellar vesicles
US4588578A (en) *	1983-08-08	1986-05-13	The Liposome Company, Inc.	Lipid vesicles prepared in a monophase
US4721612A (en) *	1984-04-12	1988-01-26	The Liposome Company, Inc.	Steroidal liposomes
US5008050A (en) *	1984-06-20	1991-04-16	The Liposome Company, Inc.	Extrusion technique for producing unilamellar vesicles
US5077056A (en) *	1984-08-08	1991-12-31	The Liposome Company, Inc.	Encapsulation of antineoplastic agents in liposomes
US5059421A (en) *	1985-07-26	1991-10-22	The Liposome Company, Inc.	Preparation of targeted liposome systems of a defined size distribution
US4975282A (en) *	1985-06-26	1990-12-04	The Liposome Company, Inc.	Multilamellar liposomes having improved trapping efficiencies
JP2588729B2 (ja) *	1987-10-05	1997-03-12	塩野義製薬株式会社	スフィンゴシン誘導体
FR2637598B1 (fr) *	1988-10-06	1991-10-11	Agronomique Inst Nat Rech	Nouveaux sphingophospholipides a inositol, leur obtention, et leur application comme inducteurs de resistance a diverses maladies cryptogamiques chez les vegetaux
US5100662A (en) *	1989-08-23	1992-03-31	The Liposome Company, Inc.	Steroidal liposomes exhibiting enhanced stability
DE4021082C2 (de) *	1990-07-03	1995-08-17	Hans Dr Lautenschlaeger	Hautbehandlungsmittel mit hohen Lipidgehalten unter Verwendung eines Bilayer enthaltenden Systems, Salzen organischer Säuren, Alkohol und Stabilisator
JPH05508863A (ja) *	1990-08-13	1993-12-09	デューク・ユニバーシティ	セラミドを使用して細胞分裂を誘導する方法
GB9022921D0 (en) *	1990-10-22	1990-12-05	Unilever Plc	Cosmetic composition
GB9100816D0 (en) *	1991-01-15	1991-02-27	Unilever Plc	Cosmetic composition
DE4201461A1 (de) *	1992-01-21	1993-07-22	Mueller Schulte Detlef Dr	Mittel fuer die selektive tumortherapie auf der basis ferromagnetischer partikel - verfahren zu ihrer herstellung und verwendung

1995
- 1995-02-02 EP EP00102434A patent/EP1008342A3/en not_active Withdrawn
- 1995-02-02 EP EP95910923A patent/EP0742789B1/en not_active Expired - Lifetime
- 1995-02-02 WO PCT/US1995/001490 patent/WO1995021175A1/en not_active Ceased
- 1995-02-02 DE DE69518627T patent/DE69518627T2/de not_active Expired - Fee Related
- 1995-02-02 DK DK95910923T patent/DK0742789T3/da active
- 1995-02-02 ES ES95910923T patent/ES2149350T3/es not_active Expired - Lifetime
- 1995-02-02 PT PT95910923T patent/PT742789E/pt unknown
- 1995-02-02 US US08/383,291 patent/US5631394A/en not_active Expired - Fee Related
- 1995-02-02 JP JP7520799A patent/JPH09508900A/ja not_active Ceased
- 1995-02-02 AT AT95910923T patent/ATE195944T1/de not_active IP Right Cessation
- 1995-02-02 CA CA002182485A patent/CA2182485A1/en not_active Abandoned
- 1995-02-02 AU AU18712/95A patent/AU691886B2/en not_active Ceased
- 1995-10-19 US US08/547,688 patent/US5677337A/en not_active Expired - Lifetime
- 1995-10-19 US US08/545,164 patent/US5681589A/en not_active Expired - Lifetime
1996
- 1996-08-01 FI FI963045A patent/FI116620B/fi not_active IP Right Cessation
- 1996-08-01 NO NO19963224A patent/NO314405B1/no unknown
2000
- 2000-09-29 GR GR20000402211T patent/GR3034521T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0742789T3 (da)	2000-11-13
CA2182485A1 (en)	1995-08-10
FI963045L (fi)	1996-08-01
DE69518627T2 (de)	2001-01-11
GR3034521T3 (en)	2000-12-29
WO1995021175A1 (en)	1995-08-10
US5677337A (en)	1997-10-14
PT742789E (pt)	2000-12-29
EP1008342A3 (en)	2004-12-29
EP0742789B1 (en)	2000-08-30
US5631394A (en)	1997-05-20
DE69518627D1 (de)	2000-10-05
FI116620B (fi)	2006-01-13
EP1008342A2 (en)	2000-06-14
NO314405B1 (no)	2003-03-17
ATE195944T1 (de)	2000-09-15
NO963224D0 (no)	1996-08-01
AU1871295A (en)	1995-08-21
EP0742789A1 (en)	1996-11-20
AU691886B2 (en)	1998-05-28
ES2149350T3 (es)	2000-11-01
US5681589A (en)	1997-10-28
JPH09508900A (ja)	1997-09-09
FI963045A0 (fi)	1996-08-01

Publication	Publication Date	Title
NO963224D0 (no)	1996-08-01	Farmasöytisk aktive forbindelser og liposomer og fremgangsmåter for anvendelse derav
IL94444A0 (en)	1991-03-10	Retroviral protease inhibiting compounds
KR950010888A (ko)	1995-05-15	평활근세포 증식 및 재발협착증을 억제하는 방법
GB9822376D0 (en)	1998-12-09	Stabilizer compounds
GR3032083T3 (en)	2000-03-31	Immunosuppressant and antiallergic compounds, e.g. n-(3-oxohexanoyl) homoserine lactone
ZA9710292B (en)	1999-05-17	Atherosclerosis treatment
ZA200108124B (en)	2003-03-26	Pharmaceutical compounds.
ATE172463T1 (de)	1998-11-15	Pyrrolocarbazol
EP0696585A4 (no)	1996-03-27
DK354689D0 (da)	1989-07-18	Bu-3608 derivater
EP0381235A3 (en)	1991-04-03	Pyrrolidine compound and pharmaceutical use
HU9501466D0 (en)	1995-06-28	Glycopyranoside benzothiophenes
EA199900684A1 (ru)	2000-04-24	Производные иминоазаантрациклинона для лечения амилоидоза
IL69448A (en)	1986-09-30	Process for combating phytopathogenic fungi with azolylphenoxy-tetrahydrofuran-2-ylidene methane derivatives
TW275629B (no)	1996-05-11
DE69905144D1 (de)	2003-03-06	N,N'-Diacylthiocystine
ZA9510964B (en)	1996-06-08	Antiherpes peptidomimetic compounds
GB9617822D0 (en)	1996-10-09	Pharmaceutical compounds