OA10332A - Compositions possédant des proprietés antivirales et procédé d'obtention - Google Patents

Compositions possédant des proprietés antivirales et procédé d'obtention Download PDF

Info

Publication number: OA10332A
Authority: OA; OAPI
Prior art keywords: composition according; acetic acid; filtrate; compositions; coconut
Prior art date: 1995-03-06

Application number

OA60910A

Other languages

English (en)

French (fr)

Inventor

Alix Roland Commin

Original Assignee

Alix Roland Commin

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-06

Filing date

1996-10-25

Publication date

1997-10-07

1996-10-25 Application filed by Alix Roland Commin filed Critical Alix Roland Commin

1997-10-07 Publication of OA10332A publication Critical patent/OA10332A/fr

Links

239000000203 mixture Substances 0.000 title claims abstract description 60
230000000840 anti-viral effect Effects 0.000 title claims description 5
238000000034 method Methods 0.000 title claims description 5
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 33
235000013162 Cocos nucifera Nutrition 0.000 claims abstract description 16
244000060011 Cocos nucifera Species 0.000 claims abstract description 16
239000000843 powder Substances 0.000 claims abstract description 12
239000000284 extract Substances 0.000 claims abstract description 7
229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 6
239000011707 mineral Substances 0.000 claims abstract description 6
150000003839 salts Chemical class 0.000 claims abstract description 5
241000208223 Anacardiaceae Species 0.000 claims abstract description 4
241000221017 Euphorbiaceae Species 0.000 claims abstract description 4
241000234280 Liliaceae Species 0.000 claims abstract 2
235000013399 edible fruits Nutrition 0.000 claims description 10
241000159165 Spondias Species 0.000 claims description 8
239000000706 filtrate Substances 0.000 claims description 8
235000008981 Smilax officinalis Nutrition 0.000 claims description 6
240000002493 Smilax officinalis Species 0.000 claims description 6
239000004615 ingredient Substances 0.000 claims description 6
235000004443 Ricinus communis Nutrition 0.000 claims description 5
230000000798 anti-retroviral effect Effects 0.000 claims description 5
240000001439 Opuntia Species 0.000 claims description 4
238000002803 maceration Methods 0.000 claims description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 2
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 2
229910019142 PO4 Inorganic materials 0.000 claims description 2
238000009835 boiling Methods 0.000 claims description 2
239000011575 calcium Substances 0.000 claims description 2
229910052791 calcium Inorganic materials 0.000 claims description 2
150000004649 carbonic acid derivatives Chemical class 0.000 claims description 2
239000004359 castor oil Substances 0.000 claims description 2
235000019438 castor oil Nutrition 0.000 claims description 2
150000003841 chloride salts Chemical class 0.000 claims description 2
239000003814 drug Substances 0.000 claims description 2
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 2
239000011777 magnesium Substances 0.000 claims description 2
229910052749 magnesium Inorganic materials 0.000 claims description 2
235000021317 phosphate Nutrition 0.000 claims description 2
150000003013 phosphoric acid derivatives Chemical class 0.000 claims description 2
239000013535 sea water Substances 0.000 claims description 2
239000011734 sodium Substances 0.000 claims description 2
229910052708 sodium Inorganic materials 0.000 claims description 2
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
229940124522 antiretrovirals Drugs 0.000 claims 1
239000011591 potassium Substances 0.000 claims 1
229910052700 potassium Inorganic materials 0.000 claims 1
150000003467 sulfuric acid derivatives Chemical class 0.000 claims 1
241000219357 Cactaceae Species 0.000 abstract description 2
241000700605 Viruses Species 0.000 description 23
102100034343 Integrase Human genes 0.000 description 19
108010092799 RNA-directed DNA polymerase Proteins 0.000 description 19
230000000694 effects Effects 0.000 description 15
210000004027 cell Anatomy 0.000 description 11
238000012360 testing method Methods 0.000 description 9
208000015181 infectious disease Diseases 0.000 description 8
239000000243 solution Substances 0.000 description 8
241000713772 Human immunodeficiency virus 1 Species 0.000 description 7
241000725303 Human immunodeficiency virus Species 0.000 description 6
229960000583 acetic acid Drugs 0.000 description 6
238000010790 dilution Methods 0.000 description 5
239000012895 dilution Substances 0.000 description 5
238000002474 experimental method Methods 0.000 description 5
238000004519 manufacturing process Methods 0.000 description 5
239000000725 suspension Substances 0.000 description 5
208000030507 AIDS Diseases 0.000 description 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
239000002609 medium Substances 0.000 description 4
239000002245 particle Substances 0.000 description 4
108091003079 Bovine Serum Albumin Proteins 0.000 description 3
239000012894 fetal calf serum Substances 0.000 description 3
239000001963 growth medium Substances 0.000 description 3
230000002779 inactivation Effects 0.000 description 3
230000005764 inhibitory process Effects 0.000 description 3
230000003612 virological effect Effects 0.000 description 3
239000012980 RPMI-1640 medium Substances 0.000 description 2
239000006146 Roswell Park Memorial Institute medium Substances 0.000 description 2
238000011161 development Methods 0.000 description 2
238000000338 in vitro Methods 0.000 description 2
230000002401 inhibitory effect Effects 0.000 description 2
238000005259 measurement Methods 0.000 description 2
239000008194 pharmaceutical composition Substances 0.000 description 2
238000011533 pre-incubation Methods 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
238000011160 research Methods 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
239000006228 supernatant Substances 0.000 description 2
238000011282 treatment Methods 0.000 description 2
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 2
229960002555 zidovudine Drugs 0.000 description 2
BLKPFVWYBFDTPX-UHFFFAOYSA-N 2-(6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl)acetaldehyde Chemical compound C1C2C(C)(C)C1CC=C2CC=O BLKPFVWYBFDTPX-UHFFFAOYSA-N 0.000 description 1
102000004163 DNA-directed RNA polymerases Human genes 0.000 description 1
108090000626 DNA-directed RNA polymerases Proteins 0.000 description 1
241000282412 Homo Species 0.000 description 1
241000714260 Human T-lymphotropic virus 1 Species 0.000 description 1
241000234435 Lilium Species 0.000 description 1
235000013389 Opuntia humifusa var. humifusa Nutrition 0.000 description 1
240000008607 Opuntia megacantha Species 0.000 description 1
235000002840 Opuntia megacantha Nutrition 0.000 description 1
235000006538 Opuntia tuna Nutrition 0.000 description 1
240000009164 Petroselinum crispum Species 0.000 description 1
239000012979 RPMI medium Substances 0.000 description 1
239000002253 acid Substances 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
239000003443 antiviral agent Substances 0.000 description 1
238000003556 assay Methods 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
230000003833 cell viability Effects 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
230000000120 cytopathologic effect Effects 0.000 description 1
201000010099 disease Diseases 0.000 description 1
231100000676 disease causative agent Toxicity 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
210000005260 human cell Anatomy 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
238000011534 incubation Methods 0.000 description 1
230000002458 infectious effect Effects 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007928 intraperitoneal injection Substances 0.000 description 1
VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 1
150000003833 nucleoside derivatives Chemical class 0.000 description 1
235000011197 perejil Nutrition 0.000 description 1
OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical class [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 1
239000001120 potassium sulphate Substances 0.000 description 1
235000011151 potassium sulphates Nutrition 0.000 description 1
230000002265 prevention Effects 0.000 description 1
239000000047 product Substances 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
241000894007 species Species 0.000 description 1
238000010186 staining Methods 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
238000002627 tracheal intubation Methods 0.000 description 1
241001430294 unidentified retrovirus Species 0.000 description 1
239000000052 vinegar Substances 0.000 description 1
235000021419 vinegar Nutrition 0.000 description 1
230000029812 viral genome replication Effects 0.000 description 1
-1 zidovudine Chemical class 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Natural Medicines & Medicinal Plants (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Alternative & Traditional Medicine (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Medical Informatics (AREA)
Botany (AREA)
Biotechnology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

OA60910A 1995-03-06 1996-10-25 Compositions possédant des proprietés antivirales et procédé d'obtention OA10332A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9502595A FR2731354B1 (fr)	1995-03-06	1995-03-06	Compositions possedant des proprietes antivirales et procede d'obtention

Publications (1)

Publication Number	Publication Date
OA10332A true OA10332A (fr)	1997-10-07

Family

ID=9476780

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA60910A OA10332A (fr)	1995-03-06	1996-10-25	Compositions possédant des proprietés antivirales et procédé d'obtention

Country Status (15)

Country	Link
EP (1)	EP0768887B1 (de)
JP (1)	JPH10506124A (de)
AP (1)	AP705A (de)
AT (1)	ATE201825T1 (de)
AU (1)	AU711634B2 (de)
CA (1)	CA2189474C (de)
DE (1)	DE69613190T2 (de)
DK (1)	DK0768887T3 (de)
EA (1)	EA000112B1 (de)
ES (1)	ES2171653T3 (de)
FR (1)	FR2731354B1 (de)
GR (1)	GR3036556T3 (de)
OA (1)	OA10332A (de)
PT (1)	PT768887E (de)
WO (1)	WO1996027383A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000001398A1 (en) *	1998-07-02	2000-01-13	Nobutho Gladys Makupula	Anti-viral plant extract
US6238672B1 (en)	1999-04-23	2001-05-29	E. Excel International Inc.	Dietary supplements containing dehydrated cactus fruit juice and ginseng berry juice
MY124001A (en) *	1999-04-23	2006-06-30	E Excel Int	Dietary supplements containing dehydrated cactus fruit juice and ginseng berry juice
US6524626B2 (en)	1999-04-23	2003-02-25	E Excel International, Inc.	Ginseng berry topical products
US6576286B1 (en)	1999-04-23	2003-06-10	E Excel International	Cactus fruit drinks and food products
US6210738B1 (en)	1999-04-23	2001-04-03	E Excel Internatioanal Inc.	Freeze-dried ginseng berry tea
FR2926465B1 (fr) *	2008-01-17	2016-08-12	Alix Roland Commin	Composition anti-virale notamment le sida
WO2011010000A1 (fr) *	2009-07-22	2011-01-27	Alix Roland Commin	Composition antivirale et retrovirale notamment pour le traitement du sida

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0825890B2 (ja) *	1987-06-18	1996-03-13	呉羽化学工業株式会社	抗ウイルス剤
FR2662353A1 (fr) *	1990-05-22	1991-11-29	Neyroud Andre	Savon en pain ou liquide antiseptique puissant, qui detruit les virus du sida, assure l'hygiene corporelle et protege la peau.
GB9126393D0 (en) *	1991-12-12	1992-02-12	Skinner Gordon R B	Anti microbial activity from extracts of cactus

1995
- 1995-03-06 FR FR9502595A patent/FR2731354B1/fr not_active Expired - Fee Related
1996
- 1996-02-13 DE DE69613190T patent/DE69613190T2/de not_active Expired - Fee Related
- 1996-02-13 EA EA199600087A patent/EA000112B1/ru not_active IP Right Cessation
- 1996-02-13 PT PT96904129T patent/PT768887E/pt unknown
- 1996-02-13 ES ES96904129T patent/ES2171653T3/es not_active Expired - Lifetime
- 1996-02-13 DK DK96904129T patent/DK0768887T3/da active
- 1996-02-13 AT AT96904129T patent/ATE201825T1/de not_active IP Right Cessation
- 1996-02-13 WO PCT/FR1996/000230 patent/WO1996027383A1/fr not_active Ceased
- 1996-02-13 AP APAP/P/1996/000872A patent/AP705A/en active
- 1996-02-13 JP JP8526645A patent/JPH10506124A/ja not_active Ceased
- 1996-02-13 EP EP96904129A patent/EP0768887B1/de not_active Expired - Lifetime
- 1996-02-13 CA CA002189474A patent/CA2189474C/fr not_active Expired - Fee Related
- 1996-02-13 AU AU48340/96A patent/AU711634B2/en not_active Ceased
- 1996-10-25 OA OA60910A patent/OA10332A/fr unknown
2001
- 2001-09-06 GR GR20010401410T patent/GR3036556T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1996027383A1 (fr)	1996-09-12
CA2189474A1 (fr)	1996-09-12
DE69613190D1 (de)	2001-07-12
EA199600087A1 (ru)	1997-09-30
AP9600872A0 (en)	1996-10-31
FR2731354B1 (fr)	1997-05-09
EP0768887B1 (de)	2001-06-06
GR3036556T3 (en)	2001-12-31
JPH10506124A (ja)	1998-06-16
DE69613190T2 (de)	2002-01-31
EA000112B1 (ru)	1998-08-27
EP0768887A1 (de)	1997-04-23
DK0768887T3 (da)	2001-09-10
ATE201825T1 (de)	2001-06-15
CA2189474C (fr)	2003-07-29
AU4834096A (en)	1996-09-23
ES2171653T3 (es)	2002-09-16
FR2731354A1 (fr)	1996-09-13
PT768887E (pt)	2001-11-30
AU711634B2 (en)	1999-10-21
AP705A (en)	1998-12-04

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