NO990497L - Modified oligosaccharides - Google Patents
Modified oligosaccharidesInfo
- Publication number
- NO990497L NO990497L NO990497A NO990497A NO990497L NO 990497 L NO990497 L NO 990497L NO 990497 A NO990497 A NO 990497A NO 990497 A NO990497 A NO 990497A NO 990497 L NO990497 L NO 990497L
- Authority
- NO
- Norway
- Prior art keywords
- modified oligosaccharides
- natural
- oligosaccharides
- modified
- sialyl
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title 1
- 150000002482 oligosaccharides Chemical class 0.000 title 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 abstract 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 abstract 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- XBSNXOHQOTUENA-KRAHZTDDSA-N alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@@H]([C@@H](O[C@]3(O[C@H]([C@H](NC(C)=O)[C@@H](O)C3)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O)[C@@H](CO)O2)O)[C@@H](NC(C)=O)C(O)O[C@@H]1CO XBSNXOHQOTUENA-KRAHZTDDSA-N 0.000 abstract 1
- NIGUVXFURDGQKZ-UQTBNESHSA-N alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAc Chemical class O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@@H]([C@@H](O[C@]3(O[C@H]([C@H](NC(C)=O)[C@@H](O)C3)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O)[C@@H](CO)O2)O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O NIGUVXFURDGQKZ-UQTBNESHSA-N 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 229950006780 n-acetylglucosamine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Derivater av sialyl-Lewis X og A, hvor den naturlige neuraminsyreresten og den naturlige N-acetylglukosaminmonomeren er byttet ut.Derivatives of sialyl-Lewis X and A, in which the natural neuramic acid residue and the natural N-acetylglucosamine monomer are replaced.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96810526 | 1996-08-08 | ||
| EP96810527 | 1996-08-08 | ||
| EP96810636 | 1996-09-26 | ||
| PCT/EP1997/004279 WO1998006730A1 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO990497D0 NO990497D0 (en) | 1999-02-03 |
| NO990497L true NO990497L (en) | 1999-03-24 |
Family
ID=27237868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO990497A NO990497L (en) | 1996-08-08 | 1999-02-03 | Modified oligosaccharides |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0920437A1 (en) |
| JP (1) | JP2000516224A (en) |
| KR (1) | KR20000029862A (en) |
| CN (1) | CN1227563A (en) |
| AR (1) | AR008283A1 (en) |
| AU (1) | AU720381B2 (en) |
| BR (1) | BR9711117A (en) |
| CA (1) | CA2260854A1 (en) |
| CO (1) | CO4900075A1 (en) |
| CZ (1) | CZ39099A3 (en) |
| ID (1) | ID18010A (en) |
| IL (1) | IL127908A0 (en) |
| NO (1) | NO990497L (en) |
| NZ (1) | NZ334048A (en) |
| PE (1) | PE99298A1 (en) |
| PL (1) | PL331286A1 (en) |
| SK (1) | SK15699A3 (en) |
| TR (1) | TR199900245T2 (en) |
| WO (1) | WO1998006730A1 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5888984A (en) * | 1994-05-12 | 1999-03-30 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
| US8003782B1 (en) | 1999-02-01 | 2011-08-23 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
| US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
| EP1539251A4 (en) * | 2002-07-03 | 2009-02-25 | Glycomimetics Inc | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DISEASES INVOLVING ANGIOGENESIS |
| BR0315231A (en) | 2002-10-11 | 2005-08-23 | Yamanouchi Europ Bv | P-Selectin Affinity Glucose Based Compounds |
| JP2007524658A (en) * | 2003-11-19 | 2007-08-30 | グリコミメティクス， インコーポレイテッド | Glucose mimetic antagonists for both E- and P-selectin |
| ATE383367T1 (en) | 2003-11-19 | 2008-01-15 | Glycomimetics Inc | SPECIFIC ANTAGONIST FOR BOTH E- AND P-SELECTINS |
| WO2006127906A1 (en) * | 2005-05-25 | 2006-11-30 | Glycomimetics, Inc. | Heterobifunctional compounds for selectin inhibition |
| ES2375979T3 (en) | 2005-08-09 | 2012-03-07 | Glycomimetics, Inc. | GLICOMIMETIC INHIBITORS OF PA-IL LECTIN, PA-IIL LECTIN OR BOTH LECTINES OF PSEUDOMONES. |
| DK2264043T3 (en) | 2005-09-02 | 2018-01-29 | Glycomimetics Inc | Heterobifunctional pan-selectin inhibitors |
| CA2677747A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines |
| WO2009073911A1 (en) | 2007-12-10 | 2009-06-18 | Mater Medical Research Institute | Treatment and prophylaxis |
| WO2009126556A1 (en) | 2008-04-08 | 2009-10-15 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
| US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
| US9109002B2 (en) | 2011-12-22 | 2015-08-18 | Glycomimetics, Inc. | E-selectin antagonist compounds, compositions, and methods of use |
| LT2928476T (en) | 2012-12-07 | 2018-05-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
| PL3227310T3 (en) | 2014-12-03 | 2020-02-28 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
| CA3009836A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| JP2019524791A (en) | 2016-08-08 | 2019-09-05 | グリコミメティクス， インコーポレイテッド | Combinations of T cell checkpoint inhibitors with inhibitors of E-selectin or inhibitors of CXCR4 or with heterobifunctional inhibitors of both E-selectin and CXCR4 |
| CN109890421B (en) | 2016-10-07 | 2023-10-20 | 糖模拟物有限公司 | Potent multimeric E-selectin antagonist |
| US11197877B2 (en) | 2017-03-15 | 2021-12-14 | Glycomimetics. Inc. | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists |
| US11712446B2 (en) | 2017-11-30 | 2023-08-01 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| CN108299525B (en) * | 2018-01-05 | 2021-03-26 | 佛山科学技术学院 | Synthetic method of Lewis oligosaccharide-X |
| KR20200128025A (en) | 2018-03-05 | 2020-11-11 | 글리코미메틱스, 인크. | Methods of treatment of acute myeloid leukemia and related conditions |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| CN109762032A (en) * | 2019-01-16 | 2019-05-17 | 天津科技大学 | A kind of sulfonated Lewis X trisaccharide and its synthesis method and application |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993023031A1 (en) * | 1992-05-08 | 1993-11-25 | The Biomembrane Institute | Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response |
| CA2157489A1 (en) * | 1993-03-04 | 1994-09-15 | Masaaki Numata | Lewis-associated compound, process for producing the same, and anti-inflammatory |
| WO1994026760A1 (en) * | 1993-05-14 | 1994-11-24 | Cytel Corporation | SIALYL Lex ANALOGUES AS INHIBITORS OF CELLULAR ADHESION |
| WO1996020204A1 (en) * | 1994-12-28 | 1996-07-04 | Sumitomo Pharmaceuticals Company, Limited | Lewis x derivative and process for producing the same |
-
1997
- 1997-08-06 JP JP10509358A patent/JP2000516224A/en active Pending
- 1997-08-06 BR BR9711117-1A patent/BR9711117A/en not_active Application Discontinuation
- 1997-08-06 TR TR1999/00245T patent/TR199900245T2/en unknown
- 1997-08-06 CN CN97197077A patent/CN1227563A/en active Pending
- 1997-08-06 PL PL97331286A patent/PL331286A1/en unknown
- 1997-08-06 KR KR1019997001025A patent/KR20000029862A/en not_active Withdrawn
- 1997-08-06 IL IL12790897A patent/IL127908A0/en unknown
- 1997-08-06 CZ CZ99390A patent/CZ39099A3/en unknown
- 1997-08-06 AU AU43788/97A patent/AU720381B2/en not_active Ceased
- 1997-08-06 AR ARP970103580A patent/AR008283A1/en unknown
- 1997-08-06 EP EP97941916A patent/EP0920437A1/en not_active Withdrawn
- 1997-08-06 CA CA002260854A patent/CA2260854A1/en not_active Abandoned
- 1997-08-06 SK SK156-99A patent/SK15699A3/en unknown
- 1997-08-06 WO PCT/EP1997/004279 patent/WO1998006730A1/en not_active Ceased
- 1997-08-06 NZ NZ334048A patent/NZ334048A/en unknown
- 1997-08-07 PE PE1997000688A patent/PE99298A1/en not_active Application Discontinuation
- 1997-08-08 ID IDP972766A patent/ID18010A/en unknown
- 1997-08-08 CO CO97045596A patent/CO4900075A1/en unknown
-
1999
- 1999-02-03 NO NO990497A patent/NO990497L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000029862A (en) | 2000-05-25 |
| ID18010A (en) | 1998-02-19 |
| PL331286A1 (en) | 1999-07-05 |
| SK15699A3 (en) | 1999-07-12 |
| AU4378897A (en) | 1998-03-06 |
| EP0920437A1 (en) | 1999-06-09 |
| AU720381B2 (en) | 2000-06-01 |
| AR008283A1 (en) | 1999-12-29 |
| NO990497D0 (en) | 1999-02-03 |
| JP2000516224A (en) | 2000-12-05 |
| NZ334048A (en) | 2000-05-26 |
| CN1227563A (en) | 1999-09-01 |
| BR9711117A (en) | 1999-09-08 |
| PE99298A1 (en) | 1999-01-21 |
| CO4900075A1 (en) | 2000-03-27 |
| IL127908A0 (en) | 1999-11-30 |
| CZ39099A3 (en) | 1999-05-12 |
| TR199900245T2 (en) | 1999-05-21 |
| CA2260854A1 (en) | 1998-02-19 |
| WO1998006730A1 (en) | 1998-02-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO990497L (en) | Modified oligosaccharides | |
| DK0749982T3 (en) | Antioxidant grafted polysaccharides and uses thereof | |
| DE69106714D1 (en) | Hypoglykämische hydroxyharnstoffderivate. | |
| AU5062299A (en) | Formulations of anionic polysaccharides | |
| AU660282B2 (en) | Water insoluble derivatives of hyaluronic acid | |
| TW325547B (en) | Modular bus with single or double parallel termination | |
| NZ332345A (en) | Thermostable xylanases isolated from Microtetraspora | |
| MX9709146A (en) | Novel dolastatin derivatives, their preparation and use. | |
| DE69534759D1 (en) | Polyanionic polysaccharides and hydrophobic bioabsorbable polymer-containing compositions | |
| MY120511A (en) | New pesticides | |
| AU1121700A (en) | Generating a nonlinear model and generating drive signals for simulation testingusing the same | |
| NO975557D0 (en) | Immortalization and dismortalization of cells | |
| GR890100033A (en) | Method of preparation of dideoxyhydrocarbocyclic nucleosides. | |
| NO931297L (en) | ALGINATE OLIGOSACCHARIDE AND PROCEDURE FOR PRODUCING THE SAME | |
| IT9022341A0 (en) | EXTRACTS FROM ANIMAL TISSUES, USEFUL IN THERAPY AND DIAGNOSTICS. | |
| MX9703372A (en) | Optically clear polymer compositions containing an interpenetrant. | |
| TR200001745T2 (en) | Ketone peroxide derivatives, their preparation and use | |
| BR9813465A (en) | Modified polysaccharides that exhibit altered biological recognition | |
| EP1143917A3 (en) | Anticonvulsant derivatives useful in treating post traumatic stress disorder | |
| AU2895797A (en) | Carbohydrate derivatives and their solid-phase synthesis | |
| MX9603087A (en) | Process to obtain substituted aminocarbonyltriazolinones. | |
| DK1032580T3 (en) | Process for N-desmethylation of erythromycins and derivatives thereof | |
| ECSP972214A (en) | MODIFIED OLIGOSACCHARIDS | |
| NL1002204A1 (en) | Demonstration cabinet. | |
| FR2720751B1 (en) | Polyolefinic graft copolymer. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |