NO963254L - Makrocykliske difluorstatonderivater som er anvendbare som antivirale midler - Google Patents

Makrocykliske difluorstatonderivater som er anvendbare som antivirale midler

Info

Publication number
NO963254L
NO963254L NO963254A NO963254A NO963254L NO 963254 L NO963254 L NO 963254L NO 963254 A NO963254 A NO 963254A NO 963254 A NO963254 A NO 963254A NO 963254 L NO963254 L NO 963254L
Authority
NO
Norway
Prior art keywords
alkyl
hydrogen
piperazinyl
hydroxy
phenyl
Prior art date
Application number
NO963254A
Other languages
English (en)
Norwegian (no)
Other versions
NO963254D0 (no
Inventor
Robert Allan Farr
Brent Ludvick Podlogar
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of NO963254D0 publication Critical patent/NO963254D0/no
Publication of NO963254L publication Critical patent/NO963254L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO963254A 1994-02-04 1996-08-02 Makrocykliske difluorstatonderivater som er anvendbare som antivirale midler NO963254L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19208094A 1994-02-04 1994-02-04
PCT/US1994/013711 WO1995021186A1 (fr) 1994-02-04 1994-11-28 Derives de difluorostatone macrocyclique utiles en tant qu'agents antiviraux

Publications (2)

Publication Number Publication Date
NO963254D0 NO963254D0 (no) 1996-08-02
NO963254L true NO963254L (no) 1996-08-02

Family

ID=22708156

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963254A NO963254L (no) 1994-02-04 1996-08-02 Makrocykliske difluorstatonderivater som er anvendbare som antivirale midler

Country Status (20)

Country Link
US (1) US5969132A (fr)
EP (1) EP0742791B1 (fr)
JP (1) JP3574455B2 (fr)
KR (1) KR100367379B1 (fr)
CN (1) CN1142830A (fr)
AT (1) ATE198602T1 (fr)
AU (1) AU684875B2 (fr)
CA (1) CA2182476C (fr)
DE (1) DE69426574T2 (fr)
DK (1) DK0742791T3 (fr)
ES (1) ES2155515T3 (fr)
FI (1) FI963073L (fr)
GR (1) GR3035623T3 (fr)
HU (1) HUT74384A (fr)
IL (1) IL112514A0 (fr)
NO (1) NO963254L (fr)
NZ (1) NZ277410A (fr)
PT (1) PT742791E (fr)
WO (1) WO1995021186A1 (fr)
ZA (1) ZA95756B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2528375C (fr) 2003-06-18 2013-11-19 Tranzyme Pharma, Inc. Antagonistes macrocycliques du recepteur de motiline

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH672792A5 (fr) * 1985-02-19 1989-12-29 Sandoz Ag
DE3674131D1 (de) * 1985-04-19 1990-10-18 Upjohn Co Substituierte dihalo-statin-reninhemmungsmittel.
FI910084A0 (fi) * 1988-07-08 1991-01-07 Smithkline Beckman Corp Retrovirala proteaser bindande peptider.
US5071837A (en) * 1990-11-28 1991-12-10 Warner-Lambert Company Novel renin inhibiting peptides
NZ241099A (en) * 1991-01-02 1994-08-26 Merrell Dow Pharma Difluorostatone analogues and derivatives and pharmaceutical compositions
EP0773926A1 (fr) * 1994-07-15 1997-05-21 Merrell Pharmaceuticals Inc. Agents antiviraux a base de difluorostatone

Also Published As

Publication number Publication date
ZA95756B (en) 1995-10-05
NO963254D0 (no) 1996-08-02
PT742791E (pt) 2001-06-29
AU1262295A (en) 1995-08-21
HUT74384A (en) 1996-12-30
KR100367379B1 (ko) 2003-04-11
HU9602158D0 (en) 1996-09-30
FI963073A0 (fi) 1996-08-02
CA2182476C (fr) 2000-12-26
GR3035623T3 (en) 2001-06-29
CN1142830A (zh) 1997-02-12
JPH09508417A (ja) 1997-08-26
FI963073A7 (fi) 1996-08-02
NZ277410A (en) 1997-02-24
JP3574455B2 (ja) 2004-10-06
IL112514A0 (en) 1995-05-26
ES2155515T3 (es) 2001-05-16
DE69426574D1 (de) 2001-02-15
EP0742791B1 (fr) 2001-01-10
AU684875B2 (en) 1998-01-08
DE69426574T2 (de) 2001-08-09
ATE198602T1 (de) 2001-01-15
DK0742791T3 (da) 2001-04-02
US5969132A (en) 1999-10-19
EP0742791A1 (fr) 1996-11-20
WO1995021186A1 (fr) 1995-08-10
FI963073L (fi) 1996-08-02

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application