ATE310098T1 - Dna kodierend für glutaminsäure-gesteuerte chloridkanäle - Google Patents

Dna kodierend für glutaminsäure-gesteuerte chloridkanäle

Info

Publication number: ATE310098T1
Authority: AT; Austria
Prior art keywords: host cells; chloride channels; glutamic acid; dna coding; recombinant host
Prior art date: 1995-05-05

Application number

AT96913285T

Other languages

English (en)

Inventor

Doris F Cully

Joseph P Arena

Philip S Paress

Ken K Liu

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-05

Filing date

1996-05-01

Publication date

2005-12-15

1996-05-01 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE310098T1 publication Critical patent/ATE310098T1/de

Links

108010062745 Chloride Channels Proteins 0.000 title 1
102000011045 Chloride Channels Human genes 0.000 title 1
102000005962 receptors Human genes 0.000 abstract 3
108020003175 receptors Proteins 0.000 abstract 3
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 2
102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
229930195712 glutamate Natural products 0.000 abstract 2
239000005660 Abamectin Substances 0.000 abstract 1
108091006146 Channels Proteins 0.000 abstract 1
108050006905 Glutamate-Gated Chloride Channel Proteins 0.000 abstract 1
230000000895 acaricidal effect Effects 0.000 abstract 1
230000002141 anti-parasite Effects 0.000 abstract 1
239000003096 antiparasitic agent Substances 0.000 abstract 1
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
239000002299 complementary DNA Substances 0.000 abstract 1
239000013057 ectoparasiticide Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000002917 insecticide Substances 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Cell Biology (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

AT96913285T 1995-05-05 1996-05-01 Dna kodierend für glutaminsäure-gesteuerte chloridkanäle ATE310098T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/435,933 US5693492A (en)	1995-05-05	1995-05-05	DNA encoding glutamate gated chloride channels
PCT/US1996/006035 WO1996034940A1 (en)	1995-05-05	1996-05-01	Dna encoding glutamate gated chloride channels

Publications (1)

Publication Number	Publication Date
ATE310098T1 true ATE310098T1 (de)	2005-12-15

Family

ID=23730421

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96913285T ATE310098T1 (de)	1995-05-05	1996-05-01	Dna kodierend für glutaminsäure-gesteuerte chloridkanäle

Country Status (8)

Country	Link
US (1)	US5693492A (de)
EP (1)	EP0871703B1 (de)
JP (1)	JP3862278B2 (de)
AT (1)	ATE310098T1 (de)
CA (1)	CA2220116C (de)
DE (1)	DE69635455T2 (de)
ES (1)	ES2250989T3 (de)
WO (1)	WO1996034940A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5527703A (en) *	1994-05-25	1996-06-18	Merck & Co., Inc.	DNA encoding glutamate gated chloride channels
US6358701B1 (en) *	1997-08-11	2002-03-19	Merck & Co., Inc.	DNA molecules encoding Ctenocephalides felis glutamate gated chloride channels
DE19819829A1 (de) *	1998-05-04	1999-11-11	Bayer Ag	Nukleinsäuren, die für Acetylcholinrezeptor-Untereinheiten von Insekten kodieren
CA2388162A1 (en) *	1999-10-22	2001-05-03	Merck & Co., Inc.	Dna molecules encoding l-glutamate-gated chloride channels from schistocerca americana
WO2001064705A1 (en) *	2000-03-02	2001-09-07	Merck & Co., Inc.	Dna molecules encoding a glutamate-gated chloride channel in drosophila melanogaster
DE10013619A1 (de) *	2000-03-18	2001-10-11	Bayer Ag	Ligandengesteuerte Anionenkanäle von Insekten
ES2274878T3 (es)	2000-03-31	2007-06-01	Merial Limited	Moleculas de adn que codifican canales ionicos sensibles al ligado de dermacentor variabilis.
EP1294751B1 (de) *	2000-03-31	2014-03-05	Merial Limited	Gaba-abhängige chloridkanäle aus dermacentor variabilis
PT1272503E (pt) *	2000-03-31	2011-05-02	Merial Ltd	Mol?culas de adn que codificam canais de cloro activados pelo l-glutamato de rhipicephalus sanguineus
US7267964B2 (en) *	2000-03-31	2007-09-11	Merial Limited	DNA molecules encoding ligand gated ion channels from Dermacentor variabilis
US6329174B1 (en)	2000-06-13	2001-12-11	Aventis Cropscience Sa	Nucleic acid encoding lepidoteran glutamate-gated chloride channel
AU2005293752A1 (en) *	2004-10-13	2006-04-20	Ablynx N.V.	Single domain camelide anti-amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as Alzheimer's disease
RU2464276C2 (ru)	2005-05-18	2012-10-20	Аблинкс Н.В.	Улучшенные нанотела против фактора некроза опухоли-альфа
DK2444424T3 (en)	2005-05-20	2018-12-03	Ablynx Nv	IMPROVED NANOL BODIES (TM) FOR TREATING AGGREGATED MEDICINAL DISORDERS
AU2007336242B2 (en)	2006-12-19	2012-08-30	Ablynx N.V.	Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
AU2007336243B2 (en)	2006-12-19	2012-07-26	Ablynx N.V.	Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders
WO2009124931A2 (en)	2008-04-07	2009-10-15	Ablynx Nv	Amino acid sequences directed against the notch pathways and uses thereof
DK2370465T3 (da)	2008-12-19	2019-05-06	Ablynx Nv	Genetisk immunisering til fremstilling af immunoglobuliner mod celleassocierede antigener, såsom p2x7, cxcr7 eller cxcr4
AU2010233658B2 (en)	2009-04-10	2013-11-28	Ablynx Nv	Improved amino acid sequences directed against IL-6R and polypeptides comprising the same for the treatment of IL-6R related diseases and disorders
EP2438087B1 (de)	2009-06-05	2017-05-10	Ablynx N.V.	Trivalente anti-humanes respiratory syncytial virus (hrsv) nanobody konstrukte zur präventionund/oder behandlung von infektionen des atmungstraktes
WO2011064382A1 (en)	2009-11-30	2011-06-03	Ablynx N.V.	Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
WO2011083140A1 (en)	2010-01-08	2011-07-14	Ablynx Nv	Immunoglobulin single variable domain directed against human cxcr4
NL2013661B1 (en)	2014-10-21	2016-10-05	Ablynx Nv	KV1.3 Binding immunoglobulins.
CA3043515A1 (en)	2016-11-16	2018-05-24	Ablynx Nv	T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
US20200392512A1 (en)	2018-02-26	2020-12-17	Ablynx N.V.	Nucleotide sequences encoding peptide linkers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5385831A (en) *	1990-12-12	1995-01-31	Zymogenetics, Inc.	Method for producing a mammalian G protein coupled glutamate receptor
NZ240921A (en) *	1990-12-12	1994-06-27	Zymogenetics Inc	G protein coupled glutamate receptor (neurotransmitters), recombinant production
WO1992019717A1 (en) *	1991-04-02	1992-11-12	Baylor College Of Medicine	A high-affinity human glutamate/aspartate uptake system
GB9112504D0 (en) *	1991-06-11	1991-07-31	Merck Sharp & Dohme	Cell line
WO1993007161A1 (en) *	1991-10-04	1993-04-15	Cornell Research Foundation, Inc.	Molecular cloning and transformation of cyclodiene resistance
US5527703A (en) *	1994-05-25	1996-06-18	Merck & Co., Inc.	DNA encoding glutamate gated chloride channels

1995
- 1995-05-05 US US08/435,933 patent/US5693492A/en not_active Expired - Lifetime
1996
- 1996-05-01 JP JP53343596A patent/JP3862278B2/ja not_active Expired - Lifetime
- 1996-05-01 DE DE69635455T patent/DE69635455T2/de not_active Expired - Lifetime
- 1996-05-01 AT AT96913285T patent/ATE310098T1/de not_active IP Right Cessation
- 1996-05-01 ES ES96913285T patent/ES2250989T3/es not_active Expired - Lifetime
- 1996-05-01 EP EP96913285A patent/EP0871703B1/de not_active Expired - Lifetime
- 1996-05-01 WO PCT/US1996/006035 patent/WO1996034940A1/en not_active Ceased
- 1996-05-01 CA CA2220116A patent/CA2220116C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH11506906A (ja)	1999-06-22
ES2250989T3 (es)	2006-04-16
DE69635455D1 (de)	2005-12-22
EP0871703B1 (de)	2005-11-16
WO1996034940A1 (en)	1996-11-07
EP0871703A4 (de)	2000-03-01
EP0871703A1 (de)	1998-10-21
US5693492A (en)	1997-12-02
CA2220116C (en)	2011-04-19
JP3862278B2 (ja)	2006-12-27
DE69635455T2 (de)	2006-08-03
CA2220116A1 (en)	1996-11-07

Legal Events

Date	Code	Title	Description
2006-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE310098T1 (de)	2005-12-15	Dna kodierend für glutaminsäure-gesteuerte chloridkanäle
HUP0101136A2 (hu)	2001-08-28	Fehérjeexpresszió baculovírus-vektort alkalmazó expressziós rendszerben
DE69633825D1 (de)	2004-12-16	Modifiziertes enzym mit lipolytischer aktivität
DE69638032D1 (de)	2009-11-05	Modifiziertes bacillus thuringiensis gen zur kontrolle von lepidoptera in pflanzen
BR9508981A (pt)	1997-12-30	Mutantes de subtilisina isentos de cálcio
ATE389666T1 (de)	2008-04-15	Hohe expressionsrate von proteinen
DE69638077D1 (de)	2009-12-31	Bakterielle Produktion von Interferon-beta Polypeptiden
AR053931A2 (es)	2007-05-23	Secuencia de adn que codifica una proteina de a. thaliana que posee actividad de delta -5,7-esterol, delta-7-reductasa, proteina delta-7red
ATE283368T1 (de)	2004-12-15	Für die glutamatabhängigen chloridkanäle kodierende dna
EP0967283A4 (de)	2004-06-09	Gene, die für proteine mit transglykolysierungsaktivität kodieren.
DE69736389D1 (de)	2006-09-07	Proteine mit zellulase-aktivitäten und prozess für ihre herstellung
WO2000063415A8 (en)	2001-01-18	Dna encoding the human vanilloid receptor vr1
ATE372375T1 (de)	2007-09-15	Für den bradykinin-b1-rezeptor kodierende dna
ATE384739T1 (de)	2008-02-15	Für den menschlichen vanilloid-rezeptor vr3 kodierende dns
DE60129688D1 (de)	2007-09-13	Die menschliche beta-1a-untereinheit des potential-abhängigen natriumkanals und deren verwendungen
DE60033297D1 (de)	2007-03-22	Für die humane untereinheit 5-ht3-c des serotoninrezeptors 5-ht3 kodierende dna
ATE202798T1 (de)	2001-07-15	D-aminosäure-oxidase kodierendes dns-fragment
ES2012283A6 (es)	1990-03-01	Procedimiento de obtencion de una proteina de endotoxina de efecto insecticida.
ATE266094T1 (de)	2004-05-15	Produktion des proteins ingap mit hoher expressionsrate
DE59611293D1 (de)	2005-12-15	Protein mit dnase-aktivität
DE69127743D1 (de)	1997-10-30	Für ein Protein, das sich mit dem Enhancer des Alpha-Fetoprotein verbindet, kodierende DNS
KR950704352A (ko)	1995-11-20	테라포시데 아포노펠마로부터의 칼슘 통로 차단 폴리펩티드(calcium channel blocking polypeptides from theraphosidae aphonopelma)
FI883775A7 (fi)	1988-08-15	Kloonatut streptokokkigeenit, jotka koodaavat proteiinia G, ja niiden käyttö proteiinia G tuottavien rekombinantti-mikro-organismien konstru oimiseksi.