NO990485L - Biaromatiske forbindelser og farmas°ytiske og kosmetiske sammensetninger omfattende dem - Google Patents

Biaromatiske forbindelser og farmas°ytiske og kosmetiske sammensetninger omfattende dem

Info

Publication number: NO990485L
Authority: NO; Norway
Prior art keywords: alkyl; radical; cor; formula; aryl
Prior art date: 1997-06-13

Application number

NO990485A

Other languages

English (en)

Norwegian (no)

Other versions

NO990485D0 (no

Inventor

Jean Michel Bernardon

Simon Trouille

Original Assignee

Galderma Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-13

Filing date

1999-02-02

Publication date

1999-04-13

1999-02-02 Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev

1999-02-02 Publication of NO990485D0 publication Critical patent/NO990485D0/no

1999-04-13 Publication of NO990485L publication Critical patent/NO990485L/no

Links

150000001875 compounds Chemical class 0.000 title abstract 2
239000002537 cosmetic Substances 0.000 title 1
239000000203 mixture Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 10
239000004721 Polyphenylene oxide Substances 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229920000570 polyether Polymers 0.000 abstract 2
150000003254 radicals Chemical class 0.000 abstract 2
125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
150000005840 aryl radicals Chemical class 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000003712 glycosamine group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
-1 oxo radical Chemical class 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
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- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/16—Emollients or protectives, e.g. against radiation
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Birds (AREA)
Dermatology (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Toxicology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)

NO990485A 1997-06-13 1999-02-02 Biaromatiske forbindelser og farmas°ytiske og kosmetiske sammensetninger omfattende dem NO990485L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9707358A FR2764604B1 (fr)	1997-06-13	1997-06-13	Composes bi-aromatiques relies par un radical propynylene ou allenylene et compositions pharmaceutiques et cosmetiques les contenant
PCT/FR1998/001238 WO1998056783A1 (fr)	1997-06-13	1998-06-12	Composes bi-aromatiques et compositions pharmaceutiques et cosmetiques les contenant

Publications (2)

Publication Number	Publication Date
NO990485D0 NO990485D0 (no)	1999-02-02
NO990485L true NO990485L (no)	1999-04-13

Family

ID=9507951

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO990485A NO990485L (no)	1997-06-13	1999-02-02	Biaromatiske forbindelser og farmas°ytiske og kosmetiske sammensetninger omfattende dem

Country Status (26)

Country	Link
US (3)	US6103762A (cs)
EP (1)	EP0977749B1 (cs)
JP (1)	JP3665079B2 (cs)
KR (1)	KR100443179B1 (cs)
CN (1)	CN1310900C (cs)
AT (1)	ATE214385T1 (cs)
AU (1)	AU738779B2 (cs)
BG (1)	BG63501B1 (cs)
BR (1)	BR9805997A (cs)
CA (1)	CA2263362C (cs)
CZ (1)	CZ45599A3 (cs)
DE (1)	DE69804205T2 (cs)
DK (1)	DK0977749T3 (cs)
ES (1)	ES2173594T3 (cs)
FR (1)	FR2764604B1 (cs)
HU (1)	HUP0001858A3 (cs)
IL (1)	IL128336A0 (cs)
MX (1)	MXPA99001455A (cs)
NO (1)	NO990485L (cs)
NZ (1)	NZ334033A (cs)
PL (1)	PL332041A1 (cs)
PT (1)	PT977749E (cs)
RU (1)	RU2178787C2 (cs)
TR (1)	TR199900302T1 (cs)
WO (1)	WO1998056783A1 (cs)
YU (1)	YU6699A (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2764604B1 (fr)	1997-06-13	1999-09-10	Cird Galderma	Composes bi-aromatiques relies par un radical propynylene ou allenylene et compositions pharmaceutiques et cosmetiques les contenant
US20030124174A1 (en) *	2001-10-25	2003-07-03	Endo Pharmaceuticals, Inc	Method for treating non-neuropathic pain
ATE360010T1 (de) *	2001-10-31	2007-05-15	Hoffmann La Roche	Heterocyclische retioidverbindungen
US7297712B2 (en) *	2002-03-27	2007-11-20	Council Of Scientific And Industrial Research	Cationic amphiphiles for intracellular delivery of therapeutic molecules and its composition, process and method of treatment
WO2003101928A1 (en)	2002-06-04	2003-12-11	Galderma Research & Development, S.N.C.	Novel ligands that are inhibitors of the rar receptors, process for preparing them and use thereof in human medicine and in cosmetics
FR2840300B1 (fr) *	2002-06-04	2004-07-16	Galderma Res & Dev	NOUVEAUX LIGANDS INHIBITEURS DES RECEPTEURS RARs, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
BR0309786A (pt) *	2002-06-04	2005-03-22	Galderma Res & Dev	Compostos, seu uso, composição farmacêutica, composição cosmética e uso cosmético de uma composição
FR2840299B1 (fr) *	2002-06-04	2006-05-05	Galderma Res & Dev	NOUVEAUX LIGANDS INHIBITEURS DES RECEPTEURS RARs, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
GB0302094D0 (en)	2003-01-29	2003-02-26	Pharmagene Lab Ltd	EP4 receptor antagonists
GB0324269D0 (en)	2003-10-16	2003-11-19	Pharmagene Lab Ltd	EP4 receptor antagonists
FR2910320B1 (fr)	2006-12-21	2009-02-13	Galderma Res & Dev S N C Snc	Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2910321B1 (fr)	2006-12-21	2009-07-10	Galderma Res & Dev S N C Snc	Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2931661B1 (fr)	2008-05-30	2010-07-30	Galderma Res & Dev	Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
US9044408B2 (en) *	2011-10-31	2015-06-02	Avon Products, Inc.	Cosmetic use of N-heteroarylbisamide analogs and related compounds
JP7670695B2 (ja)	2019-10-02	2025-04-30	アンスティチュナショナルドゥラサンテエドゥラルシェルシュメディカル	大動脈弁の石灰化を後退、予防、又は遅延させるためのレチノイン酸受容体（ｒａｒ）アゴニストの使用

Family Cites Families (9)

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US5264578A (en) *	1987-03-20	1993-11-23	Allergan, Inc.	Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
IT1230859B (it) *	1989-06-05	1991-11-08	Corvi Camillo Spa	2 alchinilfenoli sostituiti ad azione anti infiammatoria, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
US5073564A (en) *	1990-07-06	1991-12-17	Fmc Corporation	Ethynylbenzothiophene pesticides
CA2051501C (en) *	1990-09-20	2004-02-17	Robert J. Dinerstein	1-phenyl-3-phenyl-2-propyne-1-ones as calcium uptake inhibitors
GB9203265D0 (en)	1992-02-15	1992-04-01	Fisons Plc	Pharmaceutically active compound
FR2713635B1 (fr) *	1993-12-15	1996-01-05	Cird Galderma	Nouveaux composés propynyl bi-aromatiques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
GB9420557D0 (en) *	1994-10-12	1994-11-30	Zeneca Ltd	Aromatic compounds
FR2746098B1 (fr) *	1996-03-14	1998-04-30		Composes propynyl biaromatiques
FR2764604B1 (fr)	1997-06-13	1999-09-10	Cird Galderma	Composes bi-aromatiques relies par un radical propynylene ou allenylene et compositions pharmaceutiques et cosmetiques les contenant

1997
- 1997-06-13 FR FR9707358A patent/FR2764604B1/fr not_active Expired - Fee Related
1998
- 1998-06-12 JP JP50180399A patent/JP3665079B2/ja not_active Expired - Fee Related
- 1998-06-12 CA CA002263362A patent/CA2263362C/fr not_active Expired - Fee Related
- 1998-06-12 AT AT98930852T patent/ATE214385T1/de active
- 1998-06-12 DK DK98930852T patent/DK0977749T3/da active
- 1998-06-12 EP EP98930852A patent/EP0977749B1/fr not_active Expired - Lifetime
- 1998-06-12 CN CNB988008157A patent/CN1310900C/zh not_active Expired - Fee Related
- 1998-06-12 BR BR9805997-1A patent/BR9805997A/pt not_active Application Discontinuation
- 1998-06-12 PL PL98332041A patent/PL332041A1/xx unknown
- 1998-06-12 YU YU6699A patent/YU6699A/sh unknown
- 1998-06-12 RU RU99104819/04A patent/RU2178787C2/ru not_active IP Right Cessation
- 1998-06-12 CZ CZ99455A patent/CZ45599A3/cs unknown
- 1998-06-12 TR TR1999/00302T patent/TR199900302T1/xx unknown
- 1998-06-12 WO PCT/FR1998/001238 patent/WO1998056783A1/fr not_active Ceased
- 1998-06-12 NZ NZ334033A patent/NZ334033A/xx unknown
- 1998-06-12 AU AU81143/98A patent/AU738779B2/en not_active Ceased
- 1998-06-12 PT PT98930852T patent/PT977749E/pt unknown
- 1998-06-12 MX MXPA99001455A patent/MXPA99001455A/es not_active IP Right Cessation
- 1998-06-12 HU HU0001858A patent/HUP0001858A3/hu unknown
- 1998-06-12 IL IL12833698A patent/IL128336A0/xx unknown
- 1998-06-12 KR KR10-1999-7001246A patent/KR100443179B1/ko not_active Expired - Fee Related
- 1998-06-12 ES ES98930852T patent/ES2173594T3/es not_active Expired - Lifetime
- 1998-06-12 US US09/242,130 patent/US6103762A/en not_active Expired - Fee Related
- 1998-06-12 DE DE69804205T patent/DE69804205T2/de not_active Expired - Lifetime
1999
- 1999-02-02 NO NO990485A patent/NO990485L/no not_active Application Discontinuation
- 1999-02-05 BG BG103150A patent/BG63501B1/bg unknown
2000
- 2000-05-25 US US09/577,345 patent/US6346546B1/en not_active Expired - Fee Related
2001
- 2001-10-31 US US09/984,830 patent/US6849658B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU8114398A (en)	1998-12-30
DK0977749T3 (da)	2002-06-10
PT977749E (pt)	2002-09-30
PL332041A1 (en)	1999-08-16
ES2173594T3 (es)	2002-10-16
US6346546B1 (en)	2002-02-12
HUP0001858A3 (en)	2002-01-28
CA2263362A1 (fr)	1998-12-17
MXPA99001455A (es)	2002-07-22
ATE214385T1 (de)	2002-03-15
EP0977749B1 (fr)	2002-03-13
CN1310900C (zh)	2007-04-18
CA2263362C (fr)	2007-09-18
EP0977749A1 (fr)	2000-02-09
AU738779B2 (en)	2001-09-27
BR9805997A (pt)	2000-01-25
RU2178787C2 (ru)	2002-01-27
US6849658B2 (en)	2005-02-01
NO990485D0 (no)	1999-02-02
YU6699A (sh)	2000-03-21
JP2002515068A (ja)	2002-05-21
HUP0001858A2 (hu)	2000-10-28
FR2764604B1 (fr)	1999-09-10
BG103150A (en)	1999-11-30
BG63501B1 (bg)	2002-03-29
KR100443179B1 (ko)	2004-08-04
DE69804205D1 (de)	2002-04-18
KR20000068160A (ko)	2000-11-25
WO1998056783A1 (fr)	1998-12-17
NZ334033A (en)	2000-05-26
TR199900302T1 (xx)	2004-02-23
CZ45599A3 (cs)	1999-06-16
JP3665079B2 (ja)	2005-06-29
CN1229407A (zh)	1999-09-22
DE69804205T2 (de)	2002-10-24
FR2764604A1 (fr)	1998-12-18
US20030216586A1 (en)	2003-11-20
IL128336A0 (en)	2000-01-31
US6103762A (en)	2000-08-15

Legal Events

Date	Code	Title	Description
2004-02-02	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
DK436081A (da)	1982-04-04	Substituerede acyl-derivater af 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyrer og farmaceutisk acceptable salte deraf fremgangsmaade til deres fremstilling og deres anvendelse
NZ511739A (en)	2002-11-26	New esters derived from substituted phenyl-cyclohexyl compounds
CA2011144A1 (en)	1990-09-01	Nicotinic acid derivatives and pharmaceutical compositions comprising same
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DK484886A (da)	1987-04-12	Bicycliske naphthalenderivater, deres fremstilling og deres anvendelse til medicinske og kosmetiske formaal
CA2475432A1 (en)	2003-08-14	2,4,6-triamino-1,3,5-triazine derivative
PT977749E (pt)	2002-09-30	Compostos biaromaticos e composicoes farmaceuticas e cosmeticas compreendendo os mesmos
CA2424522A1 (en)	2003-03-31	Substituted benzene derivatives or salts thereof
ATE12492T1 (de)	1985-04-15	Aryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
CA2284795A1 (en)	1998-10-08	Novel pyrimidine derivatives and processes for the preparation thereof
DK0751944T3 (da)	2001-01-08	Thiazolidiner og oxazolidiner, der er substitueret med en pyridinring, og deres anvendelse som hypoglykæmiske midler
ES2036562T3 (es)	1993-06-01	Un procedimiento para produccion de un derivado de pirrolidinamida.
IL121305A (en)	2003-01-12	Neuraminic acid derivatives and pharmaceutical compositions containing the same
KR950700243A (ko)	1995-01-16	히드록실아민으로 부터 유도되는 n, n'-치환된 이미도카본이미드 디아미드(n,n'-substituted imidocarbonimidic diamides derived from hydroxylamines)
SE8702147D0 (sv)	1987-05-22	Nya aromatiska naftylforeningar, deras framstellning och deras anvendning inom human- och veterinermedicinen och inom kosmetiken
MEP25108A (en)	2011-12-20	Phenyl- and pyridyl-tetrahydro-pyridines having tnf inhibiting activity
ATE44741T1 (de)	1989-08-15	2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.
JPS56154475A (en)	1981-11-30	Preparation of piperazine derivative
FR2603035A1 (fr)	1988-02-26	Nouveaux derives de l'indane, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant