NO964652L - Fremgangsmåte for fremstilling av 1-(3-trialkylsilyl-fenyl)-2,2,2-trifluormetyletanonderivater - Google Patents

Fremgangsmåte for fremstilling av 1-(3-trialkylsilyl-fenyl)-2,2,2-trifluormetyletanonderivater

Info

Publication number
NO964652L
NO964652L NO964652A NO964652A NO964652L NO 964652 L NO964652 L NO 964652L NO 964652 A NO964652 A NO 964652A NO 964652 A NO964652 A NO 964652A NO 964652 L NO964652 L NO 964652L
Authority
NO
Norway
Prior art keywords
preparation
trifluoromethylethanone
trialkylsilyl
phenyl
derivatives
Prior art date
Application number
NO964652A
Other languages
English (en)
Other versions
NO964652D0 (no
Inventor
Richard Appleby Wolf
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of NO964652L publication Critical patent/NO964652L/no
Publication of NO964652D0 publication Critical patent/NO964652D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/0825—Preparations of compounds not comprising Si-Si or Si-cyano linkages
    • C07F7/083—Syntheses without formation of a Si-C bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Foreliggende oppfinnelse an- går en ny fremgangsmåte for fremstil- ling av l-(3-trialkylsilylfenyl)-2,2,2- trifluormetyletanoner som er anvendbare for behandling av Alzheimers sykdom og senil demens som beskrevet av Schirlin et al. i europeisk patentsøknad, publi- kasjonsnr. O 409 676, publisert 23. januar 1991.
NO964652A 1994-05-05 1996-11-04 Fremgangsmåte for fremstilling av 1-(3-trialkylsilyl-fenyl)-2,2,2-trifluormetyletanonderivater NO964652D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23876894A 1994-05-05 1994-05-05
US08/382,949 US5554780A (en) 1994-05-05 1995-02-01 Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
PCT/US1995/004837 WO1995030678A1 (en) 1994-05-05 1995-04-18 Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives

Publications (2)

Publication Number Publication Date
NO964652L true NO964652L (no) 1996-11-04
NO964652D0 NO964652D0 (no) 1996-11-04

Family

ID=26931932

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964652A NO964652D0 (no) 1994-05-05 1996-11-04 Fremgangsmåte for fremstilling av 1-(3-trialkylsilyl-fenyl)-2,2,2-trifluormetyletanonderivater

Country Status (18)

Country Link
US (1) US5554780A (no)
EP (1) EP0758336B1 (no)
JP (1) JPH09512819A (no)
CN (1) CN1047176C (no)
AT (1) ATE182151T1 (no)
AU (1) AU681965B2 (no)
CA (1) CA2188761C (no)
DE (1) DE69510787T2 (no)
DK (1) DK0758336T3 (no)
ES (1) ES2138734T3 (no)
FI (1) FI964429L (no)
GR (1) GR3031283T3 (no)
HU (1) HU215133B (no)
IL (1) IL113605A (no)
NO (1) NO964652D0 (no)
NZ (1) NZ284696A (no)
TW (1) TW314521B (no)
WO (1) WO1995030678A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0749972A1 (en) * 1995-06-21 1996-12-27 Merrell Pharmaceuticals Inc. A process for preparing 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
ATE523199T1 (de) * 2004-11-02 2011-09-15 Univ Northwestern Pyridazinverbindungen und verfahren
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CN106045836B (zh) * 2016-06-30 2018-04-13 福州大学 一种铜催化合成芳烃或杂环三氟甲基酮的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536265A (en) * 1984-04-19 1985-08-20 Loctite Corporation Siloxane polyphotoinitiators of the substituted acetophenone type
SU1576526A1 (ru) * 1988-09-01 1990-07-07 Дальневосточный политехнический институт им.В.В.Куйбышева Способ получени N, N-диметиланилино- @ -трифторметилкетона
EP0403713A1 (en) * 1989-06-22 1990-12-27 Merrell Dow Pharmaceuticals Inc. Novel acetylcholinesterase inhibitors

Also Published As

Publication number Publication date
TW314521B (no) 1997-09-01
HU215133B (hu) 1998-09-28
HU9603050D0 (en) 1997-01-28
CN1047176C (zh) 1999-12-08
EP0758336A1 (en) 1997-02-19
US5554780A (en) 1996-09-10
IL113605A0 (en) 1995-08-31
JPH09512819A (ja) 1997-12-22
IL113605A (en) 1999-08-17
CN1147256A (zh) 1997-04-09
DE69510787T2 (de) 1999-11-11
FI964429A0 (fi) 1996-11-04
FI964429A7 (fi) 1996-11-04
DK0758336T3 (da) 1999-11-29
EP0758336B1 (en) 1999-07-14
ES2138734T3 (es) 2000-01-16
NZ284696A (en) 1997-12-19
WO1995030678A1 (en) 1995-11-16
FI964429L (fi) 1996-11-04
DE69510787D1 (de) 1999-08-19
CA2188761C (en) 1999-11-16
HUT75866A (en) 1997-05-28
CA2188761A1 (en) 1995-11-16
NO964652D0 (no) 1996-11-04
AU681965B2 (en) 1997-09-11
ATE182151T1 (de) 1999-07-15
GR3031283T3 (en) 1999-12-31
AU2390595A (en) 1995-11-29

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