NO985972L - Indolinderivater anvendelige som 5-HT-2C reseptorantagonister - Google Patents

Indolinderivater anvendelige som 5-HT-2C reseptorantagonister

Info

Publication number
NO985972L
NO985972L NO985972A NO985972A NO985972L NO 985972 L NO985972 L NO 985972L NO 985972 A NO985972 A NO 985972A NO 985972 A NO985972 A NO 985972A NO 985972 L NO985972 L NO 985972L
Authority
NO
Norway
Prior art keywords
receptor antagonists
derivatives useful
indoline derivatives
indoline
useful
Prior art date
Application number
NO985972A
Other languages
English (en)
Norwegian (no)
Other versions
NO985972D0 (no
Inventor
Steven Mark Bromidge
Ian Thomson Forbes
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO985972D0 publication Critical patent/NO985972D0/no
Publication of NO985972L publication Critical patent/NO985972L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO985972A 1996-06-20 1998-12-18 Indolinderivater anvendelige som 5-HT-2C reseptorantagonister NO985972L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9612883.0A GB9612883D0 (en) 1996-06-20 1996-06-20 Novel compounds
PCT/EP1997/003156 WO1997048699A1 (en) 1996-06-20 1997-06-16 Indoline derivatives useful as 5-ht-2c receptor antagonists

Publications (2)

Publication Number Publication Date
NO985972D0 NO985972D0 (no) 1998-12-18
NO985972L true NO985972L (no) 1998-12-18

Family

ID=10795575

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985972A NO985972L (no) 1996-06-20 1998-12-18 Indolinderivater anvendelige som 5-HT-2C reseptorantagonister

Country Status (33)

Country Link
US (1) US6369060B1 (de)
EP (1) EP0912554B1 (de)
JP (1) JP2000512306A (de)
KR (1) KR20000022045A (de)
CN (1) CN1229408A (de)
AP (2) AP9801410A0 (de)
AR (1) AR008243A1 (de)
AT (1) ATE228514T1 (de)
AU (1) AU718597B2 (de)
BG (1) BG103089A (de)
BR (1) BR9709911A (de)
CA (1) CA2258240A1 (de)
CO (1) CO4890847A1 (de)
CZ (1) CZ420598A3 (de)
DE (1) DE69717449T2 (de)
DZ (1) DZ2250A1 (de)
EA (1) EA001780B1 (de)
ES (1) ES2187783T3 (de)
GB (1) GB9612883D0 (de)
HU (1) HUP9903439A3 (de)
ID (1) ID19433A (de)
IL (1) IL127417A0 (de)
MA (1) MA24214A1 (de)
NO (1) NO985972L (de)
NZ (1) NZ333229A (de)
OA (1) OA10944A (de)
PE (1) PE86698A1 (de)
PL (1) PL330796A1 (de)
SK (1) SK282706B6 (de)
TR (1) TR199802661T2 (de)
TW (1) TW382015B (de)
WO (1) WO1997048699A1 (de)
ZA (1) ZA975415B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999043650A2 (en) * 1998-02-25 1999-09-02 Smithkline Beecham Plc Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives
GB0019950D0 (en) * 2000-08-12 2000-09-27 Smithkline Beecham Plc Compounds
JP2005535560A (ja) * 2001-11-28 2005-11-24 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 治療用の化合物
AU2003217817A1 (en) * 2002-03-04 2003-09-22 Pharmacia And Upjohn Company Pyridinyloxy derivatives as 5-ht receptor ligands
KR101062376B1 (ko) * 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
US8940732B2 (en) 2009-01-16 2015-01-27 Massachusetts Institute Of Technology Diagnosis of autism spectrum disorders and its treatment with an antagonist or inhibitor of the 5-HT2c receptor signaling pathway
EP2651403B1 (de) 2010-12-17 2020-12-02 Glaxo Group Limited Verwendung von lp-pla2-inhibitoren zur behandlung und vorbeugung von augenerkrankungen
WO2014046544A1 (en) 2012-09-21 2014-03-27 Aapa B.V. Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989001333A1 (en) 1987-08-07 1989-02-23 The Australian National University IMIDAZO[1,2-b]PYRIDAZINES
NZ254785A (en) * 1992-08-20 1995-09-26 Smithkline Beecham Plc Heterocyclically-condensed indoles and medicaments
GB9313913D0 (en) 1993-07-06 1993-08-18 Smithkline Beecham Plc Novel compounds
AU699727B2 (en) * 1995-02-02 1998-12-10 Smithkline Beecham Plc Indole derivatives as 5-HT receptor antagonist
GB9607219D0 (en) * 1996-04-04 1996-06-12 Smithkline Beecham Plc Novel compounds
GB9615767D0 (en) * 1996-07-26 1996-09-04 Smithkline Beecham Plc Novel treatment

Also Published As

Publication number Publication date
HUP9903439A2 (en) 2000-07-28
CA2258240A1 (en) 1997-12-24
EP0912554B1 (de) 2002-11-27
SK175298A3 (en) 1999-05-07
BR9709911A (pt) 1999-08-10
PL330796A1 (en) 1999-06-07
CN1229408A (zh) 1999-09-22
AP9701037A0 (en) 1997-07-31
AP745A (en) 1999-04-28
GB9612883D0 (en) 1996-08-21
JP2000512306A (ja) 2000-09-19
EA199900043A1 (ru) 1999-06-24
CO4890847A1 (es) 2000-02-28
NO985972D0 (no) 1998-12-18
NZ333229A (de) 2000-01-28
AU3260297A (en) 1998-01-07
ID19433A (id) 1998-07-09
SK282706B6 (sk) 2002-11-06
TR199802661T2 (xx) 1999-03-22
ZA975415B (en) 1998-12-21
AU718597B2 (en) 2000-04-20
CZ420598A3 (cs) 1999-06-16
ATE228514T1 (de) 2002-12-15
US6369060B1 (en) 2002-04-09
BG103089A (en) 1999-09-30
MA24214A1 (fr) 1997-12-31
EP0912554A1 (de) 1999-05-06
HUP9903439A3 (en) 2002-12-28
AP9801410A0 (en) 1998-12-31
DE69717449T2 (de) 2003-10-02
AR008243A1 (es) 1999-12-29
ES2187783T3 (es) 2003-06-16
DE69717449D1 (de) 2003-01-09
EA001780B1 (ru) 2001-08-27
WO1997048699A1 (en) 1997-12-24
OA10944A (en) 2003-02-27
IL127417A0 (en) 1999-10-28
PE86698A1 (es) 1999-01-28
TW382015B (en) 2000-02-11
KR20000022045A (ko) 2000-04-25
DZ2250A1 (fr) 2002-12-18

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