NZ193445A - 4-amino-2-oxo-1,2-dihydro-1,8naphthyridin-3-yl carboxylic acid derivatives and precursors - Google Patents

4-amino-2-oxo-1,2-dihydro-1,8naphthyridin-3-yl carboxylic acid derivatives and precursors

Info

Publication number
NZ193445A
NZ193445A NZ193445A NZ19344580A NZ193445A NZ 193445 A NZ193445 A NZ 193445A NZ 193445 A NZ193445 A NZ 193445A NZ 19344580 A NZ19344580 A NZ 19344580A NZ 193445 A NZ193445 A NZ 193445A
Authority
NZ
New Zealand
Prior art keywords
dihydro
precursors
oxo
amino
carboxylic acid
Prior art date
Application number
NZ193445A
Other languages
English (en)
Inventor
A Santilli
A Scotese
Original Assignee
Merican Home Product Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merican Home Product Corp filed Critical Merican Home Product Corp
Publication of NZ193445A publication Critical patent/NZ193445A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ193445A 1979-04-18 1980-04-15 4-amino-2-oxo-1,2-dihydro-1,8naphthyridin-3-yl carboxylic acid derivatives and precursors NZ193445A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3125579A 1979-04-18 1979-04-18
US06/125,600 US4324893A (en) 1979-04-18 1980-02-28 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives

Publications (1)

Publication Number Publication Date
NZ193445A true NZ193445A (en) 1982-09-07

Family

ID=26707004

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ193445A NZ193445A (en) 1979-04-18 1980-04-15 4-amino-2-oxo-1,2-dihydro-1,8naphthyridin-3-yl carboxylic acid derivatives and precursors

Country Status (22)

Country Link
US (1) US4324893A (2)
EP (2) EP0060012B1 (2)
JP (1) JPS56500373A (2)
KR (1) KR840000076B1 (2)
AR (2) AR225437A1 (2)
AU (1) AU531348B2 (2)
CA (1) CA1115272A (2)
DK (1) DK537780A (2)
ES (1) ES490645A0 (2)
FI (1) FI801229A7 (2)
GB (1) GB2053198B (2)
GR (1) GR67253B (2)
HU (1) HU183125B (2)
IE (1) IE49696B1 (2)
IL (1) IL59667A (2)
IN (1) IN150969B (2)
NZ (1) NZ193445A (2)
PH (1) PH16524A (2)
PT (1) PT71081A (2)
SU (1) SU1131469A3 (2)
WO (1) WO1980002287A1 (2)
YU (1) YU105680A (2)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420615A (en) * 1981-08-24 1983-12-13 Merck & Co., Inc. Substituted pyridopyrimidines as gastric secretion inhibitors
FR2567520B1 (fr) * 1984-07-11 1987-01-02 Carpibem Nouvelles phenyl-naphthyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres
FR2592651B1 (fr) * 1986-01-06 1988-05-13 Carpibem Nouvelles phenyl naphtyridines comportant un substituant methyle en position 3, et les medicaments qui en contiennent.
NZ218773A (en) * 1986-01-06 1990-05-28 Carpibem 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions
FR2592652B1 (fr) * 1986-01-06 1988-04-29 Carpibem Nouvelles phenyl-naphtyridines, leur procede de preparation et les medicaments en contenant.
FR2592649B1 (fr) * 1986-01-06 1988-04-29 Carpibem Cyano et amido phenyl-naphtyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres.
FR2592650B1 (fr) * 1986-01-06 1988-04-29 Carpibem Nouvelles phenyl-naphtyridines fonctionnalisees en position-3, leur procede de preparation, medicaments les contenant, notamment anti-ulceres.
NZ218774A (en) * 1986-01-06 1990-06-26 Carpibem 3-substituted phenylnaphthyridines and pharmaceutical compositions
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
EP0267691A3 (en) * 1986-10-15 1989-08-23 Schering Corporation Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity.
US4916131A (en) * 1986-10-15 1990-04-10 Schering Corporation Naphthyridine derivatives and method for treating allergic reactions
FR2632861B1 (fr) * 1988-06-15 1990-11-09 Sanofi Sa Derives d'amino-4 carboxy-3 quinoleines et naphtyridines, leur procede de preparation et leur application comme medicaments
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632639B1 (fr) * 1988-06-09 1990-10-05 Sanofi Sa Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent
FR2637890B1 (fr) * 1988-09-14 1991-02-01 Europ Propulsion Materiau composite a matrice zircone
GB9318931D0 (en) * 1993-09-14 1993-10-27 Boots Co Plc Therapeutic agents
GB9420168D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
AR029185A1 (es) 1999-10-25 2003-06-18 Yamanouchi Pharma Co Ltd Derivado de naftiridina
MY140679A (en) 2001-05-24 2010-01-15 Avanir Pharmaceuticals Inhibitors of macrohage migration inhibitory factor and methods for identifying the same
KR20020092756A (ko) * 2001-06-05 2002-12-12 이종완 젓갈과 그 제조 방법
TW200418829A (en) 2003-02-14 2004-10-01 Avanir Pharmaceutics Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
EP1610795A4 (en) * 2003-04-07 2007-10-24 Cylene Pharmaceuticals Inc HETEROCYCLIC SUBSTITUTED 1,4-DIHYDRO-4-OXO-1,8-NAPHTHPYRIDINE ANALOGUE
EP1656376A1 (en) * 2003-08-22 2006-05-17 Avanir Pharmaceuticals Substituted naphthyridine derivatives as inhibitors of macrophage migration inhibitory factor and their use in the treatment of human diseases
EP1861407A1 (en) 2005-03-24 2007-12-05 Avanir Pharmaceuticals Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors
GB0605689D0 (en) * 2006-03-21 2006-05-03 Novartis Ag Organic compounds
WO2019062733A1 (zh) 2017-09-28 2019-04-04 南京药捷安康生物科技有限公司 Pde9 抑制剂及其用途
PT3814347T (pt) 2018-06-27 2023-07-18 Bristol Myers Squibb Co Compostos de naftiridinona úteis como ativadores de células t
CN112654621B (zh) 2018-06-27 2024-05-14 百时美施贵宝公司 可作为t细胞活化剂的经取代萘啶酮化合物
AR119821A1 (es) 2019-08-28 2022-01-12 Bristol Myers Squibb Co Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
CN114846007B (zh) 2019-12-23 2024-11-22 百时美施贵宝公司 可用作t细胞激活剂的经取代的喹唑啉基化合物
AR120823A1 (es) 2019-12-23 2022-03-23 Bristol Myers Squibb Co Compuestos bicíclicos sustituidos útiles como activadores de células t
EP4081522A1 (en) 2019-12-23 2022-11-02 Bristol-Myers Squibb Company Substituted piperazine derivatives useful as t cell activators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA947301A (en) * 1970-01-28 1974-05-14 Sumitomo Chemical Company Process for the preparation of compound having antibacterial action
CA988522A (en) * 1972-05-05 1976-05-04 Haydn W.R. Williams 1,8-naphthyridine compounds
US3993656A (en) * 1974-11-19 1976-11-23 Merck & Co., Inc. 1,8-Naphthyridine compounds
US4103257A (en) * 1976-05-25 1978-07-25 The United States Of America As Represented By The United States Department Of Energy Azaquinolone dye lasers
US4133885A (en) * 1977-07-18 1979-01-09 Merck & Co., Inc. Substituted naphthyridinones

Also Published As

Publication number Publication date
PT71081A (en) 1980-05-01
SU1131469A3 (ru) 1984-12-23
EP0018735B1 (en) 1983-07-27
ES8104286A1 (es) 1981-04-16
GB2053198B (en) 1983-04-07
FI801229A7 (fi) 1981-01-01
KR830002759A (ko) 1983-05-30
GR67253B (2) 1981-06-26
AR227427A1 (es) 1982-10-29
EP0060012B1 (en) 1984-08-29
IE49696B1 (en) 1985-11-27
IL59667A (en) 1983-11-30
KR840000076B1 (ko) 1984-02-08
US4324893A (en) 1982-04-13
HU183125B (en) 1984-04-28
AR225437A1 (es) 1982-03-31
IE800761L (en) 1980-10-18
YU105680A (en) 1983-09-30
DK537780A (da) 1980-12-17
JPS56500373A (2) 1981-03-26
GB2053198A (en) 1981-02-04
AU5751980A (en) 1980-10-23
IN150969B (2) 1983-02-05
PH16524A (en) 1983-11-10
AU531348B2 (en) 1983-08-18
CA1115272A (en) 1981-12-29
WO1980002287A1 (en) 1980-10-30
ES490645A0 (es) 1981-04-16
EP0018735A1 (en) 1980-11-12
EP0060012A1 (en) 1982-09-15

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