OA10958A - Trovafloxacin mesylate tablet - Google Patents

Trovafloxacin mesylate tablet Download PDF

Info

Publication number: OA10958A
Authority: OA; OAPI
Prior art keywords: composition; weight; cellulose; tablet; trovafloxacin
Prior art date: 1998-01-21

Application number

OA9900009A

Other languages

English (en)

Inventor

Alton Dale Johnson

Christopher Mickael Sinko

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-21

Filing date

1999-01-15

Publication date

2001-10-31

1999-01-15 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2001-10-31 Publication of OA10958A publication Critical patent/OA10958A/en

Links

229960005021 trovafloxacin mesylate Drugs 0.000 title claims abstract description 28
DYNZICQDCVYXFW-AHZSKCOESA-N trovafloxacin mesylate Chemical compound CS(O)(=O)=O.C([C@H]1[C@@H]([C@H]1C1)N)N1C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=NC=1N2C1=CC=C(F)C=C1F DYNZICQDCVYXFW-AHZSKCOESA-N 0.000 title claims abstract description 28
239000000203 mixture Substances 0.000 claims abstract description 55
229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 16
235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 16
239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 16
229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 16
239000000314 lubricant Substances 0.000 claims abstract description 12
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 17
229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 12
239000007888 film coating Substances 0.000 claims description 12
238000009501 film coating Methods 0.000 claims description 12
235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 12
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235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims description 10
239000007884 disintegrant Substances 0.000 claims description 8
235000010980 cellulose Nutrition 0.000 claims description 7
229920002678 cellulose Polymers 0.000 claims description 7
239000001913 cellulose Substances 0.000 claims description 7
AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims description 6
239000011248 coating agent Substances 0.000 claims description 4
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SGPGESCZOCHFCL-UHFFFAOYSA-N Tilisolol hydrochloride Chemical compound [Cl-].C1=CC=C2C(=O)N(C)C=C(OCC(O)C[NH2+]C(C)(C)C)C2=C1 SGPGESCZOCHFCL-UHFFFAOYSA-N 0.000 claims 5
238000004090 dissolution Methods 0.000 abstract description 22
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229960000497 trovafloxacin Drugs 0.000 description 16
WVPSKSLAZQPAKQ-CDMJZVDBSA-N trovafloxacin Chemical compound C([C@H]1[C@@H]([C@H]1C1)N)N1C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=NC=1N2C1=CC=C(F)C=C1F WVPSKSLAZQPAKQ-CDMJZVDBSA-N 0.000 description 16
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230000000704 physical effect Effects 0.000 description 1
239000001259 polydextrose Substances 0.000 description 1
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229940035035 polydextrose Drugs 0.000 description 1
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239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
229920000053 polysorbate 80 Polymers 0.000 description 1
229940068968 polysorbate 80 Drugs 0.000 description 1
229920002689 polyvinyl acetate Polymers 0.000 description 1
239000011118 polyvinyl acetate Substances 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000000634 powder X-ray diffraction Methods 0.000 description 1
239000000047 product Substances 0.000 description 1
HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
238000012207 quantitative assay Methods 0.000 description 1
239000003306 quinoline derived antiinfective agent Substances 0.000 description 1
238000009490 roller compaction Methods 0.000 description 1
235000002020 sage Nutrition 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
239000012898 sample dilution Substances 0.000 description 1
238000013207 serial dilution Methods 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
235000010413 sodium alginate Nutrition 0.000 description 1
239000000661 sodium alginate Substances 0.000 description 1
229940005550 sodium alginate Drugs 0.000 description 1
235000002639 sodium chloride Nutrition 0.000 description 1
235000019333 sodium laurylsulphate Nutrition 0.000 description 1
229940045902 sodium stearyl fumarate Drugs 0.000 description 1
239000007909 solid dosage form Substances 0.000 description 1
238000000527 sonication Methods 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
238000013112 stability test Methods 0.000 description 1
229910001220 stainless steel Inorganic materials 0.000 description 1
239000010935 stainless steel Substances 0.000 description 1
229940032147 starch Drugs 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000008117 stearic acid Substances 0.000 description 1
229940071138 stearyl fumarate Drugs 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
239000001789 thuja occidentalis l. leaf oil Substances 0.000 description 1
239000010678 thyme oil Substances 0.000 description 1
229960002622 triacetin Drugs 0.000 description 1
235000013976 turmeric Nutrition 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1
239000003643 water by type Substances 0.000 description 1
238000005550 wet granulation Methods 0.000 description 1
239000009637 wintergreen oil Substances 0.000 description 1
239000000811 xylitol Substances 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
229960002675 xylitol Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

OA9900009A 1998-01-21 1999-01-15 Trovafloxacin mesylate tablet OA10958A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7201398P	1998-01-21	1998-01-21

Publications (1)

Publication Number	Publication Date
OA10958A true OA10958A (en)	2001-10-31

Family

ID=22105016

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA9900009A OA10958A (en)	1998-01-21	1999-01-15	Trovafloxacin mesylate tablet

Country Status (34)

Country	Link
US (1)	US6187341B1 (id)
EP (1)	EP0930068A3 (id)
JP (1)	JPH11269072A (id)
KR (1)	KR100314977B1 (id)
CN (1)	CN1227743A (id)
AP (1)	AP1094A (id)
AR (1)	AR012780A1 (id)
AU (1)	AU758381B2 (id)
BG (1)	BG103106A (id)
BR (1)	BR9900116A (id)
CA (1)	CA2259698C (id)
CO (1)	CO4810225A1 (id)
DZ (1)	DZ2712A1 (id)
EA (1)	EA003247B1 (id)
GT (1)	GT199900004A (id)
HR (1)	HRP990023A2 (id)
HU (1)	HUP9900154A3 (id)
ID (1)	ID23735A (id)
IL (1)	IL128051A0 (id)
IS (1)	IS4947A (id)
MA (1)	MA24747A1 (id)
NO (1)	NO990243L (id)
NZ (1)	NZ333838A (id)
OA (1)	OA10958A (id)
PA (1)	PA8466701A1 (id)
PE (1)	PE20000169A1 (id)
PL (1)	PL330981A1 (id)
SG (1)	SG70666A1 (id)
SK (1)	SK4299A3 (id)
TN (1)	TNSN99007A1 (id)
TR (1)	TR199900089A3 (id)
TW (1)	TW518224B (id)
YU (1)	YU2399A (id)
ZA (1)	ZA99393B (id)

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BRPI9915208B8 (pt) *	1998-11-10	2021-07-06	Bayer Ag	preparados farmacêutico e de comprimido para a aplicação oral compreendendo moxifloxacina e seu processo de preparação.
AU1188601A (en) *	1999-09-20	2001-04-24	Alza Corporation	Process for lessening polymorphic conversion of a drug
ES2231275T3 (es) *	1999-10-08	2005-05-16	Affinium Pharmaceuticals, Inc.	Inhibidores de fab i.
FR2808441B1 (fr) *	2000-05-04	2004-06-18	Oreal	Utilisation de fibres dans une composition de soin ou de maquillage pour matifier la peau
DE10031043A1 (de) *	2000-06-26	2002-02-14	Bayer Ag	Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
JP4387804B2 (ja) *	2001-04-06	2009-12-24	アフィニアム・ファーマシューティカルズ・インコーポレイテッド	ＦａｂＩ阻害剤
EP1396263A1 (en)	2002-08-09	2004-03-10	Warner-Lambert Company	Film coating for tablets and caplets
PT1575951E (pt)	2002-12-06	2014-09-15	Debiopharm Int Sa	Compostos heterocíclicos, métodos para os preparar e sua utilização em terapia
CN100415284C (zh) *	2002-12-30	2008-09-03	毛友昌	六味木香片的制备方法
EP1608377B1 (en)	2003-03-17	2008-10-01	Affinium Pharmaceuticals, Inc.	Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
ES2297067T3 (es) *	2003-03-19	2008-05-01	The Jordanian Pharmaceutical Manufacturing Co. Ltd.	Composiciones farmaceuticas no higroscopicas que contienen acidos quinolinacarboxilicos de hidratados.
US8906413B2 (en)	2003-05-12	2014-12-09	Supernus Pharmaceuticals, Inc.	Drug formulations having reduced abuse potential
US20050019397A1 (en) *	2003-07-23	2005-01-27	Jacobs Richard L.	Cellulosic fiber containing composition
US8450307B2 (en)	2004-06-04	2013-05-28	Affinium Pharmaceuticals, Inc.	Therapeutic agents, and methods of making and using the same
AU2005295482B2 (en) *	2004-10-15	2011-03-31	Supernus Pharmaceuticals Inc.	Less abusable pharmaceutical preparations
US20090156578A1 (en) *	2005-12-05	2009-06-18	PAULS Henry	3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents
EP2054422B1 (en)	2006-07-20	2017-06-14	Debiopharm International SA	Acrylamide derivatives as fab i inhibitors
WO2008098374A1 (en) *	2007-02-16	2008-08-21	Affinium Pharmaceuticals, Inc.	Salts, prodrugs and polymorphs of fab i inhibitors
EP2861608B8 (en)	2012-06-19	2019-06-19	Debiopharm International SA	Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
DK3419628T3 (da)	2016-02-26	2021-01-11	Debiopharm Int Sa	Medikament til behandling af diabetiske fodinfektioner
ES2944535T3 (es)	2019-02-14	2023-06-22	Debiopharm Int Sa	Formulación de afabicina, método para preparar la misma
UA129222C2 (uk)	2019-06-14	2025-02-12	Дебіофарм Інтернешнл С.А.	Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою
EP4580618A2 (en) *	2022-08-30	2025-07-09	Pannex Therapeutics Inc.	Pannexin-1 modulators and methods of treating disorders in which pannexin-1 is implicated

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US5286754A (en)	1986-01-21	1994-02-15	Bayer Aktiengesellschaft	Pharmaceutical formulations of ciprofloxacin
DE3601566A1 (de) *	1986-01-21	1987-07-23	Bayer Ag	Pharmazeutische zubereitungen von ciprofloxacin
US4957554A (en)	1989-08-16	1990-09-18	Minnesota Mining And Manufacturing Company	Dimensionally-controlled ceramics
DE4120646A1 (de)	1991-06-22	1992-12-24	Bayer Ag	7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
TR199800339T1 (xx) *	1995-08-29	1998-06-22	Pfizer Inc.	Trovafloksasinin melez iyonik bi�imleri.

1999
- 1999-01-11 PA PA19998466701A patent/PA8466701A1/es unknown
- 1999-01-13 EP EP99300258A patent/EP0930068A3/en not_active Withdrawn
- 1999-01-14 AP APAP/P/1999/001443A patent/AP1094A/en active
- 1999-01-14 IL IL12805199A patent/IL128051A0/xx unknown
- 1999-01-14 SK SK42-99A patent/SK4299A3/sk unknown
- 1999-01-14 TR TR1999/00089A patent/TR199900089A3/tr unknown
- 1999-01-15 ID IDP990036D patent/ID23735A/id unknown
- 1999-01-15 OA OA9900009A patent/OA10958A/en unknown
- 1999-01-15 PE PE1999000036A patent/PE20000169A1/es not_active Application Discontinuation
- 1999-01-15 MA MA25433A patent/MA24747A1/fr unknown
- 1999-01-15 GT GT199900004A patent/GT199900004A/es unknown
- 1999-01-19 BR BR9900116-0A patent/BR9900116A/pt not_active IP Right Cessation
- 1999-01-19 IS IS4947A patent/IS4947A/is unknown
- 1999-01-19 CA CA002259698A patent/CA2259698C/en not_active Expired - Fee Related
- 1999-01-19 AR ARP990100191A patent/AR012780A1/es not_active Application Discontinuation
- 1999-01-19 JP JP11010298A patent/JPH11269072A/ja active Pending
- 1999-01-20 PL PL99330981A patent/PL330981A1/xx unknown
- 1999-01-20 NO NO990243A patent/NO990243L/no not_active Application Discontinuation
- 1999-01-20 ZA ZA9900393A patent/ZA99393B/xx unknown
- 1999-01-20 SG SG1999000117A patent/SG70666A1/en unknown
- 1999-01-20 HU HU9900154A patent/HUP9900154A3/hu unknown
- 1999-01-20 NZ NZ333838A patent/NZ333838A/xx unknown
- 1999-01-20 AU AU12173/99A patent/AU758381B2/en not_active Ceased
- 1999-01-20 YU YU2399A patent/YU2399A/sh unknown
- 1999-01-20 CN CN99101232A patent/CN1227743A/zh active Pending
- 1999-01-20 US US09/233,823 patent/US6187341B1/en not_active Expired - Fee Related
- 1999-01-20 TN TNTNSN99007A patent/TNSN99007A1/fr unknown
- 1999-01-20 KR KR1019990001589A patent/KR100314977B1/ko not_active Expired - Fee Related
- 1999-01-20 DZ DZ990013A patent/DZ2712A1/xx active
- 1999-01-21 TW TW088100897A patent/TW518224B/zh not_active IP Right Cessation
- 1999-01-21 BG BG103106A patent/BG103106A/xx unknown
- 1999-01-21 CO CO99003190A patent/CO4810225A1/es unknown
- 1999-01-21 HR HR60/072,013A patent/HRP990023A2/hr not_active Application Discontinuation
- 1999-01-21 EA EA199900046A patent/EA003247B1/ru not_active IP Right Cessation

Also Published As

Publication number	Publication date
ZA99393B (en)	2000-07-21
NO990243D0 (no)	1999-01-20
AU758381B2 (en)	2003-03-20
IS4947A (is)	1999-07-22
MA24747A1 (fr)	1999-10-01
US6187341B1 (en)	2001-02-13
ID23735A (id)	2000-05-11
CO4810225A1 (es)	1999-06-30
PA8466701A1 (es)	2000-09-29
EA199900046A3 (ru)	1999-12-29
EP0930068A2 (en)	1999-07-21
AP1094A (en)	2002-08-19
JPH11269072A (ja)	1999-10-05
NZ333838A (en)	2000-03-27
SG70666A1 (en)	2000-02-22
BR9900116A (pt)	2000-05-02
EA199900046A2 (ru)	1999-08-26
EA003247B1 (ru)	2003-02-27
KR100314977B1 (ko)	2001-11-24
AR012780A1 (es)	2000-11-08
TR199900089A2 (xx)	1999-10-21
CA2259698A1 (en)	1999-07-21
HU9900154D0 (en)	1999-03-29
TNSN99007A1 (fr)	2005-11-10
NO990243L (no)	1999-07-22
YU2399A (sh)	2002-06-19
AU1217399A (en)	1999-08-12
TW518224B (en)	2003-01-21
HUP9900154A2 (hu)	1999-09-28
EP0930068A3 (en)	1999-12-22
GT199900004A (es)	2000-07-08
CN1227743A (zh)	1999-09-08
PE20000169A1 (es)	2000-03-10
DZ2712A1 (fr)	2003-09-01
HUP9900154A3 (en)	2000-12-28
HRP990023A2 (en)	1999-08-31
SK4299A3 (en)	2000-06-12
KR19990068014A (ko)	1999-08-25
TR199900089A3 (tr)	1999-10-21
PL330981A1 (en)	1999-08-02
AP9901443A0 (en)	1999-03-31
IL128051A0 (en)	1999-11-30
CA2259698C (en)	2003-04-15
BG103106A (en)	1999-08-31

Publication	Publication Date	Title
CA2259698C (en)	2003-04-15	Trovafloxacin mesylate tablet
JP4694298B2 (ja)	2011-06-08	マトリックス制御放出デバイス
US9642806B2 (en)	2017-05-09	Antifungal compositions with improved bioavailability
US12138255B2 (en)	2024-11-12	Pharmaceutical compositions of cabozantinib
HU227397B1 (en)	2011-05-30	Pharmaceutical formulations containing darifenacin
HU222252B1 (hu)	2003-05-28	Eljárás dihidropiridin-típusú Ca-antagonistát tartalmazó nyújtott hatóanyag-leadású gyógyszerkészítmények előállítására
HU225152B1 (en)	2006-07-28	Pharmaceutical compositions containing dibenzo [b,f][1,4] thiazepine derivative
IL154731A (en)	2008-11-26	Pharmacological preparation in the form of a hydrophilic gel creates a matrix for delayed release and a method for its preparation
CN112168796B (zh)	2022-10-25	双相缓释系统控制释放的药物缓释制剂及其制备方法
MXPA01009934A (es)	2002-06-21	Sistema de recubrimiento.
EP4445899A1 (en)	2024-10-16	Sustained release dosage forms comprising complexes of low solutibility compounds, and methods for their preparation
HK1019558A (en)	2000-02-18	Trovafloxacin mesylate tablet
CZ9399A3 (cs)	2000-06-14	Tableta obsahující methansulfonát trovafloxacinu
JP2009538905A (ja)	2009-11-12	感湿性薬物を含んで成る安定性製剤及びその製造方法
KR100561785B1 (ko)	2006-03-16	염산 세페타메트 피복실을 포함하는 경구 투여용 속붕해성정제의 조성물 및 이의 제조방법
TW202435886A (zh)	2024-09-16	米爾維仙(milvexian)醫藥組合物
KR100446153B1 (ko)	2004-08-30	가용화된 이부프로펜 함유 제제의 조성물 및 그의 제조방법
WO2003007968A1 (en)	2003-01-30	A cardiotonic composition