NO992705L - 3-pyridylenantiomere og deres anvendelse som analgetika - Google Patents

3-pyridylenantiomere og deres anvendelse som analgetika

Info

Publication number
NO992705L
NO992705L NO992705A NO992705A NO992705L NO 992705 L NO992705 L NO 992705L NO 992705 A NO992705 A NO 992705A NO 992705 A NO992705 A NO 992705A NO 992705 L NO992705 L NO 992705L
Authority
NO
Norway
Prior art keywords
analgesics
pyridylene
enantiomers
formula
compounds
Prior art date
Application number
NO992705A
Other languages
English (en)
Other versions
NO992705D0 (no
Inventor
Mark W Holladay
Stephen P Arneric
Hao Bai
Michael J Dart
Nan-Horng Lin
John K Lynch
Yat Sun Or
Keith B Ryther
James P Sullivan
James T Wasicak
Paul P Ehrlich
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO992705D0 publication Critical patent/NO992705D0/no
Publication of NO992705L publication Critical patent/NO992705L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO992705A 1996-12-10 1999-06-03 3-pyridylenantiomere og deres anvendelse som analgetika NO992705L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76327896A 1996-12-10 1996-12-10
US3232196P 1996-12-10 1996-12-10
PCT/US1997/022811 WO1998025920A1 (en) 1996-12-10 1997-12-10 3-pyridyl enantiomers and their use as analgesics

Publications (2)

Publication Number Publication Date
NO992705D0 NO992705D0 (no) 1999-06-03
NO992705L true NO992705L (no) 1999-08-03

Family

ID=26708255

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992705A NO992705L (no) 1996-12-10 1999-06-03 3-pyridylenantiomere og deres anvendelse som analgetika

Country Status (21)

Country Link
EP (1) EP0950057B1 (no)
JP (2) JP4272261B2 (no)
KR (2) KR100422995B1 (no)
CN (1) CN1125064C (no)
AT (1) ATE227717T1 (no)
AU (1) AU733881B2 (no)
BG (1) BG64196B1 (no)
BR (1) BR9714677A (no)
CA (2) CA2698384C (no)
DE (1) DE69717148T2 (no)
DK (1) DK0950057T3 (no)
ES (1) ES2189003T3 (no)
HU (1) HUP0001110A3 (no)
IL (1) IL130083A0 (no)
NO (1) NO992705L (no)
NZ (1) NZ335810A (no)
PL (1) PL333920A1 (no)
PT (1) PT950057E (no)
SK (1) SK75999A3 (no)
TR (1) TR199901904T2 (no)
WO (1) WO1998025920A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1068186A2 (en) 1998-04-02 2001-01-17 Targacept, Inc. Pharmaceutical compositions and methods for use
US6054451A (en) * 1998-04-21 2000-04-25 Algos Pharmaceutical Corporation Analgesic composition and method for alleviating pain
US6541669B1 (en) 1998-06-08 2003-04-01 Theravance, Inc. β2-adrenergic receptor agonists
US20010031771A1 (en) 1999-05-24 2001-10-18 Gary Maurice Dull Pharmaceutical compositions and methods for use
US6103911A (en) * 1999-06-15 2000-08-15 Abbott Laboratories Process for reduction of (2R)-4-oxoazetidinone-2-carboxylic acid
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2003097043A1 (en) * 2002-05-15 2003-11-27 Abbott Laboratories Treatment of neuropathic pain
EP1741709A1 (en) 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
WO2007065820A1 (en) 2005-12-09 2007-06-14 F. Hoffmann-La Roche Ag Tricyclic amide derivatives useful for treating obesity
TW200800020A (en) * 2006-01-26 2008-01-01 Basf Ag Methods to use 3-pyridyl derivatives as pesticides
US20100234349A1 (en) 2006-09-04 2010-09-16 Olsen Gunnar M Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer
DE102007058504A1 (de) 2007-12-05 2009-07-09 Acino Ag Transdermales therapeutisches System mit einem Gehalt an einem Modulator für nikotinische Acetylcholinrezeptoren (nAChR)
KR20110091501A (ko) 2008-10-14 2011-08-11 싸이코제닉스 아이엔씨. 니코틴성 아세틸콜린 수용체 리간드 및 이들의 용도
US8474529B2 (en) * 2009-04-09 2013-07-02 Regency Technologies Llc Control of concentric tubing direction
AR075988A1 (es) * 2009-04-09 2011-05-11 Lilly Co Eli Compuesto de piridiloxi - pirrolidina inhibidor de recaptacion de serotonina y norepinefrina, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para el tratamiento de dolor cronico
WO2013002365A1 (ja) 2011-06-30 2013-01-03 東レ株式会社 止痒剤
EP2983666B1 (en) * 2013-03-27 2019-10-09 Georgetown University 2-halo-5-alkynyl-pyridyl nicotinic ligands
EP3634528B1 (en) 2017-06-07 2023-06-07 Shifamed Holdings, LLC Intravascular fluid movement devices, systems, and methods of use
US11511103B2 (en) 2017-11-13 2022-11-29 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
EP3746149B1 (en) 2018-02-01 2025-08-06 Shifamed Holdings, LLC Intravascular blood pumps
WO2020028537A1 (en) 2018-07-31 2020-02-06 Shifamed Holdings, Llc Intravascaular blood pumps and methods of use
WO2020073047A1 (en) 2018-10-05 2020-04-09 Shifamed Holdings, Llc Intravascular blood pumps and methods of use
WO2021011473A1 (en) 2019-07-12 2021-01-21 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
US12465748B2 (en) 2019-08-07 2025-11-11 Supira Medical, Inc. Catheter blood pumps and collapsible pump housings
EP4501393A3 (en) 2019-09-25 2025-04-09 Shifamed Holdings, LLC Catheter blood pumps and collapsible pump housings
WO2021062260A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible blood conduits
US11724089B2 (en) 2019-09-25 2023-08-15 Shifamed Holdings, Llc Intravascular blood pump systems and methods of use and control thereof
EP4072650A4 (en) 2019-12-11 2024-01-10 Shifamed Holdings, LLC Descending aorta and vena cava blood pumps
EP4077947A4 (en) 2019-12-19 2024-01-10 Shifamed Holdings, LLC INTRAVASCULAR BLOOD PUMPS, MOTORS AND FLUID CONTROL

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8301702D0 (en) * 1983-01-21 1983-02-23 Shell Int Research Azetidine compounds
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
IL107184A (en) * 1992-10-09 1997-08-14 Abbott Lab Heterocyclic ether compounds that enhance cognitive function
US5585388A (en) * 1995-04-07 1996-12-17 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acetylcholine receptors
IL118279A (en) * 1995-06-07 2006-10-05 Abbott Lab Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission
US5629325A (en) * 1996-06-06 1997-05-13 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission

Also Published As

Publication number Publication date
BG103556A (en) 2000-06-30
DK0950057T3 (da) 2003-03-10
KR20040004476A (ko) 2004-01-13
CN1125064C (zh) 2003-10-22
DE69717148T2 (de) 2003-10-02
HUP0001110A3 (en) 2002-04-29
SK75999A3 (en) 2000-05-16
BG64196B1 (bg) 2004-04-30
PL333920A1 (en) 2000-01-31
AU733881B2 (en) 2001-05-31
CA2273917C (en) 2010-05-25
JP5364872B2 (ja) 2013-12-11
JP2009143924A (ja) 2009-07-02
NZ335810A (en) 2001-03-30
HUP0001110A2 (hu) 2001-04-28
KR20000069399A (ko) 2000-11-25
DE69717148D1 (de) 2002-12-19
EP0950057A1 (en) 1999-10-20
JP4272261B2 (ja) 2009-06-03
CA2698384C (en) 2012-05-01
CA2698384A1 (en) 1998-06-18
CA2273917A1 (en) 1998-06-18
WO1998025920A1 (en) 1998-06-18
AU5601098A (en) 1998-07-03
CN1245496A (zh) 2000-02-23
EP0950057B1 (en) 2002-11-13
BR9714677A (pt) 2000-10-03
PT950057E (pt) 2003-04-30
ATE227717T1 (de) 2002-11-15
KR100422995B1 (ko) 2004-03-12
KR100472154B1 (ko) 2005-02-21
ES2189003T3 (es) 2003-07-01
JP2001504857A (ja) 2001-04-10
NO992705D0 (no) 1999-06-03
TR199901904T2 (xx) 1999-10-21
IL130083A0 (en) 2000-02-29

Similar Documents

Publication Publication Date Title
DK0950057T3 (da) 3-pyridylenantiomerer og deres anvendelse som analgetika
BRPI0408784A (pt) método para usar um composto
DE69814394D1 (de) Verwendung von levobupivacain
EA200000723A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
DK1137762T3 (da) Behandling af Pompes sygdom
ES2144980T1 (es) Metodos y composiciones para tratar la rinitis alergica y otros trastornos, empleando descarboetoxiloratadina.
SE9604786D0 (sv) New compounds
BR0212252A (pt) Métodos para reduzir a hipertensão e a insuficiência cardìaca em um mamìfero
DK0723444T3 (da) Levobupivacain, som er egnet til behandling af kronisk smerte
ES2157957T3 (es) Procedimientos para inhibir la endometriosis.
NO990433L (no) Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet
DE60045508D1 (de) Dalda-analoge und ihre verwendung
MY119375A (en) Treatment of tinnitus using neuroprotective agents
BR0316458A (pt) Composto, composição farmacêutica, método de tratamento ou prevenção de doenças, método para intensificar a cognição em um paciente saudável, e, uso de um composto
NO994165L (no) Anvendelse av deskarboetoksyloratadin for fremstilling av et medikament for behandling av urininkontinens, reisesyke og svimmelhet
PT1039900E (pt) Agentes terapeuticos
BR9506552A (pt) Método de inibição de integrase retroviral
GR3025568T3 (en) Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia.
DK0986393T3 (da) Anvendelse af et nitroxid eller et prodrug heraf ved profylaktisk og terapeutisk behandling af cancer
NO991734L (no) Pyrazolinoner for behandling av potensforstyrrelser
MX9403032A (es) Quinolil-dihidropiridinas condensadas, procedimiento para su fabricacion ysu uso en medicamentos.
NO982863L (no) Nye forbindelser med analgetisk effekt
PT768083E (pt) Sertralina para o tratamento de doentes pos-enfarte miocardico
AU4937499A (en) Use of succinic acid or salts thereof and method of treating insulin resistance
DE69813681D1 (de) Neue triazole als therapeutische mittel gegen pilzinfektionen

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application