NO971218D0 - Tetrahydrofuran-antifungale midler - Google Patents

Tetrahydrofuran-antifungale midler

Info

Publication number
NO971218D0
NO971218D0 NO971218A NO971218A NO971218D0 NO 971218 D0 NO971218 D0 NO 971218D0 NO 971218 A NO971218 A NO 971218A NO 971218 A NO971218 A NO 971218A NO 971218 D0 NO971218 D0 NO 971218D0
Authority
NO
Norway
Prior art keywords
antifungal agents
tetrahydrofuran
tetrahydrofuran antifungal
agents
antifungal
Prior art date
Application number
NO971218A
Other languages
English (en)
Norwegian (no)
Other versions
NO971218L (no
Inventor
Anil K Saksena
Viyyoor M Girijavallabhan
Raymond G Lovey
Russel E Pike
Haiyan Wang
Yi-Tsung Liu
Ashit Kumar Ganguly
Frank Bennett
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/459,145 external-priority patent/US5693626A/en
Priority claimed from US08/459,225 external-priority patent/US5710154A/en
Priority claimed from US08/458,543 external-priority patent/US5714490A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO971218L publication Critical patent/NO971218L/no
Publication of NO971218D0 publication Critical patent/NO971218D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO971218A 1995-06-02 1997-03-17 Tetrahydrofuran-antifungale midler NO971218D0 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/459,145 US5693626A (en) 1993-12-21 1995-06-02 Tetrahydrofuran antifungals
US08/459,225 US5710154A (en) 1993-12-21 1995-06-02 Tetrahydrofuran antifungals
US08/458,543 US5714490A (en) 1993-12-21 1995-06-02 Tetrahydrofuran antifungals
PCT/US1996/007547 WO1996038443A1 (en) 1995-06-02 1996-05-30 Tetrahydrofuran antifungals

Publications (2)

Publication Number Publication Date
NO971218L NO971218L (no) 1997-03-17
NO971218D0 true NO971218D0 (no) 1997-03-17

Family

ID=27412736

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971218A NO971218D0 (no) 1995-06-02 1997-03-17 Tetrahydrofuran-antifungale midler

Country Status (18)

Country Link
EP (1) EP0773941B1 (de)
CN (1) CN1073109C (de)
AR (1) AR002751A1 (de)
AT (1) ATE240319T1 (de)
AU (1) AU5928096A (de)
CA (1) CA2197672C (de)
CZ (1) CZ59497A3 (de)
DE (1) DE69628117T2 (de)
ES (1) ES2199291T3 (de)
HU (1) HUP9701690A3 (de)
IL (1) IL118464A (de)
MX (1) MX9701229A (de)
NO (1) NO971218D0 (de)
NZ (1) NZ309281A (de)
PL (1) PL319635A1 (de)
SK (1) SK27097A3 (de)
TW (1) TW357146B (de)
WO (1) WO1996038443A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1238353C (zh) * 1997-02-11 2006-01-25 詹森药业有限公司 含氨基酸酯之唑类抗真菌剂
JP2001519346A (ja) * 1997-10-07 2001-10-23 シェーリング コーポレイション 抗真菌性結晶性多形物
WO1999018111A1 (en) * 1997-10-07 1999-04-15 Schering Corporation Crystalline antifungal glycine ester polymorph
US6713481B1 (en) * 1997-10-17 2004-03-30 David R. Andrews Crystalline antifungal polymorph
US5883097A (en) * 1998-04-16 1999-03-16 Schering Corporation Soluble azole antifungal salt
EP0957101A1 (de) * 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Wasserlösliche Azole als Breitspektrum-antifungus
WO2000030655A1 (en) 1998-11-20 2000-06-02 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
BR0010279A (pt) * 1999-05-04 2002-05-14 Janssen Phamaceutica N V éteres antifúngicos
US6362172B2 (en) 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds
EP2130540A1 (de) 2008-06-02 2009-12-09 Sandoz AG Pharmazeutische Zusammensetzungen mit einer kristallinen Form von Posaconazol
EP2141159A1 (de) 2008-07-03 2010-01-06 Sandoz AG Kristalline Form von Posaconazol
CA2767489A1 (en) 2009-07-09 2011-01-13 Sandoz Ag A crystalline form of posaconazole
CN102234267A (zh) * 2010-04-21 2011-11-09 中国科学院上海药物研究所 新型三氮唑类抗真菌化合物、其药物组合物及其制备方法和用途
CN102892763B (zh) * 2010-05-19 2016-03-09 桑多斯股份公司 泊沙康唑及泊沙康唑中间体的纯化
EP2571847B1 (de) 2010-05-19 2016-09-21 Sandoz AG Verfahren zur herstellung chiraler hydrazide
AU2011254654B2 (en) 2010-05-19 2016-01-07 Sandoz Ag Process for the preparation of chiral triazolones
US9073904B2 (en) 2010-05-19 2015-07-07 Sandoz Ag Preparation of posaconazole intermediates
CN103635465A (zh) 2011-06-16 2014-03-12 桑多斯股份公司 制备手性化合物的方法
WO2015011224A1 (en) 2013-07-25 2015-01-29 Sandoz Ag Improved process for the preparation of crystalline form iv of posaconazole
ITMI20132114A1 (it) 2013-12-18 2015-06-19 Djada Pharmaceutical Sa Una forma cristallina di posaconazolo
CN104370894A (zh) * 2014-10-21 2015-02-25 江苏恒盛药业有限公司 无定型泊沙康唑的制备工艺
CN105622591B (zh) * 2014-11-06 2018-09-21 博瑞生物医药（苏州）股份有限公司 一种新型三唑类抗真菌药物的制备方法
WO2016087880A1 (en) 2014-12-05 2016-06-09 Pulmocide Limited Antimycotic compound
ES2790723T3 (es) 2015-05-21 2020-10-29 Pulmocide Ltd Antifúngico 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-il)metil)-5-(2,4-difluorofenil)tetrahidrofurano-3-il)metoxi)-3-metilfenil)piperazina-1-il)-N -(2-hidroxiciclohexil)benzamida, o una sal farmacéuticamente aceptable del mismo
CN106432338A (zh) * 2015-08-08 2017-02-22 陕西合成药业股份有限公司 泊沙康唑衍生物、合成和在长效制剂中的用途
CN105606736A (zh) * 2016-01-27 2016-05-25 重庆华邦制药有限公司 分离测定泊沙康唑中间体z1及其有关物质的方法
US10517867B2 (en) 2016-02-04 2019-12-31 Wuhan Ll Science And Technology Development Co., Ltd. Posaconazole derivative, pharmaceutical composition and use thereof
CN105949278B (zh) * 2016-03-30 2019-12-06 南京曼杰生物科技有限公司 一种取代的四氢呋喃水溶性衍生物及其应用
CN106866459A (zh) * 2017-03-30 2017-06-20 成都绿林科技有限公司 一种抗真菌药物中间体的制备方法
CN106986787A (zh) * 2017-03-30 2017-07-28 成都绿林科技有限公司 一种泊沙康唑中间体的合成方法
CN110938093B (zh) * 2018-09-21 2022-08-19 华创合成制药股份有限公司 一种泊沙康唑磷酸酯单胆碱盐及其制备方法和用途
GB201917867D0 (en) 2019-12-06 2020-01-22 Pulmocide Ltd Polymorphs
CN113666915B (zh) * 2021-08-27 2022-08-16 江苏海洋大学 一种泊沙康唑中间体的制备方法
CN114315811B (zh) * 2021-11-19 2024-04-30 江苏恒盛药业有限公司 一种三氮唑类似物化合物及其制备方法和应用
CN118164968A (zh) * 2024-01-26 2024-06-11 四川大学 一种三唑类抗真菌药伏立康唑的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL103558A0 (en) * 1991-10-30 1993-03-15 Schering Corp Tri-substituted tetrahydrofuran antifungals
DK0736030T3 (da) * 1993-12-21 2001-10-29 Schering Corp Fungicide tetrahydrofuraner
SG48386A1 (en) * 1994-01-24 1998-04-17 Janssen Pharmaceutica Nv Watersoluble azole antifungals

Also Published As

Publication number Publication date
CA2197672A1 (en) 1996-12-05
AU5928096A (en) 1996-12-18
CN1073109C (zh) 2001-10-17
CZ59497A3 (en) 1997-08-13
DE69628117D1 (de) 2003-06-18
NO971218L (no) 1997-03-17
ES2199291T3 (es) 2004-02-16
HUP9701690A2 (hu) 1998-03-02
IL118464A0 (en) 1996-09-12
ATE240319T1 (de) 2003-05-15
MX9701229A (es) 1997-05-31
SK27097A3 (en) 1997-09-10
NZ309281A (en) 1998-07-28
HK1008821A1 (en) 1999-05-21
PL319635A1 (en) 1997-08-18
EP0773941A1 (de) 1997-05-21
TW357146B (en) 1999-05-01
HUP9701690A3 (en) 1998-04-28
AR002751A1 (es) 1998-04-29
CN1161038A (zh) 1997-10-01
EP0773941B1 (de) 2003-05-14
DE69628117T2 (de) 2004-04-01
IL118464A (en) 2000-08-13
WO1996038443A1 (en) 1996-12-05
CA2197672C (en) 2011-05-17

Similar Documents

Publication Publication Date Title
DE69628117D1 (de) Antifungale tetrahydrofurane
NO304430B1 (no) Antifungale midler
DE69621528D1 (de) Anti-inflamatorische agenzien
NO981133D0 (no) Ikke-reseptormedierte kontrastmidler
DE69635700D1 (de) Neue endoglukanase
FI965115A7 (fi) Uudet pestisidit
PT828506E (pt) Agentes endoparasiticidas
FI962577L (fi) Antifungaaliset tetrahydrofuraanit
FI951637A0 (fi) Pakkausmateriaali
BR9608862A (pt) Telefone
EP0833628A4 (de) Neue taxoide
DE69519127D1 (de) Inzektizide Tetrahydrofuranverbindung
BR9609298A (pt) Agentes antifungos de triazola
FI973812L (fi) Antifungaalisia koostumuksia
FI954953A0 (fi) Lämm¦siirtoneste
FI953062A0 (fi) Infrapunasäteilijä
DK0777044T3 (da) Fristempel-Vuillermier-maskine
FI961894A7 (fi) Käsipuhelinlaite
FI950785A0 (fi) Menetelmä massan valkaisemiseksi
GB9621971D0 (en) Antifungal agents
BR9604659A (pt) Máquina arrotadora-carpidora
KR970047909U (ko) 전화기용 조이스틱
DE59603934D1 (de) Niotensidkonzentrate
KR970039385U (ko) 다리미
FI973261A0 (fi) Puhelinasema

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application