NO975666L - Pyrrolderivater og medisinsk sammensetning - Google Patents

Pyrrolderivater og medisinsk sammensetning

Info

Publication number
NO975666L
NO975666L NO975666A NO975666A NO975666L NO 975666 L NO975666 L NO 975666L NO 975666 A NO975666 A NO 975666A NO 975666 A NO975666 A NO 975666A NO 975666 L NO975666 L NO 975666L
Authority
NO
Norway
Prior art keywords
substituted
aryl
pharmaceutical composition
medical composition
alkyl
Prior art date
Application number
NO975666A
Other languages
English (en)
Other versions
NO975666D0 (no
NO321606B1 (no
Inventor
Masami Tsuda
Mitsushi Tanaka
Ayatsugu Nakamura
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of NO975666D0 publication Critical patent/NO975666D0/no
Publication of NO975666L publication Critical patent/NO975666L/no
Publication of NO321606B1 publication Critical patent/NO321606B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/50Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19975666A 1995-06-07 1997-12-05 Pyrrolderivater og medisinsk sammensetning NO321606B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14069895 1995-06-07
PCT/JP1996/001526 WO1996040634A1 (en) 1995-06-07 1996-06-06 Pyrrole derivatives and medicinal composition

Publications (3)

Publication Number Publication Date
NO975666D0 NO975666D0 (no) 1997-12-05
NO975666L true NO975666L (no) 1998-02-09
NO321606B1 NO321606B1 (no) 2006-06-12

Family

ID=15274666

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975666A NO321606B1 (no) 1995-06-07 1997-12-05 Pyrrolderivater og medisinsk sammensetning

Country Status (20)

Country Link
US (2) US5998459A (no)
EP (1) EP0842923B1 (no)
JP (1) JP3160910B2 (no)
KR (1) KR100275222B1 (no)
CN (2) CN1090617C (no)
AT (1) ATE318799T1 (no)
AU (1) AU710683B2 (no)
BR (1) BR9608502A (no)
CA (1) CA2223918C (no)
DE (1) DE69635857T2 (no)
DK (1) DK0842923T3 (no)
ES (1) ES2259795T3 (no)
HU (1) HUP9802290A3 (no)
MX (1) MX9709475A (no)
NO (1) NO321606B1 (no)
NZ (1) NZ309151A (no)
PT (1) PT842923E (no)
RU (1) RU2166941C2 (no)
TW (1) TW504503B (no)
WO (1) WO1996040634A1 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2223918C (en) * 1995-06-07 2006-01-10 Nippon Shinyaku Co., Ltd. Pyrrole derivatives and medicinal composition
KR100485642B1 (ko) * 1996-03-18 2005-09-30 에자이 가부시키가이샤 축합고리함유카르복실산유도체
KR20010034114A (ko) * 1998-01-14 2001-04-25 니뽄 신야쿠 가부시키가이샤 칼륨 채널 활성화제
WO1999061016A1 (fr) * 1998-05-27 1999-12-02 Nippon Shinyaku Co., Ltd. Inhibiteurs de cyclo-oxygenase-2
KR20030019326A (ko) * 2000-03-21 2003-03-06 니뽄 신야쿠 가부시키가이샤 방출 제어형 경구 투여 제제
US20040067991A1 (en) * 2000-07-06 2004-04-08 Greig Nigel H Tetrahydrobenzothiazole analogues as neuroprotective agents
TWI239952B (en) 2001-03-14 2005-09-21 Nippon Shinyaku Co Ltd Stable crystals of pyrrole compound
US7759373B2 (en) * 2001-04-16 2010-07-20 Mitsubishi Tanabe Pharma Corporation Large conductance calcium-activated K channel opener
TWI271402B (en) * 2002-10-15 2007-01-21 Tanabe Seiyaku Co Large conductance calcium-activated K channel opener
EP1606284B1 (en) * 2003-03-13 2009-12-02 Vertex Pharmaceuticals Incorporated Compositions useful as protein kinase inhibitors
US20050075359A1 (en) * 2003-03-14 2005-04-07 Rikako Kono Large conductance calcium-activated K channel opener
GB0321509D0 (en) * 2003-09-13 2003-10-15 Astrazeneca Ab Chemical compounds
WO2005037271A2 (en) * 2003-10-17 2005-04-28 Tanabe Seiyaku Co., Ltd. Large conductance calcium-activated k channel opener
US7118801B2 (en) * 2003-11-10 2006-10-10 Gore Enterprise Holdings, Inc. Aerogel/PTFE composite insulating material
ITTO20040125A1 (it) * 2004-03-01 2004-06-01 Rotta Research Lab Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica
JP2005325103A (ja) * 2004-04-13 2005-11-24 Tanabe Seiyaku Co Ltd 医薬組成物
JP5388574B2 (ja) * 2005-05-31 2014-01-15 バーテックス ファーマシューティカルズ インコーポレイテッド イオンチャネルのモジュレーターとして有用なヘテロ環式類
PE20070341A1 (es) * 2005-07-29 2007-04-13 Wyeth Corp Derivados de pirrol como moduladores del receptor de progesterona
PE20070404A1 (es) * 2005-07-29 2007-05-10 Wyeth Corp Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona
US8575338B2 (en) * 2008-04-09 2013-11-05 Mitsubishi Tanabe Pharma Corporation Pyrimidine, pyridine and triazine derivatives as maxi-K channel openers
JP6596090B2 (ja) 2014-12-17 2019-10-23 キングス カレッジ ロンドン レチノイン酸受容体ベータ(RARβ)アゴニストとしてのビシクロヘテロアリール−ヘテロアリール−安息香酸化合物
GB201610867D0 (en) 2016-06-22 2016-08-03 King S College London Crystalline forms of a therapeutic compound and processes for their preparation

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD143426A1 (de) * 1979-05-07 1980-08-20 Karl Gewald Verfahren zur herstellung von 5,6-kondensierten 4-amino-3-cyan-pyridonen-(2)
US4431823A (en) * 1981-07-23 1984-02-14 Hoffmann-La Roche Inc. 1H-Pyrrole-3-carbonitrile-4(2-benzoyl)phenyl derivatives as intermediates for pyrrolo[3,4-D][2]benzazepines
FR2569189B1 (fr) * 1984-08-14 1986-12-19 Roussel Uclaf Nouveaux derives du pyrrole, leur procede de preparation et leur application comme pesticides
SE8500273D0 (sv) * 1985-01-22 1985-01-22 Leo Ab Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder
JPH0637389B2 (ja) * 1986-12-26 1994-05-18 北陸製薬株式会社 頻尿治療剤
IL87222A (en) * 1987-07-29 1993-04-04 American Cyanamid Co Arylpyrroles, methods for thepreparation thereof andinsecticidal, acaricidal andnematicidal compositionscontaining them
US4929634A (en) * 1987-10-23 1990-05-29 American Cyanamid Company Method of and bait compositions for controlling mollusks
US4886625A (en) * 1987-10-29 1989-12-12 Miles Inc. Functionalized conducting polymers and their use in diagnostic devices
DE3820190A1 (de) * 1988-06-14 1989-12-21 Cassella Ag Pyrrolderivate, ihre herstellung und ihre verwendung als pharmazeutische wirkstoffe
EP0358047A3 (en) * 1988-09-08 1991-05-29 American Cyanamid Company Method of controlling phytopathogenic fungi
US5021586A (en) * 1989-03-31 1991-06-04 Miles, Inc. Dithiophenylpyrrole derivative monomers for preparing semi-conducting polymers
IT1233715B (it) * 1989-07-14 1992-04-14 Menarini Farma Ind Uso in terapia della 10-ammino-5,6diidro-11h= dibenzo (b,e) azepina-6,11-dione e derivati, quali farmaci utili per il trattamento dell'incontinenza urinaria
US5210092A (en) * 1990-09-25 1993-05-11 Fujisawa Pharmaceutical Co., Ltd. Angiotensin ii antagonizing heterocyclic derivatives
WO1993019067A1 (en) * 1991-09-12 1993-09-30 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine derivatives as angiotensin ii antagonists
FR2698364B1 (fr) * 1992-11-24 1995-01-27 Synthelabo Dérivés de pyrrole, leur préparation et leur application en thérapeutique.
FR2706899A1 (en) * 1993-06-22 1994-12-30 Synthelabo Pyrrole derivatives, their preparation and their therapeutic application
US5359090A (en) * 1993-12-29 1994-10-25 American Cyanamid Company Alkoxymethylation of pyrroles
CA2223918C (en) * 1995-06-07 2006-01-10 Nippon Shinyaku Co., Ltd. Pyrrole derivatives and medicinal composition

Also Published As

Publication number Publication date
EP0842923A1 (en) 1998-05-20
EP0842923A4 (en) 1999-12-29
AU5910996A (en) 1996-12-30
CA2223918A1 (en) 1996-12-19
HUP9802290A2 (hu) 1999-10-28
RU2166941C2 (ru) 2001-05-20
ATE318799T1 (de) 2006-03-15
NZ309151A (en) 2000-01-28
WO1996040634A1 (en) 1996-12-19
KR100275222B1 (ko) 2001-02-01
KR19990022329A (ko) 1999-03-25
DE69635857T2 (de) 2006-10-19
BR9608502A (pt) 1999-07-06
JP3160910B2 (ja) 2001-04-25
CN1090617C (zh) 2002-09-11
HUP9802290A3 (en) 2002-02-28
TW504503B (en) 2002-10-01
US5998459A (en) 1999-12-07
ES2259795T3 (es) 2006-10-16
CN1349796A (zh) 2002-05-22
NO975666D0 (no) 1997-12-05
DK0842923T3 (da) 2006-06-19
EP0842923B1 (en) 2006-03-01
CN1186485A (zh) 1998-07-01
MX9709475A (es) 1998-02-28
US6172102B1 (en) 2001-01-09
NO321606B1 (no) 2006-06-12
CA2223918C (en) 2006-01-10
DE69635857D1 (de) 2006-04-27
PT842923E (pt) 2006-07-31
AU710683B2 (en) 1999-09-30

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