NO995783L - Nye cykliske diaminforbindelser og medisiner inneholdende de samme - Google Patents

Nye cykliske diaminforbindelser og medisiner inneholdende de samme

Info

Publication number
NO995783L
NO995783L NO995783A NO995783A NO995783L NO 995783 L NO995783 L NO 995783L NO 995783 A NO995783 A NO 995783A NO 995783 A NO995783 A NO 995783A NO 995783 L NO995783 L NO 995783L
Authority
NO
Norway
Prior art keywords
optionally substituted
lower alkyl
alkyl group
integer
present
Prior art date
Application number
NO995783A
Other languages
English (en)
Other versions
NO315045B1 (no
NO995783D0 (no
Inventor
Kimiyuki Shibuya
Katsumi Kawamine
Yukihiro Sato
Toru Miura
Chiyoka Ozaki
Toshiyuki Edano
Mitsuteru Hirata
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Publication of NO995783D0 publication Critical patent/NO995783D0/no
Publication of NO995783L publication Critical patent/NO995783L/no
Publication of NO315045B1 publication Critical patent/NO315045B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70—Sulfur atoms
    • C07D277/74—Sulfur atoms substituted by carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19995783A 1997-05-26 1999-11-25 Nye cykliske diaminforbindelser og medisiner inneholdende de samme NO315045B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14989297 1997-05-26
PCT/JP1998/002300 WO1998054153A1 (en) 1997-05-26 1998-05-26 Novel cyclic diamine compounds and medicine containing the same

Publications (3)

Publication Number Publication Date
NO995783D0 NO995783D0 (no) 1999-11-25
NO995783L true NO995783L (no) 2000-01-26
NO315045B1 NO315045B1 (no) 2003-06-30

Family

ID=15484915

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19995783A NO315045B1 (no) 1997-05-26 1999-11-25 Nye cykliske diaminforbindelser og medisiner inneholdende de samme

Country Status (19)

Country Link
EP (1) EP0987254B1 (no)
JP (1) JP3614865B2 (no)
KR (1) KR100549804B1 (no)
CN (1) CN1118457C (no)
AT (1) ATE285402T1 (no)
AU (1) AU728151B2 (no)
CA (1) CA2290744C (no)
CZ (1) CZ297451B6 (no)
DE (1) DE69828276T2 (no)
ES (1) ES2235328T3 (no)
HU (1) HUP0002294A3 (no)
ID (1) ID23377A (no)
NO (1) NO315045B1 (no)
NZ (1) NZ501156A (no)
PT (1) PT987254E (no)
RU (1) RU2207341C2 (no)
SK (1) SK284891B6 (no)
TW (1) TW589308B (no)
WO (1) WO1998054153A1 (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
EP1086948A4 (en) * 1998-02-25 2004-03-10 Sumitomo Pharma PYRIDONE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
ATE257826T1 (de) * 1999-06-28 2004-01-15 Fuji Photo Film Co Ltd Benzimidazolderivate und sie enthaltende medikamente
EP1201664B1 (en) * 1999-06-30 2004-09-08 Fuji Photo Film Co., Ltd. Benzimidazole compounds and drugs containing the same
JP4624616B2 (ja) * 1999-07-07 2011-02-02 富士フイルム株式会社 ベンズイミダゾール化合物
WO2003018564A1 (en) * 2001-08-22 2003-03-06 Kowa Company, Ltd Vascular wall-selective acat inhibitor
US20060165605A1 (en) 2001-12-28 2006-07-27 Ye-Mon Chen Process to regenerate fcc spent catalyst
JP4571505B2 (ja) * 2002-11-28 2010-10-27 興和株式会社 1−[2−(ベンズイミダゾール−2−イルチオ)エチル]ピペラジン又はその塩の製造法
ES2287574T3 (es) * 2002-12-05 2007-12-16 Cv Therapeutics, Inc. Compuestos de piperacina sustituidos y su utilizacion como inhibidores de la oxidacion de acidos grasos.
EP1571144A4 (en) 2002-12-12 2007-08-01 Kowa Co HYDROXYALKYLATED CYCLIC DEDIAMINE COMPOUND
MY140618A (en) * 2003-02-28 2009-12-31 Kowa Co Method for preparing acid addition salts of polyacidic basic compounds
WO2004099179A1 (en) * 2003-05-07 2004-11-18 Actelion Pharmaceuticals Ltd Piperazine-alkyl-ureido derivatives
WO2004106323A1 (ja) * 2003-05-28 2004-12-09 Kowa Co., Ltd. 環状ジアミン誘導体又はその塩の製造法
MY140849A (en) * 2003-07-07 2010-01-29 Kowa Co 2, 4-bis (trifluoroethoxy) pyridine compound and drug containing the compound
NZ544803A (en) * 2003-08-29 2009-11-27 Kowa Co Method of stabilizing lipid-rich plaque and method of preventing rupture thereof
EP1689383B1 (en) 2003-11-19 2012-10-31 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US7163944B2 (en) * 2004-01-26 2007-01-16 Kowa Co., Ltd. Cyclic diamine compound and pharmaceutical containing the same
JPWO2006003974A1 (ja) * 2004-06-30 2008-04-17 興和株式会社 環状ジアミン誘導体の製造法
CA2576170A1 (en) * 2004-08-16 2006-03-02 The Procter & Gamble Company 2-(amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof
KR101021828B1 (ko) 2004-10-27 2011-03-17 다이이찌 산쿄 가부시키가이샤 2 이상의 치환기를 갖는 벤젠 화합물
TW200619204A (en) 2004-12-10 2006-06-16 Kowa Co Method for reduction, stabilization and prevention of rupture of lipid rich plaque
FR2920774B1 (fr) * 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de n-phenul acatamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contentant
FR2920770B1 (fr) * 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de phenylurees, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant
FR2920769B1 (fr) 2007-09-06 2009-10-30 Galderma Res & Dev Nouveaux derives de n-phenyl acetamide, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant
JP5291979B2 (ja) 2008-04-24 2013-09-18 株式会社フジクラ 圧力センサ及びその製造方法と、該圧力センサを備えた電子部品
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
JPWO2011081117A1 (ja) * 2009-12-29 2013-05-09 興和株式会社 経口投与用固形医薬組成物
US20130035344A1 (en) * 2009-12-29 2013-02-07 Kowa Co., Ltd. Pharmaceutical composition for oral administration
WO2011145340A1 (ja) 2010-05-19 2011-11-24 興和株式会社 非アルコール性脂肪性肝炎の予防及び/又は治療剤
JP2016521259A (ja) * 2013-03-20 2016-07-21 バイエル・ファルマ・アクティエンゲゼルシャフト 置換N−ビフェニル−3−アセチルアミノ−ベンズアミドおよびN−[3−(アセチルアミノ)フェニル]−ビフェニル−カルボキサミドならびにWntシグナル伝達経路の阻害剤としてのそれらの使用
CN105693524A (zh) * 2014-11-28 2016-06-22 浙江省化工研究院有限公司 一种硝基化合物的制备方法
WO2018097149A1 (ja) * 2016-11-24 2018-05-31 帝人ファーマ株式会社 スルフィド化合物の製造方法

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Publication number Priority date Publication date Assignee Title
US3629208A (en) * 1969-06-18 1971-12-21 Monsanto Co N-aminoalkyl thiazolesulfenamides as vulcanization accelerators
DD290192A5 (de) * 1986-11-13 1991-05-23 Eisai Co. Ltd,Jp Pyridinderivat mit antiulzeroeser wirkung
CA2003283A1 (en) * 1988-12-05 1990-06-05 C. Anne Higley Imidazoles for the treatment of atherosclerosis
WO1992007825A1 (fr) * 1990-11-05 1992-05-14 Taisho Pharmaceutical Co., Ltd. Derive de phenol
RU2036057C1 (ru) * 1991-01-25 1995-05-27 Александр Петрович Войнов Устройство для плющения зубьев пил
US5721266A (en) * 1993-05-28 1998-02-24 Warner-Lambert Company Substituted imidazolinyl-imidazolines as antagonists of SH-2 binding and therapeutic uses thereof
US5596001A (en) * 1993-10-25 1997-01-21 Pfizer Inc. 4-aryl-3-(heteroarylureido)quinoline derivatves
JP4191269B2 (ja) * 1996-05-17 2008-12-03 興和株式会社 新規なアニリド化合物及びこれを含有する医薬
ATE297900T1 (de) * 1997-03-25 2005-07-15 Kowa Co Anilidverbindungen und medikamente, die diese enthalten
EP0979823B1 (en) * 1997-11-14 2006-03-29 Kowa Company Ltd. Novel amide compounds and drugs containing the same

Also Published As

Publication number Publication date
HUP0002294A2 (hu) 2001-09-28
ATE285402T1 (de) 2005-01-15
NO315045B1 (no) 2003-06-30
ID23377A (id) 2000-04-20
NO995783D0 (no) 1999-11-25
EP0987254A1 (en) 2000-03-22
AU728151B2 (en) 2001-01-04
CZ415999A3 (cs) 2000-05-17
CN1258283A (zh) 2000-06-28
CA2290744A1 (en) 1998-12-03
DE69828276D1 (de) 2005-01-27
KR20010012926A (ko) 2001-02-26
CN1118457C (zh) 2003-08-20
ES2235328T3 (es) 2005-07-01
CZ297451B6 (cs) 2006-12-13
SK158299A3 (en) 2001-02-12
TW589308B (en) 2004-06-01
WO1998054153A1 (en) 1998-12-03
PT987254E (pt) 2005-04-29
JP3614865B2 (ja) 2005-01-26
HUP0002294A3 (en) 2001-10-29
AU7451298A (en) 1998-12-30
RU2207341C2 (ru) 2003-06-27
DE69828276T2 (de) 2005-12-15
CA2290744C (en) 2009-12-22
SK284891B6 (sk) 2006-02-02
NZ501156A (en) 2002-02-01
EP0987254B1 (en) 2004-12-22
EP0987254A4 (en) 2000-09-13
KR100549804B1 (ko) 2006-02-08

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