NO985683D0 - Fragmenter av leptin (ob protein) - Google Patents

Fragmenter av leptin (ob protein)

Info

Publication number
NO985683D0
NO985683D0 NO985683A NO985683A NO985683D0 NO 985683 D0 NO985683 D0 NO 985683D0 NO 985683 A NO985683 A NO 985683A NO 985683 A NO985683 A NO 985683A NO 985683 D0 NO985683 D0 NO 985683D0
Authority
NO
Norway
Prior art keywords
leptin
fragments
protein
Prior art date
Application number
NO985683A
Other languages
English (en)
Other versions
NO985683L (no
Inventor
Kamal A Al-Barazanji
Jonathan Robert Sanders Arch
Patrick Camilleri
William Arthur Neville
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9611775.9A external-priority patent/GB9611775D0/en
Priority claimed from GBGB9618540.0A external-priority patent/GB9618540D0/en
Priority claimed from GBGB9703493.8A external-priority patent/GB9703493D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO985683L publication Critical patent/NO985683L/no
Publication of NO985683D0 publication Critical patent/NO985683D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO985683A 1996-06-06 1998-12-04 Fragmenter av leptin (ob protein) NO985683D0 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9611775.9A GB9611775D0 (en) 1996-06-06 1996-06-06 Novel compounds
GBGB9618540.0A GB9618540D0 (en) 1996-09-05 1996-09-05 Novel compounds
GBGB9703493.8A GB9703493D0 (en) 1997-02-20 1997-02-20 Novel compounds
PCT/EP1997/002968 WO1997046585A2 (en) 1996-06-06 1997-06-04 Fragments of leptin (ob protein)

Publications (2)

Publication Number Publication Date
NO985683L NO985683L (no) 1998-12-04
NO985683D0 true NO985683D0 (no) 1998-12-04

Family

ID=27268305

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985683A NO985683D0 (no) 1996-06-06 1998-12-04 Fragmenter av leptin (ob protein)

Country Status (15)

Country Link
EP (1) EP0912609A2 (no)
JP (1) JP2000512137A (no)
KR (1) KR20000016402A (no)
CN (1) CN1221426A (no)
AR (1) AR008765A1 (no)
AU (1) AU3337297A (no)
BR (1) BR9709529A (no)
CA (1) CA2257240A1 (no)
CZ (1) CZ397898A3 (no)
IL (1) IL127153A0 (no)
NO (1) NO985683D0 (no)
NZ (1) NZ332879A (no)
PL (1) PL330361A1 (no)
TR (1) TR199802534T2 (no)
WO (1) WO1997046585A2 (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
WO2000007014A2 (en) 1998-07-28 2000-02-10 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Leptin-mediated gene-induction
US7208572B2 (en) 1998-08-21 2007-04-24 Albany Medical College Leptin-related peptides
US6777388B1 (en) 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
WO2001021647A2 (en) 1999-09-22 2001-03-29 Genset Methods of screening for compounds that modulate the lsr-leptin interaction and their use in the prevention and treatment of obesity-related diseases
JP4756813B2 (ja) 2000-05-22 2011-08-24 フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー（ヴェーイーベー・ヴェーゼットウェー） レセプターを用いた相互作用の捕捉法
PT2219031E (pt) 2001-10-22 2013-05-17 Amgen Inc Uso de leptina para tratamento de lipoatrofia humana e método para determinar predisposição ao referido tratamento
CA2535021A1 (en) 2003-09-08 2005-03-17 Applied Research Systems Ars Holding N.V. Use of insp035 to treat fibrotic disease
EP1718665B1 (en) 2004-02-11 2013-04-10 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
CA2585549A1 (en) 2004-11-18 2006-05-26 Vib Vzw Novel type leptin receptor antagonist
BRPI0606992A2 (pt) 2005-02-11 2009-07-28 Amylin Pharmaceuticals Inc análogo e polipeptìdeos hìbridos de gip com propriedades selecionáveis
US7629315B2 (en) 2005-03-09 2009-12-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Compositions for blocking the inhibitory effect of human CRP on human leptin
BRPI0614649A2 (pt) 2005-08-11 2011-04-12 Amylin Pharmaceuticals Inc polipeptìdeos hìbridos com propriedades selecionáveis
EP2330124B1 (en) 2005-08-11 2015-02-25 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
ES2319048B1 (es) * 2007-06-20 2010-02-10 Universitat De Les Illes Balears Uso de leptina en el tratamiento de alteraciones en los habitos alimentarios.
US8889622B2 (en) 2007-07-25 2014-11-18 Washington University Methods of inhibiting seizure in a subject
GB2451858A (en) * 2007-08-15 2009-02-18 Sergiy Konovchuk Methods of reducing body fat and treating obesity
CN102015668A (zh) 2007-12-05 2011-04-13 阿斯利康(瑞典)有限公司 用作瘦蛋白受体调节剂的哌嗪衍生物及其用途
EA201000926A1 (ru) 2007-12-05 2011-02-28 Астразенека Аб Пиперазины в качестве агентов против ожирения
JP2011522006A (ja) * 2008-06-04 2011-07-28 アストラゼネカ アクチボラグ 新規化合物ｖ
EP2313094A1 (en) * 2008-06-04 2011-04-27 AstraZeneca AB New pyridine derivatives as leptin receptor modulator mimetics
WO2010118384A2 (en) 2009-04-10 2010-10-14 Amylin Pharmaceuticals, Inc. Amylin agonist compounds for estrogen-deficient mammals
WO2011143280A2 (en) * 2010-05-11 2011-11-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Peptide-based inhibitor of interleukin-10 or interferon-gamma signaling
ES2630031T3 (es) 2010-09-28 2017-08-17 Aegerion Pharmaceuticals, Inc. Un polipéptido de leptina pinnípedo-humano quimérico con solubilidad aumentada
CN104829707B (zh) * 2015-05-06 2017-12-19 广东省生物资源应用研究所 一条cd环和e螺旋区突变的瘦素活性肽及其编码基因和应用
CN110183530A (zh) 2019-06-21 2019-08-30 深圳市亚辉龙生物科技股份有限公司 瘦素免疫原、杂交瘤细胞、单克隆抗体、多克隆抗体及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
CA2211656A1 (en) * 1995-01-31 1996-08-08 Margret B. Basinski Anti-obesity proteins
AU4766596A (en) * 1995-01-31 1996-08-21 Eli Lilly And Company Ob gene product antibodies
US5552523A (en) * 1995-01-31 1996-09-03 Eli Lilly And Company Anti-obesity proteins
WO1996031526A1 (en) * 1995-04-06 1996-10-10 Amylin Pharmaceuticals, Inc. Anti-obesity agents
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
NO985683L (no) 1998-12-04
AR008765A1 (es) 2000-02-23
CA2257240A1 (en) 1997-12-11
TR199802534T2 (xx) 1999-03-22
CN1221426A (zh) 1999-06-30
BR9709529A (pt) 1999-08-10
PL330361A1 (en) 1999-05-10
IL127153A0 (en) 1999-09-22
NZ332879A (en) 2000-09-29
JP2000512137A (ja) 2000-09-19
AU3337297A (en) 1998-01-05
CZ397898A3 (cs) 1999-04-14
WO1997046585A3 (en) 1998-04-23
EP0912609A2 (en) 1999-05-06
WO1997046585A2 (en) 1997-12-11
KR20000016402A (ko) 2000-03-25

Similar Documents

Publication Publication Date Title
NO985683D0 (no) Fragmenter av leptin (ob protein)
DE69732808D1 (de) Schleifvorrichtung
NO985680L (no) Peptidderivater
NO20004522D0 (no) Kitinase-kitinbindende fragmenter
ATE196152T1 (de) Peptidderivate
AU3451397A (en) Modified protein g and fragments thereof
FI961584A7 (fi) C-reaktiivisista proteiinifragmenteista johdetut oligopeptidit
DE59708449D1 (de) Substituierte p-trifluormethylphenyluracile
TR199701666A3 (tr) Sismanliga karsi proteinler
DE59707428D1 (de) Substituierte 1-methyl-3-benzyluracile
DE59602924D1 (de) Knochenraspel
DE59712222D1 (de) Substituierte phenyluracile
KR970056943U (ko) 약제 분쇄기
BR7601137U (pt) Bone
HK1019756A (en) Fragments of leptin (ob protein)
AU2003204475A1 (en) Fragments of leptin (ob protein)
KR980005237U (ko) 마그네트론
KR970059003U (ko) 조인트용 부트
NO975427D0 (no) Snöfreser
SE9602287D0 (sv) Novel protein and methods for its use
SE9601761D0 (sv) T-ventilförfarande
KR970053645U (ko) 파쇄기의 구동장치
ID16704A (id) Metoda penyembuhan
KR970060479U (ko) 자료보관대
KR980006021U (ko) 마그네트론

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application