NO972943L - 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende dem og deres anvendelse - Google Patents

4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende dem og deres anvendelse

Info

Publication number: NO972943L
Authority: NO; Norway
Prior art keywords: amino; ureido; pyrimidine; processes; preparation
Prior art date: 1996-06-24

Application number

NO972943A

Other languages

English (en)

Other versions

NO972943D0 (no

NO312414B1 (no

Inventor

Hans Georg Boeger

Axel Hoffmann

Gerhard Jaehne

Norbert Krass

Hans-Ludwig Schaefer

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-24

Filing date

1997-06-23

Publication date

1997-12-29

1997-06-23 Application filed by Hoechst Ag filed Critical Hoechst Ag

1997-06-23 Publication of NO972943D0 publication Critical patent/NO972943D0/no

1997-12-29 Publication of NO972943L publication Critical patent/NO972943L/no

2002-05-06 Publication of NO312414B1 publication Critical patent/NO312414B1/no

Links

SHGZREYDEWHPDB-UHFFFAOYSA-N 4-amino-2-(carbamoylamino)pyrimidine-5-carboxamide Chemical class NC(=O)NC1=NC=C(C(N)=O)C(N)=N1 SHGZREYDEWHPDB-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
NKTWBSSRNCDNCD-UHFFFAOYSA-N 4-amino-2-(2-oxoimidazolidin-1-yl)pyrimidine-5-carboxamide Chemical class N1=C(N)C(C(=O)N)=CN=C1N1C(=O)NCC1 NKTWBSSRNCDNCD-UHFFFAOYSA-N 0.000 abstract 1
125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO19972943A 1996-06-24 1997-06-23 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende demog deres anvendelse NO312414B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19625089A DE19625089A1 (de)	1996-06-24	1996-06-24	4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

Publications (3)

Publication Number	Publication Date
NO972943D0 NO972943D0 (no)	1997-06-23
NO972943L true NO972943L (no)	1997-12-29
NO312414B1 NO312414B1 (no)	2002-05-06

Family

ID=7797762

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19972943A NO312414B1 (no)	1996-06-24	1997-06-23	4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende demog deres anvendelse

Country Status (11)

Country	Link
US (1)	US5939424A (no)
EP (1)	EP0816358B1 (no)
JP (1)	JP4101906B2 (no)
AT (1)	ATE281452T1 (no)
CA (1)	CA2208630C (no)
DE (2)	DE19625089A1 (no)
DK (1)	DK0816358T3 (no)
ES (1)	ES2230575T3 (no)
MX (1)	MX9704704A (no)
NO (1)	NO312414B1 (no)
PT (1)	PT816358E (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19625088A1 (de) *	1996-06-24	1998-01-02	Hoechst Ag	4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US6887712B1 (en) *	1998-11-09	2005-05-03	Atherogenics, Inc.	Methods and compositions to lower plasma cholesterol levels
WO2001027105A1 (en) *	1999-10-12	2001-04-19	Takeda Chemical Industries, Ltd.	Pyrimidine-5-carboxamide compounds, process for producing the same and use thereof
US7176310B1 (en)	2002-04-09	2007-02-13	Ucb Sa	Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents
CA2553968A1 (en) *	2004-01-23	2005-08-11	Amgen Inc.	Vanilloid receptor ligands and their use in treatments of inflammatory and neuropathic pain
JP2011057661A (ja) *	2009-08-14	2011-03-24	Bayer Cropscience Ag	殺虫性カルボキサミド類

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2853220A1 (de) *	1978-12-09	1980-07-03	Hoechst Ag	Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
DE3522940A1 (de) *	1985-06-27	1987-01-08	Hoechst Ag	4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln
EP0577877B1 (en) *	1991-09-04	1995-10-18	Sumitomo Electric Industries, Ltd.	Adjusting shim
DE59307402D1 (de) *	1992-02-22	1997-10-30	Hoechst Ag	Lösliche Salze von 4-Amino-2-(4,4-dimethyl-imidazolidin-2-on-1-yl)-pyrimidin-5 -carbonsäure- N-methyl-N-(3-trifluormethyl-phenyl)- amid, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Ausgangsprodukte
ATE147384T1 (de) *	1992-02-22	1997-01-15	Hoechst Ag	4-amino-2-ureido-pyrimidin-5-carbonsäureamide, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
DE19625088A1 (de) *	1996-06-24	1998-01-02	Hoechst Ag	4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

1996
- 1996-06-24 DE DE19625089A patent/DE19625089A1/de not_active Withdrawn
1997
- 1997-06-04 US US08/868,991 patent/US5939424A/en not_active Expired - Lifetime
- 1997-06-12 DE DE59712053T patent/DE59712053D1/de not_active Expired - Lifetime
- 1997-06-12 DK DK97109547T patent/DK0816358T3/da active
- 1997-06-12 ES ES97109547T patent/ES2230575T3/es not_active Expired - Lifetime
- 1997-06-12 EP EP97109547A patent/EP0816358B1/de not_active Expired - Lifetime
- 1997-06-12 AT AT97109547T patent/ATE281452T1/de active
- 1997-06-12 PT PT97109547T patent/PT816358E/pt unknown
- 1997-06-23 JP JP16581597A patent/JP4101906B2/ja not_active Expired - Fee Related
- 1997-06-23 NO NO19972943A patent/NO312414B1/no not_active IP Right Cessation
- 1997-06-23 MX MX9704704A patent/MX9704704A/es active IP Right Grant
- 1997-06-23 CA CA002208630A patent/CA2208630C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP4101906B2 (ja)	2008-06-18
DE19625089A1 (de)	1998-01-02
EP0816358A1 (de)	1998-01-07
ATE281452T1 (de)	2004-11-15
PT816358E (pt)	2005-01-31
DE59712053D1 (de)	2004-12-09
JPH1072463A (ja)	1998-03-17
NO972943D0 (no)	1997-06-23
MX9704704A (es)	1997-12-31
EP0816358B1 (de)	2004-11-03
DK0816358T3 (da)	2005-03-07
US5939424A (en)	1999-08-17
ES2230575T3 (es)	2005-05-01
CA2208630A1 (en)	1997-12-24
CA2208630C (en)	2006-07-11
NO312414B1 (no)	2002-05-06

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Legal Events

Date	Code	Title	Description
2015-01-26	MM1K	Lapsed by not paying the annual fees