NO986202L - FremgangsmÕte for fremstilling av rekombinant adÚnovirus - Google Patents
FremgangsmÕte for fremstilling av rekombinant adÚnovirusInfo
- Publication number
- NO986202L NO986202L NO986202A NO986202A NO986202L NO 986202 L NO986202 L NO 986202L NO 986202 A NO986202 A NO 986202A NO 986202 A NO986202 A NO 986202A NO 986202 L NO986202 L NO 986202L
- Authority
- NO
- Norway
- Prior art keywords
- adunovirus
- recombinant
- preparation
- recombinant adunovirus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/861—Adenoviral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9608164A FR2750433B1 (fr) | 1996-07-01 | 1996-07-01 | Procede de production d'adenovirus recombinants |
| US2666796P | 1996-09-25 | 1996-09-25 | |
| PCT/FR1997/001107 WO1998000524A1 (fr) | 1996-07-01 | 1997-06-20 | Procede de production d'adenovirus recombinants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO986202D0 NO986202D0 (no) | 1998-12-30 |
| NO986202L true NO986202L (no) | 1999-02-15 |
Family
ID=26232805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO986202A NO986202L (no) | 1996-07-01 | 1998-12-30 | FremgangsmÕte for fremstilling av rekombinant adÚnovirus |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6485958B2 (no) |
| EP (1) | EP0944717A1 (no) |
| JP (1) | JP2000514290A (no) |
| KR (1) | KR20050043996A (no) |
| AU (1) | AU3447097A (no) |
| BR (1) | BR9710030A (no) |
| CA (1) | CA2258158A1 (no) |
| CZ (1) | CZ438398A3 (no) |
| HU (1) | HU224558B1 (no) |
| IL (1) | IL127692A0 (no) |
| NO (1) | NO986202L (no) |
| SK (1) | SK181098A3 (no) |
| WO (1) | WO1998000524A1 (no) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU722196B2 (en) * | 1995-08-30 | 2000-07-27 | Genzyme Corporation | Chromatographic purification of adenovirus and AAV |
| CZ438398A3 (cs) * | 1996-07-01 | 1999-03-17 | Rhone-Poulenc Rorer S. A. | Způsob přípravy rekombinantních adenovirů |
| US20060275781A1 (en) * | 2004-11-03 | 2006-12-07 | Introgen Therapeutics Inc. | Novel method for the protection and purification of adenoviral vectors |
| JP4492826B2 (ja) | 1996-11-20 | 2010-06-30 | イントロジェン セラピューティクス,インコーポレイテッド | アデノウイルスベクターの産生および精製のための改良された方法 |
| US7732129B1 (en) * | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| US20080261289A1 (en) * | 1996-12-13 | 2008-10-23 | Schering-Plough Corporation | Compositions comprising viruses and methods for concentrating virus preparations |
| DE69739961D1 (de) | 1996-12-13 | 2010-09-23 | Schering Corp | Methoden zur Virus-Reinigung |
| US6544769B1 (en) * | 1996-12-13 | 2003-04-08 | Schering Corporation | Compostions comprising viruses and methods for concentrating virus preparations |
| US6146891A (en) * | 1997-01-31 | 2000-11-14 | Schering Corporation | Methods for cultivating cells and propagating viruses |
| US6989264B2 (en) * | 1997-09-05 | 2006-01-24 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| EE200000605A (et) * | 1998-04-22 | 2002-04-15 | Genvec, Inc. | Adenoviiruse efektiivne puhastamine |
| EP1080218A1 (en) * | 1998-05-27 | 2001-03-07 | University of Florida | Method of preparing recombinant adeno-associated virus compositions by using an iodixanol gradient |
| AU770672B2 (en) * | 1998-05-27 | 2004-02-26 | University Of Florida | Method of preparing recombinant adeno-associated virus compositions by using an iodixananol gradient |
| US6689600B1 (en) * | 1998-11-16 | 2004-02-10 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
| FR2788064B1 (fr) * | 1998-12-31 | 2003-01-31 | Aventis Pharma Sa | Methode de separation de particules virales |
| JP2003523169A (ja) * | 1998-12-31 | 2003-08-05 | アバンテイス・フアルマ・エス・アー | ウイルス粒子の分離法 |
| DE60029195T2 (de) | 1999-02-22 | 2007-06-28 | Transgene S.A. | Verfahren zur Gewinnung von purifizierter Virenzusammensetzung |
| US6783939B2 (en) * | 2000-07-07 | 2004-08-31 | Alphavax, Inc. | Alphavirus vectors and virosomes with modified HIV genes for use in vaccines |
| CA2455499C (en) * | 2001-08-08 | 2011-06-21 | The Trustees Of The University Of Pennsylvania | Method for purification of viral vectors having proteins which bind sialic acid |
| WO2003023026A1 (en) * | 2001-09-06 | 2003-03-20 | Alphavax, Inc. | Alphavirus replicon vector systems |
| JP4550421B2 (ja) | 2001-12-12 | 2010-09-22 | メイン・ファ−マ・インタ−ナショナル・プロプライエタリ−・リミテッド | ウイルスの保存のための組成物 |
| BR0306925A (pt) * | 2002-01-18 | 2004-11-09 | Schering Ag | Formulações estabilizadas de adenovìrus |
| US20030224354A1 (en) * | 2002-05-30 | 2003-12-04 | Introgen Therapeutics Inc. | Quantifying viral particles with intrinsic fluorescence |
| EP1371723A1 (en) * | 2002-06-12 | 2003-12-17 | Procorde GmbH | Process for preparing an adenovirus-containing preparation |
| CA2496918A1 (en) * | 2002-08-28 | 2004-03-11 | Introgen Therapeutics Inc. | Chromatographic methods for adenovirus purification |
| JP4991108B2 (ja) | 2002-12-13 | 2012-08-01 | アルファバックス,インコーポレイティド | 多抗原性アルファウイルス・レプリコン粒子及び方法 |
| ES2630222T3 (es) * | 2002-12-13 | 2017-08-18 | Alphavax, Inc. | Partículas alfavíricas y métodos de preparación |
| CN1791678A (zh) * | 2003-03-20 | 2006-06-21 | 阿尔法瓦克斯公司 | 改进的甲病毒复制子和辅助构建体 |
| US20040229335A1 (en) | 2003-05-15 | 2004-11-18 | Introgen Therapeutics, Inc. | Methods and compositions for the production of adenoviral vectors |
| JP2007523621A (ja) * | 2003-06-18 | 2007-08-23 | オニックス ファーマシューティカルズ,インコーポレイティド | ウイルスを精製するための方法 |
| PT1651666E (pt) * | 2003-07-11 | 2009-08-28 | Alphavax Inc | Vacinas de citomegalovírus à base de alfavírus |
| ATE500267T1 (de) | 2003-07-21 | 2011-03-15 | Transgene Sa | Multifunktionelle cytokine |
| CN1922308A (zh) * | 2004-02-23 | 2007-02-28 | 克鲁塞尔荷兰公司 | 病毒纯化方法 |
| AU2005245956B2 (en) * | 2004-05-18 | 2011-05-19 | Alphavax, Inc. | TC-83-derived alphavirus vectors, particles and methods |
| US8900804B2 (en) * | 2004-11-22 | 2014-12-02 | Cedars-Sinai Medical Center | Methods and solutions for tissue preservation |
| DK1865940T3 (da) | 2005-03-21 | 2013-03-04 | Virobay Inc | Alfaketoamidforbindelser som cysteinproteasehæmmere |
| CA2602944C (en) * | 2005-04-11 | 2015-08-11 | Crucell Holland B.V. | Virus purification using ultrafiltration |
| US8465732B2 (en) | 2007-01-19 | 2013-06-18 | Cornell Research Foundation, Inc. | Endothelial cells expressing adenovirus E4ORF1 and methods of use thereof |
| US8420103B2 (en) | 2007-01-30 | 2013-04-16 | Transgene S.A. | Papillomavirus vaccines |
| NZ582495A (en) * | 2007-06-21 | 2012-05-25 | Alphavax Inc | Promoterless cassettes for expression of alphavirus structural proteins |
| WO2010060719A1 (en) | 2008-11-03 | 2010-06-03 | Crucell Holland B.V. | Method for the production of adenoviral vectors |
| KR20120052352A (ko) | 2009-08-07 | 2012-05-23 | 트랜스진 에스.에이. | Hbv 감염을 치료하는 조성물 |
| KR101805938B1 (ko) | 2009-10-15 | 2018-01-10 | 얀센 백신스 앤드 프리벤션 비.브이. | 고밀도 세포 배양액에서 아데노바이러스의 정제 방법 |
| CN102791852B (zh) | 2009-10-15 | 2014-05-07 | 克鲁塞尔荷兰公司 | 纯化腺病毒颗粒的方法 |
| EP2536829B1 (en) | 2010-02-15 | 2016-04-06 | Crucell Holland B.V. | Method for the production of Ad26 adenoviral vectors |
| JP2013523175A (ja) * | 2010-04-14 | 2013-06-17 | イーエムディー・ミリポア・コーポレーション | 高力価、高純度のウイルスストックの作製方法及びその使用方法 |
| BR112013014457A8 (pt) | 2010-12-09 | 2017-12-19 | Pasteur Institut | usos da enzima 6-metilguanina-dna-metiltrasferase (mgmt, ec 2.1.1.63) para aumentar a produção de proteína heteróloga, bem como vetor de expressão, células recombinantes e polipeptídeo de fusão compreendendo sinal de secreção peptídica e proteína snap |
| TWI575070B (zh) | 2011-07-12 | 2017-03-21 | 傳斯堅公司 | Hbv聚合酶突變體 |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
| TW201321016A (zh) | 2011-09-29 | 2013-06-01 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二) |
| CA2864956C (en) | 2012-03-12 | 2021-11-09 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| US9119813B2 (en) | 2012-03-22 | 2015-09-01 | Crucell Holland B.V. | Vaccine against RSV |
| AP2014007993A0 (en) | 2012-03-22 | 2014-10-31 | Crucell Holland Bv | Vaccine against RSV |
| SG11201408101TA (en) | 2012-06-05 | 2015-01-29 | Univ Australian | Vaccination with interleukin-4 antagonists |
| WO2014066443A1 (en) | 2012-10-23 | 2014-05-01 | Emory University | Gm-csf and il-4 conjugates, compositions, and methods related thereto |
| CN105189739A (zh) * | 2013-02-28 | 2015-12-23 | 普赛奥克苏斯治疗公司 | 生产腺病毒的方法 |
| KR102089121B1 (ko) | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
| CN110590916A (zh) | 2013-04-25 | 2019-12-20 | 扬森疫苗与预防公司 | 稳定化的可溶性融合前rsv f多肽 |
| KR102313153B1 (ko) | 2013-06-17 | 2021-10-15 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 가용성 예비융합 rsv f 폴리펩타이드 |
| GB201415579D0 (en) * | 2014-09-03 | 2014-10-15 | Psioxus Therapeutics Ltd | A process |
| RU2745300C2 (ru) * | 2014-06-27 | 2021-03-23 | Анджиокрин Биосайенс, Инк. | Клетки нервной системы, экспрессирующие e4orf1 аденовируса, и способы их получения и применения |
| JP2017529070A (ja) * | 2014-08-27 | 2017-10-05 | サイオクサス セラピューティクス リミテッド | アデノウイルスの製造方法 |
| EP3198009B1 (en) | 2014-09-24 | 2021-09-08 | Salk Institute for Biological Studies | Oncolytic tumor viruses and methods of use |
| SG11201704919SA (en) | 2015-01-13 | 2017-07-28 | Alfa Wassermann Inc | Methods of purifying adeno-associated virus (aav) and/or recombinant adeno-associated virus (raav) |
| EP3256156B1 (en) | 2015-02-13 | 2025-02-12 | Transgene | Immunotherapeutic vaccine and antibody combination therapy |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| SI3283634T1 (sl) | 2015-04-14 | 2019-08-30 | Janssen Vaccines & Prevention B.V. | Rekombinantni adenovirus, ki izraža dva transgena z dvosmernim promotorjem |
| JP7189014B2 (ja) | 2015-07-07 | 2022-12-13 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | Rsvに対するワクチン |
| US10457708B2 (en) | 2015-07-07 | 2019-10-29 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion RSV F polypeptides |
| EP3390428B1 (en) * | 2016-02-23 | 2019-09-25 | Salk Institute for Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
| KR20220041966A (ko) | 2016-04-05 | 2022-04-01 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 용해성 융합-전 rsv f 단백질 |
| BR112018070323A2 (pt) | 2016-04-05 | 2019-01-29 | Janssen Vaccines & Prevention Bv | vacina contra rsv |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| WO2017194655A1 (en) | 2016-05-12 | 2017-11-16 | Janssen Vaccines & Prevention B.V. | Potent and balanced bidirectional promoter |
| IL264119B2 (en) | 2016-05-30 | 2023-04-01 | Janssen Vaccines Prevention B V | f proteins of rsv are stabilized before fusion |
| EP3472327B1 (en) | 2016-06-20 | 2020-08-19 | Janssen Vaccines & Prevention B.V. | Potent and balanced bidirectional promoter |
| EP3484506A1 (en) | 2016-07-14 | 2019-05-22 | Janssen Vaccines & Prevention B.V. | Hpv vaccines |
| EP3522920A2 (en) | 2016-10-10 | 2019-08-14 | Transgene SA | Immunotherapeutic product and mdsc modulator combination therapy |
| JP7078620B2 (ja) | 2016-11-16 | 2022-05-31 | イミュノミック セラピューティックス, インコーポレイテッド | アレルギーの治療のための核酸 |
| JP7794421B2 (ja) | 2016-12-12 | 2026-01-06 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 腫瘍を標的にする合成アデノウイルスおよびその使用 |
| CN110268061B (zh) | 2017-02-09 | 2024-07-16 | 扬森疫苗与预防公司 | 用于表达异源基因的有效的短启动子 |
| EP4512477A3 (en) | 2017-04-22 | 2025-06-11 | Immunomic Therapeutics, Inc. | Improved lamp constructs |
| CN110913892A (zh) | 2017-05-02 | 2020-03-24 | 免疫治疗有限公司 | 包含癌抗原的lamp(溶酶体相关膜蛋白)构建物 |
| AU2018267971A1 (en) | 2017-05-17 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
| SG11202001458SA (en) | 2017-09-15 | 2020-03-30 | Janssen Vaccines & Prevention Bv | Method for the safe induction of immunity against rsv |
| BR112020019942A2 (pt) | 2018-04-09 | 2021-01-26 | Salk Institute For Biological Studies | composições de adenovírus oncolítico com propriedades de replicação aprimoradas |
| CA3100004A1 (en) | 2018-05-15 | 2019-11-21 | Immunomic Therapeutics, Inc. | Improved lamp constructs comprising allergens |
| CA3113648A1 (en) | 2018-09-21 | 2020-03-26 | University Of Connecticut | Compositions and methods to restore paternal ube3a gene expression in human angelman syndrome |
| JOP20210106A1 (ar) | 2018-11-13 | 2023-01-30 | Janssen Vaccines And Prevention B V | بروتينات rsv f سابقة الاندماج مستقرة |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| EP3927833A4 (en) | 2019-02-21 | 2022-11-30 | Unleash Immuno Oncolytics, Inc. | ONCOLYTIC ADENOVIRAL VECTOR AND METHODS OF USE |
| WO2021077051A1 (en) | 2019-10-18 | 2021-04-22 | Immunomic Therapeutics, Inc | Improved lamp constructs comprising cancer antigens |
| AU2020385683A1 (en) | 2019-11-18 | 2022-06-30 | Janssen Biotech, Inc. | Vaccines based on mutant CALR and JAK2 and their uses |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| JP2023521194A (ja) | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク,インコーポレーテツド | Psma及びsteap1ワクチン並びにそれらの使用 |
| WO2022009051A1 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | A method for determining responsiveness to prostate cancer treatment |
| US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| EP4508071A1 (en) | 2022-04-10 | 2025-02-19 | Immunomic Therapeutics, Inc. | Bicistronic lamp constructs comprising immune response enhancing genes and methods of use thereof |
| WO2025158316A1 (en) | 2024-01-26 | 2025-07-31 | Janssen Biotech, Inc. | Ovarian neoantigens and use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173418A (en) * | 1985-05-10 | 1992-12-22 | Benzon Pharma, A/S | Production in Escherichia coli of extracellular Serratia spp. hydrolases |
| FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
| JPH09508017A (ja) | 1994-01-12 | 1997-08-19 | ジェネティック セラピー,インコーポレイテッド | レトロウイルスベクターの精製 |
| FR2716893B1 (fr) * | 1994-03-03 | 1996-04-12 | Rhone Poulenc Rorer Sa | Virus recombinants, leur préparation et leur utilisation thérapeutique. |
| PT751988E (pt) * | 1994-03-22 | 2000-05-31 | Immune Response Corp Inc | Producao e isolamento altamente eficientes de particulas virais |
| US5837520A (en) * | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| CZ438398A3 (cs) * | 1996-07-01 | 1999-03-17 | Rhone-Poulenc Rorer S. A. | Způsob přípravy rekombinantních adenovirů |
| JP4492826B2 (ja) | 1996-11-20 | 2010-06-30 | イントロジェン セラピューティクス,インコーポレイテッド | アデノウイルスベクターの産生および精製のための改良された方法 |
| US6261823B1 (en) * | 1996-12-13 | 2001-07-17 | Schering Corporation | Methods for purifying viruses |
| JP2003523169A (ja) * | 1998-12-31 | 2003-08-05 | アバンテイス・フアルマ・エス・アー | ウイルス粒子の分離法 |
-
1997
- 1997-06-20 CZ CZ984383A patent/CZ438398A3/cs unknown
- 1997-06-20 HU HU0001271A patent/HU224558B1/hu not_active IP Right Cessation
- 1997-06-20 BR BR9710030A patent/BR9710030A/pt not_active Application Discontinuation
- 1997-06-20 EP EP97930560A patent/EP0944717A1/fr not_active Ceased
- 1997-06-20 US US09/202,545 patent/US6485958B2/en not_active Expired - Fee Related
- 1997-06-20 IL IL12769297A patent/IL127692A0/xx unknown
- 1997-06-20 AU AU34470/97A patent/AU3447097A/en not_active Abandoned
- 1997-06-20 KR KR1020057007148A patent/KR20050043996A/ko not_active Abandoned
- 1997-06-20 JP JP10503872A patent/JP2000514290A/ja not_active Ceased
- 1997-06-20 WO PCT/FR1997/001107 patent/WO1998000524A1/fr not_active Ceased
- 1997-06-20 CA CA002258158A patent/CA2258158A1/fr not_active Abandoned
- 1997-06-20 SK SK1810-98A patent/SK181098A3/sk unknown
-
1998
- 1998-12-30 NO NO986202A patent/NO986202L/no not_active Application Discontinuation
-
2002
- 2002-10-10 US US10/267,865 patent/US6905862B2/en not_active Expired - Fee Related
-
2005
- 2005-03-23 US US11/086,678 patent/US20050287657A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0001271A3 (en) | 2002-01-28 |
| KR20050043996A (ko) | 2005-05-11 |
| US20020028497A1 (en) | 2002-03-07 |
| US6905862B2 (en) | 2005-06-14 |
| HUP0001271A1 (hu) | 2000-08-28 |
| IL127692A0 (en) | 1999-10-28 |
| US6485958B2 (en) | 2002-11-26 |
| BR9710030A (pt) | 1999-08-10 |
| CA2258158A1 (fr) | 1998-01-08 |
| SK181098A3 (en) | 1999-07-12 |
| EP0944717A1 (fr) | 1999-09-29 |
| JP2000514290A (ja) | 2000-10-31 |
| WO1998000524A1 (fr) | 1998-01-08 |
| US20050287657A1 (en) | 2005-12-29 |
| US20030143730A1 (en) | 2003-07-31 |
| CZ438398A3 (cs) | 1999-03-17 |
| NO986202D0 (no) | 1998-12-30 |
| AU3447097A (en) | 1998-01-21 |
| HU224558B1 (hu) | 2005-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO986202D0 (no) | FremgangsmÕte for fremstilling av rekombinant adÚnovirus | |
| NO307961B1 (no) | FremgangsmÕte for fremstilling av en ester | |
| NO990059D0 (no) | Analoger av kationiske proteiner | |
| NO993068L (no) | Ny forbindelsesform | |
| HUP9904239A3 (en) | High level expression of proteins | |
| NO994757L (no) | Fremgangsmåte for oral administrasjon av proteiner | |
| FI965268A0 (fi) | Menetelmä moniarvoisten alkoholien valmistamiseksi | |
| DK0806474T3 (da) | Fremgangsmåde til at stabilisere drikkevarer | |
| NO986177D0 (no) | FremgangsmÕte for fremstilling av terapeutisk DNA | |
| NO983913D0 (no) | Fremgangsmåte for oppfanging av tioler | |
| EE04154B1 (et) | Omeprasooli valmistamise meetod | |
| ID16451A (id) | Metode pembuatan filamen-filamen liosel | |
| DK0874822T3 (da) | Ny fremgangsmåde til fremstilling | |
| ID21146A (id) | Metode pengisian campuran bahan pendingin | |
| ID16838A (id) | Komposisi dekafluoropentana | |
| HUP9903744A3 (en) | Method of omeprazole preparation | |
| ID17419A (id) | Komposisi dekafluoropentana | |
| ID19540A (id) | Metode pembuatan turunan-turunan benzofenon | |
| NO992531D0 (no) | FremgangsmÕter ved fremstilling av rekombinant protein | |
| ID20291A (id) | Asam-asam oksobutirat tersubstitusi sebagai penghamba-penghambat matriks metaloproteasa | |
| NO991148D0 (no) | Fremstilling av 1-butyl-4-piperidinyl-metylamin | |
| EE9900404A (et) | Arüülaminotriasolopüridiinide valmistamise meetod | |
| ID19111A (id) | Metoda pembuatan bahan-bahan poliolefin untuk pelapisan | |
| FI951285A7 (fi) | Pilokarpiinin valmistusmenetelmä | |
| UA25135A (uk) | Спосіб гастроєюhопластики |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |