NO984325L - 2-(3H)-oksazolon-derivater og deres anvendelse som COX-2-inhibitorer - Google Patents

2-(3H)-oksazolon-derivater og deres anvendelse som COX-2-inhibitorer

Info

Publication number
NO984325L
NO984325L NO984325A NO984325A NO984325L NO 984325 L NO984325 L NO 984325L NO 984325 A NO984325 A NO 984325A NO 984325 A NO984325 A NO 984325A NO 984325 L NO984325 L NO 984325L
Authority
NO
Norway
Prior art keywords
cox
inhibitors
oxazolone derivatives
oxazolone
derivatives
Prior art date
Application number
NO984325A
Other languages
English (en)
Other versions
NO984325D0 (no
NO311761B1 (no
Inventor
Carles Puig Duran
Ferrsn Pujol Noguera
Dolors Fernandez Forner
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8294266&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO984325(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Publication of NO984325D0 publication Critical patent/NO984325D0/no
Publication of NO984325L publication Critical patent/NO984325L/no
Publication of NO311761B1 publication Critical patent/NO311761B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/38—One oxygen atom attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19984325A 1996-03-21 1998-09-17 2-(3H)-Oksazolonderivater og deres anvendelse NO311761B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009600685A ES2125161B1 (es) 1996-03-21 1996-03-21 Nuevos derivados de 2-(3h)-oxazolona.
PCT/EP1997/001386 WO1997034882A1 (en) 1996-03-21 1997-03-19 2-(3h)-oxazolone derivatives and their use as cox-2 inhibitors

Publications (3)

Publication Number Publication Date
NO984325D0 NO984325D0 (no) 1998-09-17
NO984325L true NO984325L (no) 1998-11-23
NO311761B1 NO311761B1 (no) 2002-01-21

Family

ID=8294266

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984325A NO311761B1 (no) 1996-03-21 1998-09-17 2-(3H)-Oksazolonderivater og deres anvendelse

Country Status (29)

Country Link
US (1) US6869968B1 (no)
EP (1) EP0888316B1 (no)
JP (1) JP3810091B2 (no)
KR (1) KR100496395B1 (no)
CN (1) CN1110488C (no)
AR (1) AR006340A1 (no)
AT (1) ATE197294T1 (no)
AU (1) AU713811B2 (no)
BR (1) BR9708141A (no)
CA (1) CA2249420A1 (no)
CO (1) CO4780046A1 (no)
CZ (1) CZ294963B6 (no)
DE (1) DE69703437T2 (no)
DK (1) DK0888316T3 (no)
ES (2) ES2125161B1 (no)
GR (1) GR3035096T3 (no)
ID (1) ID16778A (no)
IL (1) IL126206A (no)
NO (1) NO311761B1 (no)
NZ (1) NZ331901A (no)
PE (1) PE42898A1 (no)
PL (1) PL188722B1 (no)
PT (1) PT888316E (no)
RU (1) RU2194043C2 (no)
TW (1) TW426674B (no)
UA (1) UA52645C2 (no)
UY (1) UY24499A1 (no)
WO (1) WO1997034882A1 (no)
ZA (1) ZA972203B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125161B1 (es) 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
FR2753449B1 (fr) * 1996-09-13 1998-12-04 Union Pharma Scient Appl Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
ES2131015B1 (es) * 1997-09-12 2000-03-01 Almirall Prodesfarma Sa Nuevos derivados de 2-(3h)-oxazolona, procedimientos para su preparacion y su empleo en composiciones farmaceuticas.
ES2168895A1 (es) * 1999-03-26 2002-06-16 Almirall Prodesfarma Sa Derivados de 2-fenilpiran-4-ona.
ES2154561B1 (es) * 1998-09-25 2001-12-01 Almirall Prodesfarma Sa Derivados de 2-fenilpiran-4-ona.
CO5261556A1 (es) 1999-12-08 2003-03-31 Pharmacia Corp Composiciones inhibidoras de ciclooxigenasa-2 que tiene rapido acceso de efecto terapeutico
JP2003523958A (ja) 1999-12-23 2003-08-12 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化されたシクロオキシゲナーゼ−２の阻害剤、組成物ならびに使用法
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
JP2005535642A (ja) 2002-06-28 2005-11-24 ニトロメッド インコーポレーティッド オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
ES2215474B1 (es) 2002-12-24 2005-12-16 J. URIACH & CIA S.A. Nuevos derivados de fosforamida.
ES2213485B1 (es) 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
PT1534305E (pt) 2003-05-07 2007-02-28 Osteologix As Tratamento de afecções cartilagineas / osseas com sais de estroncio hidrosoluveis
CN1309717C (zh) * 2003-06-03 2007-04-11 李小虎 4－芳基－5h－噻吩－2－酮衍生物、其制法和用途
RU2270673C1 (ru) * 2004-08-17 2006-02-27 Государственное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" (ГОУ ВПО СибГМУ) Способ реабилитации больных после операции на щитовидной железе
CN101626787A (zh) * 2007-01-19 2010-01-13 马林克罗特公司 诊断的和治疗的环氧合酶-2结合配体
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3578671A (en) * 1967-11-06 1971-05-11 Wyeth John & Brother Ltd Oxazoles
US4632930A (en) * 1984-11-30 1986-12-30 E. I. Du Pont De Nemours And Company Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives
ZW19786A1 (en) * 1985-10-17 1988-05-18 Hoffmann La Roche Heterocyclic compounds
US4866182A (en) 1988-02-18 1989-09-12 Merrell Dow Pharmaceuticals Inc. Cardiotonic alkanoyl and aroyl oxazolones
US5380738A (en) 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
DE4435547A1 (de) 1994-10-05 1996-04-11 Bayer Ag Sulfonylaminocarbonyltriazolinone mit über Sauerstoff und Schwefel gebundenen Substituenten
JP2636819B2 (ja) 1994-12-20 1997-07-30 日本たばこ産業株式会社 オキサゾール系複素環式芳香族化合物
ES2125161B1 (es) 1996-03-21 1999-11-16 Grupo Farmaceutico Almirall S Nuevos derivados de 2-(3h)-oxazolona.
FR2753449B1 (fr) 1996-09-13 1998-12-04 Union Pharma Scient Appl Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique

Also Published As

Publication number Publication date
CN1218459A (zh) 1999-06-02
TW426674B (en) 2001-03-21
KR100496395B1 (ko) 2005-09-27
GR3035096T3 (en) 2001-03-30
DK0888316T3 (da) 2000-11-27
CN1110488C (zh) 2003-06-04
US6869968B1 (en) 2005-03-22
ES2125161B1 (es) 1999-11-16
WO1997034882A1 (en) 1997-09-25
DE69703437D1 (de) 2000-12-07
CZ297998A3 (cs) 1999-02-17
JP3810091B2 (ja) 2006-08-16
PL328915A1 (en) 1999-03-01
HK1015371A1 (en) 1999-10-15
CZ294963B6 (cs) 2005-04-13
ID16778A (id) 1997-11-13
CA2249420A1 (en) 1997-09-25
BR9708141A (pt) 1999-07-27
AU713811B2 (en) 1999-12-09
RU2194043C2 (ru) 2002-12-10
NO984325D0 (no) 1998-09-17
NZ331901A (en) 1999-10-28
CO4780046A1 (es) 1999-05-26
NO311761B1 (no) 2002-01-21
IL126206A (en) 2001-06-14
UY24499A1 (es) 1997-04-02
EP0888316B1 (en) 2000-11-02
AU2289397A (en) 1997-10-10
EP0888316A1 (en) 1999-01-07
UA52645C2 (uk) 2003-01-15
PT888316E (pt) 2001-02-28
ZA972203B (en) 1997-09-25
PL188722B1 (pl) 2005-04-29
DE69703437T2 (de) 2001-03-08
JP2000506876A (ja) 2000-06-06
MX9701944A (es) 1998-06-30
ES2151254T3 (es) 2000-12-16
IL126206A0 (en) 1999-05-09
PE42898A1 (es) 1998-08-12
ATE197294T1 (de) 2000-11-15
ES2125161A1 (es) 1999-02-16
KR20000064727A (ko) 2000-11-06
AR006340A1 (es) 1999-08-25

Similar Documents

Publication Publication Date Title
NO20013452D0 (no) Benzoheterocykler og deres anvendelse som MEK-inhibitorer
DK0888316T3 (da) 2-(3H)-oxazolonderivater og deres anvendelse som cox-2 inhibitorer
NO991922D0 (no) Heteroarylsuccinamider og deres anvendelse som metalloproteinaseinhibitorer
NO20001323D0 (no) Dipeptid-apoptose inhibitorer og deres anvendelse
EE9900290A (et) 3-heterotsüklüül-asendatud bensoüülderivaadid
DK1223933T3 (da) 5-leddet derivater af heterocyklusser og deres anvendelse som monoaminoxidaseinhibitorer
DK1375503T3 (da) Dioxinoderivater og deres anvendelse som dopaminagonister
DK1475377T3 (da) Indol-derivater og deres anvendelse som inhibitorer for phosphodiesterase 4
DK0811006T3 (da) Benzopyranholdige forbindelser og fremgangsmåde til deres anvendelse
NO996491D0 (no) 4-brom- eller 4-iod-fenylaminobenzhydroksamsyre-derivater og deres anvendelse som MEK-inhibitorer
ATE251612T1 (de) 6-phenylpyridyl-2-amin-derivate verwendbar als nos-inhibitoren
NO954369D0 (no) Oksazolidindionderivater, deres fremstilling og anvendelse
IS6385A (is) Ný notkun og nýjar N-asabísýkló-amíð afleiður
DK0906292T3 (da) Triazolylmercaptider og deres anvendelse som mikrobicider
NO992492D0 (no) Benzamidoaldehyder og deres anvendelse som cystein-protease-inhibitorer
DE69906311D1 (de) Diarylbenzopyranderivate als cyclooxygenase-2-inhibitoren
NO984761D0 (no) Aminoisokinoliner og aminotienopyridinderivater og deres anvendelse som antiinflammatoriske midler
ATE202078T1 (de) 2-(4-substituierte)-benzylamino-2-methyl- propanamid-derivate
NO995513D0 (no) N-triazolyl-2-indolkarboksamider og deres anvendelse som CCK-A agonister
NO994510L (no) Substituerte isokinolin-derivater og deres anvendelse som antikonvulsanter
NO985307L (no) Distamycinderivater, fremgangsmÕte for deres fremstilling, og deres anvende
DK1150996T3 (da) Nye amidinobenzylaminderivater og deres anvendelse som thrombin-inhibitorer
NO20013085D0 (no) Fosfororganiske forbindelser og deres anvendelse
NO20001718D0 (no) Benzen-fusjonerte heterocykliske derivater og anvendelse derav
NO984921D0 (no) Tienopyridinderivater og deres anvendelse