NO994106L - Oksazolidiner som 5-HT2A-antagonister - Google Patents

Oksazolidiner som 5-HT2A-antagonister

Info

Publication number
NO994106L
NO994106L NO994106A NO994106A NO994106L NO 994106 L NO994106 L NO 994106L NO 994106 A NO994106 A NO 994106A NO 994106 A NO994106 A NO 994106A NO 994106 L NO994106 L NO 994106L
Authority
NO
Norway
Prior art keywords
oxazolidines
antagonists
Prior art date
Application number
NO994106A
Other languages
English (en)
Other versions
NO994106D0 (no
NO313415B1 (no
Inventor
Henning Boettcher
Helmut Pruecher
Helmut Greiner
Gerd Bartoszyk
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO994106D0 publication Critical patent/NO994106D0/no
Publication of NO994106L publication Critical patent/NO994106L/no
Publication of NO313415B1 publication Critical patent/NO313415B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO19994106A 1997-02-26 1999-08-25 Oksazolidiner, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstilling derav,forbindelsene 5-HT2A-antagonister, samt anvendelse avforbindelsene til fremstilling av legemidler NO313415B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19707628A DE19707628A1 (de) 1997-02-26 1997-02-26 Oxazolidinone
PCT/EP1998/000637 WO1998038189A1 (de) 1997-02-26 1998-02-06 Oxazolidinone als 5-ht2a-antagonisten

Publications (3)

Publication Number Publication Date
NO994106D0 NO994106D0 (no) 1999-08-25
NO994106L true NO994106L (no) 1999-10-19
NO313415B1 NO313415B1 (no) 2002-09-30

Family

ID=7821498

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19994106A NO313415B1 (no) 1997-02-26 1999-08-25 Oksazolidiner, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstilling derav,forbindelsene 5-HT2A-antagonister, samt anvendelse avforbindelsene til fremstilling av legemidler

Country Status (25)

Country Link
US (1) US6462056B1 (no)
EP (1) EP0964863B1 (no)
JP (2) JP4402175B2 (no)
KR (1) KR20000075697A (no)
CN (1) CN1177847C (no)
AR (1) AR010899A1 (no)
AT (1) ATE240954T1 (no)
AU (1) AU739251B2 (no)
BR (1) BR9807765A (no)
CA (1) CA2281918C (no)
CZ (1) CZ299199A3 (no)
DE (2) DE19707628A1 (no)
DK (1) DK0964863T3 (no)
ES (1) ES2197466T3 (no)
HU (1) HUP0001093A3 (no)
ID (1) ID22838A (no)
NO (1) NO313415B1 (no)
PL (1) PL335100A1 (no)
PT (1) PT964863E (no)
RU (1) RU2196140C2 (no)
SK (1) SK112799A3 (no)
TW (1) TW531538B (no)
UA (1) UA58542C2 (no)
WO (1) WO1998038189A1 (no)
ZA (1) ZA981579B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787328A1 (fr) * 1998-12-22 2000-06-23 Sanofi Sa Utilisation d'un antagoniste des recepteurs 5ht2a pour la preparation de medicaments utiles dans le traitement des ronflements et du syndrome de haute resistance ou de resistance des voies aeriennes superieures
TR200101939T2 (tr) * 1999-01-28 2002-05-21 Bristol-Myers Squibb Company Antidepresan heterosiklik bileşikler
ES2165274B1 (es) 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
EP1106605A4 (en) * 1999-06-24 2005-12-07 Toray Industries ANTAGONISTS OF THE ADRENERGIC RECEPTOR-ALPHA1B
GB9928568D0 (en) * 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2002081470A1 (en) * 2001-04-07 2002-10-17 Astrazeneca Ab Oxazolidinones containing a sulfonimid group as antibiotics
MXPA04007067A (es) * 2002-01-22 2004-11-01 Upjohn Co Dispositivos medicos resistentes a infecciones.
JPWO2004069828A1 (ja) * 2003-02-04 2006-05-25 三菱ウェルファーマ株式会社 ピペリジン化合物およびその医薬用途
WO2005060968A1 (en) 2003-12-11 2005-07-07 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
CL2008001002A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
RU2492169C2 (ru) * 2007-12-18 2013-09-10 Актелион Фармасьютиклз Лтд Производные 5-аминоциклилметилоксазолидин-2-она
MX2011003188A (es) * 2008-10-10 2011-04-27 Actelion Pharmaceuticals Ltd Antibioticos de oxazolidinilo.
WO2014046544A1 (en) 2012-09-21 2014-03-27 Aapa B.V. Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3723797A1 (de) * 1987-07-18 1989-01-26 Merck Patent Gmbh Oxazolidinone
DE4005371A1 (de) * 1990-02-21 1991-08-22 Merck Patent Gmbh Oxazolidinone
DE4017211A1 (de) * 1990-05-29 1991-12-05 Merck Patent Gmbh Oxazolidinone
DK152090D0 (da) 1990-06-22 1990-06-22 Lundbaek A S H Piperidylsubstituerede indolderivater
DK158590D0 (da) * 1990-07-02 1990-07-02 Lundbeck & Co As H Indolderivater
CA2100376A1 (en) * 1992-07-14 1994-01-15 Mitsuo Masaki Alkylenediamine derivatives
DE4324393A1 (de) * 1993-07-21 1995-01-26 Merck Patent Gmbh 4-Aryloxy- und 4-Arylthiopiperidinderivate
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
IL114026A (en) * 1994-06-08 1999-06-20 Lundbeck & Co As H 4-aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzo thiophenemethyl) piperidines tetrahydropyridines or piperazines and pharmaceutical compositions containing them
DE19500689A1 (de) * 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate

Also Published As

Publication number Publication date
ATE240954T1 (de) 2003-06-15
HUP0001093A3 (en) 2001-07-30
TW531538B (en) 2003-05-11
NO994106D0 (no) 1999-08-25
CA2281918C (en) 2007-04-03
CA2281918A1 (en) 1998-09-03
PL335100A1 (en) 2000-04-10
JP2001513764A (ja) 2001-09-04
DE59808461D1 (de) 2003-06-26
RU2196140C2 (ru) 2003-01-10
AR010899A1 (es) 2000-07-12
JP4402175B2 (ja) 2010-01-20
KR20000075697A (ko) 2000-12-26
US6462056B1 (en) 2002-10-08
CN1177847C (zh) 2004-12-01
DK0964863T3 (da) 2003-08-04
DE19707628A1 (de) 1998-08-27
AU739251B2 (en) 2001-10-04
UA58542C2 (uk) 2003-08-15
AU6394998A (en) 1998-09-18
SK112799A3 (en) 2000-06-12
EP0964863A1 (de) 1999-12-22
JP2009256363A (ja) 2009-11-05
WO1998038189A1 (de) 1998-09-03
CN1248973A (zh) 2000-03-29
ES2197466T3 (es) 2004-01-01
EP0964863B1 (de) 2003-05-21
HUP0001093A2 (hu) 2001-06-28
ID22838A (id) 1999-12-09
BR9807765A (pt) 2000-02-22
ZA981579B (en) 1999-03-17
NO313415B1 (no) 2002-09-30
CZ299199A3 (cs) 1999-11-17
PT964863E (pt) 2003-10-31

Similar Documents

Publication Publication Date Title
NO985225D0 (no) Indolderivater nyttige som endotelinreseptorantagonister
IT1308096B1 (it) Convertiplano
DK2253620T3 (da) Substituerede 3-cyanoquinoliner som protein-tyrosinkinase-inhibitorer
NO20012948L (no) Hydroksydifenylureasulfonamider som IL-8 reseptor antagonister
IT1298518B1 (it) Alesatore
EP0986385A4 (en) GONADORELIN ANTAGONISTS
IS2027B (is) Ný spíróasabísýklísk heterósýklísk efnasambönd
DK0856001T3 (da) Pyrimidinderivater som 5-HT2C-receptor-antagonister
DK0736525T3 (da) Benzonitriler som 5-HT-agonister og -antagonister
NO991384D0 (no) Substituerte heterocykler som anti-tumormidler
DK0975623T3 (da) Indazolamidforbindelser som sertoninerge midler
NO994106D0 (no) Oksazolidiner som 5-HT2A-antagonister
DE50009640D1 (de) Drehmaschine
DK0906294T3 (da) Benzoxazinon-dopamin D4-receptor-antagonister
DK1027342T3 (da) Cyclopentenderivater som motilinreceptorantagonister
NO20021251D0 (no) Tienoisoksazolyl- og tienylpyrrazolyl-fenoksysubstituerte propylderivater anvendelige som D4antagonister
DK1075471T3 (da) Idolylderivater som serotonerge midler
DK1086093T3 (da) Tetrahydroquinolinderivater som glycinantagonister
NO992066D0 (no) Piperazinoderivater som neurokininantagonister
NO20000434D0 (no) Lyksofuranosyl benzimidazoler som antivirale midler
NO985972D0 (no) Indolinderivater anvendelige som 5-HT-2C reseptorantagonister
NO993172D0 (no) Sulfonamid-forbindelser med 5-HT-reseptor-aktivitet
NO20002575D0 (no) Substituerte oksimer som neurokininantagonister
DK0944601T3 (da) Heterocykliske quanidinylaminoforbindelser som alfa-2-adrenoceptoragonister
PT960100E (pt) 4-benzoilpirazois substituidos

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees