NO973980L - Imidazolderivater og medisinsk preparat - Google Patents

Imidazolderivater og medisinsk preparat

Info

Publication number
NO973980L
NO973980L NO973980A NO973980A NO973980L NO 973980 L NO973980 L NO 973980L NO 973980 A NO973980 A NO 973980A NO 973980 A NO973980 A NO 973980A NO 973980 L NO973980 L NO 973980L
Authority
NO
Norway
Prior art keywords
imidazole derivatives
medical preparations
lower alkyl
represents hydrogen
mastopathy
Prior art date
Application number
NO973980A
Other languages
English (en)
Other versions
NO973980D0 (no
Inventor
Toru Yoden
Minoru Okada
Isao Kinoyama
Tsukasa Ishihara
Syuichi Sakuda
Yukitaka Ideyama
Masafumi Kudoh
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO973980D0 publication Critical patent/NO973980D0/no
Publication of NO973980L publication Critical patent/NO973980L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Imidazolderivater og medisinsk preparat Imidazolderivater representert ved generell formel (I) ;n^^n3 (I) salter derav, hydrater derav eller solvater derav, hvori A betegner lavere alkylen som kan være substi- tuert med hydroxy, aryl, lavere alkyliden eller oxo (=0), X beteg- 2 1 ner methylen eller -NR -, R betegner hydrogen, lavere alkyl eller aral- 2 kyl, og R betegner hydrogen eller lavere alkyl. Forbindelsene har en steroid 17-20-lyaseinhibiberende aktivitet og er anvendbare for behandling og forhindring av prostatisk kreft, prostatisk hyper- trofi, brystkreft, mastopati, uterus myoma og endometriose.
NO973980A 1995-03-01 1997-08-29 Imidazolderivater og medisinsk preparat NO973980L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4206795 1995-03-01
PCT/JP1996/000490 WO1996026927A1 (en) 1995-03-01 1996-03-01 Imidazole derivatives and medicinal composition thereof

Publications (2)

Publication Number Publication Date
NO973980D0 NO973980D0 (no) 1997-08-29
NO973980L true NO973980L (no) 1997-10-31

Family

ID=12625750

Family Applications (1)

Application Number Title Priority Date Filing Date
NO973980A NO973980L (no) 1995-03-01 1997-08-29 Imidazolderivater og medisinsk preparat

Country Status (10)

Country Link
EP (1) EP0820989A4 (no)
KR (1) KR19980702319A (no)
CN (1) CN1177350A (no)
AU (1) AU702406B2 (no)
CA (1) CA2213246A1 (no)
HU (1) HUP9801158A3 (no)
NO (1) NO973980L (no)
NZ (1) NZ302392A (no)
PL (1) PL322028A1 (no)
WO (1) WO1996026927A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1073640B1 (en) 1998-04-23 2005-04-13 Takeda Pharmaceutical Company Limited Naphthalene derivatives, their production and use
JP4546589B2 (ja) * 1998-04-23 2010-09-15 武田薬品工業株式会社 ナフタレン誘導体
PE20010781A1 (es) 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
AU7950100A (en) * 1999-10-22 2001-05-08 Takeda Chemical Industries Ltd. 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof
JP4520012B2 (ja) * 1999-10-22 2010-08-04 武田薬品工業株式会社 １−置換−１−（１ｈ−イミダゾール−４−イル）メタノール類
CA2431171A1 (en) * 2000-12-08 2002-06-13 Takeda Chemical Industries, Ltd. Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof
US7880017B2 (en) 2003-11-11 2011-02-01 Allergan, Inc. Process for the synthesis of imidazoles
US7183305B2 (en) 2003-11-11 2007-02-27 Allergan, Inc. Process for the synthesis of imidazoles
US8080566B1 (en) 2008-06-11 2011-12-20 Kalypsys, Inc Carbazole inhibitors of histamine receptors for the treatment of disease
JP6275378B2 (ja) * 2012-12-26 2018-02-07 エヌ・イーケムキャット株式会社 カルバゾール類の製造方法およびこの方法により製造されたカルバゾール類。
US20170158636A1 (en) * 2014-07-16 2017-06-08 Novogen Ltd. Functionalised and substituted carbazoles as anti-cancer agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5753466A (en) * 1980-09-17 1982-03-30 Dai Ichi Seiyaku Co Ltd 2-substituted imidazole compound
US4533670A (en) * 1983-09-21 1985-08-06 Eli Lilly And Company Anti-convulsant fluorenylalkylimidazole derivatives, compositions, and method of use
NZ221729A (en) * 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
GB9310635D0 (en) * 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
AU7275894A (en) * 1993-08-04 1995-02-28 Yamanouchi Pharmaceutical Co., Ltd. Imidazolylalkylamine derivative and pharmaceutical composition thereof

Also Published As

Publication number Publication date
CN1177350A (zh) 1998-03-25
NZ302392A (en) 1998-08-26
PL322028A1 (en) 1998-01-05
HUP9801158A2 (hu) 1999-08-30
AU4843996A (en) 1996-09-18
MX9706585A (es) 1997-11-29
NO973980D0 (no) 1997-08-29
KR19980702319A (ko) 1998-07-15
EP0820989A1 (en) 1998-01-28
EP0820989A4 (en) 1998-05-06
WO1996026927A1 (en) 1996-09-06
HUP9801158A3 (en) 1999-11-29
CA2213246A1 (en) 1996-09-06
AU702406B2 (en) 1999-02-18

Similar Documents

Publication Publication Date Title
NO961274L (no) Azolderivat og farmasöytiske preparat derav
JP4949982B2 (ja) エストロンスルファターゼインヒビターとしての非ステロイド多環式環スルファメート誘導体、それらの調製および使用
NO973980L (no) Imidazolderivater og medisinsk preparat
DE60040142D1 (de) Pyridin-imin polymerisationskatalysator
UA84407C2 (en) Acetyl 2-hydroxy-1,3 diaminoalkanes
ATE195530T1 (de) 17-ether und thioether von 4-aza-steroiden
KR910004651A (ko) 5α-환원효소 억제제로서의 17β-아실-4-아자-5α-안드로스트-1-엔-3-온
NO20065784L (no) Steroidforbindelser og anvendelse av slike
RU94036772A (ru) Применение 2-фенил-3-ароилбензотиофенов для ингибирования эндометриоза
CA2377803A1 (en) Phenyl sulfamate derivatives
RU94037235A (ru) Ингибитор фиброза матки
NO964095L (no) Nye hydroksypyridinoner
RU2009114753A (ru) Терапевтически активные триазолы и их использование
KR950032267A (ko) 11,21-비스페닐-19-노르프레그난 유도체
DK1077218T3 (da) Peptidomimetiske forbindelser omfattende RGD-sekvenser, som er nyttige som integrininhibitorer
RU94037246A (ru) Применение 2-фенил-3-ароилбензотиофенов для ингибирования разрушения хряща
ZA888008B (en) Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
DE60216239D1 (de) Verwendung von cyclohexenon derivaten zur herstellung eines medikaments für die behandlung von dysurie
AU7950100A (en) 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof
NO994903L (no) Behandling eller profylakse av prostatakreft og benign prostatahyperplasi med selektive östrogenreseptormodulatorer
Banting 4 Inhibition of aromatase
ID24566A (id) Obat untuk alopesia
AU2002214320A1 (en) Imidazole derivatives, process for their preparation and their use
TR200003877T2 (tr) İnsan CD23 üretiminin ve TNF salınmasının ihhibitörleri olan hiydroxamic acid türevleri
DE69305684D1 (de) Octahydronaphthalenoxim Derivate für die Inhibierung der Cholesterin Biosynthese, ihre Herstellung und Verwendung