NO986035L - Kombinasjoner omfattende VX478, zidovudin og/eller 1592U89 for anvendelse i behandling av HIV - Google Patents

Kombinasjoner omfattende VX478, zidovudin og/eller 1592U89 for anvendelse i behandling av HIV

Info

Publication number: NO986035L
Authority: NO; Norway
Prior art keywords: hiv; combinations; zidovudine; treatment; amino
Prior art date: 1996-06-25

Application number

NO986035A

Other languages

English (en)

Norwegian (no)

Other versions

NO986035D0 (no

Inventor

Martha Heiden St Clair

David Walter Barry

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-25

Filing date

1998-12-22

Publication date

1999-02-23

1996-07-04 Priority claimed from GBGB9614024.9A external-priority patent/GB9614024D0/en

1998-12-22 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1998-12-22 Publication of NO986035D0 publication Critical patent/NO986035D0/no

1999-02-23 Publication of NO986035L publication Critical patent/NO986035L/no

Links

HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title abstract 3
229960002555 zidovudine Drugs 0.000 title abstract 2
239000002777 nucleoside Substances 0.000 abstract 2
150000003833 nucleoside derivatives Chemical class 0.000 abstract 2
208000031886 HIV Infections Diseases 0.000 abstract 1
230000036436 anti-hiv Effects 0.000 abstract 1
KXDHJXZQYSOELW-UHFFFAOYSA-N carbonic acid monoamide Natural products NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
239000000969 carrier Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
-1 tetrahydro-3-furanyl ester Chemical class 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical compound C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Virology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

NO986035A 1996-06-25 1998-12-22 Kombinasjoner omfattende VX478, zidovudin og/eller 1592U89 for anvendelse i behandling av HIV NO986035L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US2217896P	1996-06-25	1996-06-25
GBGB9614024.9A GB9614024D0 (en)	1996-07-04	1996-07-04	Antiviral therapeutic combinations
PCT/EP1997/003246 WO1997049410A1 (en)	1996-06-25	1997-06-23	Combinations comprising vx478, zidovudine and/or 1592u89 for use in the treatment of hiv

Publications (2)

Publication Number	Publication Date
NO986035D0 NO986035D0 (no)	1998-12-22
NO986035L true NO986035L (no)	1999-02-23

Family

ID=26309631

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO986035A NO986035L (no)	1996-06-25	1998-12-22	Kombinasjoner omfattende VX478, zidovudin og/eller 1592U89 for anvendelse i behandling av HIV

Country Status (26)

Country	Link
US (1)	US6486136B1 (is)
EP (1)	EP0910386B1 (is)
KR (1)	KR20000022225A (is)
CN (1)	CN1306430A (is)
AP (1)	AP9801418A0 (is)
AT (1)	ATE230267T1 (is)
AU (1)	AU723877C (is)
BR (1)	BR9709951A (is)
CA (1)	CA2262765A1 (is)
CO (1)	CO4910137A1 (is)
CZ (1)	CZ429398A3 (is)
DE (1)	DE69718168T2 (is)
EA (1)	EA001457B1 (is)
ES (1)	ES2189964T3 (is)
HU (1)	HUP9903098A3 (is)
ID (1)	ID18739A (is)
IL (1)	IL127350A0 (is)
IS (1)	IS4913A (is)
NO (1)	NO986035L (is)
NZ (1)	NZ333098A (is)
PE (1)	PE87398A1 (is)
PL (1)	PL330791A1 (is)
TR (1)	TR199802703T2 (is)
WO (1)	WO1997049410A1 (is)
YU (1)	YU58498A (is)
ZA (1)	ZA975565B (is)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY115461A (en)	1995-03-30	2003-06-30	Wellcome Found	Synergistic combinations of zidovudine, 1592u89 and 3tc
WO1998052571A1 (en) *	1997-05-17	1998-11-26	Glaxo Group Limited	Antiviral combinations containing the carbocyclic nucleoside 1592u89
GB9709945D0 (en)	1997-05-17	1997-07-09	Glaxo Group Ltd	A novel salt
GB9802472D0 (en) *	1998-02-06	1998-04-01	Glaxo Group Ltd	Pharmaceutical compositions
US6194391B1 (en) *	1998-06-24	2001-02-27	Emory University	3′-azido-2′,3′-dideoxyuridine administration to treat HIV and related test protocol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4724232A (en)	1985-03-16	1988-02-09	Burroughs Wellcome Co.	Treatment of human viral infections
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.
GB9104740D0 (en) *	1991-03-06	1991-04-17	Wellcome Found	Antiviral nucleoside combination
GB9307013D0 (en) *	1993-04-02	1993-05-26	Wellcome Found	Therapeutic combinations
IS2334B (is) *	1992-09-08	2008-02-15	Vertex Pharmaceuticals Inc., (A Massachusetts Corporation)	Aspartyl próteasi hemjari af nýjum flokki súlfonamíða
US5723490A (en) *	1992-09-08	1998-03-03	Vertex Pharmaceuticals Incorporated	THF-containing sulfonamide inhibitors of aspartyl protease
UA49803C2 (uk)	1994-06-03	2002-10-15	Дж.Д. Сьорль Енд Ко	Спосіб лікування ретровірусних інфекцій
US5646180A (en) *	1995-12-05	1997-07-08	Vertex Pharmaceuticals Incorporated	Treatment of the CNS effects of HIV

1997
- 1997-06-23 CA CA002262765A patent/CA2262765A1/en not_active Abandoned
- 1997-06-23 CZ CZ984293A patent/CZ429398A3/cs unknown
- 1997-06-23 ES ES97928262T patent/ES2189964T3/es not_active Expired - Lifetime
- 1997-06-23 CN CN97197356A patent/CN1306430A/zh active Pending
- 1997-06-23 AU AU32626/97A patent/AU723877C/en not_active Ceased
- 1997-06-23 EA EA199801046A patent/EA001457B1/ru not_active IP Right Cessation
- 1997-06-23 PL PL97330791A patent/PL330791A1/xx unknown
- 1997-06-23 IL IL12735097A patent/IL127350A0/xx unknown
- 1997-06-23 PE PE1997000535A patent/PE87398A1/es not_active Application Discontinuation
- 1997-06-23 WO PCT/EP1997/003246 patent/WO1997049410A1/en not_active Ceased
- 1997-06-23 KR KR1019980710645A patent/KR20000022225A/ko not_active Withdrawn
- 1997-06-23 EP EP97928262A patent/EP0910386B1/en not_active Expired - Lifetime
- 1997-06-23 AT AT97928262T patent/ATE230267T1/de not_active IP Right Cessation
- 1997-06-23 DE DE69718168T patent/DE69718168T2/de not_active Expired - Fee Related
- 1997-06-23 HU HU9903098A patent/HUP9903098A3/hu unknown
- 1997-06-23 ZA ZA975565A patent/ZA975565B/xx unknown
- 1997-06-23 AP APAP/P/1998/001418A patent/AP9801418A0/en unknown
- 1997-06-23 BR BR9709951A patent/BR9709951A/pt not_active IP Right Cessation
- 1997-06-23 CO CO97034780A patent/CO4910137A1/es unknown
- 1997-06-23 TR TR1998/02703T patent/TR199802703T2/xx unknown
- 1997-06-23 US US09/202,674 patent/US6486136B1/en not_active Expired - Fee Related
- 1997-06-23 ID IDP972146A patent/ID18739A/id unknown
1998
- 1998-11-30 IS IS4913A patent/IS4913A/is unknown
- 1998-12-16 YU YU58498A patent/YU58498A/sr unknown
- 1998-12-18 NZ NZ333098A patent/NZ333098A/en unknown
- 1998-12-22 NO NO986035A patent/NO986035L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NZ333098A (en)	2000-08-25
KR20000022225A (ko)	2000-04-25
HU9903098D0 (en)	1999-10-28
HUP9903098A2 (hu)	1999-12-28
DE69718168D1 (de)	2003-02-06
AU723877C (en)	2001-08-23
ES2189964T3 (es)	2003-07-16
EA001457B1 (ru)	2001-04-23
ATE230267T1 (de)	2003-01-15
DE69718168T2 (de)	2003-10-23
WO1997049410A1 (en)	1997-12-31
EA199801046A1 (ru)	1999-08-26
EP0910386A1 (en)	1999-04-28
EP0910386B1 (en)	2003-01-02
CZ429398A3 (cs)	1999-05-12
IS4913A (is)	1998-11-30
HUP9903098A3 (en)	2000-01-28
ID18739A (id)	1998-05-07
AU3262697A (en)	1998-01-14
PL330791A1 (en)	1999-06-07
ZA975565B (en)	1998-12-23
BR9709951A (pt)	1999-08-10
IL127350A0 (en)	1999-10-28
TR199802703T2 (xx)	1999-03-22
AP9801418A0 (en)	1998-12-31
AU723877B2 (en)	2000-09-07
CA2262765A1 (en)	1997-12-31
US6486136B1 (en)	2002-11-26
NO986035D0 (no)	1998-12-22
CN1306430A (zh)	2001-08-01
PE87398A1 (es)	1999-01-15
CO4910137A1 (es)	2000-04-24
YU58498A (en)	1999-11-22

Legal Events

Date	Code	Title	Description
2002-03-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
MY115461A (en)	2003-06-30	Synergistic combinations of zidovudine, 1592u89 and 3tc
CN100471502C (zh)	2009-03-25	细胞增殖用组合物
NO20053817L (no)	2005-10-13	Preparater og fremgangsmater for antiviral kombinasjonsterapi.
NO986034L (no)	1999-02-23	Kombinasjoner omfattende VX 478, ZidovudÞn, FTC og/eller 3TC for anvendelse i behandling av HIV
NO975585L (no)	1998-02-05	C-4' modifiserte adenosin-kinase inhibitorer
BR0008447A (pt)	2002-01-15	Métodos de tratamento de distúrbios mitocondriais
CA2302156A1 (en)	1999-03-11	Methods for modulating the axonal outgrowth of central nervous system neurons
ES2065914T3 (es)	1995-03-01	Nucleosidos terapeuticos.
JP2010215648A (ja)	2010-09-30	コラーゲン産生促進用組成物
BG103959A (en)	2000-12-29	Carbocyclic nucleoside hemisulphate and its application in the treatment of viral infections
AP9801418A0 (en)	1998-12-31	Combination comprising VX478, zidovudine and/or 1592U89 for use in the treatment of HIV.
Laibson et al.	1977	Double controlled comparison of IDU and trifluorothymidine in thirty-three patients with superficial herpetic keratitis
NO995620L (no)	2000-01-14	Antivirale kombinasjoner inneholdende karbocyklisk nukleosid 1592U89
AR007615A1 (es)	1999-11-10	Combinaciones antivirales, formulaciones conteniendo las mismas, uso de los mismos en la manufactura de medicamentos y un articulo que los contiene.
NO995621L (no)	2000-01-14	Antivirale kombinasjoner inneholdende karbocyklisk nukleoid 1592U89
WO2025257289A3 (en)	2026-01-22	Methods and compositions for transfecting cells
RU93004467A (ru)	1995-11-27	Замещенные пуриновые арабинозы, их применение, фармацевтическая композиция
AR007616A1 (es)	1999-11-10	Combinaciones antivirales
FR2863496A1 (fr)	2005-06-17	Composition therapeutique destinee au traitement des troubles de l'accomodation de l'oeil humain
TH34652A (th)	1999-08-27	การรวมสารต้านไวรัส
HK1093891B (en)	2010-05-28	Composition for promoting collagen production