NO975584L - Blokkpolyerer som har funksjonelle grupper ved begge ender - Google Patents
Blokkpolyerer som har funksjonelle grupper ved begge enderInfo
- Publication number
- NO975584L NO975584L NO975584A NO975584A NO975584L NO 975584 L NO975584 L NO 975584L NO 975584 A NO975584 A NO 975584A NO 975584 A NO975584 A NO 975584A NO 975584 L NO975584 L NO 975584L
- Authority
- NO
- Norway
- Prior art keywords
- group
- functional groups
- block polymer
- terminal
- block polymers
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 125000000524 functional group Chemical group 0.000 title abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 125000003172 aldehyde group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000000560 biocompatible material Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 239000000693 micelle Substances 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/668—Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/676—Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds in which at least one of the two components contains aliphatic unsaturation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
- C08G63/912—Polymers modified by chemical after-treatment derived from hydroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
- C08G65/2618—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen
- C08G65/2621—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups
- C08G65/2627—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups containing aromatic or arylaliphatic amine groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G85/00—General processes for preparing compounds provided for in this subclass
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Polyesters Or Polycarbonates (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Graft Or Block Polymers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Polyethers (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20454795 | 1995-08-10 | ||
| PCT/JP1996/002200 WO1997006202A1 (en) | 1995-08-10 | 1996-08-05 | Block polymer having functional groups at both ends |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO975584L true NO975584L (no) | 1997-12-03 |
| NO975584D0 NO975584D0 (no) | 1997-12-03 |
| NO314589B1 NO314589B1 (no) | 2003-04-14 |
Family
ID=16492323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19975584A NO314589B1 (no) | 1995-08-10 | 1997-12-03 | Blokkpolymer som har funksjonelle grupper ved begge ender, levende blokkpolymer, fremgangsmåte for fremstilling av blokkpolymeren samtpolymermicelle |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5929177A (no) |
| EP (1) | EP0844269B1 (no) |
| JP (1) | JP3711288B2 (no) |
| KR (1) | KR19990014879A (no) |
| CN (1) | CN1087317C (no) |
| AT (1) | ATE226604T1 (no) |
| AU (1) | AU726749B2 (no) |
| BR (1) | BR9610053A (no) |
| CA (1) | CA2229068A1 (no) |
| DE (1) | DE69624488T2 (no) |
| HU (1) | HUP9900662A3 (no) |
| IL (1) | IL122021A0 (no) |
| NO (1) | NO314589B1 (no) |
| NZ (1) | NZ313769A (no) |
| RU (1) | RU2174989C2 (no) |
| SI (1) | SI9620107A (no) |
| WO (1) | WO1997006202A1 (no) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9524475D0 (en) * | 1995-11-30 | 1996-01-31 | Zeneca Ltd | Compound preparation and use |
| JP4581248B2 (ja) * | 1998-05-07 | 2010-11-17 | 日油株式会社 | 片末端に保護されていてもよいアミノ基を有するポリオキシエチレン誘導体及びその製造方法 |
| DE19930729A1 (de) * | 1999-07-05 | 2001-01-11 | Achim Goepferich | Blockcopolymere zur Herstellung biomimetischer Oberflächen |
| JP2001048978A (ja) | 1999-08-04 | 2001-02-20 | Nano Career Kk | オキサゾリン由来のポリマーセグメントを有するブロックコポリマー |
| JP2001131271A (ja) * | 1999-11-04 | 2001-05-15 | Kazunori Kataoka | ポリマーミセルの層の積層した表面およびその作成方法 |
| CA2389917A1 (en) | 1999-11-04 | 2001-05-10 | Kazunori Kataoka | A polymer micelle as monolayer or layer-laminated surface |
| JP4659937B2 (ja) * | 1999-11-19 | 2011-03-30 | ナノキャリア株式会社 | コア−シェル構造のポリイオンコンプレックスミセル |
| JP2001208754A (ja) * | 2000-01-26 | 2001-08-03 | Kazunori Kataoka | 生物学的な被検体を検出するための組成物 |
| AU5667901A (en) * | 2000-05-11 | 2001-11-20 | Center For Advanced Science And Technology Incubation, Ltd. | Polymer composition for forming surface of biosensor |
| US7217770B2 (en) * | 2000-05-17 | 2007-05-15 | Samyang Corporation | Stable polymeric micelle-type drug composition and method for the preparation thereof |
| US20050059031A1 (en) * | 2000-10-06 | 2005-03-17 | Quantum Dot Corporation | Method for enhancing transport of semiconductor nanocrystals across biological membranes |
| EP2085781B2 (en) * | 2000-10-06 | 2020-03-11 | Life Technologies Corporation | Transfectable micelles containing semiconductor nanocrystals |
| DE10101387A1 (de) | 2001-01-13 | 2002-07-18 | Merck Patent Gmbh | Polyester mit Methacrylatendgruppen |
| US6939564B2 (en) * | 2001-06-08 | 2005-09-06 | Labopharm, Inc. | Water-soluble stabilized self-assembled polyelectrolytes |
| US7094810B2 (en) * | 2001-06-08 | 2006-08-22 | Labopharm, Inc. | pH-sensitive block copolymers for pharmaceutical compositions |
| KR100566911B1 (ko) | 2001-06-25 | 2006-04-03 | 주식회사 삼양사 | 약물 전달체용 음이온기-함유 양친성 블록 공중합체 및 그의 양이온성 약물과의 복합체 |
| CA2450949C (en) * | 2001-06-28 | 2009-04-28 | John Samuel | Methods and compositions for polyene antibiotics with reduced toxicity |
| US7009033B2 (en) * | 2001-07-02 | 2006-03-07 | Polymer Source Inc. | Heterofunctional polyethylene glycol and polyethylene oxide, process for their manufacture |
| JP4063510B2 (ja) * | 2001-07-13 | 2008-03-19 | ナノキャリア株式会社 | 薬物含有高分子ミセルの凍結乾燥用組成物およびその凍結乾燥製剤 |
| KR100527291B1 (ko) * | 2001-07-14 | 2005-11-09 | 주식회사 삼양사 | 약물 전달체용 양이온기-함유 양친성 블록 공중합체 및그의 음이온성 약물과의 복합체 |
| ATE406436T1 (de) | 2001-07-26 | 2008-09-15 | Transparent Inc | Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon |
| US6592899B2 (en) | 2001-10-03 | 2003-07-15 | Macromed Incorporated | PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water |
| CA2463517C (en) * | 2001-10-18 | 2010-03-16 | Samyang Corporation | Ph responsive biodegradable polylactic acid derivatives forming polymeric micelles and uses thereof for poorly water soluble drug delivery |
| KR100492805B1 (ko) * | 2001-10-18 | 2005-06-07 | 주식회사 삼양사 | 안정성이 향상된 고분자 미셀 조성물 |
| KR100531269B1 (ko) * | 2001-12-04 | 2005-11-28 | 주식회사 삼양사 | 수용액에서 안정한 미셀 또는 나노 파티클을 형성하는고분자 조성물 |
| EP1489415A4 (en) * | 2002-03-11 | 2006-02-22 | Toudai Tlo Ltd | BRUSH-LIKE STRUCTURED SURFACE OF POLYETHYLENE OXIDE WITH INCREASED DENSITY |
| US20040005351A1 (en) * | 2002-03-29 | 2004-01-08 | Kwon Glen S. | Polymeric micelle formulations of hydrophobic compounds and methods |
| KR100502840B1 (ko) * | 2002-09-04 | 2005-07-21 | 학교법인 포항공과대학교 | 약물 담지능력이 우수한 블록 공중합체 미셀 조성물 |
| US20040116360A1 (en) * | 2002-10-15 | 2004-06-17 | Kwon Glen S. | Encapsulation and deaggregation of polyene antibiotics using poly(ethylene glycol)-phospholipid micelles |
| WO2004035013A2 (en) * | 2002-10-21 | 2004-04-29 | L'oreal | Process for dissolving lipophilic compounds, and cosmetic composition |
| KR20050054129A (ko) * | 2003-12-04 | 2005-06-10 | 주식회사 삼양사 | 고분자 미셀을 형성하는 생분해성 분지형 폴리락트산유도체, 및 그의 제조방법 및 용도 |
| CA2549524A1 (en) * | 2004-01-02 | 2005-07-28 | Wisconsin Alumni Research Foundation | Encapsulation of chemical compounds in fluorous-core and fluorous-inner-shell micelles formed from semifluorinated-block or fluorinated-block copolymers |
| WO2005073370A1 (ja) * | 2004-01-31 | 2005-08-11 | Transparent Inc. | 酵素複合体 |
| EP1796690A4 (en) * | 2004-09-22 | 2011-08-03 | Cartilix Inc | KNORPELFÜLLVORRICHTUNG |
| EP2067801A1 (en) * | 2005-01-04 | 2009-06-10 | Intezyne Technologies Incorporated | Synthesis of Hybrid Block Copolymers |
| US20110124840A1 (en) * | 2005-02-11 | 2011-05-26 | Kurt Breitenkamp | Synthesis of Homopolymers and Block Copolymers |
| DK2656840T3 (en) | 2005-06-09 | 2015-11-02 | Nanocarrier Co Ltd | Process for preparing polymerized platinum complex coordination compounds |
| DE102005033101A1 (de) * | 2005-07-15 | 2007-01-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Resorbierbare Polyetherester und ihre Verwendung zur Herstellung von medizinischen Implantaten |
| CN1304451C (zh) * | 2005-09-13 | 2007-03-14 | 华东师范大学 | 端醛基聚氧乙烯－二乙三胺五乙酸嵌段聚合物及其合成方法 |
| WO2007099660A1 (ja) | 2006-03-01 | 2007-09-07 | The University Of Tokyo | 核酸内包高分子ミセル複合体 |
| JPWO2007102608A1 (ja) * | 2006-03-06 | 2009-07-23 | ナノキャリア株式会社 | 疎水性化合物の安定化剤 |
| CA2650422A1 (en) * | 2006-04-24 | 2007-11-08 | Nanocarrier Co., Ltd. | Process for producing polymer micelles encapsulating low molecular weight drugs |
| CN101489574A (zh) | 2006-07-18 | 2009-07-22 | 那野伽利阿株式会社 | 内包生理活性多肽或蛋白质的高分子聚合物胶束及其制造方法 |
| MX2009003092A (es) * | 2006-09-22 | 2009-05-08 | Labopharm Inc | Composiciones y metodos para suministro de farmaco dirigido a ph. |
| JP5277599B2 (ja) * | 2006-09-29 | 2013-08-28 | 日油株式会社 | 生分解性ポリオキシアルキレン誘導体の製造方法 |
| WO2008062909A1 (en) | 2006-11-22 | 2008-05-29 | The University Of Tokyo | ENVIRONMENT-RESPONDING siRNA CARRIER USING DISULFIDE-BRIDGED POLYMERIC MICELLE |
| WO2008070490A2 (en) * | 2006-11-28 | 2008-06-12 | Wisconsin Alumni Research Foundation | Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics |
| WO2008071009A1 (en) * | 2006-12-15 | 2008-06-19 | The Governors Of The University Of Alberta | Novel ligand guided block copolymers for targeted drug delivery |
| US8900562B2 (en) * | 2007-01-12 | 2014-12-02 | Wisconsin Alumni Research Foundation | Semi-fluorinated block copolymers for delivery of therapeutic agents |
| US20100178316A1 (en) * | 2007-05-30 | 2010-07-15 | Anuj Chauhan | Extended release of bioactive molecules from silicone hydrogels |
| US8075909B2 (en) * | 2007-09-04 | 2011-12-13 | University Of Florida Research Foundation, Incorporated | Contact lens based bioactive agent delivery system |
| US20110060123A1 (en) | 2008-04-30 | 2011-03-10 | Kazunori Kataoka | Charge conversional ternary polyplex |
| JP5737705B2 (ja) * | 2008-05-02 | 2015-06-17 | 国立大学法人 筑波大学 | 高分子化環状ニトロキシドラジカル化合物およびその使用 |
| DK2305275T3 (da) | 2008-06-24 | 2013-10-07 | Nanocarrier Co Ltd | Væskesammensætning omfattende cisplatinkoordinerende forbindelse |
| CA2728960C (en) | 2008-06-26 | 2016-04-12 | Japan Science And Technology Agency | Polymer-metal complex composite having mri contrast ability and mri contrasting and/or antitumor composition using the same |
| JP5327800B2 (ja) * | 2009-07-31 | 2013-10-30 | 独立行政法人国立高等専門学校機構 | カルボキシル基を末端基とするポリオキシアルキレン誘導体の製造 |
| JP5522361B2 (ja) * | 2009-09-18 | 2014-06-18 | 国立大学法人 筑波大学 | ガンの中性子捕捉療法を可能とする架橋型ホウ素内包ミセル |
| US20110081293A1 (en) * | 2009-10-07 | 2011-04-07 | Sanford-Burnham Medical Research Institute | Methods and compositions related to clot-binding lipid compounds |
| JP4829351B2 (ja) | 2010-02-05 | 2011-12-07 | ナノキャリア株式会社 | 易崩壊型ポリマーミセル組成物 |
| WO2011127405A1 (en) | 2010-04-08 | 2011-10-13 | Sanford-Burnham Medical Research Institute | Methods and compositions for enhanced delivery of compounds |
| EP2572780B1 (en) | 2010-05-21 | 2018-07-11 | Japan Science And Technology Agency | Vesicles with encapsulated substance and production method therefor |
| EP2591792B1 (en) | 2010-07-09 | 2016-12-21 | The University of Tokyo | Composition for nucleic acid delivery, carrier composition, pharmaceutical composition using the composition for nucleic acid delivery or the carrier composition, and method for delivering nucleic acid |
| CN103328038A (zh) | 2010-12-01 | 2013-09-25 | 史拜诺莫度雷森公司 | 向神经解剖结构直接递送药剂 |
| WO2012118778A1 (en) | 2011-02-28 | 2012-09-07 | Sanford-Burnham Medical Research Institute | Truncated car peptides and methods and compositions using truncated car peptides |
| US10166295B2 (en) | 2011-06-02 | 2019-01-01 | Opko Biologics Ltd. | Pegylated OXM variants |
| US10179801B2 (en) | 2011-08-26 | 2019-01-15 | Sanford-Burnham Medical Research Institute | Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides |
| KR101286854B1 (ko) * | 2011-09-29 | 2013-07-17 | 중앙대학교 산학협력단 | 폴리락트산（ａ）과 폴리에틸렌글리콜（ｂ）로 이루어진 ｂａｂ형 삼중 블록 공중합체, 이의 제조방법 및 이를 이용한 약물전달체 |
| MX362432B (es) | 2012-06-04 | 2019-01-17 | Opko Biologics Ltd | Variantes de oxm pegilada. |
| CN103059289A (zh) * | 2013-01-08 | 2013-04-24 | 东南大学 | 一种聚乙二醇修饰的d-氨基葡萄糖及其合成和应用 |
| CN109663550B (zh) | 2013-03-01 | 2021-08-06 | 国立研究开发法人科学技术振兴机构 | 物质包封微囊及其制备方法 |
| CN105377302B (zh) | 2013-05-17 | 2018-05-11 | 那野伽利阿株式会社 | 聚合物胶束医药组合物 |
| JP2015046867A (ja) | 2013-07-31 | 2015-03-12 | 株式会社リコー | 撮像装置 |
| WO2015020026A1 (ja) | 2013-08-06 | 2015-02-12 | 独立行政法人科学技術振興機構 | 核酸内包高分子ミセル複合体及びその製造方法 |
| EP3037107B1 (en) | 2013-08-23 | 2019-10-09 | The University of Tokyo | Polymer nanoparticle composite and composition for mri imaging including same |
| JP5971264B2 (ja) | 2014-01-10 | 2016-08-17 | Ｊｆｅスチール株式会社 | 極厚肉油井管用ねじ継手 |
| US10500246B2 (en) | 2015-06-25 | 2019-12-10 | Sanford Burnham Prebys Medical Discovery Institute | Compositions for delivery to and treatment of atherosclerotic plaques |
| US20170044316A1 (en) | 2015-08-10 | 2017-02-16 | Gelest Technologies, Inc. | Bifunctional Poly(alkyleneoxides) with Aminoalkyl and Unsaturated Termini and Derivatives Thereof |
| JP7067959B2 (ja) * | 2017-03-08 | 2022-05-16 | 三洋化成工業株式会社 | 環状化合物組成物及びその製造方法 |
| WO2018204392A1 (en) | 2017-05-02 | 2018-11-08 | Stanford Burnham Prebys Medical Discovery Institute | Tumor associated monocyte/macrophage binding peptide and methods of use thereof |
| KR20190119433A (ko) * | 2018-04-12 | 2019-10-22 | 삼성전자주식회사 | 양자점 소자 및 전자 장치 |
| US12441776B2 (en) | 2018-11-30 | 2025-10-14 | Eirgen Pharma Ltd. | Oxyntomodulin peptide analog formulations |
| CN117159491A (zh) * | 2018-12-17 | 2023-12-05 | 吉爱希公司 | 包含亲水性第一嵌段、疏水性第二嵌段和能够与硫醇特异性结合的官能团的嵌段共聚物 |
| WO2020161602A1 (en) | 2019-02-04 | 2020-08-13 | University Of Tartu | Bi-specific extracellular matrix binding peptides and methods of use thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL75315A (en) * | 1984-05-25 | 1991-07-18 | Vestar Inc | Method for stabilization of vesicles |
| US5008109A (en) * | 1984-05-25 | 1991-04-16 | Vestar, Inc. | Vesicle stabilization |
| JPH02224822A (ja) * | 1989-02-27 | 1990-09-06 | Rikio Atobe | ベンダー用金型装置 |
| JPH02242822A (ja) * | 1989-03-16 | 1990-09-27 | Hodogaya Chem Co Ltd | ポリオキシアルキレン誘導体の製法 |
| JP2626654B2 (ja) * | 1990-03-31 | 1997-07-02 | 科学技術振興事業団 | 標的指向性高分子医薬化合物及びその中間体 |
| JPH0499731A (ja) * | 1990-08-15 | 1992-03-31 | Yoshiyuki Koyama | 高分子キヤリアーおよびそれを用いた複合体 |
| US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
| FR2678168B1 (fr) * | 1991-06-28 | 1993-09-03 | Rhone Poulenc Rorer Sa | Nanoparticules ayant un temps de capture par le dysteme reticulo endothelial allonge. |
| JPH05117385A (ja) * | 1991-10-31 | 1993-05-14 | Res Dev Corp Of Japan | ブロツク共重合体の製造法、ブロツク共重合体及び水溶性高分子抗癌剤 |
| KR940003548U (ko) * | 1992-08-14 | 1994-02-21 | 김형술 | 세탁물 건조기 |
| WO1994022053A1 (en) * | 1993-03-18 | 1994-09-29 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Chemical functionalization of polymers |
| KR0148704B1 (ko) * | 1994-01-10 | 1998-08-17 | 김상응 | 생체분해성 약물전달용 고분자 |
| JPH07247355A (ja) * | 1994-03-10 | 1995-09-26 | Nippon Oil & Fats Co Ltd | オリゴオキシアルキレン誘導体および生体適合性材料 |
| JP3481318B2 (ja) * | 1994-09-30 | 2003-12-22 | 剛 遠藤 | リビングポリマーの生長末端の変換とブロック共重合体の製造方法 |
| JP3485404B2 (ja) * | 1994-11-24 | 2004-01-13 | 竹本油脂株式会社 | ポリオレフィン系繊維用耐久親水処理剤及びこれを用いるポリオレフィン系繊維への耐久親水性付与方法 |
-
1996
- 1996-08-05 AU AU66310/96A patent/AU726749B2/en not_active Expired
- 1996-08-05 RU RU98104071/04A patent/RU2174989C2/ru not_active IP Right Cessation
- 1996-08-05 EP EP96925998A patent/EP0844269B1/en not_active Expired - Lifetime
- 1996-08-05 SI SI9620107A patent/SI9620107A/sl not_active IP Right Cessation
- 1996-08-05 CN CN96196186A patent/CN1087317C/zh not_active Expired - Lifetime
- 1996-08-05 US US09/011,329 patent/US5929177A/en not_active Expired - Lifetime
- 1996-08-05 KR KR1019970708224A patent/KR19990014879A/ko not_active Abandoned
- 1996-08-05 NZ NZ313769A patent/NZ313769A/en not_active IP Right Cessation
- 1996-08-05 AT AT96925998T patent/ATE226604T1/de not_active IP Right Cessation
- 1996-08-05 WO PCT/JP1996/002200 patent/WO1997006202A1/ja not_active Ceased
- 1996-08-05 CA CA002229068A patent/CA2229068A1/en not_active Abandoned
- 1996-08-05 JP JP50831597A patent/JP3711288B2/ja not_active Expired - Lifetime
- 1996-08-05 HU HU9900662A patent/HUP9900662A3/hu unknown
- 1996-08-05 DE DE69624488T patent/DE69624488T2/de not_active Expired - Lifetime
- 1996-08-05 BR BR9610053A patent/BR9610053A/pt not_active IP Right Cessation
-
1997
- 1997-08-05 IL IL12202197A patent/IL122021A0/xx unknown
- 1997-12-03 NO NO19975584A patent/NO314589B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE226604T1 (de) | 2002-11-15 |
| DE69624488D1 (de) | 2002-11-28 |
| AU6631096A (en) | 1997-03-05 |
| US5929177A (en) | 1999-07-27 |
| NZ313769A (en) | 2000-02-28 |
| EP0844269B1 (en) | 2002-10-23 |
| HUP9900662A3 (en) | 2006-04-28 |
| EP0844269A1 (en) | 1998-05-27 |
| CN1087317C (zh) | 2002-07-10 |
| RU2174989C2 (ru) | 2001-10-20 |
| AU726749B2 (en) | 2000-11-16 |
| IL122021A0 (en) | 1998-03-10 |
| HUP9900662A2 (hu) | 1999-06-28 |
| JP3711288B2 (ja) | 2005-11-02 |
| NO975584D0 (no) | 1997-12-03 |
| CA2229068A1 (en) | 1997-02-20 |
| WO1997006202A1 (en) | 1997-02-20 |
| DE69624488T2 (de) | 2003-06-26 |
| EP0844269A4 (en) | 1999-01-27 |
| SI9620107A (sl) | 1998-10-31 |
| KR19990014879A (ko) | 1999-02-25 |
| CN1192759A (zh) | 1998-09-09 |
| NO314589B1 (no) | 2003-04-14 |
| BR9610053A (pt) | 1999-07-06 |
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