NO970261D0 - Fremgangsmåte ved fremstilling av et dikarboksylsyre-diklorid - Google Patents

Fremgangsmåte ved fremstilling av et dikarboksylsyre-diklorid

Info

Publication number: NO970261D0
Authority: NO; Norway
Prior art keywords: preparation; acid dichloride; dicarboxylic acid; triiodo; amino
Prior art date: 1995-05-23

Application number

NO970261A

Other languages

English (en)

Other versions

NO313696B1 (no

NO970261L (no

Inventor

Marina Mauro

Carlo Felice Viscardi

Massimo Gagna

Original Assignee

Fructamine Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-23

Filing date

1997-01-21

Publication date

1997-01-21

1995-05-23 Priority claimed from ITMI951044A external-priority patent/IT1274546B/it

1995-08-04 Priority claimed from IT95RM000550 external-priority patent/IT1281320B1/it

1997-01-21 Application filed by Fructamine Spa filed Critical Fructamine Spa

1997-01-21 Publication of NO970261D0 publication Critical patent/NO970261D0/no

1997-05-02 Publication of NO970261L publication Critical patent/NO970261L/no

2002-11-18 Publication of NO313696B1 publication Critical patent/NO313696B1/no

Links

238000000034 method Methods 0.000 title abstract 2
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
DKPFZGUDAPQIHT-UHFFFAOYSA-N butyl acetate Chemical compound CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 abstract 1
FBJVWRITWDYUAC-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarbonyl chloride Chemical compound NC1=C(I)C(C(Cl)=O)=C(I)C(C(Cl)=O)=C1I FBJVWRITWDYUAC-UHFFFAOYSA-N 0.000 abstract 1
JEZJSNULLBSYHV-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid Chemical compound NC1=C(I)C(C(O)=O)=C(I)C(C(O)=O)=C1I JEZJSNULLBSYHV-UHFFFAOYSA-N 0.000 abstract 1
150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
230000003197 catalytic effect Effects 0.000 abstract 1
SBZXBUIDTXKZTM-UHFFFAOYSA-N diglyme Chemical compound COCCOCCOC SBZXBUIDTXKZTM-UHFFFAOYSA-N 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
150000002430 hydrocarbons Chemical class 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
150000003512 tertiary amines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/10—Compounds containing sulfur atoms doubly-bound to nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO19970261A 1995-05-23 1997-01-21 Fremgangsmåte ved fremstilling av et dikarboksylsyre-diklorid NO313696B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
ITMI951044A IT1274546B (it)	1995-05-23	1995-05-23	Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico
IT95RM000550 IT1281320B1 (it)	1995-08-04	1995-08-04	Procedimento di preparazione di dicloruro dell'acido 5-ammino-2,4,6- triiodo-1,3-benzendicarbossilico per reazione dell'acido
PCT/EP1996/002103 WO1996037459A1 (en)	1995-05-23	1996-05-17	Process for the preparation of a dicarboxylic acid dichloride

Publications (3)

Publication Number	Publication Date
NO970261D0 true NO970261D0 (no)	1997-01-21
NO970261L NO970261L (no)	1997-05-02
NO313696B1 NO313696B1 (no)	2002-11-18

Family

ID=26331277

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19970261A NO313696B1 (no)	1995-05-23	1997-01-21	Fremgangsmåte ved fremstilling av et dikarboksylsyre-diklorid

Country Status (22)

Country	Link
US (1)	US5616795A (no)
EP (1)	EP0773924B1 (no)
JP (1)	JP4012566B2 (no)
KR (1)	KR100255914B1 (no)
CN (1)	CN1157367C (no)
AT (1)	ATE176663T1 (no)
AU (1)	AU702895B2 (no)
BR (1)	BR9606488A (no)
CA (1)	CA2195636C (no)
CZ (1)	CZ290345B6 (no)
DE (2)	DE69601525T2 (no)
DK (1)	DK0773924T3 (no)
ES (1)	ES2103252T3 (no)
GR (1)	GR970300027T1 (no)
HU (1)	HU216548B (no)
IL (1)	IL118359A (no)
MX (1)	MX9700548A (no)
NO (1)	NO313696B1 (no)
PL (1)	PL182447B1 (no)
SI (1)	SI9620012A (no)
SK (1)	SK8797A3 (no)
WO (1)	WO1996037459A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1271107B (it) *	1994-11-29	1997-05-26	Zambon Spa	Processo per la preparazione di un intermedio utile nella sintesi di composti organici
IT1292037B1 (it) *	1997-05-30	1999-01-25	Bracco Spa	Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
WO2007073202A1 (en)	2005-12-19	2007-06-28	Ge Healthcare As	Purification process of iodixanol
GB0717189D0 (en) *	2007-09-04	2007-10-17	Syngenta Participations Ag	Novel processes and compounds
EP2240432B1 (en)	2008-01-14	2012-07-04	Mallinckrodt LLC	Process for the preparation of iosimenol
EP2230227A1 (en) *	2009-03-20	2010-09-22	Bracco Imaging S.p.A	Process for the preparation of triiodinated carboxylic aromatic derivatives
EP2243767A1 (en) *	2009-04-21	2010-10-27	Bracco Imaging S.p.A	Process for the iodination of aromatic compounds
US7999134B2 (en)	2009-07-21	2011-08-16	Ge Healthcare As	Crystallization of iodixanol using milling
US7999135B2 (en)	2009-07-21	2011-08-16	Ge Healthcare As	Crystallization of iodixanol using ultrasound
US8766002B2 (en)	2009-11-26	2014-07-01	Imax Diagnostic Imaging Holding Limited	Preparation and purification of iodixanol
EP2394984A1 (en)	2010-06-10	2011-12-14	Bracco Imaging S.p.A	Process for the iodination of phenolic derivatives
HUE040143T2 (hu)	2012-12-11	2019-02-28	Bracco Imaging Spa	Folyamatos eljárás (S)-2-acetiloxipropionsav elõállítására
PT3369724T (pt)	2013-11-05	2021-02-10	Bracco Imaging Spa	Processo para a preparação de iopamidol
EP3154928B1 (en)	2014-06-10	2020-03-04	Bracco Imaging S.p.A	Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof
CN104230731B (zh) *	2014-09-24	2016-01-20	武汉理工大学	造影剂中间体三碘异酞酰氯的制备方法
WO2018104228A1 (en)	2016-12-05	2018-06-14	Bracco Imaging Spa	Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH608189A5 (no) *	1974-12-13	1978-12-29	Savac Ag
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
IT1207226B (it) *	1979-08-09	1989-05-17	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
US4396598A (en) *	1982-01-11	1983-08-02	Mallinckrodt, Inc.	Triiodoisophthalamide X-ray contrast agent
FR2541676A1 (fr) *	1983-02-25	1984-08-31	Guerbet Sa	Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
US5191120A (en) *	1989-12-13	1993-03-02	Mallinckrodt Medical, Inc.	Process for preparing nonionic X-ray contrast agents
US5075502A (en) *	1989-12-13	1991-12-24	Mallinckrodt, Inc.	Nonionic x-ray contrast agents, compositions and methods
IT1271107B (it) *	1994-11-29	1997-05-26	Zambon Spa	Processo per la preparazione di un intermedio utile nella sintesi di composti organici

1996
- 1996-05-17 HU HU9700188A patent/HU216548B/hu unknown
- 1996-05-17 KR KR1019970700402A patent/KR100255914B1/ko not_active Expired - Lifetime
- 1996-05-17 ES ES96916098T patent/ES2103252T3/es not_active Expired - Lifetime
- 1996-05-17 AT AT96916098T patent/ATE176663T1/de active
- 1996-05-17 SI SI9620012A patent/SI9620012A/sl unknown
- 1996-05-17 AU AU58978/96A patent/AU702895B2/en not_active Expired
- 1996-05-17 US US08/650,094 patent/US5616795A/en not_active Expired - Lifetime
- 1996-05-17 BR BR9606488A patent/BR9606488A/pt not_active Application Discontinuation
- 1996-05-17 CN CNB961905271A patent/CN1157367C/zh not_active Expired - Lifetime
- 1996-05-17 EP EP96916098A patent/EP0773924B1/en not_active Expired - Lifetime
- 1996-05-17 PL PL96318311A patent/PL182447B1/pl unknown
- 1996-05-17 DE DE69601525T patent/DE69601525T2/de not_active Expired - Lifetime
- 1996-05-17 JP JP53534596A patent/JP4012566B2/ja not_active Expired - Lifetime
- 1996-05-17 MX MX9700548A patent/MX9700548A/es unknown
- 1996-05-17 CZ CZ1997187A patent/CZ290345B6/cs not_active IP Right Cessation
- 1996-05-17 DK DK96916098T patent/DK0773924T3/da active
- 1996-05-17 SK SK87-97A patent/SK8797A3/sk unknown
- 1996-05-17 CA CA002195636A patent/CA2195636C/en not_active Expired - Lifetime
- 1996-05-17 DE DE0773924T patent/DE773924T1/de active Pending
- 1996-05-17 WO PCT/EP1996/002103 patent/WO1996037459A1/en not_active Ceased
- 1996-05-22 IL IL11835996A patent/IL118359A/xx not_active IP Right Cessation
1997
- 1997-01-21 NO NO19970261A patent/NO313696B1/no not_active IP Right Cessation
- 1997-09-30 GR GR970300027T patent/GR970300027T1/el unknown

Also Published As

Publication number	Publication date
PL318311A1 (en)	1997-06-09
CZ18797A3 (en)	1997-07-16
KR100255914B1 (ko)	2000-05-01
IL118359A0 (en)	1996-09-12
PL182447B1 (pl)	2002-01-31
HUP9700188A1 (hu)	1998-01-28
GR970300027T1 (en)	1997-09-30
CZ290345B6 (cs)	2002-07-17
ES2103252T3 (es)	1999-04-01
AU5897896A (en)	1996-12-11
CA2195636A1 (en)	1996-11-28
EP0773924B1 (en)	1999-02-10
ATE176663T1 (de)	1999-02-15
WO1996037459A1 (en)	1996-11-28
SI9620012A (en)	1997-06-30
DK0773924T3 (da)	1999-09-20
NO313696B1 (no)	2002-11-18
IL118359A (en)	2000-10-31
MX9700548A (es)	1997-05-31
DE773924T1 (de)	1997-12-18
JPH10508874A (ja)	1998-09-02
CN1157367C (zh)	2004-07-14
NO970261L (no)	1997-05-02
SK8797A3 (en)	1997-08-06
DE69601525D1 (de)	1999-03-25
CN1154689A (zh)	1997-07-16
US5616795A (en)	1997-04-01
DE69601525T2 (de)	1999-06-24
HUP9700188A3 (en)	1998-03-02
ES2103252T1 (es)	1997-09-16
JP4012566B2 (ja)	2007-11-21
CA2195636C (en)	2007-10-30
HU216548B (hu)	1999-07-28
BR9606488A (pt)	1997-11-25
AU702895B2 (en)	1999-03-11
EP0773924A1 (en)	1997-05-21

Legal Events

Date	Code	Title	Description
2016-05-23	MK1K	Patent expired

Publication	Publication Date	Title
NO970261D0 (no)	1997-01-21	Fremgangsmåte ved fremstilling av et dikarboksylsyre-diklorid
BR9809238A (pt)	2000-06-27	Processo para a preparação de sais de ácido carboxìlico e catalisadores úteis em tal processo
NO983563D0 (no)	1998-08-03	Fremgangsmåte ved fremstilling av 5-amino-2,4,6-trijod-1,3-benzendikarboksylsyre-derivater
NO970262L (no)	1997-03-24	Fremgangsmåte ved fremstilling av et dikarboksylsyre-diklorid
HUP9700189A3 (en)	1998-03-02	Process for producing 5-amino-2,4,6-triiode-1,3-benzenedicarboxylic acid
FI972261L (fi)	1997-05-28	Menetelmä 5-amino-2,4,6-trijodi-isoftaalihappodikloridin valmistamiseksi klooraamalla vastaavaa happoa tertiäärisen amiinisuolan tai kvaternäärisen ammoniumsuolan läsnäollessa
HUP9801142A3 (en)	1998-09-28	Process for the preparation of 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst
IT1274546B (it)	1997-07-17	Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico
MX9700550A (es)	1997-05-31	Procedimiento para la preparacion de un dicloruro de acido dicarboxilico.
TH21704A (th)	1996-11-13	เพพไทด์ชนิดใหม่ที่มีผลปรับภูมิคุ้มกัน
IT1281320B1 (it)	1998-02-18	Procedimento di preparazione di dicloruro dell'acido 5-ammino-2,4,6- triiodo-1,3-benzendicarbossilico per reazione dell'acido
MX9706960A (es)	1998-07-31	Proceso para sintetizar acidos benzoicos.