NO970626L - Fremgangsmåte for å diagnostisere disponering for bryst- og ovariekreft - Google Patents

Fremgangsmåte for å diagnostisere disponering for bryst- og ovariekreft

Info

Publication number
NO970626L
NO970626L NO970626A NO970626A NO970626L NO 970626 L NO970626 L NO 970626L NO 970626 A NO970626 A NO 970626A NO 970626 A NO970626 A NO 970626A NO 970626 L NO970626 L NO 970626L
Authority
NO
Norway
Prior art keywords
ovarian cancer
gene
human
breast
mutations
Prior art date
Application number
NO970626A
Other languages
English (en)
Other versions
NO970626D0 (no
Inventor
Mark H Skolnick
David E Goldgar
Yoshio Miki
Jeff Swenson
Alexander Kamb
Keith D Harshman
Donna M Shattuck-Eidens
Sean V Tavtigian
Roger W Wiseman
Andrew P Futreal
Original Assignee
Myriad Genetics Inc
Us Health
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27575337&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO970626(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/483,554 external-priority patent/US5747282A/en
Priority claimed from US08/487,002 external-priority patent/US5710001A/en
Application filed by Myriad Genetics Inc, Us Health, Univ Utah Res Found filed Critical Myriad Genetics Inc
Publication of NO970626D0 publication Critical patent/NO970626D0/no
Publication of NO970626L publication Critical patent/NO970626L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Foreliggende oppfinnelse vedrører generelt området human genetikk. Spesielt vedrøres fremgangsmåter og materialer benyttet til å isolere og detektere et human bryst- og ovariekreft predisponeringsgen (BRCA1), noen mutantalleler av hvilket forårsaker mottagelighet for kreft, særlig bryst- og ovariekreft. Mer spesielt vedrøres kjønnscelle-mutasjoner i BRCA1 genet og-deres bruk i diagnose av predisponering av human bryst- og ovariekreft. Ytterligere vedrører oppfinnelsen somatiske mutasjoner i BRCA1 genet i human bryst- og ovariekreft og deres anvendelse i diagnose og prognose av human bryst- og ovariekreft. 1 tillegg vedrøres somatiske mutasjoner i BRCA1 genet i andre humane kreftformer og deres bruk i diagnose og prognose av humane krefttyper. Oppfinnelsen vedrører også behandling av human kreft som har mutasjoner i BRGA1 genet inkludert genterapi, proteinerstatningsterapi og proteinetteriigninger. Det beskrives videre screening av legemidler for kreftbehandling. Endelig beskrives screening av BRCA1 genet for mutasjoner, som er nyttig for diagnostisering av predisponering av bryst- og ovariekreft.
NO970626A 1994-08-12 1997-02-11 Fremgangsmåte for å diagnostisere disponering for bryst- og ovariekreft NO970626L (no)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US28922194A 1994-08-12 1994-08-12
US30026694A 1994-09-02 1994-09-02
US30810494A 1994-09-16 1994-09-16
US34882494A 1994-11-29 1994-11-29
US40930595A 1995-03-24 1995-03-24
US48801195A 1995-06-07 1995-06-07
US08/483,554 US5747282A (en) 1994-08-12 1995-06-07 17Q-linked breast and ovarian cancer susceptibility gene
US08/487,002 US5710001A (en) 1994-08-12 1995-06-07 17q-linked breast and ovarian cancer susceptibility gene
PCT/US1995/010220 WO1996005308A1 (en) 1994-08-12 1995-08-11 Method for diagnosing a predisposition for breast and ovarian cancer

Publications (2)

Publication Number Publication Date
NO970626D0 NO970626D0 (no) 1997-02-11
NO970626L true NO970626L (no) 1997-04-14

Family

ID=27575337

Family Applications (2)

Application Number Title Priority Date Filing Date
NO970626A NO970626L (no) 1994-08-12 1997-02-11 Fremgangsmåte for å diagnostisere disponering for bryst- og ovariekreft
NO970625A NO970625L (no) 1994-08-12 1997-02-11 17q-koblete bryst- og ovariekreft mottagelighetsgener

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO970625A NO970625L (no) 1994-08-12 1997-02-11 17q-koblete bryst- og ovariekreft mottagelighetsgener

Country Status (15)

Country Link
EP (2) EP0705902B2 (no)
JP (1) JP3399539B2 (no)
CN (1) CN1159829A (no)
AT (2) ATE198623T1 (no)
AU (2) AU691958B2 (no)
CA (2) CA2196795C (no)
DE (2) DE69519834T3 (no)
DK (2) DK0705902T3 (no)
ES (2) ES2154712T5 (no)
FI (2) FI970515A7 (no)
GR (1) GR3035631T3 (no)
NO (2) NO970626L (no)
NZ (1) NZ291624A (no)
PT (2) PT699754E (no)
WO (2) WO1996005307A2 (no)

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EP0699754B1 (en) 2001-01-10
EP0705902B2 (en) 2008-08-06
WO1996005308A1 (en) 1996-02-22
DE69519834T2 (de) 2001-04-26
ES2154712T3 (es) 2001-04-16
DE69524182T3 (de) 2009-07-09
DE69519834T3 (de) 2010-04-01
FI970514A0 (fi) 1997-02-07
AU691331B2 (en) 1998-05-14
CA2196790A1 (en) 1996-02-22
PT699754E (pt) 2001-04-30
ES2154712T5 (es) 2009-12-14
DE69524182T2 (de) 2002-05-29
WO1996005307A2 (en) 1996-02-22
AU691958B2 (en) 1998-05-28
NO970626D0 (no) 1997-02-11
ES2164136T5 (es) 2009-02-16
NO970625L (no) 1997-04-14
DK0705902T3 (da) 2002-03-11
FI970515A0 (fi) 1997-02-07
DE69524182D1 (de) 2002-01-10
CA2196790C (en) 2000-10-10
EP0699754A1 (en) 1996-03-06
FI970514A7 (fi) 1997-04-07
DK0699754T3 (da) 2001-02-26
AU3321695A (en) 1996-03-07
NO970625D0 (no) 1997-02-11
CA2196795A1 (en) 1996-02-22
JP3399539B2 (ja) 2003-04-21
FI970515A7 (fi) 1997-04-07
EP0705902A1 (en) 1996-04-10
EP0699754B2 (en) 2009-08-12
ATE209660T1 (de) 2001-12-15
AU3242895A (en) 1996-03-07
NZ291624A (en) 1998-07-28
CA2196795C (en) 2001-04-03
ATE198623T1 (de) 2001-01-15
GR3035631T3 (en) 2001-06-29
WO1996005307A3 (en) 1996-03-14
PT705902E (pt) 2002-05-31
ES2164136T3 (es) 2002-02-16
DE69519834D1 (de) 2001-02-15
JP2002502227A (ja) 2002-01-22
CN1159829A (zh) 1997-09-17
EP0705902B1 (en) 2001-11-28

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