NO970514L - Bakteriell produksjon av hydrofobiske polypeptider - Google Patents

Bakteriell produksjon av hydrofobiske polypeptider

Info

Publication number
NO970514L
NO970514L NO970514A NO970514A NO970514L NO 970514 L NO970514 L NO 970514L NO 970514 A NO970514 A NO 970514A NO 970514 A NO970514 A NO 970514A NO 970514 L NO970514 L NO 970514L
Authority
NO
Norway
Prior art keywords
bacterial production
production
hydrophobic polypeptides
cation concentration
polypeptides
Prior art date
Application number
NO970514A
Other languages
English (en)
Other versions
NO324529B1 (no
NO970514D0 (no
Inventor
Glenn Dorin
Patrick J Mcalary
Kathleen M Wong
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of NO970514D0 publication Critical patent/NO970514D0/no
Publication of NO970514L publication Critical patent/NO970514L/no
Publication of NO324529B1 publication Critical patent/NO324529B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19970514A 1995-06-06 1997-02-05 Fremgangsmate for a fremstille interferon-beta i en Escherischia coli-vertscelle. NO324529B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/477,310 US5814485A (en) 1995-06-06 1995-06-06 Production of interferon-β (IFN-β) in E. coli
PCT/US1996/009155 WO1996039523A2 (en) 1995-06-06 1996-06-05 Bacterial production of hydrophobic polypeptides

Publications (3)

Publication Number Publication Date
NO970514D0 NO970514D0 (no) 1997-02-05
NO970514L true NO970514L (no) 1997-03-17
NO324529B1 NO324529B1 (no) 2007-11-12

Family

ID=23895395

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19970514A NO324529B1 (no) 1995-06-06 1997-02-05 Fremgangsmate for a fremstille interferon-beta i en Escherischia coli-vertscelle.

Country Status (17)

Country Link
US (1) US5814485A (no)
EP (1) EP0778893B1 (no)
JP (3) JP4131554B2 (no)
AT (1) ATE449175T1 (no)
AU (1) AU6154996A (no)
BR (1) BR9606491A (no)
CA (1) CA2195799C (no)
DE (1) DE69638077D1 (no)
FI (1) FI970445A7 (no)
IL (1) IL120009A0 (no)
IN (1) IN190514B (no)
MX (1) MX9700818A (no)
MY (1) MY118492A (no)
NO (1) NO324529B1 (no)
NZ (1) NZ310710A (no)
TW (1) TW494138B (no)
WO (1) WO1996039523A2 (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997048808A1 (en) * 1996-06-19 1997-12-24 Chiron Corporation Bacterial production of interferon-beta using low levels of sodium and potassium ions
US6514729B1 (en) 1999-05-12 2003-02-04 Xencor, Inc. Recombinant interferon-beta muteins
RU2180687C1 (ru) * 2000-07-05 2002-03-20 Общество с ограниченной ответственностью "Биотех" Штамм дрожжей pichia pastoris - продуцент фибробластного интерферона человека, рекомбинантная плазмидная днк phif и способ ее конструирования
US7544354B2 (en) * 2000-10-27 2009-06-09 Novartis Vaccines And Diagnostics Methods of protein purification and recovery
AU2002236477A1 (en) * 2000-11-21 2002-06-03 The Texas A & M University System Fgf-affinity chromatography
CN1596123A (zh) * 2000-11-29 2005-03-16 森永乳业株式会社 干扰素治疗效果增强剂
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
UY27373A1 (es) * 2001-07-09 2003-02-28 Schering Ag Formulaciones de interferón beta-humano
CA2498319A1 (en) * 2002-09-09 2004-03-18 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
WO2005016371A1 (en) 2003-07-11 2005-02-24 Schering Aktiengesellschaft IMPROVED RECOMBINANT HUMAN INTERFERON-BETA-1b POLYPEPTIDES
AU2004298781B2 (en) * 2003-12-11 2010-04-01 Ares Trading S.A. Stabilized interferon liquid formulations
CN103755800B (zh) 2004-02-02 2016-02-24 Ambrx公司 经修饰的人类生长激素多肽与其用途
CN101238214A (zh) * 2005-05-19 2008-08-06 拜尔先灵制药股份公司 使用改进的调节表达系统治疗疾病
US20080076729A1 (en) * 2005-05-19 2008-03-27 Schering Aktiengesellachaft Interferon-beta gene therapy using an improved, regulated expression system
US20070179113A1 (en) * 2005-05-19 2007-08-02 Schering Aktiengesellachaft GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
GT200600210A (es) * 2005-05-19 2007-01-03 Schering Ag Terapia genica de interferon-beta usdando un sistema mejorado de expresion regulada
WO2007110231A2 (en) * 2006-03-28 2007-10-04 Nautilus Biotech, S.A. MODIFIED INTERFERON-β (IFN-β) POLYPEPTIDES
AU2007351813B2 (en) 2006-10-31 2013-10-10 East Carolina University Fusion proteins comprising an anti-inflammatory cytokine and an antigen for treatment of immune disorders
WO2008125222A2 (en) * 2007-04-11 2008-10-23 Bayer Schering Pharma Aktiengesellschaft New modulation molecules for an improved regulated expression system
KR20100019467A (ko) 2007-05-02 2010-02-18 암브룩스, 인코포레이티드 변형된 인터페론 베타 폴리펩티드 및 그의 용도
US8273561B2 (en) * 2007-10-05 2012-09-25 Nuron Biotech, Inc. High pressure treatment of aggregated interferons
BRPI0821029A2 (pt) * 2007-12-20 2015-06-16 Merck Serono Sa Fomulações de peg-interferon-beta
NZ602170A (en) 2008-02-08 2014-03-28 Ambrx Inc Modified leptin polypeptides and their uses
KR20090124204A (ko) * 2008-05-29 2009-12-03 (주)바이오큐어팜 아미노 말단의 메티오닌이 제거된 재조합 사람 변이인터페론-베타 단백질을 생산하는 재조합 대장균 및 이의제조방법
US20120082644A1 (en) 2009-03-31 2012-04-05 Mannie Mark D Cytokines and neuroantigens for treatment of immune disorders
WO2011092367A1 (es) * 2010-02-01 2011-08-04 Digna Biotech,S.L. Procedimiento para la producción de interferón alfa 5
WO2011109556A2 (en) * 2010-03-04 2011-09-09 Pfenex Inc. Method for producing soluble recombinant interferon protein without denaturing
RU2473696C1 (ru) * 2011-07-14 2013-01-27 Закрытое акционерное общество "ГЕНЕРИУМ" ПРОМЫШЛЕННЫЙ СПОСОБ ПОЛУЧЕНИЯ И ОЧИСТКИ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА β-1b ЧЕЛОВЕКА ИЗ ТЕЛЕЦ ВКЛЮЧЕНИЯ
JP6363326B2 (ja) * 2013-03-11 2018-07-25 株式会社コーセー 酵母・細菌共通培養方法およびこれに用いる酵母・細菌共通培養培地
JP7151049B2 (ja) * 2018-03-30 2022-10-12 三井化学株式会社 微生物を増殖させる方法
JP2023159758A (ja) * 2022-04-20 2023-11-01 東ソー株式会社 遺伝子組換え大腸菌を用いたタンパク質の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499188A (en) * 1982-05-05 1985-02-12 Cetus Corporation Bacterial production of heterologous polypeptides under the control of a repressible promoter-operator
FI82266C (fi) * 1982-10-19 1991-02-11 Cetus Corp Foerfarande foer framstaellning av il-2 -mutein.
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
US4656132A (en) * 1984-03-28 1987-04-07 Cetus Corporation Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
JPH0755152B2 (ja) * 1986-06-02 1995-06-14 日本化薬株式会社 組換え遺伝子産物の製法及び培地

Also Published As

Publication number Publication date
CA2195799A1 (en) 1996-12-12
JP4131554B2 (ja) 2008-08-13
NO324529B1 (no) 2007-11-12
WO1996039523A3 (en) 1997-01-30
NO970514D0 (no) 1997-02-05
WO1996039523A2 (en) 1996-12-12
IN190514B (no) 2003-08-02
FI970445L (fi) 1997-03-26
JPH11501820A (ja) 1999-02-16
AU6154996A (en) 1996-12-24
JP4317890B2 (ja) 2009-08-19
BR9606491A (pt) 1997-09-02
MY118492A (en) 2004-11-30
TW494138B (en) 2002-07-11
EP0778893B1 (en) 2009-11-18
NZ310710A (en) 1999-01-28
US5814485A (en) 1998-09-29
CA2195799C (en) 2010-02-09
FI970445A7 (fi) 1997-03-26
ATE449175T1 (de) 2009-12-15
MX9700818A (es) 1997-05-31
JP2008283988A (ja) 2008-11-27
JP2008086331A (ja) 2008-04-17
DE69638077D1 (de) 2009-12-31
EP0778893A2 (en) 1997-06-18
FI970445A0 (fi) 1997-02-03
IL120009A0 (en) 1997-04-15

Similar Documents

Publication Publication Date Title
NO970514D0 (no) Bakteriell produksjon av hydrofobiske polypeptider
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
NO900770D0 (no) Produksjon av glykoseoksidase i rekombinante systemer.
YU45871B (sh) Polipeptid sa humanim imunointerferonskim (ifn-gama) svojstvima
ES8706443A1 (es) Un procedimiento para preparar una solucion parenteral de activador de plasminogeno de tejido (t-pa)
EP0724632A4 (en) STEM CELL PROLIFERATION FACTOR
ATE310098T1 (de) Dna kodierend für glutaminsäure-gesteuerte chloridkanäle
EP1085083A4 (en) CULTURAL MEDIUM FOR CULTIVATING ANIMAL CELLS AND METHOD FOR PRODUCING PROTEINS BY THE USE THEREOF
FI925988A0 (fi) Foerfarande foer framstaellning av b-laktamer
SE8801701D0 (sv) Production technology based on enzymic method
EP0726944A4 (en) GLYCOSYLATED AND NON-GLYCOSYLATED PROTEINS, BACTERICIDES AND INCREASING PERMEABILITY, AND PROCESS FOR PRODUCING THE SAME
FR2665168B1 (fr) Composition comportant un succinoglycane.
PT935652E (pt) Produtos de factor de crescimento de queratinocitos-2
NO20052209D0 (no) Fremgansmate for fremstilling av nytt og naturlig avermektin
EP0160486A3 (en) Monoclonal antibodies
RU94043769A (ru) Способ повышения продукции протеина с, способ повышения уровня его модификации
ES2052513T3 (es) Nuevos polipeptidos, su fabricacion y empleo.
ATE432292T1 (de) Antitumorantikörper, proteine und deren verwendung
ATE210460T1 (de) Zusammensetzungen, welche adp-ribosyltransferase- aktivität aufweisen und methoden für ihre herstellung und die verwendung derselben
AU8011498A (en) Novel ppgpp synthetase and expression systems for improved production of proteinof interest
ES8707563A1 (es) Un procedimiento para purificar urocinasa
AU2099800A (en) Production of proteins
DK143984A (da) Nitrogenkilde til organismer
DE59610098D1 (de) Protein mit anti-tumorwirkung
IT1178489B (it) Vettore clonante, procedimento per la sua costruzione e procedimento di concentrazione e di purificazione di proteine prodotte, formate dal vettore clonante

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees