NZ228108A - Bacillus thuringiensis delta-endotoxin variants and insecticidal compositions - Google Patents

Bacillus thuringiensis delta-endotoxin variants and insecticidal compositions

Info

Publication number: NZ228108A
Authority: NZ; New Zealand
Prior art keywords: amino acid; dna; prak; sequence; coded
Prior art date: 1988-02-25

Application number

NZ228108A

Other languages

English (en)

Inventor

Cindy Lou Jellis

James Robert Rusche

Daniel Parker Witt

Original Assignee

Sandoz Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-25

Filing date

1989-02-23

Publication date

1992-04-28

1989-02-23 Application filed by Sandoz Ltd filed Critical Sandoz Ltd

1992-04-28 Publication of NZ228108A publication Critical patent/NZ228108A/en

Links

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GJNDXQBALKCYSZ-RYUDHWBXSA-N Val-Phe Chemical compound CC(C)[C@H]([NH3+])C(=O)N[C@H](C([O-])=O)CC1=CC=CC=C1 GJNDXQBALKCYSZ-RYUDHWBXSA-N 0.000 description 1
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AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
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239000013078 crystal Substances 0.000 description 1
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RGWHQCVHVJXOKC-SHYZEUOFSA-J dCTP(4-) Chemical compound O=C1N=C(N)C=CN1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)C1 RGWHQCVHVJXOKC-SHYZEUOFSA-J 0.000 description 1
HAAZLUGHYHWQIW-KVQBGUIXSA-N dGTP Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 HAAZLUGHYHWQIW-KVQBGUIXSA-N 0.000 description 1
NHVNXKFIZYSCEB-XLPZGREQSA-N dTTP Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)C1 NHVNXKFIZYSCEB-XLPZGREQSA-N 0.000 description 1
230000018044 dehydration Effects 0.000 description 1
238000006297 dehydration reaction Methods 0.000 description 1
238000000502 dialysis Methods 0.000 description 1
229940079593 drug Drugs 0.000 description 1
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238000001035 drying Methods 0.000 description 1
238000001962 electrophoresis Methods 0.000 description 1
238000004520 electroporation Methods 0.000 description 1
230000002346 endotoxic effect Effects 0.000 description 1
230000007893 endotoxin activity Effects 0.000 description 1
238000001976 enzyme digestion Methods 0.000 description 1
BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 1
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230000007160 gastrointestinal dysfunction Effects 0.000 description 1
108010055341 glutamyl-glutamic acid Proteins 0.000 description 1
108010049041 glutamylalanine Proteins 0.000 description 1
VPZXBVLAVMBEQI-UHFFFAOYSA-N glycyl-DL-alpha-alanine Natural products OC(=O)C(C)NC(=O)CN VPZXBVLAVMBEQI-UHFFFAOYSA-N 0.000 description 1
108010045126 glycyl-tyrosyl-glycine Proteins 0.000 description 1
108010084760 glycyl-tyrosyl-glycyl-aspartate Proteins 0.000 description 1
108010084389 glycyltryptophan Proteins 0.000 description 1
108010087823 glycyltyrosine Proteins 0.000 description 1
231100000001 growth retardation Toxicity 0.000 description 1
238000003306 harvesting Methods 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
238000003119 immunoblot Methods 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
238000003780 insertion Methods 0.000 description 1
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238000011835 investigation Methods 0.000 description 1
108010044311 leucyl-glycyl-glycine Proteins 0.000 description 1
108010000761 leucylarginine Proteins 0.000 description 1
108010091798 leucylleucine Proteins 0.000 description 1
108010012058 leucyltyrosine Proteins 0.000 description 1
238000009630 liquid culture Methods 0.000 description 1
238000012423 maintenance Methods 0.000 description 1
238000013507 mapping Methods 0.000 description 1
230000021121 meiosis Effects 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
244000005700 microbiome Species 0.000 description 1
238000000520 microinjection Methods 0.000 description 1
230000003278 mimic effect Effects 0.000 description 1
230000011278 mitosis Effects 0.000 description 1
238000010369 molecular cloning Methods 0.000 description 1
231100000219 mutagenic Toxicity 0.000 description 1
230000003505 mutagenic effect Effects 0.000 description 1
RZSCFTDHFNHMOR-UHFFFAOYSA-N n-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide;1,1-dimethyl-3-(4-propan-2-ylphenyl)urea Chemical compound CC(C)C1=CC=C(NC(=O)N(C)C)C=C1.FC1=CC(F)=CC=C1NC(=O)C1=CC=CN=C1OC1=CC=CC(C(F)(F)F)=C1 RZSCFTDHFNHMOR-UHFFFAOYSA-N 0.000 description 1
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125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
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231100000654 protein toxin Toxicity 0.000 description 1
230000006337 proteolytic cleavage Effects 0.000 description 1
LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 1
235000019171 pyridoxine hydrochloride Nutrition 0.000 description 1
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238000011069 regeneration method Methods 0.000 description 1
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229960002477 riboflavin Drugs 0.000 description 1
235000019192 riboflavin Nutrition 0.000 description 1
239000002151 riboflavin Substances 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
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235000010199 sorbic acid Nutrition 0.000 description 1
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238000009987 spinning Methods 0.000 description 1
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239000006228 supernatant Substances 0.000 description 1
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DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Agronomy & Crop Science (AREA)
Virology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Pest Control & Pesticides (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Dentistry (AREA)
Wood Science & Technology (AREA)
Environmental Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

NZ228108A 1988-02-25 1989-02-23 Bacillus thuringiensis delta-endotoxin variants and insecticidal compositions NZ228108A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US16023388A	1988-02-25	1988-02-25

Publications (1)

Publication Number	Publication Date
NZ228108A true NZ228108A (en)	1992-04-28

Family

ID=22576065

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ228108A NZ228108A (en)	1988-02-25	1989-02-23	Bacillus thuringiensis delta-endotoxin variants and insecticidal compositions

Country Status (23)

Country	Link
JP (1)	JPH025872A (da)
CN (1)	CN1037538A (da)
AT (1)	AT396940B (da)
AU (1)	AU616945B2 (da)
BE (1)	BE1001877A4 (da)
BR (1)	BR8900881A (da)
DE (1)	DE3905865A1 (da)
DK (1)	DK84589A (da)
ES (1)	ES2012283A6 (da)
FR (1)	FR2627778B1 (da)
GB (1)	GB2216127B (da)
GR (1)	GR1000457B (da)
HU (1)	HU209148B (da)
IE (1)	IE62118B1 (da)
IL (1)	IL89391A (da)
IT (1)	IT1230483B (da)
MY (1)	MY104405A (da)
NL (1)	NL8900481A (da)
NZ (1)	NZ228108A (da)
PL (1)	PL161726B1 (da)
PT (1)	PT89812B (da)
TR (1)	TR26073A (da)
ZA (1)	ZA891463B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8910624D0 (en) *	1989-05-09	1989-06-21	Ici Plc	Bacterial strains
CA2032405A1 (en) *	1989-12-18	1991-06-19	Cindy L. Jellis	Organic compounds
GB9408466D0 (en) *	1994-04-27	1994-06-22	Univ Nottingham	Cloning and functional expression of neurotoxins
EP0861021B1 (en) *	1995-10-13	2009-09-23	Dow Agrosciences LLC	Modified bacillus thuringiensis gene for lepidopteran control in plants
US6474576B1 (en)	1999-03-10	2002-11-05	Sumitomo Special Metals Co., Ltd.	Milling apparatus and milling method
JP4855772B2 (ja) *	2005-12-21	2012-01-18	ノリタケ伊勢電子株式会社	蛍光表示装置
JP4753987B2 (ja)	2008-11-10	2011-08-24	双葉電子工業株式会社	蛍光表示管及び駆動方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2540484B2 (ja) *	1984-12-12	1996-10-02	サントリー株式会社	殺虫性蛋白質をコ−ドする遺伝子
EP0206613B1 (en) *	1985-06-14	1992-08-19	Repligen Corporation	Activated bacillus thuringienses delta-endotoxin produced by an engineered hybrid gene
CA1341092C (en) *	1985-12-12	2000-09-05	David L. Edwards	Process for altering the host range of bacillus thuringiensis toxins, and novel toxins produced thereby
DE3855827T2 (de) *	1987-04-16	1997-11-27	Ecogen Inc	Bacillus thuringiensis p-2-toxingen, protein und damit in zusammenhang stehende insektizide zusammensetzungen

1989
- 1989-01-27 BR BR898900881A patent/BR8900881A/pt not_active IP Right Cessation
- 1989-02-15 HU HU89760A patent/HU209148B/hu not_active IP Right Cessation
- 1989-02-22 IT IT8947678A patent/IT1230483B/it active
- 1989-02-22 GB GB8904016A patent/GB2216127B/en not_active Expired - Lifetime
- 1989-02-23 IL IL8939189A patent/IL89391A/en not_active IP Right Cessation
- 1989-02-23 NZ NZ228108A patent/NZ228108A/en unknown
- 1989-02-23 JP JP1044989A patent/JPH025872A/ja active Pending
- 1989-02-23 PT PT89812A patent/PT89812B/pt not_active IP Right Cessation
- 1989-02-23 GR GR890100115A patent/GR1000457B/el unknown
- 1989-02-23 AU AU30297/89A patent/AU616945B2/en not_active Ceased
- 1989-02-23 DK DK084589A patent/DK84589A/da not_active Application Discontinuation
- 1989-02-24 CN CN89101863A patent/CN1037538A/zh active Pending
- 1989-02-24 MY MYPI89000227A patent/MY104405A/en unknown
- 1989-02-24 DE DE3905865A patent/DE3905865A1/de not_active Withdrawn
- 1989-02-24 AT AT0041389A patent/AT396940B/de not_active IP Right Cessation
- 1989-02-24 IE IE58989A patent/IE62118B1/en not_active IP Right Cessation
- 1989-02-24 FR FR8902428A patent/FR2627778B1/fr not_active Expired - Lifetime
- 1989-02-24 ZA ZA891463A patent/ZA891463B/xx unknown
- 1989-02-24 TR TR89/0166A patent/TR26073A/xx unknown
- 1989-02-24 BE BE8900189A patent/BE1001877A4/fr not_active IP Right Cessation
- 1989-02-24 ES ES8900683A patent/ES2012283A6/es not_active Expired - Lifetime
- 1989-02-24 PL PL89277925A patent/PL161726B1/pl unknown
- 1989-02-27 NL NL8900481A patent/NL8900481A/nl not_active Application Discontinuation

Also Published As

Publication number	Publication date
IE62118B1 (en)	1994-12-14
JPH025872A (ja)	1990-01-10
ZA891463B (en)	1990-10-31
IT1230483B (it)	1991-10-24
GB8904016D0 (en)	1989-04-05
GB2216127A (en)	1989-10-04
IE890589L (en)	1989-08-25
TR26073A (tr)	1993-12-16
IL89391A (en)	1995-01-24
HU209148B (en)	1994-03-28
BE1001877A4 (fr)	1990-04-03
FR2627778B1 (fr)	1990-09-21
GR1000457B (el)	1992-07-30
GB2216127B (en)	1991-11-06
NL8900481A (nl)	1989-09-18
PT89812B (pt)	1994-04-29
PL277925A1 (en)	1990-02-05
ATA41389A (de)	1993-05-15
PL161726B1 (pl)	1993-07-30
IL89391A0 (en)	1989-09-10
DK84589A (da)	1989-08-26
IT8947678A0 (it)	1989-02-22
MY104405A (en)	1994-03-31
AU616945B2 (en)	1991-11-14
AT396940B (de)	1993-12-27
PT89812A (pt)	1989-10-04
CN1037538A (zh)	1989-11-29
BR8900881A (pt)	1989-10-17
HUT50507A (en)	1990-02-28
DE3905865A1 (de)	1989-09-07
DK84589D0 (da)	1989-02-23
AU3029789A (en)	1989-10-12
ES2012283A6 (es)	1990-03-01
FR2627778A1 (fr)	1989-09-01

Publication	Publication Date	Title
De Lorimier et al.	1984	Genes for the alpha and beta subunits of phycocyanin.
US5338544A (en)	1994-08-16	CryIIB protein, insecticidal compositions and methods of use thereof
US6140104A (en)	2000-10-31	Nucleotide sequences for the control of the expression of DNA sequences in a cell host
Hani et al.	1995	Expression and characterization of Campylobacter jejuni benzoylglycine amidohydrolase (hippuricase) gene in Escherichia coli
AU643511B2 (en)	1993-11-18	Bacterial vectors
Grewal et al.	1995	Identification and characterization of a locus which regulates multiple functions in Pseudomonas tolaasii, the cause of brown blotch disease of Agaricus bisporus
JPH05505109A (ja)	1993-08-05	バチルス・スリンギエンシスのｃｒｙＩＩＩＣ遺伝子および蛸翅目の昆虫に対して毒性のタンパク質
Aronson et al.	1989	Gene structure and precursor processing of a novel Bacillus subtilis spore coat protein
Hindley et al.	1987	Identification, cloning and sequence analysis of the Bacillus sphaericus 1593 41.9 kD larvicidal toxin gene
CA2117270A1 (en)	1994-03-03	Use of bacillus thuringiensis isolates for controlling pests in the family aphididae
NZ334847A (en)	2001-03-30	Oral insecticidal composition containing protein fragments derived from a Xenorhabdus species
NZ228108A (en)	1992-04-28	Bacillus thuringiensis delta-endotoxin variants and insecticidal compositions
US5073632A (en)	1991-12-17	CryIIB crystal protein gene from Bacillus thuringiensis
US6942991B2 (en)	2005-09-13	Nucleotide sequences coding for polypeptides endowed with a larvicidal activity towards Lepidoptera
US5928897A (en)	1999-07-27	Expression of a gram-positive bacteria replicon
AU649785B2 (en)	1994-06-02	Bacillus thuringiensis cryIIIC(b) toxin gene and protein toxic to coleopteran insects
AU643800B2 (en)	1993-11-25	Shuttle vector for recombinant bacillus thuringiensis strain development
DK175525B1 (da)	2004-11-22	Fremgangsmåde til fremstilling af fusionsproteiner, genstruktur, vektor indeholdende genstrukturen, streptomycetcelle indeholdende vektoren, fusionsprotein og anvendelse deraf
US6071877A (en)	2000-06-06	Polypeptides having a toxic activity against insects of the dipterae family
IE913237A1 (en)	1992-02-25	Cloning of dna fragments encoding a mechanism for resistance¹to bacteriophages
EP0433945A2 (en)	1991-06-26	Insecticides produced by transformation of B.t. Kurstaki with heterologeous genes
CA2325831C (en)	2002-01-01	Bacillus thuringiensis cryiiic gene and protein toxic to coleopteran insects