PL331286A1 - Modified oligosaccharides - Google Patents
Modified oligosaccharidesInfo
- Publication number
- PL331286A1 PL331286A1 PL97331286A PL33128697A PL331286A1 PL 331286 A1 PL331286 A1 PL 331286A1 PL 97331286 A PL97331286 A PL 97331286A PL 33128697 A PL33128697 A PL 33128697A PL 331286 A1 PL331286 A1 PL 331286A1
- Authority
- PL
- Poland
- Prior art keywords
- modified oligosaccharides
- oligosaccharides
- modified
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title 1
- 150000002482 oligosaccharides Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96810527 | 1996-08-08 | ||
| EP96810526 | 1996-08-08 | ||
| EP96810636 | 1996-09-26 | ||
| PCT/EP1997/004279 WO1998006730A1 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL331286A1 true PL331286A1 (en) | 1999-07-05 |
Family
ID=27237868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL97331286A PL331286A1 (en) | 1996-08-08 | 1997-08-06 | Modified oligosaccharides |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0920437A1 (en) |
| JP (1) | JP2000516224A (en) |
| KR (1) | KR20000029862A (en) |
| CN (1) | CN1227563A (en) |
| AR (1) | AR008283A1 (en) |
| AU (1) | AU720381B2 (en) |
| BR (1) | BR9711117A (en) |
| CA (1) | CA2260854A1 (en) |
| CO (1) | CO4900075A1 (en) |
| CZ (1) | CZ39099A3 (en) |
| ID (1) | ID18010A (en) |
| IL (1) | IL127908A0 (en) |
| NO (1) | NO990497L (en) |
| NZ (1) | NZ334048A (en) |
| PE (1) | PE99298A1 (en) |
| PL (1) | PL331286A1 (en) |
| SK (1) | SK15699A3 (en) |
| TR (1) | TR199900245T2 (en) |
| WO (1) | WO1998006730A1 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5888984A (en) * | 1994-05-12 | 1999-03-30 | Dermal Research Laboratories, Inc. | Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
| AU2745700A (en) | 1999-02-01 | 2000-08-18 | Dermal Research Laboratories, Inc. | A pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same |
| US7879824B2 (en) | 2001-07-31 | 2011-02-01 | Dermal Research Laboratories, Inc. | Methods of preventing or treating diseases and conditions using complex carbohydrates |
| JP2006502986A (en) * | 2002-07-03 | 2006-01-26 | グリコミメティクス， インコーポレイテッド | Compositions and methods for diagnosis and treatment of medical conditions involved in angiogenesis |
| EP1549658B1 (en) | 2002-10-11 | 2009-09-30 | Astellas Pharma Europe B.V. | Glucose-based compounds with affinity to p-selectin |
| EP1685145A2 (en) * | 2003-11-19 | 2006-08-02 | GlycoMimetics, Inc. | Glycomimetic antagonists for both e- and p-selectins |
| US7361644B2 (en) | 2003-11-19 | 2008-04-22 | Glycomimetics, Inc. | Specific antagonist for both E- and P-selectins |
| WO2006127906A1 (en) * | 2005-05-25 | 2006-11-30 | Glycomimetics, Inc. | Heterobifunctional compounds for selectin inhibition |
| JP5175190B2 (en) | 2005-08-09 | 2013-04-03 | グリコミメティクス， インコーポレイテッド | Pseudomonas-derived PA-IL lectin, PA-IIL lectin or a glycomimetic inhibitor of both lectins |
| US7728117B2 (en) | 2005-09-02 | 2010-06-01 | Glycomimetics, Inc. | Heterobifunctional pan-selectin inhibitors |
| EP2457573A1 (en) * | 2007-02-09 | 2012-05-30 | GlycoMimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and N-Acetyl hexosamines |
| US9486497B2 (en) | 2007-12-10 | 2016-11-08 | The University Of Queensland | Treatment of immunocompromised conditions |
| WO2009126556A1 (en) | 2008-04-08 | 2009-10-15 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
| US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
| SI2794626T1 (en) | 2011-12-22 | 2018-02-28 | Glycomimetics, Inc. | E-selectin antagonist compounds |
| LT2928476T (en) | 2012-12-07 | 2018-05-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
| HUE045542T2 (en) | 2014-12-03 | 2019-12-30 | Glycomimetics Inc | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
| WO2017127422A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
| CA3037850A1 (en) | 2016-10-07 | 2018-04-12 | Glycomimetics, Inc. | Highly potent multimeric e-selectin antagonists |
| CA3054605A1 (en) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
| EP3717013A1 (en) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| CN108299525B (en) * | 2018-01-05 | 2021-03-26 | 佛山科学技术学院 | Synthetic method of Lewis oligosaccharide-X |
| US11707474B2 (en) | 2018-03-05 | 2023-07-25 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| CN109762032A (en) * | 2019-01-16 | 2019-05-17 | 天津科技大学 | A kind of sulfonated Lewis X trisaccharide and its synthesis method and application |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993023031A1 (en) * | 1992-05-08 | 1993-11-25 | The Biomembrane Institute | Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response |
| US5763413A (en) * | 1993-03-04 | 1998-06-09 | Mect Corporation | Lewis-associated compound, process for producing the same, and anti-inflammatory |
| RO117533B1 (en) * | 1993-05-14 | 2002-04-30 | Cytel Corp San Diego | ANALYTICAL SIALEL LEX DERIVATIVES CELLULAR ADHESIVE INHIBITORS AND PHARMACEUTICAL COMPOSITION WITH THIS ACTION |
| CN1176644A (en) * | 1994-12-28 | 1998-03-18 | 住友制药株式会社 | Lewis X derivative and process for producing the same |
-
1997
- 1997-08-06 AU AU43788/97A patent/AU720381B2/en not_active Ceased
- 1997-08-06 BR BR9711117-1A patent/BR9711117A/en not_active Application Discontinuation
- 1997-08-06 TR TR1999/00245T patent/TR199900245T2/en unknown
- 1997-08-06 PL PL97331286A patent/PL331286A1/en unknown
- 1997-08-06 IL IL12790897A patent/IL127908A0/en unknown
- 1997-08-06 NZ NZ334048A patent/NZ334048A/en unknown
- 1997-08-06 CN CN97197077A patent/CN1227563A/en active Pending
- 1997-08-06 SK SK156-99A patent/SK15699A3/en unknown
- 1997-08-06 WO PCT/EP1997/004279 patent/WO1998006730A1/en not_active Ceased
- 1997-08-06 CZ CZ99390A patent/CZ39099A3/en unknown
- 1997-08-06 KR KR1019997001025A patent/KR20000029862A/en not_active Withdrawn
- 1997-08-06 EP EP97941916A patent/EP0920437A1/en not_active Withdrawn
- 1997-08-06 AR ARP970103580A patent/AR008283A1/en unknown
- 1997-08-06 JP JP10509358A patent/JP2000516224A/en active Pending
- 1997-08-06 CA CA002260854A patent/CA2260854A1/en not_active Abandoned
- 1997-08-07 PE PE1997000688A patent/PE99298A1/en not_active Application Discontinuation
- 1997-08-08 CO CO97045596A patent/CO4900075A1/en unknown
- 1997-08-08 ID IDP972766A patent/ID18010A/en unknown
-
1999
- 1999-02-03 NO NO990497A patent/NO990497L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ39099A3 (en) | 1999-05-12 |
| ID18010A (en) | 1998-02-19 |
| NO990497L (en) | 1999-03-24 |
| CN1227563A (en) | 1999-09-01 |
| AU4378897A (en) | 1998-03-06 |
| CO4900075A1 (en) | 2000-03-27 |
| AR008283A1 (en) | 1999-12-29 |
| CA2260854A1 (en) | 1998-02-19 |
| AU720381B2 (en) | 2000-06-01 |
| SK15699A3 (en) | 1999-07-12 |
| NZ334048A (en) | 2000-05-26 |
| NO990497D0 (en) | 1999-02-03 |
| BR9711117A (en) | 1999-09-08 |
| IL127908A0 (en) | 1999-11-30 |
| EP0920437A1 (en) | 1999-06-09 |
| WO1998006730A1 (en) | 1998-02-19 |
| PE99298A1 (en) | 1999-01-21 |
| JP2000516224A (en) | 2000-12-05 |
| KR20000029862A (en) | 2000-05-25 |
| TR199900245T2 (en) | 1999-05-21 |
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