NO983182L - Nye sykloalkylsubstituertere imidazoler - Google Patents

Nye sykloalkylsubstituertere imidazoler

Info

Publication number: NO983182L
Authority: NO; Norway
Prior art keywords: cycloalkyl substituted; substituted imidazoles; new; new cycloalkyl; imidazoles
Prior art date: 1996-01-11

Application number

NO983182A

Other languages

English (en)

Norwegian (no)

Inventor

Jerry L Adams

Ravi S Garigipati

Margaret E Sorenson

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-11

Filing date

1998-07-10

Publication date

1998-09-09

1998-07-10 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1998-09-09 Publication of NO983182L publication Critical patent/NO983182L/no

Links

150000002460 imidazoles Chemical class 0.000 title abstract 2
125000000753 cycloalkyl group Chemical group 0.000 title 1
238000002360 preparation method Methods 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Detergent Compositions (AREA)

NO983182A 1996-01-11 1998-07-10 Nye sykloalkylsubstituertere imidazoler NO983182L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1001096P	1996-01-11	1996-01-11
PCT/US1997/000619 WO1997025048A1 (en)	1996-01-11	1997-01-10	Novel cycloalkyl substituted imidazoles

Publications (1)

Publication Number	Publication Date
NO983182L true NO983182L (no)	1998-09-09

Family

ID=21743297

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO983182A NO983182L (no)	1996-01-11	1998-07-10	Nye sykloalkylsubstituertere imidazoler

Country Status (24)

Country	Link
US (1)	US6329526B1 (de)
EP (1)	EP0889726B1 (de)
JP (1)	JP2000503304A (de)
CN (1)	CN1213305A (de)
AP (1)	AP9700912A0 (de)
AR (1)	AR005434A1 (de)
AT (1)	ATE276248T1 (de)
AU (1)	AU715315B2 (de)
BR (1)	BR9708149A (de)
CZ (1)	CZ218198A3 (de)
DE (1)	DE69730704T2 (de)
ES (1)	ES2229335T3 (de)
HU (1)	HUP9901233A2 (de)
ID (1)	ID18759A (de)
IL (1)	IL125224A0 (de)
MA (1)	MA24055A1 (de)
MX (1)	MX9805628A (de)
NO (1)	NO983182L (de)
NZ (1)	NZ330889A (de)
PL (1)	PL327939A1 (de)
TR (1)	TR199801350T2 (de)
UY (1)	UY24434A1 (de)
WO (1)	WO1997025048A1 (de)
ZA (1)	ZA97173B (de)

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US6046208A (en) *	1996-01-11	2000-04-04	Smithkline Beecham Corporation	Substituted imidazole compounds
AP9700912A0 (en)	1996-01-11	1997-01-31	Smithkline Beecham Corp	Novel cycloalkyl substituted imidazoles
EP0889887A4 (de) *	1996-03-25	2003-06-11	Smithkline Beecham Corp	Behandlung von verletzungen des zentralen nervensystems
EP0889888A4 (de) *	1996-03-25	2003-01-08	Smithkline Beecham Corp	Behandlung von verletzungen des zentralen nervensystems
EP0956018A4 (de)	1996-08-21	2000-01-12	Smithkline Beecham Corp	Imidazolverbindungen, deren zusammensetzungen und verwendung
US5929076A (en) *	1997-01-10	1999-07-27	Smithkline Beecham Corporation	Cycloalkyl substituted imidazoles
US6514977B1 (en)	1997-05-22	2003-02-04	G.D. Searle & Company	Substituted pyrazoles as p38 kinase inhibitors
US6979686B1 (en)	2001-12-07	2005-12-27	Pharmacia Corporation	Substituted pyrazoles as p38 kinase inhibitors
JP2002502380A (ja)	1997-05-22	2002-01-22	ジー．ディー．サールアンドカンパニー	ｐ３８キナーゼ阻害剤としてのピラゾール誘導体
US20020156104A1 (en)	1997-06-13	2002-10-24	Jerry L. Adams	Novel pyrazole and pyrazoline substituted compounds
CA2294137A1 (en)	1997-06-19	1998-12-23	Smithkline Beecham Corporation	Novel aryloxy substituted pyrimidine imidazole compounds
TW517055B (en)	1997-07-02	2003-01-11	Smithkline Beecham Corp	Novel substituted imidazole compounds
US7301021B2 (en)	1997-07-02	2007-11-27	Smithkline Beecham Corporation	Substituted imidazole compounds
US6562832B1 (en)	1997-07-02	2003-05-13	Smithkline Beecham Corporation	Substituted imidazole compounds
US6489325B1 (en)	1998-07-01	2002-12-03	Smithkline Beecham Corporation	Substituted imidazole compounds
AU8381098A (en)	1997-07-02	1999-01-25	Smithkline Beecham Corporation	Novel cycloalkyl substituted imidazoles
US6362193B1 (en)	1997-10-08	2002-03-26	Smithkline Beecham Corporation	Cycloalkenyl substituted compounds
AU1924699A (en)	1997-12-19	1999-07-12	Smithkline Beecham Corporation	Compounds of heteroaryl substituted imidazole, their pharmaceutical compositionsand uses
US6096899A (en) *	1998-04-14	2000-08-01	The Regents Of The University Of Michigan	Cylic imidazole compounds having relatively low hydrogen content and relatively high nitrogen content and polymers formed therefrom
GB9809869D0 (en) *	1998-05-09	1998-07-08	Medical Res Council	Inhibition of protein kinases
KR20010025087A (ko)	1998-05-22	2001-03-26	스튜어트 알. 수터	신규한 2-알킬 치환된 이미다졸 화합물
US6858617B2 (en)	1998-05-26	2005-02-22	Smithkline Beecham Corporation	Substituted imidazole compounds
WO2000010563A1 (en)	1998-08-20	2000-03-02	Smithkline Beecham Corporation	Novel substituted triazole compounds
AU1909200A (en)	1998-11-04	2000-05-22	Smithkline Beecham Corporation	Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines
US6239279B1 (en)	1998-12-16	2001-05-29	Smithkline Beecham Corporation	Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
US6930101B1 (en)	1999-05-17	2005-08-16	The Regents Of The University Of California	Thiazolopyrimidines useful as TNFα inhibitors
EP1223924A4 (de) *	1999-09-17	2004-07-14	Smithkline Beecham Corp	Verwendung von csaids bei rhinovirus-infektionen
EP1233951B1 (de)	1999-11-23	2005-06-01	SmithKline Beecham Corporation	3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
US6759410B1 (en)	1999-11-23	2004-07-06	Smithline Beecham Corporation	3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
DE60023025T2 (de)	1999-11-23	2006-07-13	Smithkline Beecham Corp.	3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
WO2001041760A2 (en)	1999-12-08	2001-06-14	Pharmacia Corporation	Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect
US7235551B2 (en)	2000-03-02	2007-06-26	Smithkline Beecham Corporation	1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
US6673818B2 (en)	2001-04-20	2004-01-06	Pharmacia Corporation	Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
US7473695B2 (en) *	2001-10-22	2009-01-06	Mitsubishi Tanabe Pharma Corporation	4-imidazolin-2-one compounds
WO2004004725A2 (en)	2002-07-09	2004-01-15	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
US20050009931A1 (en) *	2003-03-20	2005-01-13	Britten Nancy Jean	Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
MXPA05009978A (es) *	2003-03-20	2005-11-04	Pharmacia Corp	Formulacion dispersable de un agente antiinflamatorio.
US20050004098A1 (en) *	2003-03-20	2005-01-06	Britten Nancy Jean	Dispersible formulation of an anti-inflammatory agent
US20040214753A1 (en) *	2003-03-20	2004-10-28	Britten Nancy Jean	Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US7105467B2 (en) *	2003-07-08	2006-09-12	Pharmacore, Inc.	Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives
US7105707B2 (en) *	2003-12-17	2006-09-12	Pharmacore, Inc.	Process for preparing alkynyl-substituted aromatic and heterocyclic compounds
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
WO2006062069A1 (ja) *	2004-12-06	2006-06-15	Santen Pharmaceutical Co., Ltd.	ｐ３８ＭＡＰキナーゼ阻害剤を有効成分とする掻痒治療剤
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
JP2007145819A (ja) *	2005-10-28	2007-06-14	Tanabe Seiyaku Co Ltd	医薬組成物
WO2007056016A2 (en) *	2005-11-02	2007-05-18	Kemia, Inc.	Bisamide cytokine inhibitors
EP1992344A1 (de)	2007-05-18	2008-11-19	Institut Curie	P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind
EP2111861A1 (de)	2008-04-21	2009-10-28	Ranbaxy Laboratories Limited	Zusammensetzungen von Phosphodiesterase-IV-Hemmern
WO2013100208A1 (ja)	2011-12-28	2013-07-04	京都府公立大学法人	角膜内皮細胞の培養正常化
JP6730701B2 (ja)	2013-11-14	2020-07-29	学校法人同志社	細胞増殖促進または細胞障害抑制による角膜内皮治療薬
US10342786B2 (en)	2017-10-05	2019-07-09	Fulcrum Therapeutics, Inc.	P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
NZ762856A (en)	2017-10-05	2020-07-31	Fulcrum Therapeutics Inc	P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
US20240165148A1 (en)	2021-03-15	2024-05-23	Saul Yedgar	Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

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AP9700912A0 (en)	1996-01-11	1997-01-31	Smithkline Beecham Corp	Novel cycloalkyl substituted imidazoles
CN1213306A (zh)	1996-01-11	1999-04-07	史密丝克莱恩比彻姆公司	新的取代咪唑化合物
EP0883402A4 (de)	1996-01-11	1999-08-11	Smithkline Beecham Corp	Neue cycloalkyl substituierte imidazole
ZA97175B (en)	1996-01-11	1997-11-04	Smithkline Beecham Corp	Novel substituted imidazole compounds.
EP0889887A4 (de)	1996-03-25	2003-06-11	Smithkline Beecham Corp	Behandlung von verletzungen des zentralen nervensystems
EP0889888A4 (de)	1996-03-25	2003-01-08	Smithkline Beecham Corp	Behandlung von verletzungen des zentralen nervensystems
JP2000514088A (ja)	1996-11-20	2000-10-24	メルクエンドカンパニーインコーポレーテッド	グルカゴンアンタゴニストとしてのトリアリール置換イミダゾール

1997
- 1997-01-02 AP AP9700912A patent/AP9700912A0/xx unknown
- 1997-01-08 UY UY24434A patent/UY24434A1/es unknown
- 1997-01-08 MA MA24456A patent/MA24055A1/fr unknown
- 1997-01-09 ZA ZA97173A patent/ZA97173B/xx unknown
- 1997-01-10 US US09/101,416 patent/US6329526B1/en not_active Expired - Fee Related
- 1997-01-10 TR TR1998/01350T patent/TR199801350T2/xx unknown
- 1997-01-10 ES ES97905576T patent/ES2229335T3/es not_active Expired - Lifetime
- 1997-01-10 AR ARP970100105A patent/AR005434A1/es unknown
- 1997-01-10 ID IDP970056A patent/ID18759A/id unknown
- 1997-01-10 WO PCT/US1997/000619 patent/WO1997025048A1/en not_active Ceased
- 1997-01-10 BR BR9708149A patent/BR9708149A/pt unknown
- 1997-01-10 DE DE69730704T patent/DE69730704T2/de not_active Expired - Fee Related
- 1997-01-10 EP EP97905576A patent/EP0889726B1/de not_active Expired - Lifetime
- 1997-01-10 NZ NZ330889A patent/NZ330889A/xx unknown
- 1997-01-10 PL PL97327939A patent/PL327939A1/xx unknown
- 1997-01-10 HU HU9901233A patent/HUP9901233A2/hu unknown
- 1997-01-10 IL IL12522497A patent/IL125224A0/xx unknown
- 1997-01-10 CN CN97192881A patent/CN1213305A/zh active Pending
- 1997-01-10 CZ CZ982181A patent/CZ218198A3/cs unknown
- 1997-01-10 AU AU22425/97A patent/AU715315B2/en not_active Ceased
- 1997-01-10 JP JP9525466A patent/JP2000503304A/ja not_active Ceased
- 1997-01-10 AT AT97905576T patent/ATE276248T1/de not_active IP Right Cessation
1998
- 1998-07-10 NO NO983182A patent/NO983182L/no not_active Application Discontinuation
- 1998-07-10 MX MX9805628A patent/MX9805628A/es unknown

Also Published As

Publication number	Publication date
DE69730704D1 (de)	2004-10-21
JP2000503304A (ja)	2000-03-21
BR9708149A (pt)	1999-07-27
DE69730704T2 (de)	2005-09-22
IL125224A0 (en)	1999-03-12
AR005434A1 (es)	1999-06-23
PL327939A1 (en)	1999-01-04
UY24434A1 (es)	1997-06-06
AU715315B2 (en)	2000-01-20
HUP9901233A2 (hu)	2000-04-28
ID18759A (id)	1998-05-07
EP0889726A1 (de)	1999-01-13
WO1997025048A1 (en)	1997-07-17
EP0889726B1 (de)	2004-09-15
CN1213305A (zh)	1999-04-07
MX9805628A (es)	1998-11-29
NZ330889A (en)	2000-03-27
US6329526B1 (en)	2001-12-11
ZA97173B (en)	1997-07-18
AP9700912A0 (en)	1997-01-31
ES2229335T3 (es)	2005-04-16
CZ218198A3 (cs)	1999-09-15
TR199801350T2 (xx)	1998-10-21
EP0889726A4 (de)	1999-07-21
ATE276248T1 (de)	2004-10-15
AU2242597A (en)	1997-08-01
MA24055A1 (fr)	1997-10-01

Legal Events

Date	Code	Title	Description
2001-09-10	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO983182L (no)	1998-09-09	Nye sykloalkylsubstituertere imidazoler
NO975716L (no)	1998-02-04	Imidazolforbindelser
DE69724246D1 (de)	2003-09-25	Neue substituierte imidazolverbindungen
MY116478A (en)	2004-02-28	Tri-substituted imidazoles having multiple therapeutic properties
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