NO983285L - Pyrido-1,2,4-tiadiazin- og pyrido-1,4-tiazinderivater, deres fremstilling og anvendelse - Google Patents

Pyrido-1,2,4-tiadiazin- og pyrido-1,4-tiazinderivater, deres fremstilling og anvendelse

Info

Publication number: NO983285L
Authority: NO; Norway
Prior art keywords: pyrido; thiadiazine; preparation; thiazine derivatives; compounds
Prior art date: 1996-01-17

Application number

NO983285A

Other languages

English (en)

Norwegian (no)

Other versions

NO983285D0 (no

Inventor

Bernard Pirotte

Philippe Lebrun

Pascal De Tullio

Fabian Somers

Jacques Elie Delarge

Holger Claus Hansen

Flemming Elmelund Nielsen

John Bondo Hansen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-17

Filing date

1998-07-16

Publication date

1998-09-16

1998-07-16 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1998-07-16 Publication of NO983285D0 publication Critical patent/NO983285D0/no

1998-09-16 Publication of NO983285L publication Critical patent/NO983285L/no

Links

IJVLTOQSGLWUMT-UHFFFAOYSA-N 2h-pyrido[2,3-e][1,2,4]thiadiazine Chemical compound C1=CN=C2NC=NSC2=C1 IJVLTOQSGLWUMT-UHFFFAOYSA-N 0.000 title abstract 2
PTITYRPDHMISBW-UHFFFAOYSA-N 2h-pyrido[3,2-b][1,4]thiazine Chemical class C1=CN=C2N=CCSC2=C1 PTITYRPDHMISBW-UHFFFAOYSA-N 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
210000000748 cardiovascular system Anatomy 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000005095 gastrointestinal system Anatomy 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000002685 pulmonary effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Obesity (AREA)
Hematology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

NO983285A 1996-01-17 1998-07-16 Pyrido-1,2,4-tiadiazin- og pyrido-1,4-tiazinderivater, deres fremstilling og anvendelse NO983285L (no)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
DK4296		1996-01-17
DK24796		1996-03-05
DK24696		1996-03-05
DK24996		1996-03-05
DK24896		1996-03-05
PCT/DK1997/000018 WO1997026264A1 (en)	1996-01-17	1997-01-16	Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives, their preparation and use

Publications (2)

Publication Number	Publication Date
NO983285D0 NO983285D0 (no)	1998-07-16
NO983285L true NO983285L (no)	1998-09-16

Family

ID=27512741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO983285A NO983285L (no)	1996-01-17	1998-07-16	Pyrido-1,2,4-tiadiazin- og pyrido-1,4-tiazinderivater, deres fremstilling og anvendelse

Country Status (16)

Country	Link
US (1)	US5792764A (de)
EP (1)	EP0877748B1 (de)
JP (1)	JP2000503651A (de)
KR (1)	KR19990077320A (de)
CN (1)	CN1208418A (de)
AT (1)	ATE281460T1 (de)
AU (1)	AU727905B2 (de)
BR (1)	BR9707004A (de)
CA (1)	CA2241565A1 (de)
CZ (1)	CZ220598A3 (de)
DE (1)	DE69731458T2 (de)
IL (1)	IL125072A (de)
NO (1)	NO983285L (de)
PL (1)	PL327927A1 (de)
RU (1)	RU2193564C2 (de)
WO (1)	WO1997026264A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6329368B1 (en) *	1997-05-09	2001-12-11	The Regents Of The University Of California	Endocrine modulation with positive modulators of AMPA type glutamate receptors
WO1999032495A1 (en) *	1997-12-19	1999-07-01	Novo Nordisk A/S	Pyrido 1,2,4-thiadiazine derivatives, their preparation and use
WO2002000222A1 (en) *	2000-06-26	2002-01-03	Novo Nordisk A/S	Use of potassium channel agonists for the treatment of cancer
WO2003045955A1 (en) *	2001-11-30	2003-06-05	Novo Nordisk A/S	Use of selective potassium channel openers
AU2002342600A1 (en) *	2001-11-30	2003-06-10	Novo Nordisk A/S	Use of selective potassium channel openers
US20030109519A1 (en) *	2001-11-30	2003-06-12	Jeppe Sturis	Use of selective potassium channel openers
WO2003105896A1 (en) *	2002-06-14	2003-12-24	Novo Nordisk A/S	Combined use of a modulator of cd3 and a beta cell resting compound
WO2013191984A1 (en) *	2012-06-21	2013-12-27	Boehringer Ingelheim International Gmbh	Fused thiazin-3-ones as kca3.1 inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1368948A (en) *	1970-11-11	1974-10-02	Manuf Prod Pharma	Pyridine derivatives
FR2650589A1 (fr) *	1989-08-04	1991-02-08	Esteve Labor Dr	Derives benzothiaziniques, leur preparation et leurs applications comme medicaments ou comme intermediaires de synthese de medicaments
FR2703051B1 (fr) *	1993-03-26	1995-04-28	Adir	Nouvelles pyridothiadiazines, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.

1997
- 1997-01-16 CN CN97191748A patent/CN1208418A/zh active Pending
- 1997-01-16 KR KR1019980705467A patent/KR19990077320A/ko not_active Ceased
- 1997-01-16 EP EP97900933A patent/EP0877748B1/de not_active Expired - Lifetime
- 1997-01-16 RU RU98115386/04A patent/RU2193564C2/ru active
- 1997-01-16 CA CA002241565A patent/CA2241565A1/en not_active Abandoned
- 1997-01-16 CZ CZ982205A patent/CZ220598A3/cs unknown
- 1997-01-16 AT AT97900933T patent/ATE281460T1/de not_active IP Right Cessation
- 1997-01-16 BR BR9707004A patent/BR9707004A/pt unknown
- 1997-01-16 DE DE69731458T patent/DE69731458T2/de not_active Expired - Lifetime
- 1997-01-16 JP JP9525608A patent/JP2000503651A/ja not_active Ceased
- 1997-01-16 PL PL97327927A patent/PL327927A1/xx unknown
- 1997-01-16 WO PCT/DK1997/000018 patent/WO1997026264A1/en not_active Ceased
- 1997-01-16 IL IL12507297A patent/IL125072A/en not_active IP Right Cessation
- 1997-01-16 AU AU14370/97A patent/AU727905B2/en not_active Ceased
- 1997-01-17 US US08/785,435 patent/US5792764A/en not_active Expired - Lifetime
1998
- 1998-07-16 NO NO983285A patent/NO983285L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN1208418A (zh)	1999-02-17
AU1437097A (en)	1997-08-11
NO983285D0 (no)	1998-07-16
IL125072A (en)	2002-12-01
BR9707004A (pt)	1999-07-20
PL327927A1 (en)	1999-01-04
RU2193564C2 (ru)	2002-11-27
EP0877748B1 (de)	2004-11-03
WO1997026264A1 (en)	1997-07-24
DE69731458D1 (de)	2004-12-09
JP2000503651A (ja)	2000-03-28
ATE281460T1 (de)	2004-11-15
CA2241565A1 (en)	1997-07-24
KR19990077320A (ko)	1999-10-25
CZ220598A3 (cs)	1998-12-16
EP0877748A1 (de)	1998-11-18
DE69731458T2 (de)	2005-12-22
US5792764A (en)	1998-08-11
AU727905B2 (en)	2001-01-04
IL125072A0 (en)	1999-01-26

Legal Events

Date	Code	Title	Description
2003-03-31	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
PT1140945E (pt)	2003-10-31	Derivados 1 2 4 tiadiazina fundidos a sua preparacao e a sua utilizacao
IL116122A0 (en)	1996-01-31	Intermediates to heterocyclic-cyclic amine derivatives
NO985979D0 (no)	1998-12-18	1,2,4-benzotiadiazinderivater, deres fremstilling og anvendelse
NO995431D0 (no)	1999-11-05	Substituerte 3,3-diamino-2-propennitriler, deres fremstilling og anvendelse
NO178397C (no)	1996-03-20	Substituerte 1,2,3,4-tetrahydrocyklopent[bÅindoler, 1,2,3,3a,4,8a-heksahydrocyklopent[bÅindoler og beslektede forbindelser, mellomprodukter og deres bruk som medikamenter
NO983285D0 (no)	1998-07-16	Pyrido-1,2,4-tiadiazin- og pyrido-1,4-tiazinderivater, deres fremstilling og anvendelse
ES2194102T3 (es)	2003-11-16	Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
NO306554B1 (no)	1999-11-22	Syklopentadienylmagnesium-broforbindelser, fremgangsmåte for deres fremstilling, og deres anvendelse for fremstilling av metallocenene
DE58905079D1 (de)	1993-09-09	Neue alpha-aminocarbonsaeure-derivate, ihre herstellung und verwendung.
BG105247A (en)	2001-11-30	N-substituted azabicycloheptane derivatives, production and use thereof
DK0521766T3 (da)	1995-02-20	Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater
DK0555283T3 (da)	1995-07-03	Mellemprodukter ved fremstillingen af 4,5-difluoranthranilinsyre
DE59905342D1 (de)	2003-06-05	N-substituierte azabicycloheptan-derivate, ihre herstellung und verwendung
UA66755C2 (en)	2004-06-15	Derivatives of condensed 1,2,4-thiadiazine, a method for the preparation thereof, pharmaceutical composition and a method for treatment or prevention of endocrine system diseases