NO973367L - Fremgangsmåte for å inhibere miljömessige östrogen - Google Patents

Fremgangsmåte for å inhibere miljömessige östrogen

Info

Publication number
NO973367L
NO973367L NO973367A NO973367A NO973367L NO 973367 L NO973367 L NO 973367L NO 973367 A NO973367 A NO 973367A NO 973367 A NO973367 A NO 973367A NO 973367 L NO973367 L NO 973367L
Authority
NO
Norway
Prior art keywords
inhibiting
environmental estrogen
inhibiting environmental
estrogen
hexemethylenimino
Prior art date
Application number
NO973367A
Other languages
English (en)
Other versions
NO973367D0 (no
Inventor
Henry U Bryant
Jeffrey A Dodge
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO973367L publication Critical patent/NO973367L/no
Publication of NO973367D0 publication Critical patent/NO973367D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Det er beskrevet en fremgangsmåte for å inhibere effektene av miljømessige østrogener innbefattende administrering til et menneske eller annet dyr som har behov for dette av en effektiv mengde av en forbindelse som har formel I, hvor R' og R' uavhengig av hverandre er hydrogen, -CHj, (a) eller (b), hvor Ar er eventuelt substituert fenyl; R^ er valgt fra gruppen bestående av pyrrolidin, hexemetylenimino og piperidino, eller et farmasøytisk akseptabelt salt eller solvat derav.
NO973367A 1995-01-25 1997-07-21 Fremgangsmåte for å inhibere miljömessige östrogen NO973367D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/378,229 US5521214A (en) 1995-01-25 1995-01-25 Methods of inhibiting environmental estrogens
PCT/US1996/000902 WO1996022771A1 (en) 1995-01-25 1996-01-22 Methods of inhibiting environmental estrogens

Publications (2)

Publication Number Publication Date
NO973367L true NO973367L (no) 1997-07-21
NO973367D0 NO973367D0 (no) 1997-07-21

Family

ID=23492278

Family Applications (1)

Application Number Title Priority Date Filing Date
NO973367A NO973367D0 (no) 1995-01-25 1997-07-21 Fremgangsmåte for å inhibere miljömessige östrogen

Country Status (13)

Country Link
US (1) US5521214A (no)
EP (1) EP0806950A4 (no)
JP (1) JPH10512886A (no)
KR (1) KR19980701589A (no)
CN (1) CN1169116A (no)
AU (1) AU699678B2 (no)
CA (1) CA2210940A1 (no)
CZ (1) CZ233797A3 (no)
EA (1) EA199700136A1 (no)
FI (1) FI973095A7 (no)
HU (1) HUP9800550A3 (no)
NO (1) NO973367D0 (no)
WO (1) WO1996022771A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2219377A1 (en) 1996-10-30 1998-04-30 Eli Lilly And Company Improvements in or relating to the prophylaxis of breast cancer
GB9624800D0 (en) * 1996-11-29 1997-01-15 Lilly Co Eli Methods of preventing breast cancer
US5760030A (en) * 1997-06-30 1998-06-02 Eli Lilly And Company Benzothiophene compounds and methods of use
CN1250563C (zh) 1999-05-04 2006-04-12 斯特拉坎有限公司 雄激素糖苷及其产生雄性征的活性
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
KR100334130B1 (ko) * 2000-02-18 2002-04-26 정명식 에스트로겐 유사물질의 생물학적 분석방법
KR100368936B1 (ko) * 2000-10-04 2003-01-24 주식회사 대웅 우루소데옥시콜린산을 함유한 환경호르몬 독성의 예방 및치료제
CN1273144C (zh) * 2000-11-28 2006-09-06 三菱制药株式会社 蓄积性含氯化合物的排泄促进剂
US7720727B2 (en) * 2001-03-01 2010-05-18 Fisher-Rosemount Systems, Inc. Economic calculations in process control system
CN112424205B (zh) * 2018-07-12 2023-10-31 伊莱利利公司 选择性的雌激素受体降解剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
US5593987A (en) * 1993-12-21 1997-01-14 Eli Lilly And Company Methods of inhibiting breast disorders
US5451590A (en) * 1993-12-21 1995-09-19 Eli Lilly & Co. Methods of inhibiting sexual precocity

Also Published As

Publication number Publication date
CN1169116A (zh) 1997-12-31
KR19980701589A (ko) 1998-05-15
EA199700136A1 (ru) 1997-12-30
HUP9800550A2 (hu) 1998-12-28
US5521214A (en) 1996-05-28
CZ233797A3 (cs) 1998-02-18
NO973367D0 (no) 1997-07-21
EP0806950A1 (en) 1997-11-19
FI973095A0 (fi) 1997-07-23
EP0806950A4 (en) 1999-01-07
WO1996022771A1 (en) 1996-08-01
AU699678B2 (en) 1998-12-10
FI973095L (fi) 1997-07-24
HUP9800550A3 (en) 1999-10-28
AU4764996A (en) 1996-08-14
JPH10512886A (ja) 1998-12-08
CA2210940A1 (en) 1996-08-01
FI973095A7 (fi) 1997-07-24
MX9705537A (es) 1997-10-31

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