NO994977L - Fremstilling av enantiomerfrie biarylketokarboksylsyrer - Google Patents

Fremstilling av enantiomerfrie biarylketokarboksylsyrer

Info

Publication number
NO994977L
NO994977L NO994977A NO994977A NO994977L NO 994977 L NO994977 L NO 994977L NO 994977 A NO994977 A NO 994977A NO 994977 A NO994977 A NO 994977A NO 994977 L NO994977 L NO 994977L
Authority
NO
Norway
Prior art keywords
enantiomer
preparation
free
acids
biarylketocarboxylic
Prior art date
Application number
NO994977A
Other languages
English (en)
Other versions
NO994977D0 (no
Inventor
Michael Preiss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO994977L publication Critical patent/NO994977L/no
Publication of NO994977D0 publication Critical patent/NO994977D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Foreliggende oppfinnelse vedrører en kontinuerlig fremgangsmåte for fremstilling av enantiomerfrie biarylketokarboksylsyrer, hvorved S-fenyletylamin anvendes som hjelpebase i oppløsningen. Biarylketokarboksylsyrer, spesielt substituerte biaryl-4- ketokarboksylsyrer, er inhibitorer av enzymer fra klassen av matriks-metallo-proteinaser. Ved inhibering av ovennevnte enzymer er det mulig å bekjempe osteoartritt, reumatoid artritt og metastaser.
NO994977A 1997-04-25 1999-10-13 Fremstilling av enantiomerfrie biarylketokarboksylsyrer NO994977D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19717429A DE19717429A1 (de) 1997-04-25 1997-04-25 Herstellung enantiomerenreiner Biarylketocarbonsäuren
PCT/EP1998/002176 WO1998049124A1 (de) 1997-04-25 1998-04-14 Herstellung enantiomerenreiner biarylketocarbonsäuren

Publications (2)

Publication Number Publication Date
NO994977L true NO994977L (no) 1999-10-13
NO994977D0 NO994977D0 (no) 1999-10-13

Family

ID=7827688

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994977A NO994977D0 (no) 1997-04-25 1999-10-13 Fremstilling av enantiomerfrie biarylketokarboksylsyrer

Country Status (22)

Country Link
US (1) US6172259B1 (no)
EP (1) EP0977717A1 (no)
JP (1) JP2001524102A (no)
KR (1) KR20010020236A (no)
CN (1) CN1253539A (no)
AR (1) AR012440A1 (no)
AU (1) AU730250B2 (no)
BG (1) BG103776A (no)
BR (1) BR9809418A (no)
CA (1) CA2288107A1 (no)
CO (1) CO4940428A1 (no)
DE (1) DE19717429A1 (no)
HU (1) HUP0003633A3 (no)
ID (1) ID22701A (no)
IL (1) IL132065A0 (no)
NO (1) NO994977D0 (no)
PL (1) PL336323A1 (no)
SK (1) SK145999A3 (no)
TR (1) TR199902451T2 (no)
TW (1) TW382622B (no)
WO (1) WO1998049124A1 (no)
ZA (1) ZA983473B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8768754B2 (en) * 2006-01-09 2014-07-01 Rent-A-Toll, Ltd. Billing a rented third party transport including an on-board unit

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS222255B2 (en) * 1977-03-08 1983-06-24 Boots Co Ltd Method of increasing the portion of the deisred anantiometer in the acid component of the 2-arylpropion acid
IT1222013B (it) * 1987-07-10 1990-08-31 Chimica Profarmaco Spa Ind Processo di risoluzione ottica di acido 2 (6 metossi 2 naftil) propionico
DE3824353A1 (de) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
CA2023954C (en) 1989-10-17 1999-05-04 Hiroyuki Nohira Process for the optical resolution of 2-(3-benzoyl) phenylpropionic acid
JP3574954B2 (ja) * 1993-11-26 2004-10-06 ナガセケムテックス株式会社 ２−アリールプロピオン酸化合物の光学分割方法
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors

Also Published As

Publication number Publication date
CO4940428A1 (es) 2000-07-24
TW382622B (en) 2000-02-21
ID22701A (id) 1999-12-09
SK145999A3 (en) 2000-05-16
BR9809418A (pt) 2000-06-13
BG103776A (en) 2000-05-31
TR199902451T2 (xx) 2000-04-21
NO994977D0 (no) 1999-10-13
JP2001524102A (ja) 2001-11-27
KR20010020236A (ko) 2001-03-15
IL132065A0 (en) 2001-03-19
CN1253539A (zh) 2000-05-17
AR012440A1 (es) 2000-10-18
AU7525198A (en) 1998-11-24
PL336323A1 (en) 2000-06-19
HUP0003633A3 (en) 2001-04-28
CA2288107A1 (en) 1998-11-05
WO1998049124A1 (de) 1998-11-05
DE19717429A1 (de) 1998-12-24
EP0977717A1 (de) 2000-02-09
AU730250B2 (en) 2001-03-01
ZA983473B (en) 1998-10-29
HUP0003633A2 (en) 2001-03-28
US6172259B1 (en) 2001-01-09

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