NO992976L - Heterocykliske karboksylsyre-derivater, fremstilling og anvendelse derav som endothelinreseptor-antagonister - Google Patents
Heterocykliske karboksylsyre-derivater, fremstilling og anvendelse derav som endothelinreseptor-antagonisterInfo
- Publication number
- NO992976L NO992976L NO992976A NO992976A NO992976L NO 992976 L NO992976 L NO 992976L NO 992976 A NO992976 A NO 992976A NO 992976 A NO992976 A NO 992976A NO 992976 L NO992976 L NO 992976L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- carboxylic acid
- acid derivatives
- receptor antagonists
- endothelin receptor
- Prior art date
Links
- 229940118365 Endothelin receptor antagonist Drugs 0.000 title 1
- -1 Heterocyclic carboxylic acid derivatives Chemical class 0.000 title 1
- 239000002308 endothelin receptor antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
- C07D237/16—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1996152763 DE19652763A1 (de) | 1996-12-18 | 1996-12-18 | Heterozyklische Carbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten |
| DE1997100884 DE19700884A1 (de) | 1997-01-13 | 1997-01-13 | Heterozyklische Carbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten |
| PCT/EP1997/006778 WO1998027070A1 (de) | 1996-12-18 | 1997-12-04 | Heterozyklische carbonsäurederivate, ihre herstellung und verwendung als endothelinrezeptorantagonisten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO992976D0 NO992976D0 (no) | 1999-06-17 |
| NO992976L true NO992976L (no) | 1999-06-17 |
| NO313519B1 NO313519B1 (no) | 2002-10-14 |
Family
ID=26032394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19992976A NO313519B1 (no) | 1996-12-18 | 1999-06-17 | Heterocykliske karboksylsyre-derivater, preparater inneholdende dem, og anvendelse av dem til fremstilling av slikepreparater |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6448248B1 (no) |
| EP (1) | EP0946524A1 (no) |
| JP (1) | JP2001506243A (no) |
| KR (1) | KR20000057642A (no) |
| CN (1) | CN1247533A (no) |
| AR (1) | AR010359A1 (no) |
| AU (1) | AU740351B2 (no) |
| BG (1) | BG103502A (no) |
| BR (1) | BR9714047A (no) |
| CA (1) | CA2275256A1 (no) |
| CO (1) | CO4930270A1 (no) |
| HR (1) | HRP970686A2 (no) |
| HU (1) | HUP0000553A3 (no) |
| ID (1) | ID26234A (no) |
| IL (1) | IL130251A0 (no) |
| NO (1) | NO313519B1 (no) |
| NZ (1) | NZ336157A (no) |
| PL (1) | PL334014A1 (no) |
| SK (1) | SK77799A3 (no) |
| TR (1) | TR199901416T2 (no) |
| WO (1) | WO1998027070A1 (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4917707B2 (ja) * | 1997-09-26 | 2012-04-18 | アボット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | エンドセリン拮抗剤およびレニン−アンギオテンシン系阻害剤から成る組合せ剤 |
| DE19743143A1 (de) | 1997-09-30 | 1999-04-01 | Knoll Ag | Pharmazeutische Kombinationspräparate |
| ES2238770T5 (es) * | 1997-10-17 | 2012-01-17 | Ark Therapeutics Limited | Utilización de inhibidores del sistema renina-angiotensina para el tratamiento de la hipoxia o de la disminución de la función metabólica. |
| DE19806438A1 (de) * | 1998-02-17 | 1999-08-19 | Basf Ag | Neue Carbonsäurederivate mit 5-substituiertem Pyrimidinring, ihre Herstellung und Verwendung |
| DE19858779A1 (de) * | 1998-12-18 | 2000-06-21 | Basf Ag | Neue ß-Amido und ß-Sulfonamidocarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten |
| DE19924892A1 (de) * | 1999-06-01 | 2000-12-07 | Basf Ag | Neue Carbonsäurederivate mit arylsubstituierten Stickstoffheterocyclen, ihre Herstellung und Verwendung als Endothelin Rezeptorantagonisten |
| IL148841A0 (en) * | 1999-10-06 | 2002-09-12 | Basf Ag | INHIBITORS OF THE ENDOTHELIN SIGNALLING PATHWAY AND αvβ3 INTEGRIN RECEPTOR ANTAGONISTS FOR COMBINATION THERAPY |
| DE10101307A1 (de) * | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
| FI20010233A0 (fi) * | 2001-02-08 | 2001-02-08 | Orion Corp | Menetelmä sydämen vajaatoiminnan hoitoon |
| WO2003006041A1 (fr) * | 2001-07-12 | 2003-01-23 | Takeda Chemical Industries, Ltd. | Agents prophylactiques/therapeutiques contre les tumeurs malignes |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2671551B1 (fr) * | 1991-01-15 | 1993-03-12 | Adir | Nouveaux composes de structure aryl triazinique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| DE19533023B4 (de) * | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
| DE19614534A1 (de) | 1996-04-12 | 1997-10-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
| DE19614533A1 (de) * | 1996-04-12 | 1997-10-16 | Basf Ag | Neue alpha-Hydroxysäurederivate, ihre Herstellung und Verwendung |
| DE19614542A1 (de) * | 1996-04-12 | 1997-10-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
-
1997
- 1997-12-04 US US09/319,876 patent/US6448248B1/en not_active Expired - Fee Related
- 1997-12-04 ID IDW990558A patent/ID26234A/id unknown
- 1997-12-04 EP EP97952876A patent/EP0946524A1/de not_active Withdrawn
- 1997-12-04 KR KR1019990705445A patent/KR20000057642A/ko not_active Withdrawn
- 1997-12-04 TR TR1999/01416T patent/TR199901416T2/xx unknown
- 1997-12-04 CN CN97181869A patent/CN1247533A/zh active Pending
- 1997-12-04 BR BR9714047-3A patent/BR9714047A/pt not_active IP Right Cessation
- 1997-12-04 SK SK777-99A patent/SK77799A3/sk unknown
- 1997-12-04 PL PL97334014A patent/PL334014A1/xx unknown
- 1997-12-04 NZ NZ336157A patent/NZ336157A/xx unknown
- 1997-12-04 WO PCT/EP1997/006778 patent/WO1998027070A1/de not_active Ceased
- 1997-12-04 IL IL13025197A patent/IL130251A0/xx unknown
- 1997-12-04 JP JP52724798A patent/JP2001506243A/ja active Pending
- 1997-12-04 CA CA002275256A patent/CA2275256A1/en not_active Abandoned
- 1997-12-04 HU HU0000553A patent/HUP0000553A3/hu unknown
- 1997-12-04 AU AU56594/98A patent/AU740351B2/en not_active Ceased
- 1997-12-16 AR ARP970105907A patent/AR010359A1/es not_active Application Discontinuation
- 1997-12-16 HR HR19700884.4A patent/HRP970686A2/hr not_active Application Discontinuation
- 1997-12-17 CO CO97073662A patent/CO4930270A1/es unknown
-
1999
- 1999-06-17 NO NO19992976A patent/NO313519B1/no not_active IP Right Cessation
- 1999-06-18 BG BG103502A patent/BG103502A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001506243A (ja) | 2001-05-15 |
| ID26234A (id) | 2000-12-07 |
| WO1998027070A1 (de) | 1998-06-25 |
| TR199901416T2 (xx) | 1999-08-23 |
| CN1247533A (zh) | 2000-03-15 |
| BR9714047A (pt) | 2000-05-09 |
| HUP0000553A3 (en) | 2001-08-28 |
| CO4930270A1 (es) | 2000-06-27 |
| KR20000057642A (ko) | 2000-09-25 |
| NZ336157A (en) | 2000-10-27 |
| CA2275256A1 (en) | 1998-06-25 |
| AU5659498A (en) | 1998-07-15 |
| NO992976D0 (no) | 1999-06-17 |
| AU740351B2 (en) | 2001-11-01 |
| EP0946524A1 (de) | 1999-10-06 |
| SK77799A3 (en) | 2000-02-14 |
| NO313519B1 (no) | 2002-10-14 |
| AR010359A1 (es) | 2000-06-07 |
| US6448248B1 (en) | 2002-09-10 |
| IL130251A0 (en) | 2000-06-01 |
| HUP0000553A1 (hu) | 2001-04-28 |
| HRP970686A2 (en) | 1998-10-31 |
| BG103502A (en) | 2000-07-31 |
| PL334014A1 (en) | 2000-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JUNE 2003 |