NO985300L - FremgangsmÕte for spalting av racemisk ketamin - Google Patents

FremgangsmÕte for spalting av racemisk ketamin

Info

Publication number: NO985300L
Authority: NO; Norway
Prior art keywords: pct; cleavage; racemic ketamine; date nov; ketamine
Prior art date: 1996-05-15

Application number

NO985300A

Other languages

English (en)

Other versions

NO985300D0 (no

NO311565B1 (no

Inventor

Klaus Steiner

Stefan Gangkofner

Jean-Marie Grunenwald

Original Assignee

Uetikon Chemie Gmbh

Goedecke Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-15

Filing date

1998-11-13

Publication date

1998-11-13

1998-11-13 Application filed by Uetikon Chemie Gmbh, Goedecke Ag filed Critical Uetikon Chemie Gmbh

1998-11-13 Publication of NO985300D0 publication Critical patent/NO985300D0/no

1998-11-13 Publication of NO985300L publication Critical patent/NO985300L/no

2001-12-10 Publication of NO311565B1 publication Critical patent/NO311565B1/no

Links

YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 title abstract 3
229960003299 ketamine Drugs 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000003776 cleavage reaction Methods 0.000 title 1
230000007017 scission Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)
Pyrrole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

NO19985300A 1996-05-15 1998-11-13 Fremgangsmåte for spalting av racemisk ketamin NO311565B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19619665A DE19619665C2 (de)	1996-05-15	1996-05-15	Racemattrennung von Ketamin
PCT/EP1997/002360 WO1997043244A1 (de)	1996-05-15	1997-05-07	Racemattrennung von ketamin

Publications (3)

Publication Number	Publication Date
NO985300D0 NO985300D0 (no)	1998-11-13
NO985300L true NO985300L (no)	1998-11-13
NO311565B1 NO311565B1 (no)	2001-12-10

Family

ID=7794445

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19985300A NO311565B1 (no)	1996-05-15	1998-11-13	Fremgangsmåte for spalting av racemisk ketamin

Country Status (20)

Country	Link
US (1)	US6040479A (no)
EP (1)	EP0918744B1 (no)
JP (1)	JP4151988B2 (no)
AT (1)	ATE272606T1 (no)
AU (1)	AU727528B2 (no)
CA (1)	CA2253575C (no)
CZ (1)	CZ293546B6 (no)
DE (2)	DE19619665C2 (no)
DK (1)	DK0918744T3 (no)
EE (1)	EE03436B1 (no)
ES (1)	ES2224247T3 (no)
HU (1)	HU225773B1 (no)
IL (1)	IL127026A (no)
NO (1)	NO311565B1 (no)
PL (1)	PL187625B1 (no)
PT (1)	PT918744E (no)
SK (1)	SK282699B6 (no)
TR (1)	TR199802317T2 (no)
WO (1)	WO1997043244A1 (no)
ZA (1)	ZA974216B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0002693B8 (pt) *	2000-06-19	2021-05-25	Cristalia Produtos Quim Farmaceuticos Ltda	processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis
PE20200404A1 (es)	2013-03-15	2020-02-26	Janssen Pharmaceutica Nv	Composicion farmaceutica de clorhidrato de s-ketamina
SI3043785T1 (sl)	2013-09-13	2022-02-28	National University Corporation Chiba University	Uporaba R-ketamina in njegove soli kot farmacevtska sredstva
CN106714789A (zh)	2014-08-13	2017-05-24	詹森药业有限公司	用于治疗抑郁症的方法
CN107208133A (zh)	2014-09-15	2017-09-26	詹森药业有限公司	用于治疗抑郁症的Val66Met (SNPrs6265)基因型特异性给药方案和方法
US20160332962A1 (en) *	2015-05-13	2016-11-17	Janssen Pharmaceutica Nv	(s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
US20190240184A1 (en)	2016-10-27	2019-08-08	National University Corporation Chiba University	Pharmaceutical applications for (s)-norketamine and salts thereof
US20200009081A1 (en)	2017-09-13	2020-01-09	Janssen Pharmaceutica N.V.	Delivery Of Esketamine For The Treatment Of Depression
WO2019065900A1 (ja)	2017-09-27	2019-04-04	国立大学法人千葉大学	神経変性疾患あるいは認知機能障害の予防または治療剤としてのｒ－ケタミンおよびその誘導体
MX2020006650A (es)	2017-12-22	2020-11-06	Janssen Pharmaceuticals Inc	Esketamina para el tratamiento de la depresión.
JP7548669B2 (ja)	2018-02-15	2024-09-10	国立大学法人千葉大学	炎症性疾患若しくは骨疾患の予防又は治療剤及び医薬組成物
AU2019262197B2 (en)	2018-05-04	2024-12-19	Perception Neuroscience, Inc.	Methods of treating substance abuse
US20220110889A1 (en)	2018-12-27	2022-04-14	National University Corporation Chiba University	R-ketamine and derivative thereof as prophylactic or therapeutic agent for neurodevelopmental disorder
MX2021010683A (es)	2019-03-05	2021-12-10	Janssen Pharmaceuticals Inc	Esketamina para el tratamiento de la depresión.
EP3956300A1 (en) *	2019-04-16	2022-02-23	Janssen Pharmaceutica NV	Synthetic methods of preparing esketamine
CN112125816A (zh) *	2020-03-17	2020-12-25	国药集团工业有限公司	一种氯胺酮、其衍生物或其盐的消旋化方法
CN112409195A (zh) *	2020-03-17	2021-02-26	国药集团工业有限公司	一种(s)-氯胺酮盐酸盐的制备方法及其中间体、其晶型
WO2024145288A2 (en) *	2022-12-28	2024-07-04	Perception Neuroscience, Inc.	Methods of administering r-ketamine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH535201A (de) *	1969-12-19	1973-03-31	Bristol Myers Co	Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren

1996
- 1996-05-15 DE DE19619665A patent/DE19619665C2/de not_active Expired - Lifetime
1997
- 1997-05-07 IL IL12702697A patent/IL127026A/en not_active IP Right Cessation
- 1997-05-07 EP EP97923022A patent/EP0918744B1/de not_active Expired - Lifetime
- 1997-05-07 PT PT97923022T patent/PT918744E/pt unknown
- 1997-05-07 CA CA002253575A patent/CA2253575C/en not_active Expired - Lifetime
- 1997-05-07 TR TR1998/02317T patent/TR199802317T2/xx unknown
- 1997-05-07 EE EE9800394A patent/EE03436B1/xx unknown
- 1997-05-07 ES ES97923022T patent/ES2224247T3/es not_active Expired - Lifetime
- 1997-05-07 JP JP54048797A patent/JP4151988B2/ja not_active Expired - Lifetime
- 1997-05-07 AU AU28943/97A patent/AU727528B2/en not_active Expired
- 1997-05-07 DK DK97923022T patent/DK0918744T3/da active
- 1997-05-07 WO PCT/EP1997/002360 patent/WO1997043244A1/de not_active Ceased
- 1997-05-07 DE DE59711834T patent/DE59711834D1/de not_active Expired - Lifetime
- 1997-05-07 HU HU9903085A patent/HU225773B1/hu unknown
- 1997-05-07 AT AT97923022T patent/ATE272606T1/de active
- 1997-05-07 SK SK1529-98A patent/SK282699B6/sk not_active IP Right Cessation
- 1997-05-07 CZ CZ19983558A patent/CZ293546B6/cs not_active IP Right Cessation
- 1997-05-07 US US09/180,530 patent/US6040479A/en not_active Expired - Lifetime
- 1997-05-07 PL PL97329743A patent/PL187625B1/pl unknown
- 1997-05-15 ZA ZA9704216A patent/ZA974216B/xx unknown
1998
- 1998-11-13 NO NO19985300A patent/NO311565B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0918744T3 (da)	2004-12-06
ES2224247T3 (es)	2005-03-01
HUP9903085A1 (hu)	2000-04-28
CA2253575A1 (en)	1997-11-20
JP4151988B2 (ja)	2008-09-17
NO985300D0 (no)	1998-11-13
EE9800394A (et)	1999-06-15
WO1997043244A1 (de)	1997-11-20
CA2253575C (en)	2005-11-29
HU225773B1 (en)	2007-08-28
JP2000510135A (ja)	2000-08-08
NO311565B1 (no)	2001-12-10
DE19619665A1 (de)	1997-11-20
US6040479A (en)	2000-03-21
SK282699B6 (sk)	2002-11-06
DE19619665C2 (de)	2001-03-08
AU727528B2 (en)	2000-12-14
PL187625B1 (pl)	2004-08-31
IL127026A0 (en)	1999-09-22
EP0918744B1 (de)	2004-08-04
PL329743A1 (en)	1999-04-12
SK152998A3 (en)	1999-07-12
EP0918744A1 (de)	1999-06-02
DE59711834D1 (de)	2004-09-09
CZ293546B6 (cs)	2004-06-16
EE03436B1 (et)	2001-06-15
IL127026A (en)	2004-02-19
CZ355898A3 (cs)	1999-04-14
HUP9903085A3 (en)	2000-05-29
AU2894397A (en)	1997-12-05
ZA974216B (en)	1997-12-10
ATE272606T1 (de)	2004-08-15
PT918744E (pt)	2004-10-29
TR199802317T2 (xx)	1999-02-22

Legal Events

Date	Code	Title	Description
2017-05-15	MK1K	Patent expired

Publication	Publication Date	Title
NO985300L (no)	1998-11-13	FremgangsmÕte for spalting av racemisk ketamin
DE69710182D1 (de)	2002-03-14	Verwendung von tetrahydrobetacarbolin-derivaten zur vorbeugung der metastasenbildung
ES2146097T3 (es)	2000-07-16	Composiciones acuosas termoendurecibles.
DK1007092T3 (da)	2006-10-02	En fremgangsmåde til inhibering af komplementaktivering via det alternative forlöb
ATE219064T1 (de)	2002-06-15	Piperazinderivative als tachykinin antagonisten
ES2172657T3 (es)	2002-10-01	Inhibidores de trombina.
BG101687A (bg)	1998-02-27	Заместени азетидин-2-они за лечение на атеросклероза
BR9707834A (pt)	2000-01-04	Uso de conservante de madeira, e, bandagem para pós-proteção de madeira
DK0941221T3 (da)	2003-06-10	Substituerede dihydrobenzofuraner som PDE-inhibitorer
ES2171969T3 (es)	2002-09-16	Combinacion fusible de estabilizadores.
DK0825983T3 (da)	2001-12-17	Fremgangsmåde til fremstilling af 2,2'-bipyrrolyl-pyrromethen-derivater (prodigiosiner)
TR199800243T1 (xx)	1998-06-22	Prolil endopeptidaz inhibit�rleri.
NO991633D0 (no)	1999-04-06	FremgangsmÕte ved biotransformasjon av kolkisinforbindelser til de tilsvarende 3-glykosyl-derivater
DE69712878D1 (en)	2002-07-04	Phosphatasemodulator
SG141217A1 (en)	2008-04-28	Non-homogeneous systems for the resolution of enantiomeric mixtures
DK0900218T3 (da)	2002-09-02	Heterocykliske forbindelser
ATE209493T1 (de)	2001-12-15	Verwendung von aspirochlorine oder dessen derivaten zur immunsuppression
ES2154457T3 (es)	2001-04-01	Derivados de ciclohexadieno sustituidos con dimetilo.
ES2172699T3 (es)	2002-10-01	Procedimiento para la preparacion de prostaglandina e1.
ID18481A (id)	1998-04-09	2-(3,5-difluorofenil)-3-(4-metilsulfonil)fenil)-2-siklopenten-1-on yang berguna sebagai inhibitor cox-2