OA07716A - Dérivés d'acides isoindoledicarboxyliques, leur préparation et compositions pharmaceutiques les contenant. - Google Patents

Dérivés d'acides isoindoledicarboxyliques, leur préparation et compositions pharmaceutiques les contenant.

Info

Publication number: OA07716A
Authority: OA; OAPI
Prior art keywords: carbon atoms; formula; alkyl radical; see diagramm; compatible mineral
Prior art date: 1983-06-06

Application number

OA58310A

Other languages

English (en)

French (fr)

Inventor

Michel Vincent

Georges Remond

Michel Laubie

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-06

Filing date

1984-06-06

Publication date

1985-08-30

1984-06-06 Application filed by Adir filed Critical Adir

1985-08-30 Publication of OA07716A publication Critical patent/OA07716A/xx

Links

238000002360 preparation method Methods 0.000 title abstract 2
DQJCYUPXDWAEPO-UHFFFAOYSA-N 2h-isoindole-1,3-dicarboxylic acid Chemical class C1=CC=CC2=C(C(=O)O)NC(C(O)=O)=C21 DQJCYUPXDWAEPO-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 7
150000003839 salts Chemical class 0.000 abstract 5
150000001875 compounds Chemical class 0.000 abstract 4
229910052500 inorganic mineral Inorganic materials 0.000 abstract 4
239000011707 mineral Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
150000007522 mineralic acids Chemical class 0.000 abstract 2
230000003287 optical effect Effects 0.000 abstract 2
150000007524 organic acids Chemical class 0.000 abstract 2
150000007530 organic bases Chemical class 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
CZTREFQQQAJNFV-UHFFFAOYSA-N 2h-isoindole-1-carboxylic acid Chemical class C1=CC=CC2=C(C(=O)O)NC=C21 CZTREFQQQAJNFV-UHFFFAOYSA-N 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
238000007127 saponification reaction Methods 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

OA58310A 1983-06-06 1984-06-06 Dérivés d'acides isoindoledicarboxyliques, leur préparation et compositions pharmaceutiques les contenant. OA07716A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8309326A FR2546886B2 (fr)	1983-06-06	1983-06-06	Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number	Publication Date
OA07716A true OA07716A (fr)	1985-08-30

Family

ID=9289500

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA58310A OA07716A (fr)	1983-06-06	1984-06-06	Dérivés d'acides isoindoledicarboxyliques, leur préparation et compositions pharmaceutiques les contenant.

Country Status (13)

Country	Link
EP (1)	EP0129461B1 (de)
JP (1)	JPS6011467A (de)
AT (1)	ATE25258T1 (de)
AU (1)	AU566490B2 (de)
CA (1)	CA1274347A (de)
DE (1)	DE3462261D1 (de)
ES (1)	ES8506623A1 (de)
FR (1)	FR2546886B2 (de)
IE (1)	IE57600B1 (de)
NZ (1)	NZ208386A (de)
OA (1)	OA07716A (de)
PT (1)	PT78697A (de)
ZA (1)	ZA844262B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986000896A1 (en) *	1984-07-30	1986-02-13	Schering Corporation	NOVEL PROCESS FOR THE PREPARATION OF CIS, ENDOOCTAHYDROCYCLOPENTA ADb BDPYRROLE-2-CARBOXYLATE
DE3640641A1 (de) *	1986-11-28	1988-07-14	Thomae Gmbh Dr K	Neue heteroaromatische aminderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US4902695A (en) *	1989-02-13	1990-02-20	Eli Lilly And Company	Excitatory amino acid receptor antagonists
EP1603558B1 (de)	2003-02-28	2008-05-21	Les Laboratoires Servier S.A.	Verfahren zur herstellung von perindopril

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2487829A2 (fr) *	1979-12-07	1982-02-05	Science Union & Cie	Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3177130D1 (de) *	1980-08-30	1990-01-11	Hoechst Ag	Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
EP0050800B2 (de) *	1980-10-23	1995-06-07	Schering Corporation	Carboxyalkyl-Dipeptide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
ZA817261B (en) *	1980-10-23	1982-09-29	Schering Corp	Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
GB2086390B (en) *	1980-11-03	1984-06-06	Ciba Geigy Ag	1-carboxy-azaalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application
JPS57158758A (en) *	1981-02-17	1982-09-30	Warner Lambert Co	Substatuted acyl derivative of octahydro-1h- isoindole-1-carboxylic acid
DE3260423D1 (en) *	1981-02-17	1984-08-30	Warner Lambert Co	Substituted acyl derivatives of octahydro-1h-isoindole-1-carboxylic acids and esters
EP0081094A1 (de) *	1981-11-12	1983-06-15	Merck & Co. Inc.	Omega-aminocarboxymethyldipeptidische antihypertensive Mittel
US4431644A (en) *	1982-03-08	1984-02-14	Schering Corporation	Antihypertensive agents
DE3211676A1 (de) *	1982-03-30	1983-10-06	Hoechst Ag	Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
DE3315464A1 (de) *	1983-04-28	1984-10-31	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern

1983
- 1983-06-06 FR FR8309326A patent/FR2546886B2/fr not_active Expired
1984
- 1984-06-05 CA CA000455843A patent/CA1274347A/fr not_active Expired - Lifetime
- 1984-06-05 AT AT84401145T patent/ATE25258T1/de not_active IP Right Cessation
- 1984-06-05 PT PT78697A patent/PT78697A/pt not_active IP Right Cessation
- 1984-06-05 EP EP84401145A patent/EP0129461B1/de not_active Expired
- 1984-06-05 IE IE1386/84A patent/IE57600B1/en not_active IP Right Cessation
- 1984-06-05 NZ NZ208386A patent/NZ208386A/xx unknown
- 1984-06-05 DE DE8484401145T patent/DE3462261D1/de not_active Expired
- 1984-06-06 ZA ZA844262A patent/ZA844262B/xx unknown
- 1984-06-06 OA OA58310A patent/OA07716A/xx unknown
- 1984-06-06 JP JP59116318A patent/JPS6011467A/ja active Pending
- 1984-06-06 AU AU29151/84A patent/AU566490B2/en not_active Ceased
- 1984-06-06 ES ES533174A patent/ES8506623A1/es not_active Expired

Also Published As

Publication number	Publication date
AU2915184A (en)	1984-12-20
EP0129461A1 (de)	1984-12-27
FR2546886B2 (fr)	1986-05-16
PT78697A (fr)	1984-07-01
FR2546886A2 (fr)	1984-12-07
CA1274347A (fr)	1990-09-18
JPS6011467A (ja)	1985-01-21
IE841386L (en)	1984-12-06
NZ208386A (en)	1989-01-27
ATE25258T1 (de)	1987-02-15
DE3462261D1 (en)	1987-03-05
AU566490B2 (en)	1987-10-22
ES533174A0 (es)	1985-08-01
ZA844262B (en)	1985-01-30
IE57600B1 (en)	1993-01-27
ES8506623A1 (es)	1985-08-01
EP0129461B1 (de)	1987-01-28

Publication	Publication Date	Title
LU90317I2 (fr)	1999-01-11	Tacrolimus et ses sels et dérivés pharmaceutiquement acceptables
EA199800394A1 (ru)	1998-10-29	Пиразолпиримидины как антагонисты крф рецепторов
PT83521A (fr)	1986-11-01	Procede de preparation de nouveaux derives bibycliques naphtaleniques et leurs compositions pharmaceutiques et cosmetiques
EP0039051A3 (en)	1982-05-26	Mannich-base hydroxamic acid prodrugs for the improved delivery of non-steroidal anti-inflammatory agents, a process for preparing and a pharmaceutical composition containing them
ES8306160A1 (es)	1983-05-01	"procedimiento para preparar un nuevo compuesto de cefem".
ES8500902A1 (es)	1984-11-01	Un procedimiento para la preparacion de un derivado del indol.
EP0293771A3 (de)	1990-10-17	Cephalosporinverbindungen und sie enthaltende pharmazeutische Präparate
EP0149487A3 (en)	1986-05-14	New cephem compounds, process for preparation thereof and pharmaceutical compositions containing them
ATE19773T1 (de)	1986-05-15	Nitroaliphatische verbindungen, verfahren zu deren herstellung und deren verwendung.
PH24176A (en)	1990-03-22	New bicyclic compounds,process for preparation thereof and pharmaceutical composition comprising the same
LV10235A (lv)	1994-10-20	Jauni esteri to iegusanas panemiens farmaceitiska kompozicija arstesanas metode
FR2546886B2 (fr)	1986-05-16	Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
DE3483881D1 (de)	1991-02-07	1,3-dioxan-4-ylalkensaeure.
ES8603406A1 (es)	1985-12-16	Un procedimiento para producir derivados de acilindol
ATE218861T1 (de)	2002-06-15	Vasculäre hypertrophicsuppressor
GB1066266A (en)	1967-04-26	Diazepine derivatives
GB889660A (en)	1962-02-21	Morphanthridine compounds
DE3063105D1 (en)	1983-06-16	Clavulanic acid derivatives, process for their preparation and pharmaceutical compositions containing them
FR2317932A2 (fr)	1977-02-11	Derives d'indolobenzazepines, leur preparation et compositions pharmaceutiques les contenant
GB1032251A (en)	1966-06-08	Piperazine compounds and their preparation
AR003109A1 (es)	1998-07-08	Compuesto con actividad antitumoral importante y toxicidad baja y sal farmaceuticamente aceptable compuesto y composicion farmaceutica que locontiene
ZA9711708B (en)	1998-06-25	Ellipticine compounds, a process for their preparation and pharmaceutical compositions containing them.
ES8600762A1 (es)	1985-02-16	Un procedimiento para la preparacion de nuevos compuestos de beta-lactama.