ATE310098T1 - Dna kodierend für glutaminsäure-gesteuerte chloridkanäle - Google Patents

Dna kodierend für glutaminsäure-gesteuerte chloridkanäle

Info

Publication number: ATE310098T1
Authority: AT; Austria
Prior art keywords: host cells; chloride channels; glutamic acid; dna coding; recombinant host
Prior art date: 1995-05-05

Application number

AT96913285T

Other languages

English (en)

Inventor

Doris F Cully

Joseph P Arena

Philip S Paress

Ken K Liu

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-05

Filing date

1996-05-01

Publication date

2005-12-15

1996-05-01 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE310098T1 publication Critical patent/ATE310098T1/de

Links

108010062745 Chloride Channels Proteins 0.000 title 1
102000011045 Chloride Channels Human genes 0.000 title 1
102000005962 receptors Human genes 0.000 abstract 3
108020003175 receptors Proteins 0.000 abstract 3
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 2
102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
229930195712 glutamate Natural products 0.000 abstract 2
239000005660 Abamectin Substances 0.000 abstract 1
108091006146 Channels Proteins 0.000 abstract 1
108050006905 Glutamate-Gated Chloride Channel Proteins 0.000 abstract 1
230000000895 acaricidal effect Effects 0.000 abstract 1
230000002141 anti-parasite Effects 0.000 abstract 1
239000003096 antiparasitic agent Substances 0.000 abstract 1
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
239000002299 complementary DNA Substances 0.000 abstract 1
239000013057 ectoparasiticide Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000002917 insecticide Substances 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Cell Biology (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT96913285T 1995-05-05 1996-05-01 Dna kodierend für glutaminsäure-gesteuerte chloridkanäle ATE310098T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/435,933 US5693492A (en)	1995-05-05	1995-05-05	DNA encoding glutamate gated chloride channels
PCT/US1996/006035 WO1996034940A1 (en)	1995-05-05	1996-05-01	Dna encoding glutamate gated chloride channels

Publications (1)

Publication Number	Publication Date
ATE310098T1 true ATE310098T1 (de)	2005-12-15

Family

ID=23730421

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96913285T ATE310098T1 (de)	1995-05-05	1996-05-01	Dna kodierend für glutaminsäure-gesteuerte chloridkanäle

Country Status (8)

Country	Link
US (1)	US5693492A (de)
EP (1)	EP0871703B1 (de)
JP (1)	JP3862278B2 (de)
AT (1)	ATE310098T1 (de)
CA (1)	CA2220116C (de)
DE (1)	DE69635455T2 (de)
ES (1)	ES2250989T3 (de)
WO (1)	WO1996034940A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5527703A (en) *	1994-05-25	1996-06-18	Merck & Co., Inc.	DNA encoding glutamate gated chloride channels
US6358701B1 (en) *	1997-08-11	2002-03-19	Merck & Co., Inc.	DNA molecules encoding Ctenocephalides felis glutamate gated chloride channels
DE19819829A1 (de) *	1998-05-04	1999-11-11	Bayer Ag	Nukleinsäuren, die für Acetylcholinrezeptor-Untereinheiten von Insekten kodieren
CA2388162A1 (en) *	1999-10-22	2001-05-03	Merck & Co., Inc.	Dna molecules encoding l-glutamate-gated chloride channels from schistocerca americana
US7244586B2 (en) *	2000-03-02	2007-07-17	Merck & Co., Inc.	DNA molecules encoding ligand-gated ion channels from Drosophila melanogaster
DE10013619A1 (de) *	2000-03-18	2001-10-11	Bayer Ag	Ligandengesteuerte Anionenkanäle von Insekten
DE60144276D1 (de) *	2000-03-31	2011-05-05	Merial Ltd	Te chloridkanäle kodieren aus rhipicephalus sanguineus
WO2001074884A1 (en) *	2000-03-31	2001-10-11	Merck & Co., Inc.	Dermacentor variabilis gaba-gated chloride channels
DK1280821T3 (da)	2000-03-31	2007-02-05	Merial Ltd	DNA-molekyler der koder for ligand-gatede ionkanaler fra dermacentor variabilis
US7267964B2 (en) *	2000-03-31	2007-09-11	Merial Limited	DNA molecules encoding ligand gated ion channels from Dermacentor variabilis
US6329174B1 (en)	2000-06-13	2001-12-11	Aventis Cropscience Sa	Nucleic acid encoding lepidoteran glutamate-gated chloride channel
WO2006040153A2 (en) *	2004-10-13	2006-04-20	Ablynx N.V.	Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease
AU2006249144B2 (en)	2005-05-18	2011-11-17	Ablynx Nv	Improved NanobodiesTM against Tumor Necrosis Factor-alpha
MX2007014564A (es)	2005-05-20	2008-02-07	Ablynx Nv	Anticuerpos de vhh de dominio unico contra el factor de von willebrand.
CA2673331A1 (en)	2006-12-19	2008-06-26	Ablynx N.V.	Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
AU2007336243B2 (en)	2006-12-19	2012-07-26	Ablynx N.V.	Amino acid sequences directed against a metalloproteinase from the ADAM family and polypeptides comprising the same for the treatment of ADAM-related diseases and disorders
AU2009235467A1 (en)	2008-04-07	2009-10-15	Ablynx Nv	Single variable domains against the Notch pathways
AU2009329501B2 (en)	2008-12-19	2015-11-26	Ablynx N.V.	Genetic immunization for producing immunoglobulins against cell-associated antigens such as P2X7, CXCR7 or CXCR4
US8748581B2 (en)	2009-04-10	2014-06-10	Ablynx N.V.	Anti-IL-6R polypeptides and pharmaceutical compositions thereof
KR101852204B1 (ko)	2009-06-05	2018-04-26	아블린쓰 엔.브이.	기도 감염의 예방 및/또는 치료를 위한 일가, 이가 및 삼가 항 인간 호흡기 세포융합 바이러스 (ｈｒｓｖ) 나노바디 구조물
WO2011064382A1 (en)	2009-11-30	2011-06-03	Ablynx N.V.	Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
WO2011083141A2 (en)	2010-01-08	2011-07-14	Ablynx Nv	Method for generation of immunoglobulin sequences by using lipoprotein particles
NL2013661B1 (en)	2014-10-21	2016-10-05	Ablynx Nv	KV1.3 Binding immunoglobulins.
IL317416A (en)	2016-11-16	2025-02-01	Ablynx Nv	T cell-recruiting polypeptides capable of binding CD123 and TCR alpha/beta
TW202000238A (zh)	2018-02-26	2020-01-01	比利時商艾伯林克斯公司	編碼肽連接子之經改良核苷酸序列

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ240921A (en) *	1990-12-12	1994-06-27	Zymogenetics Inc	G protein coupled glutamate receptor (neurotransmitters), recombinant production
US5385831A (en) *	1990-12-12	1995-01-31	Zymogenetics, Inc.	Method for producing a mammalian G protein coupled glutamate receptor
JPH07502641A (ja) *	1991-04-02	1995-03-23	ベイラーカレッジオブメディシン	高親和性グルタミン酸塩／アスパラギン酸塩取り込みシステム
GB9112504D0 (en) *	1991-06-11	1991-07-31	Merck Sharp & Dohme	Cell line
WO1993007161A1 (en) *	1991-10-04	1993-04-15	Cornell Research Foundation, Inc.	Molecular cloning and transformation of cyclodiene resistance
US5527703A (en) *	1994-05-25	1996-06-18	Merck & Co., Inc.	DNA encoding glutamate gated chloride channels

1995
- 1995-05-05 US US08/435,933 patent/US5693492A/en not_active Expired - Lifetime
1996
- 1996-05-01 DE DE69635455T patent/DE69635455T2/de not_active Expired - Lifetime
- 1996-05-01 WO PCT/US1996/006035 patent/WO1996034940A1/en not_active Ceased
- 1996-05-01 JP JP53343596A patent/JP3862278B2/ja not_active Expired - Lifetime
- 1996-05-01 EP EP96913285A patent/EP0871703B1/de not_active Expired - Lifetime
- 1996-05-01 ES ES96913285T patent/ES2250989T3/es not_active Expired - Lifetime
- 1996-05-01 CA CA2220116A patent/CA2220116C/en not_active Expired - Lifetime
- 1996-05-01 AT AT96913285T patent/ATE310098T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0871703A1 (de)	1998-10-21
US5693492A (en)	1997-12-02
ES2250989T3 (es)	2006-04-16
EP0871703A4 (de)	2000-03-01
JPH11506906A (ja)	1999-06-22
WO1996034940A1 (en)	1996-11-07
DE69635455T2 (de)	2006-08-03
CA2220116A1 (en)	1996-11-07
CA2220116C (en)	2011-04-19
JP3862278B2 (ja)	2006-12-27
EP0871703B1 (de)	2005-11-16
DE69635455D1 (de)	2005-12-22

Legal Events

Date	Code	Title	Description
2006-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69635455D1 (de)	2005-12-22	Dna kodierend für glutaminsäure-gesteuerte chloridkanäle
DE69633825D1 (de)	2004-12-16	Modifiziertes enzym mit lipolytischer aktivität
DE69638032D1 (de)	2009-11-05	Modifiziertes bacillus thuringiensis gen zur kontrolle von lepidoptera in pflanzen
BR9508981A (pt)	1997-12-30	Mutantes de subtilisina isentos de cálcio
ATE389666T1 (de)	2008-04-15	Hohe expressionsrate von proteinen
DE69635452D1 (de)	2005-12-22	Hohe expressionsrate des grün-fluoreszierenden proteins
ATE449175T1 (de)	2009-12-15	Bakterielle produktion von interferon-beta polypeptiden
ATE283368T1 (de)	2004-12-15	Für die glutamatabhängigen chloridkanäle kodierende dna
EP0967283A4 (de)	2004-06-09	Gene, die für proteine mit transglykolysierungsaktivität kodieren.
DE69736389D1 (de)	2006-09-07	Proteine mit zellulase-aktivitäten und prozess für ihre herstellung
WO2000063415A8 (en)	2001-01-18	Dna encoding the human vanilloid receptor vr1
CA2032167A1 (en)	1990-11-02	Dna coding for protein binds to enhancer of.alpha.-fetoprotein gene
ATE372375T1 (de)	2007-09-15	Für den bradykinin-b1-rezeptor kodierende dna
ATE384739T1 (de)	2008-02-15	Für den menschlichen vanilloid-rezeptor vr3 kodierende dns
ATE345382T1 (de)	2006-12-15	2,6-beta-d-fruktanhydrolase enzym und verfahren zu dessen verwendung
DE60129688D1 (de)	2007-09-13	Die menschliche beta-1a-untereinheit des potential-abhängigen natriumkanals und deren verwendungen
DE60033297D1 (de)	2007-03-22	Für die humane untereinheit 5-ht3-c des serotoninrezeptors 5-ht3 kodierende dna
MY104405A (en)	1994-03-31	Structural gene comprising dna coding for an endotoxin protein having toxic activity against insects.
ATE266094T1 (de)	2004-05-15	Produktion des proteins ingap mit hoher expressionsrate
ATE309371T1 (de)	2005-11-15	Protein mit dnase-aktivität
DE69127743D1 (de)	1997-10-30	Für ein Protein, das sich mit dem Enhancer des Alpha-Fetoprotein verbindet, kodierende DNS
KR950704352A (ko)	1995-11-20	테라포시데 아포노펠마로부터의 칼슘 통로 차단 폴리펩티드(calcium channel blocking polypeptides from theraphosidae aphonopelma)
FI883775A7 (fi)	1988-08-15	Kloonatut streptokokkigeenit, jotka koodaavat proteiinia G, ja niiden käyttö proteiinia G tuottavien rekombinantti-mikro-organismien konstru oimiseksi.