ATE257826T1 - Benzimidazolderivate und sie enthaltende medikamente - Google Patents
Benzimidazolderivate und sie enthaltende medikamenteInfo
- Publication number
- ATE257826T1 ATE257826T1 AT00939171T AT00939171T ATE257826T1 AT E257826 T1 ATE257826 T1 AT E257826T1 AT 00939171 T AT00939171 T AT 00939171T AT 00939171 T AT00939171 T AT 00939171T AT E257826 T1 ATE257826 T1 AT E257826T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- represented
- hydrogen atom
- benzimidazole derivatives
- alkyl group
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- -1 benzimidazole compound Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18114299 | 1999-06-28 | ||
| PCT/JP2000/004203 WO2001000588A1 (en) | 1999-06-28 | 2000-06-27 | Benzimidazole compounds and drugs containing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE257826T1 true ATE257826T1 (de) | 2004-01-15 |
Family
ID=16095633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00939171T ATE257826T1 (de) | 1999-06-28 | 2000-06-27 | Benzimidazolderivate und sie enthaltende medikamente |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6815455B1 (de) |
| EP (1) | EP1197487B1 (de) |
| JP (1) | JP4717305B2 (de) |
| KR (1) | KR20020022728A (de) |
| AT (1) | ATE257826T1 (de) |
| AU (1) | AU775834B2 (de) |
| CA (1) | CA2377226C (de) |
| DE (1) | DE60007748T2 (de) |
| WO (1) | WO2001000588A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060165605A1 (en) | 2001-12-28 | 2006-07-27 | Ye-Mon Chen | Process to regenerate fcc spent catalyst |
| DE102005017605B4 (de) * | 2005-04-16 | 2007-03-15 | Sanofi-Aventis Deutschland Gmbh | Substituierte 2-Aminoalkylthio-benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| CA3133732A1 (en) * | 2019-04-26 | 2020-10-29 | Generos Biopharma Ltd. | Use of compounds in the preparation of a medicament for treating atherosclerosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1226100B (it) * | 1988-07-07 | 1990-12-10 | Dompe Farmaceutici Spa | Derivati benzimidazolici farmacologicamente attivi. |
| US5387600A (en) | 1992-07-30 | 1995-02-07 | Fuji Photo Film Co., Ltd. | Treating arteriosclerosis using benzimidazole compositions |
| DE69528843T2 (de) | 1994-06-10 | 2003-09-18 | Naucno-Issledovatel'skij Institut Farmakologii Akademii Medicinskich Nauk Sssr, Moskau/Moskva | Pharmakologisch aktive 2-mercaptobenzimidazolderivate |
| WO1997003970A1 (fr) | 1995-07-17 | 1997-02-06 | Fuji Photo Film Co., Ltd. | Composes de benzimidazole |
| KR100549804B1 (ko) * | 1997-05-26 | 2006-02-08 | 코와 가부시키가이샤 | 신규한 사이클릭 디아민 화합물 및 그것을 포함하는 의약 |
| ES2262248T3 (es) | 1997-11-14 | 2006-11-16 | Kowa Company. Ltd. | Nuevos compuestos amida y medicamente que los contienen. |
| US6593323B1 (en) | 1999-06-30 | 2003-07-15 | Fuji Photo Film Co., Ltd. | Benzimidazole compounds and drugs containing the same |
-
2000
- 2000-06-27 AU AU54304/00A patent/AU775834B2/en not_active Ceased
- 2000-06-27 AT AT00939171T patent/ATE257826T1/de not_active IP Right Cessation
- 2000-06-27 DE DE60007748T patent/DE60007748T2/de not_active Expired - Lifetime
- 2000-06-27 US US10/019,249 patent/US6815455B1/en not_active Expired - Fee Related
- 2000-06-27 CA CA002377226A patent/CA2377226C/en not_active Expired - Fee Related
- 2000-06-27 WO PCT/JP2000/004203 patent/WO2001000588A1/ja not_active Ceased
- 2000-06-27 JP JP2001506998A patent/JP4717305B2/ja not_active Expired - Fee Related
- 2000-06-27 EP EP00939171A patent/EP1197487B1/de not_active Expired - Lifetime
- 2000-06-27 KR KR1020017016737A patent/KR20020022728A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU775834B2 (en) | 2004-08-19 |
| EP1197487A1 (de) | 2002-04-17 |
| EP1197487A4 (de) | 2002-10-23 |
| JP4717305B2 (ja) | 2011-07-06 |
| CA2377226C (en) | 2009-01-27 |
| WO2001000588A1 (en) | 2001-01-04 |
| EP1197487B1 (de) | 2004-01-14 |
| CA2377226A1 (en) | 2001-01-04 |
| KR20020022728A (ko) | 2002-03-27 |
| US6815455B1 (en) | 2004-11-09 |
| WO2001000588A8 (en) | 2001-03-08 |
| DE60007748D1 (de) | 2004-02-19 |
| DE60007748T2 (de) | 2004-11-25 |
| AU5430400A (en) | 2001-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |