NO981814L - Nye heterocykliske forbindelser, fremgangsmÕte ved deres fremstilling og farmas°ytiske sammensetninger som inneholder dem - Google Patents

Nye heterocykliske forbindelser, fremgangsmÕte ved deres fremstilling og farmas°ytiske sammensetninger som inneholder dem

Info

Publication number: NO981814L
Authority: NO; Norway
Prior art keywords: alkyl; cycloalkyl; aryl; optionally substituted; preparation
Prior art date: 1997-04-25

Application number

NO981814A

Other languages

English (en)

Other versions

NO981814D0 (no

NO317742B1 (no

Inventor

Gurald Guillaumet

Isabelle Charton

Ahmed Mamai

Pierre Renard

Bruno Pfeiffer

Philippe Delagrange

Buatrice Guardiola

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-25

Filing date

1998-04-22

Publication date

1998-10-26

1998-04-22 Application filed by Adir filed Critical Adir

1998-04-22 Publication of NO981814D0 publication Critical patent/NO981814D0/no

1998-10-26 Publication of NO981814L publication Critical patent/NO981814L/no

2004-12-13 Publication of NO317742B1 publication Critical patent/NO317742B1/no

Links

150000001875 compounds Chemical class 0.000 title 1
150000002391 heterocyclic compounds Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 10
125000003118 aryl group Chemical group 0.000 abstract 6
125000003710 aryl alkyl group Chemical group 0.000 abstract 5
125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 4
125000000753 cycloalkyl group Chemical group 0.000 abstract 4
125000003342 alkenyl group Chemical group 0.000 abstract 3
125000000304 alkynyl group Chemical group 0.000 abstract 3
FTEDICXUYBLEMB-UHFFFAOYSA-N 1,2-benzoxathiine Chemical class C1=CC=C2OSC=CC2=C1 FTEDICXUYBLEMB-UHFFFAOYSA-N 0.000 abstract 1
HPARLNRMYDSBNO-UHFFFAOYSA-N 1,4-benzodioxine Chemical compound C1=CC=C2OC=COC2=C1 HPARLNRMYDSBNO-UHFFFAOYSA-N 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
-1 diastereoisomers Chemical class 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000004385 trihaloalkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)

NO19981814A 1997-04-25 1998-04-22 Nye heterocykliske forbindelser, fremgangsmate ved deres fremstilling ogfarmasoytiske sammensetninger som inneholder dem, samt anvendelse av forbindelsene for fremstilling av et medikament NO317742B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9705110A FR2762598A1 (fr)	1997-04-25	1997-04-25	Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent

Publications (3)

Publication Number	Publication Date
NO981814D0 NO981814D0 (no)	1998-04-22
NO981814L true NO981814L (no)	1998-10-26
NO317742B1 NO317742B1 (no)	2004-12-13

Family

ID=9506306

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19981814A NO317742B1 (no)	1997-04-25	1998-04-22	Nye heterocykliske forbindelser, fremgangsmate ved deres fremstilling ogfarmasoytiske sammensetninger som inneholder dem, samt anvendelse av forbindelsene for fremstilling av et medikament

Country Status (18)

Country	Link
US (1)	US5919814A (no)
EP (1)	EP0873993B1 (no)
JP (1)	JP4125418B2 (no)
CN (1)	CN1145622C (no)
AT (1)	ATE213496T1 (no)
AU (1)	AU736716B2 (no)
BR (1)	BR9801448B1 (no)
CA (1)	CA2235421C (no)
DE (1)	DE69803894T2 (no)
DK (1)	DK0873993T3 (no)
ES (1)	ES2173556T3 (no)
FR (1)	FR2762598A1 (no)
HU (1)	HU223468B1 (no)
NO (1)	NO317742B1 (no)
NZ (1)	NZ330279A (no)
PL (1)	PL198572B1 (no)
PT (1)	PT873993E (no)
ZA (1)	ZA983490B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19548708A1 (de) *	1995-12-23	1997-06-26	Merck Patent Gmbh	Cyclische Sulfone
FR2799757B1 (fr) *	1999-10-15	2001-12-14	Adir	Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2805993B1 (fr) *	2000-03-08	2004-01-16	Adir	Utilisation de ligands melatoninergiques pour l'obtention de compositions pharmaceutiques destinees a la prevention ou au traitement du developpement de la tolerance aux composes nitres
US6750213B2 (en)	2000-10-19	2004-06-15	Merck & Co., Inc.	Estrogen receptor modulators
WO2002032373A2 (en) *	2000-10-19	2002-04-25	Merck & Co., Inc.	Estrogen receptor modulators
CN100546992C (zh) *	2001-10-04	2009-10-07	旭瑞达有限公司	羟基封端的低聚膦酸酯
SI1501819T1 (sl)	2002-04-24	2011-01-31	Merck Sharp & Dohme	Modulatorji estrogen receptorjev
FR2918372B1 (fr) *	2007-07-02	2009-08-28	Servier Lab	Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2918370B1 (fr) *	2007-07-02	2009-08-28	Servier Lab	Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3737195A1 (de) *	1987-11-03	1989-05-18	Bayer Ag	Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2691149B1 (fr) *	1992-05-18	1994-07-08	Adir	Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2716680B1 (fr) *	1994-02-25	1996-04-05	Adir	Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

1997
- 1997-04-25 FR FR9705110A patent/FR2762598A1/fr not_active Withdrawn
1998
- 1998-04-20 CA CA002235421A patent/CA2235421C/fr not_active Expired - Fee Related
- 1998-04-22 NO NO19981814A patent/NO317742B1/no unknown
- 1998-04-23 DE DE69803894T patent/DE69803894T2/de not_active Expired - Fee Related
- 1998-04-23 DK DK98400987T patent/DK0873993T3/da active
- 1998-04-23 AT AT98400987T patent/ATE213496T1/de not_active IP Right Cessation
- 1998-04-23 EP EP98400987A patent/EP0873993B1/fr not_active Expired - Lifetime
- 1998-04-23 ES ES98400987T patent/ES2173556T3/es not_active Expired - Lifetime
- 1998-04-23 PT PT98400987T patent/PT873993E/pt unknown
- 1998-04-24 US US09/066,235 patent/US5919814A/en not_active Expired - Fee Related
- 1998-04-24 PL PL325989A patent/PL198572B1/pl unknown
- 1998-04-24 JP JP11497998A patent/JP4125418B2/ja not_active Expired - Fee Related
- 1998-04-24 NZ NZ330279A patent/NZ330279A/en unknown
- 1998-04-24 HU HU9800964A patent/HU223468B1/hu not_active IP Right Cessation
- 1998-04-24 CN CNB981073328A patent/CN1145622C/zh not_active Expired - Fee Related
- 1998-04-24 BR BRPI9801448-0A patent/BR9801448B1/pt not_active IP Right Cessation
- 1998-04-24 AU AU63591/98A patent/AU736716B2/en not_active Ceased
- 1998-04-24 ZA ZA983490A patent/ZA983490B/xx unknown

Also Published As

Publication number	Publication date
HK1014956A1 (en)	1999-10-08
JP4125418B2 (ja)	2008-07-30
US5919814A (en)	1999-07-06
NO981814D0 (no)	1998-04-22
FR2762598A1 (fr)	1998-10-30
AU6359198A (en)	1998-10-29
HUP9800964A3 (en)	2000-06-28
AU736716B2 (en)	2001-08-02
CA2235421C (fr)	2003-09-16
BR9801448A (pt)	2000-02-08
HU9800964D0 (en)	1998-06-29
ZA983490B (en)	1998-10-29
ES2173556T3 (es)	2002-10-16
NO317742B1 (no)	2004-12-13
JPH10298178A (ja)	1998-11-10
NZ330279A (en)	1998-11-25
EP0873993B1 (fr)	2002-02-20
DE69803894T2 (de)	2002-11-07
PL198572B1 (pl)	2008-06-30
BR9801448B1 (pt)	2009-01-13
CA2235421A1 (fr)	1998-10-25
CN1145622C (zh)	2004-04-14
ATE213496T1 (de)	2002-03-15
DE69803894D1 (de)	2002-03-28
DK0873993T3 (da)	2002-06-10
PT873993E (pt)	2002-07-31
CN1197797A (zh)	1998-11-04
EP0873993A1 (fr)	1998-10-28
HUP9800964A2 (hu)	2000-05-28
HU223468B1 (hu)	2004-07-28
PL325989A1 (en)	1998-10-26

Publication	Publication Date	Title
DK1142891T3 (da)	2007-08-27	Salte og amider af (-)cis-5-fluor-2'-deoxy-thiacytidin der er egnede til behandling af hepatitis B
ES2150642T3 (es)	2000-12-01	Nuevos derivados piridinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DE69812073D1 (de)	2003-04-17	Indolecarbonsäurederivate und ihre verwendung als arzneimittel
DK0662471T3 (da)	1998-12-21	Naphthalenderivater med affinitet over for melatonin-receptorer, fremgangsmåde til deres fremstilling og farmaceutiske samm
NO981814D0 (no)	1998-04-22	Nye heterocykliske forbindelser, fremgangsmÕte ved deres fremstilling og farmas÷ytiske sammensetninger som inneholder dem
NO982921L (no)	1998-12-28	Nye kromenforbindelser, en fremgangsmÕte for deres fremstilling og farmas°ytiske sammensetninger som inneholder disse
ATE106868T1 (de)	1994-06-15	N-((2-oxopyrrolidin-1-yl)acetyl>piperazin- derivate und arzneimittel gegen senile dementia.
TW333532B (en)	1998-06-11	Benzopyrans
NO305751B1 (no)	1999-07-19	Substituerte benzensulfonylurinstoffer og -tiourinstoffer, deres anvendelse for fremstilling av medikament eller diagnostikum, sÕvel som legemidler inneholdende forbindelsene
DE69519047D1 (de)	2000-11-16	Benzodioxan Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
NO961456D0 (no)	1996-04-12	Nye tricykliske amider, fremgangsmåter ved deres fremstilling og farmasöytiske sammensetninger som inneholder dem
DK0388049T3 (da)	1995-06-06	Penciclovirderivater til behandling af hepatitis B infektioner
DK0606175T3 (da)	1996-02-19	2-cyan-3-hydroxypropenamider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler samt farmaceutiske præparater med indhold deraf
DK406587D0 (da)	1987-08-04	1,4-dihydropyridinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
SE8902186L (sv)	1990-12-17	Nya polypeptider och deras anvaendning
DK161250C (da)	1991-12-09	Analogifremgangsmaade til fremstilling af 4-aroyl-imidazol-2-oner eller pharmaceutisk acceptable salte deraf
NZ223180A (en)	1989-11-28	Guanidinoacetic and ethanamidinoacetic acid derivatives and sweetening compositions
DK283189D0 (da)	1989-06-09	Phenothiazinderivater, deres fremstilling og farmaceutiske praeparater deraf
ATE122352T1 (de)	1995-05-15	3-(3-ethyl-1,2,4-oxadiazol-5-yl)-1- azabicycloheptan, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zubereitungen.
NO976101L (no)	1998-07-01	Nye ellipticinforbindelser, en fremgangsmÕte ved deres fremstilling, samt farmas°ytiske blandinger som inneholder dem
IT1230754B (it)	1991-10-29	Camposti con attivita' analgesica centrale.
IT1217657B (it)	1990-03-30	Composti con attivita' analgesica centrale