NO983525L - Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler - Google Patents

Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler

Info

Publication number: NO983525L
Authority: NO; Norway
Prior art keywords: atoms; dihydrobenzofuran; branched; inflammatory agents; straight
Prior art date: 1996-02-01

Application number

NO983525A

Other languages

English (en)

Norwegian (no)

Other versions

NO983525D0 (no

Inventor

Michael Wiard Scherz

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-01

Filing date

1998-07-31

Publication date

1998-09-30

1998-07-31 Application filed by Procter & Gamble filed Critical Procter & Gamble

1998-07-31 Publication of NO983525D0 publication Critical patent/NO983525D0/no

1998-09-30 Publication of NO983525L publication Critical patent/NO983525L/no

Links

150000001875 compounds Chemical class 0.000 title abstract 4
HBEDSQVIWPRPAY-UHFFFAOYSA-N 2,3-dihydrobenzofuran Chemical compound C1=CC=C2OCCC2=C1 HBEDSQVIWPRPAY-UHFFFAOYSA-N 0.000 title 2
229940121363 anti-inflammatory agent Drugs 0.000 title 1
239000002260 anti-inflammatory agent Substances 0.000 title 1
125000004429 atom Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
206010061218 Inflammation Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)

NO983525A 1996-02-01 1998-07-31 Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler NO983525L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/595,158 US5684041A (en)	1996-02-01	1996-02-01	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
PCT/US1997/001308 WO1997028143A1 (en)	1996-02-01	1997-01-30	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Publications (2)

Publication Number	Publication Date
NO983525D0 NO983525D0 (no)	1998-07-31
NO983525L true NO983525L (no)	1998-09-30

Family

ID=24381988

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO983525A NO983525L (no)	1996-02-01	1998-07-31	Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler

Country Status (16)

Country	Link
US (1)	US5684041A (de)
EP (1)	EP0879231B1 (de)
JP (1)	JP3095421B2 (de)
KR (1)	KR100350920B1 (de)
CN (1)	CN1097588C (de)
AT (1)	ATE277031T1 (de)
AU (1)	AU730319B2 (de)
BR (1)	BR9707250A (de)
CA (1)	CA2244194C (de)
DE (1)	DE69730817T2 (de)
DK (1)	DK0879231T3 (de)
ES (1)	ES2229331T3 (de)
MX (1)	MX9806251A (de)
NO (1)	NO983525L (de)
NZ (1)	NZ331618A (de)
WO (1)	WO1997028143A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0516948U (ja) *	1991-08-16	1993-03-02	湯浅起市郎	金属製板体の吊子構造
CA2450073C (en)	2001-07-25	2017-08-29	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
US7465815B2 (en)	2003-06-26	2008-12-16	Takeda Pharmaceutical Company Limited	Cannabinoid receptor modulator
GB0322016D0 (en) *	2003-09-19	2003-10-22	Merck Sharp & Dohme	New compounds
US20050261347A1 (en) *	2003-10-24	2005-11-24	Wyeth	Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7435837B2 (en) *	2003-10-24	2008-10-14	Wyeth	Dihydrobenzofuranyl alkanamine derivatives and methods for using same
EP2671508B1 (de)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-Informatiksystem
JP2010503710A (ja)	2006-09-18	2010-02-04	ラプトールファーマシューティカルインコーポレイテッド	受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates
EP3768266A4 (de) *	2018-03-20	2021-12-22	Merck Sharp & Dohme Corp.	Oxo-tetrahydro-isochinolin-carboxylsäuren als sting-inhibitoren

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3252999A (en) *	1963-11-01	1966-05-24	American Home Prod	Derivatives of 5-amino-2, 3-dihydro-2-methyl benzofuran
US3963717A (en) *	1975-03-10	1976-06-15	Sandoz, Inc.	Tricyclic furo-quinazolinones
JPS6019305B2 (ja) *	1976-07-02	1985-05-15	ウェルファイド株式会社	ジヒドロベンゾフラン誘導体
CH632268A5 (de) *	1977-01-14	1982-09-30	Sandoz Ag	Verfahren zur herstellung von neuen heterocyclylaminoderivaten.
IT1093805B (it) *	1978-01-31	1985-07-26	Erba Carlo Spa	Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
US4470440A (en) *	1982-09-30	1984-09-11	Thor Harry A	Impact producing tool
JPS60108846A (ja) *	1983-11-18	1985-06-14	Konishiroku Photo Ind Co Ltd	ハロゲン化銀写真感光材料
AU556949B2 (en) *	1984-10-25	1986-11-27	Fmc Corporation	Pyrozoline insecticides
US4767779A (en) *	1985-09-24	1988-08-30	Fmc Corporation	Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them
IT206464Z2 (it) *	1986-02-27	1987-08-10	Alfa Romeo Spa	Impianto di scarico per un motore a c.i..
DE3777366D1 (de) *	1986-12-27	1992-04-16	Takeda Chemical Industries Ltd	2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung.
US4849428A (en) *	1987-11-23	1989-07-18	The Procter & Gamble Company	Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use
DE3810080A1 (de) *	1988-03-25	1989-10-05	Bayer Ag	Trisubstituierte 1,3,5-triazin-2,4,6-trione
JP2855341B2 (ja) *	1988-06-10	1999-02-10	武田薬品工業株式会社	新規２―置換クマラン誘導体
US4966907A (en) *	1988-08-12	1990-10-30	Merck & Co., Inc.	6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
US4975457A (en) *	1989-09-25	1990-12-04	Merck & Co., Inc.	Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
EP0458970A4 (en) *	1989-11-17	1992-05-13	Meiji Milk Products Company Limited	Benzofuran derivative, process for preparing the same, and pharmaceutical comprising the same as active ingredient
US5091533A (en) *	1990-03-12	1992-02-25	Merck Frosst Canada, Inc.	5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
CA2078126A1 (en) *	1990-03-27	1991-09-28	Jerry Leroy Adams	5-lipoxygenase inhibitors
WO1992012144A1 (en) *	1990-12-28	1992-07-23	Teijin Limited	Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same
AU2390892A (en) *	1991-08-08	1993-03-02	Yamanouchi Pharmaceutical Co., Ltd.	Urea derivative
FR2682381B1 (fr) *	1991-10-10	1995-04-07	Rhone Poulenc Rorer Sa	Derives de benzodiazepine, leur preparation et les medicaments les contenant.
US5684002A (en) *	1994-09-07	1997-11-04	The Procter & Gamble Company	Dihydorbenzofuran and related compounds useful as anti-inflammatory agents

1996
- 1996-02-01 US US08/595,158 patent/US5684041A/en not_active Expired - Fee Related
1997
- 1997-01-30 WO PCT/US1997/001308 patent/WO1997028143A1/en not_active Ceased
- 1997-01-30 KR KR1019980705951A patent/KR100350920B1/ko not_active Expired - Fee Related
- 1997-01-30 DK DK97904014T patent/DK0879231T3/da active
- 1997-01-30 DE DE69730817T patent/DE69730817T2/de not_active Expired - Fee Related
- 1997-01-30 NZ NZ331618A patent/NZ331618A/xx unknown
- 1997-01-30 AT AT97904014T patent/ATE277031T1/de not_active IP Right Cessation
- 1997-01-30 JP JP09527757A patent/JP3095421B2/ja not_active Expired - Fee Related
- 1997-01-30 EP EP97904014A patent/EP0879231B1/de not_active Expired - Lifetime
- 1997-01-30 BR BR9707250A patent/BR9707250A/pt not_active Application Discontinuation
- 1997-01-30 CN CN97191977A patent/CN1097588C/zh not_active Expired - Fee Related
- 1997-01-30 AU AU18428/97A patent/AU730319B2/en not_active Ceased
- 1997-01-30 CA CA002244194A patent/CA2244194C/en not_active Expired - Fee Related
- 1997-01-30 ES ES97904014T patent/ES2229331T3/es not_active Expired - Lifetime
1998
- 1998-07-31 NO NO983525A patent/NO983525L/no not_active Application Discontinuation
- 1998-08-03 MX MX9806251A patent/MX9806251A/es not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2244194A1 (en)	1997-08-07
NZ331618A (en)	2000-08-25
BR9707250A (pt)	1999-04-06
AU730319B2 (en)	2001-03-01
KR100350920B1 (ko)	2002-11-18
JP3095421B2 (ja)	2000-10-03
CN1210529A (zh)	1999-03-10
WO1997028143A1 (en)	1997-08-07
AU1842897A (en)	1997-08-22
US5684041A (en)	1997-11-04
ES2229331T3 (es)	2005-04-16
NO983525D0 (no)	1998-07-31
DK0879231T3 (da)	2004-12-20
CA2244194C (en)	2003-05-06
JPH11503467A (ja)	1999-03-26
ATE277031T1 (de)	2004-10-15
MX9806251A (es)	1998-11-30
DE69730817D1 (de)	2004-10-28
KR19990082223A (ko)	1999-11-25
EP0879231B1 (de)	2004-09-22
EP0879231A1 (de)	1998-11-25
DE69730817T2 (de)	2005-02-03
CN1097588C (zh)	2003-01-01

Legal Events

Date	Code	Title	Description
2001-09-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO983529D0 (no)	1998-07-31	Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
DK0779886T3 (da)	2002-03-11	Dihydrobenzofuran og beslægtede forbindelser, der er anvendelige som antiinflammatoriske midler
NO983525D0 (no)	1998-07-31	Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
NO985679D0 (no)	1998-12-04	Dihydrobenzopyran og beslektede forbindelser nyttige som anti-inflammasjonsmidler
NO983531L (no)	1998-09-28	Dihydrobenzofuranforbindelser anvendelig som anti-inflammatoriske midler
DK0904270T3 (da)	2003-12-01	Dihydrobenzofuran og beslægtede forbindelser anvendelige som antiinflammatoriske midler
NO983528L (no)	1998-09-28	Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
MX9806247A (es)	1998-11-30	Dihidrobenzofurano y compuestos relacionados utiles como agentes antiinflamatorios.
CA2244245A1 (en)	1997-08-07	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents