ATE257826T1 - Benzimidazolderivate und sie enthaltende medikamente - Google Patents

Benzimidazolderivate und sie enthaltende medikamente

Info

Publication number: ATE257826T1
Authority: AT; Austria
Prior art keywords: group; represented; hydrogen atom; benzimidazole derivatives; alkyl group
Prior art date: 1999-06-28

Application number

AT00939171T

Other languages

English (en)

Inventor

Kozo Aoki

Kazuhiro Aikawa

Masayuki Kawakami

Yongzhe Yan

Original Assignee

Fuji Photo Film Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-28

Filing date

2000-06-27

Publication date

2004-01-15

2000-06-27 Application filed by Fuji Photo Film Co Ltd filed Critical Fuji Photo Film Co Ltd

2004-01-15 Application granted granted Critical

2004-01-15 Publication of ATE257826T1 publication Critical patent/ATE257826T1/de

Links

239000003814 drug Substances 0.000 title abstract 2
229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
150000001556 benzimidazoles Chemical class 0.000 title 1
229940079593 drug Drugs 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 2
206010003210 Arteriosclerosis Diseases 0.000 abstract 1
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
-1 benzimidazole compound Chemical class 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000000524 functional group Chemical group 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000005647 linker group Chemical group 0.000 abstract 1
210000002540 macrophage Anatomy 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
230000003449 preventive effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Obesity (AREA)
Diabetes (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT00939171T 1999-06-28 2000-06-27 Benzimidazolderivate und sie enthaltende medikamente ATE257826T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP18114299		1999-06-28
PCT/JP2000/004203 WO2001000588A1 (en)	1999-06-28	2000-06-27	Benzimidazole compounds and drugs containing the same

Publications (1)

Publication Number	Publication Date
ATE257826T1 true ATE257826T1 (de)	2004-01-15

Family

ID=16095633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00939171T ATE257826T1 (de)	1999-06-28	2000-06-27	Benzimidazolderivate und sie enthaltende medikamente

Country Status (9)

Country	Link
US (1)	US6815455B1 (de)
EP (1)	EP1197487B1 (de)
JP (1)	JP4717305B2 (de)
KR (1)	KR20020022728A (de)
AT (1)	ATE257826T1 (de)
AU (1)	AU775834B2 (de)
CA (1)	CA2377226C (de)
DE (1)	DE60007748T2 (de)
WO (1)	WO2001000588A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060165605A1 (en)	2001-12-28	2006-07-27	Ye-Mon Chen	Process to regenerate fcc spent catalyst
DE102005017605B4 (de) *	2005-04-16	2007-03-15	Sanofi-Aventis Deutschland Gmbh	Substituierte 2-Aminoalkylthio-benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CA3133732A1 (en) *	2019-04-26	2020-10-29	Generos Biopharma Ltd.	Use of compounds in the preparation of a medicament for treating atherosclerosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1226100B (it) *	1988-07-07	1990-12-10	Dompe Farmaceutici Spa	Derivati benzimidazolici farmacologicamente attivi.
US5387600A (en)	1992-07-30	1995-02-07	Fuji Photo Film Co., Ltd.	Treating arteriosclerosis using benzimidazole compositions
US6376666B1 (en)	1994-06-10	2002-04-23	Nauchno-Issledovatelsky Institut Farmakologii Rossiiskoi Akademii Meditsinskikh Nauk	2-mercaptobenzimidazole derivatives possessing pharmacological activity
US5998456A (en)	1995-07-17	1999-12-07	Fuji Photo Film Co., Ltd.	Benzimidazole compounds containing 1,2,4-triazole ring, and compositions and methods of use containing the same
WO1998054153A1 (en) *	1997-05-26	1998-12-03	Kowa Company, Ltd.	Novel cyclic diamine compounds and medicine containing the same
EP0979823B1 (de)	1997-11-14	2006-03-29	Kowa Company Ltd.	Neue amidverbindungen und medikamente die diese enthalten
EP1201664B1 (de)	1999-06-30	2004-09-08	Fuji Photo Film Co., Ltd.	Bemzimidazolverbindungen und medikamente die diese enthalten

2000
- 2000-06-27 AT AT00939171T patent/ATE257826T1/de not_active IP Right Cessation
- 2000-06-27 EP EP00939171A patent/EP1197487B1/de not_active Expired - Lifetime
- 2000-06-27 CA CA002377226A patent/CA2377226C/en not_active Expired - Fee Related
- 2000-06-27 KR KR1020017016737A patent/KR20020022728A/ko not_active Ceased
- 2000-06-27 WO PCT/JP2000/004203 patent/WO2001000588A1/ja not_active Ceased
- 2000-06-27 DE DE60007748T patent/DE60007748T2/de not_active Expired - Lifetime
- 2000-06-27 JP JP2001506998A patent/JP4717305B2/ja not_active Expired - Fee Related
- 2000-06-27 US US10/019,249 patent/US6815455B1/en not_active Expired - Fee Related
- 2000-06-27 AU AU54304/00A patent/AU775834B2/en not_active Ceased

Also Published As

Publication number	Publication date
DE60007748D1 (de)	2004-02-19
CA2377226A1 (en)	2001-01-04
WO2001000588A1 (en)	2001-01-04
KR20020022728A (ko)	2002-03-27
DE60007748T2 (de)	2004-11-25
US6815455B1 (en)	2004-11-09
AU5430400A (en)	2001-01-31
WO2001000588A8 (en)	2001-03-08
JP4717305B2 (ja)	2011-07-06
AU775834B2 (en)	2004-08-19
EP1197487A1 (de)	2002-04-17
CA2377226C (en)	2009-01-27
EP1197487B1 (de)	2004-01-14
EP1197487A4 (de)	2002-10-23

Legal Events

Date	Code	Title	Description
2004-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
MXPA06001274A (es)	2006-04-11	Compuestos novedosos que poseen actividad inhibitoria contra transporador dependiente de sodio.
ES2147836T3 (es)	2000-10-01	Derivados de 4,5-diariloxazol.
DE69418704D1 (de)	1999-07-01	Anthranilsäure derivate
ATE448226T1 (de)	2009-11-15	Aza heterocyclische derivate und ihre therapeutische verwendung
DK1029853T3 (da)	2004-05-24	Heteroaromatiske bicykliske derivativer, der er egnede som anticancermidler
HUT68856A (en)	1995-08-28	Acridine derivatives, pharmaceutical compositions comprising the same compouds as effective substances and a process for producing the compounds and the pharmaceutical compositions
ATE358484T1 (de)	2007-04-15	Antidiabetische medikamente
DE69122941D1 (de)	1996-12-05	Piperazinderivate
EP0640601A4 (de)	1994-03-07	Benzamid-derivate.
ATE374750T1 (de)	2007-10-15	Serotoninwiederaufnahme-inhibitoren
ATE223411T1 (de)	2002-09-15	1-methylcarbapenem-derivate
DE60007748D1 (de)	2004-02-19	Benzimidazolderivate und sie enthaltende medikamente
EP1201664A4 (de)	2002-12-18	Bemzimidazolverbindungen und medikamente die diese enthalten
DE69315363D1 (de)	1998-01-08	Amphotere tricyclische Verbindungen als antihistaminische und antiallergische Mittel
DE60009301D1 (en)	2004-04-29	Benzimidazolverbindungen
DE69624459D1 (de)	2002-11-28	Kondensierte indan-derivate und ihre salze
EP1197211A4 (de)	2004-09-01	Wirkstoffe zur vorbeugung und behandlung von krebs
EP0982029A4 (de)	2002-07-03	Vorbeugende /heilmittel fuer arteriosklerose
HU9602534D0 (en)	1996-11-28	Use of biphenyl methyl imidazole derivatives for producing pharmaceutical compositions having ocular tension derpessant activity
EP1433480A4 (de)	2005-10-05	Pyrimidinderivate enthaltendes medikament
EP1589023A4 (de)	2008-12-10	Oligosaccharidderivat
TW200508211A (en)	2005-03-01	2-naphthylimino-1,3-thiazine derivatives
FR2781155B1 (fr)	2001-10-26	Medicaments contenant des derives de polyhydroxyalkylpyrazine, les nouveaux derives de polyhydroxyalkylpyrazine et leur preparation
RU2000114184A (ru)	2004-02-20	Ацилированные гетероциклические производные, лекарственное средство, обладающее селективной антагонистической активностью против NK2-рецепторов, способ профилактики или лечения заболевания