NO992873L - Diaza-spiro[3,5]nonan-derivater - Google Patents

Diaza-spiro[3,5]nonan-derivater

Info

Publication number
NO992873L
NO992873L NO992873A NO992873A NO992873L NO 992873 L NO992873 L NO 992873L NO 992873 A NO992873 A NO 992873A NO 992873 A NO992873 A NO 992873A NO 992873 L NO992873 L NO 992873L
Authority
NO
Norway
Prior art keywords
diaza
spiro
nonane derivatives
nonane
derivatives
Prior art date
Application number
NO992873A
Other languages
English (en)
Other versions
NO312590B1 (no
NO992873D0 (no
Inventor
Geo Adam
Andrea Cesura
Francois Jenck
Sabine Kolczewski
Stephan Roever
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO992873D0 publication Critical patent/NO992873D0/no
Publication of NO992873L publication Critical patent/NO992873L/no
Publication of NO312590B1 publication Critical patent/NO312590B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
NO19992873A 1998-06-12 1999-06-11 Diaza-spiro[3,5]nonan-derivater, fremgangsmåte til fremstilling og anvendelse av dem, og medikamenter inneholdendedem NO312590B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98110804 1998-06-12

Publications (3)

Publication Number Publication Date
NO992873D0 NO992873D0 (no) 1999-06-11
NO992873L true NO992873L (no) 1999-12-13
NO312590B1 NO312590B1 (no) 2002-06-03

Family

ID=8232114

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19992873A NO312590B1 (no) 1998-06-12 1999-06-11 Diaza-spiro[3,5]nonan-derivater, fremgangsmåte til fremstilling og anvendelse av dem, og medikamenter inneholdendedem

Country Status (28)

Country Link
US (1) US6113527A (no)
EP (1) EP0970957B1 (no)
JP (1) JP3286268B2 (no)
KR (1) KR100344732B1 (no)
CN (1) CN1107066C (no)
AR (1) AR019859A1 (no)
AT (1) ATE204279T1 (no)
AU (1) AU743983B2 (no)
BR (1) BR9902651A (no)
CA (1) CA2274202A1 (no)
DE (1) DE69900220T2 (no)
DK (1) DK0970957T3 (no)
ES (1) ES2162503T3 (no)
HR (1) HRP990188A2 (no)
HU (1) HU220894B1 (no)
ID (1) ID23304A (no)
IL (1) IL130377A0 (no)
MA (1) MA26644A1 (no)
NO (1) NO312590B1 (no)
NZ (1) NZ336189A (no)
PE (1) PE20000548A1 (no)
PL (1) PL333695A1 (no)
PT (1) PT970957E (no)
SG (1) SG79259A1 (no)
SI (1) SI0970957T1 (no)
TR (1) TR199901381A2 (no)
YU (1) YU26499A (no)
ZA (1) ZA993852B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030040479A1 (en) * 2001-07-02 2003-02-27 Omeros Corporation Rotational intrathecal analgesia method and device
WO2003004034A1 (en) * 2001-07-02 2003-01-16 Omeros Corporation Method for inducing analgesia comprising administration alternatively of an opioid receptor agonist and an opioid receptor like receptor 1 agonist for and an implantable infusion pump
US7566728B2 (en) 2002-03-29 2009-07-28 Mitsubishi Tanabe Pharma Corporation Remedy for sleep disturbance
JP2005289816A (ja) 2002-05-14 2005-10-20 Banyu Pharmaceut Co Ltd ベンズイミダゾール誘導体
PT1519939E (pt) * 2002-07-05 2010-02-10 Targacept Inc Compostos n-arildiazaspirocíclicos e métodos para a sua preparação e utilização
AU2003268512A1 (en) * 2002-09-09 2004-03-29 Janssen Pharmaceutica N.V. Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
GB0323204D0 (en) * 2003-10-03 2003-11-05 Novartis Ag Organic compounds
WO2005060947A2 (en) * 2003-12-19 2005-07-07 Sri International Agonist and antagonist ligands of the nociceptin receptor
US20060178390A1 (en) * 2004-08-02 2006-08-10 Alfonzo Jordan 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
JP2008510711A (ja) * 2004-08-20 2008-04-10 ターガセプト，インコーポレイテッド 嗜癖治療におけるｎ−アリールジアザスピラ環状化合物の使用
US20080247964A1 (en) * 2006-05-08 2008-10-09 Yuelian Xu Substituted azaspiro derivatives
CN103202840B (zh) * 2006-11-28 2015-02-11 詹森药业有限公司 3-(3-氨基-2-(r)-羟基-丙基)-1-(4-氟-苯基)-8-(8-甲基-萘-1-基甲基)-1,3,8-三氮杂-螺[4.5]癸烷-4-酮的盐
EP2150552B1 (en) * 2007-04-09 2013-01-02 Janssen Pharmaceutica NV 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression
KR101704226B1 (ko) 2015-06-30 2017-02-07 현대자동차주식회사 자동차의 쿼터글라스 어셈블리
AU2022421224A1 (en) * 2021-12-22 2024-06-20 The Regents Of The University Of California Covalently binding inhibitors of g12s, g12d and/or g12e mutants of k-ras gtpase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756743A (en) * 1996-04-10 1998-05-26 Hoechst Marion Roussel Inc. Spiro cyclopent b!indole-piperidines!

Also Published As

Publication number Publication date
HU220894B1 (en) 2002-06-29
HU9901911D0 (en) 1999-08-30
EP0970957A1 (en) 2000-01-12
SI0970957T1 (no) 2001-12-31
HUP9901911A1 (hu) 2000-05-28
YU26499A (sh) 2002-09-19
CA2274202A1 (en) 1999-12-12
TR199901381A3 (tr) 2000-01-21
DK0970957T3 (da) 2001-12-03
EP0970957B1 (en) 2001-08-16
IL130377A0 (en) 2000-06-01
MA26644A1 (fr) 2004-12-20
NZ336189A (en) 2000-10-27
AU3498799A (en) 1999-12-23
HRP990188A2 (en) 2000-02-29
PT970957E (pt) 2002-02-28
BR9902651A (pt) 2000-05-16
CN1242366A (zh) 2000-01-26
ZA993852B (en) 1999-12-13
CN1107066C (zh) 2003-04-30
JP3286268B2 (ja) 2002-05-27
US6113527A (en) 2000-09-05
AU743983B2 (en) 2002-02-14
ATE204279T1 (de) 2001-09-15
DE69900220T2 (de) 2002-05-08
TR199901381A2 (xx) 2000-01-21
JP2000053679A (ja) 2000-02-22
KR20000006060A (ko) 2000-01-25
AR019859A1 (es) 2002-03-20
PE20000548A1 (es) 2000-07-15
NO312590B1 (no) 2002-06-03
ES2162503T3 (es) 2001-12-16
NO992873D0 (no) 1999-06-11
KR100344732B1 (ko) 2002-07-19
DE69900220D1 (de) 2001-09-20
PL333695A1 (en) 1999-12-20
ID23304A (id) 2000-04-05
SG79259A1 (en) 2001-03-20

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