ATE96144T1 - 2-aminoacetamid derivate. - Google Patents

2-aminoacetamid derivate.

Info

Publication number: ATE96144T1
Authority: AT; Austria
Prior art keywords: compounds; pharmaceutically acceptable; sedatives; epilepsy; diluent
Prior art date: 1988-01-20

Application number

AT89300164T

Other languages

English (en)

Inventor

Ronald Conrad Griffith

Original Assignee

Fisons Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-20

Filing date

1989-01-10

Publication date

1993-11-15

1988-01-20 Priority claimed from US07/145,866 external-priority patent/US4871872A/en

1989-01-10 Application filed by Fisons Corp filed Critical Fisons Corp

1993-11-15 Application granted granted Critical

1993-11-15 Publication of ATE96144T1 publication Critical patent/ATE96144T1/de

Links

BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical class NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000002671 adjuvant Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
206010015037 epilepsy Diseases 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940125723 sedative agent Drugs 0.000 abstract 1
239000000932 sedative agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT89300164T 1988-01-20 1989-01-10 2-aminoacetamid derivate. ATE96144T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US14594388A	1988-01-20	1988-01-20
US14586588A	1988-01-20	1988-01-20
US07/145,866 US4871872A (en)	1988-01-20	1988-01-20	2-[(2-aminoacetyl)amino]acetamide derivatives
EP89300164A EP0326240B1 (de)	1988-01-20	1989-01-10	2-Aminoacetamid Derivate

Publications (1)

Publication Number	Publication Date
ATE96144T1 true ATE96144T1 (de)	1993-11-15

Family

ID=27386328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89300164T ATE96144T1 (de)	1988-01-20	1989-01-10	2-aminoacetamid derivate.

Country Status (9)

Country	Link
EP (2)	EP0401253A1 (de)
JP (1)	JPH02503089A (de)
AT (1)	ATE96144T1 (de)
CA (1)	CA1315477C (de)
DE (1)	DE68909961T2 (de)
DK (1)	DK460789A (de)
IE (1)	IE890161L (de)
PT (1)	PT89483B (de)
WO (1)	WO1989006646A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2083972T3 (es) *	1988-08-12	1996-05-01	Astra Ab	Arilalquil-aminas y -amidas con propiedades anticonvulsivas y neuroprotectoras.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2449638A (en) *	1946-05-10	1948-09-21	Wyeth Corp	Substituted glycinamides
DE955508C (de) *	1954-07-28	1957-01-03	Cilag Ag	Verfahren zur Herstellung von antikonvulsivisch wirkenden Carbonsaeureamiden
GB1420067A (en) *	1972-02-15	1976-01-07	Astra Laekemedel Ab	Aryldiamides
SE408171B (sv) *	1975-09-04	1979-05-21	Astra Laekemedel Ab	Analogiforfarande for framstellning av nya aralkylamider av 2-aminopropropionsyra, vilka amider har framakologiska egenskaper

1989
- 1989-01-10 JP JP1502245A patent/JPH02503089A/ja active Pending
- 1989-01-10 WO PCT/US1989/000041 patent/WO1989006646A1/en not_active Ceased
- 1989-01-10 EP EP89902415A patent/EP0401253A1/de active Pending
- 1989-01-10 AT AT89300164T patent/ATE96144T1/de not_active IP Right Cessation
- 1989-01-10 EP EP89300164A patent/EP0326240B1/de not_active Expired - Lifetime
- 1989-01-10 DE DE89300164T patent/DE68909961T2/de not_active Expired - Fee Related
- 1989-01-19 IE IE890161A patent/IE890161L/xx unknown
- 1989-01-19 PT PT89483A patent/PT89483B/pt active IP Right Grant
- 1989-01-20 CA CA000588803A patent/CA1315477C/en not_active Expired - Fee Related
- 1989-09-19 DK DK460789A patent/DK460789A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0326240A1 (de)	1989-08-02
JPH02503089A (ja)	1990-09-27
PT89483B (pt)	1994-02-28
EP0401253A1 (de)	1990-12-12
DK460789A (da)	1989-11-20
EP0326240B1 (de)	1993-10-20
DE68909961T2 (de)	1994-02-10
PT89483A (pt)	1989-10-04
CA1315477C (en)	1993-03-30
WO1989006646A1 (en)	1989-07-27
DE68909961D1 (de)	1993-11-25
IE890161L (en)	1989-07-20
DK460789D0 (da)	1989-09-19

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Legal Events

Date	Code	Title	Description
1994-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties