OA10998A - Use of benzopyranols to treat neurological disorders - Google Patents

Use of benzopyranols to treat neurological disorders Download PDF

Info

Publication number: OA10998A
Authority: OA; OAPI
Prior art keywords: pain; treatment; acetyl; dimethyl; compound
Prior art date: 1996-09-18

Application number

OA9900060A

Other languages

English (en)

Inventor

Andrew Parsons

Meryn Thompson

Neil Upton

John Morris Evans

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-18

Filing date

1999-03-18

Publication date

2003-03-04

1999-03-18 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2003-03-04 Publication of OA10998A publication Critical patent/OA10998A/en

Links

SERVTOXIOYSDQO-UHFFFAOYSA-N 2h-chromen-2-ol Chemical class C1=CC=C2C=CC(O)OC2=C1 SERVTOXIOYSDQO-UHFFFAOYSA-N 0.000 title 1
208000012902 Nervous system disease Diseases 0.000 title 1
208000025966 Neurological disease Diseases 0.000 title 1
208000002193 Pain Diseases 0.000 claims abstract description 18
238000011282 treatment Methods 0.000 claims abstract description 15
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 13
201000010099 disease Diseases 0.000 claims abstract description 10
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206010003591 Ataxia Diseases 0.000 claims abstract description 7
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208000002740 Muscle Rigidity Diseases 0.000 claims abstract description 7
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LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
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206010026749 Mania Diseases 0.000 description 1
229930195725 Mannitol Natural products 0.000 description 1
229910004679 ONO2 Inorganic materials 0.000 description 1
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
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XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
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QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)

OA9900060A 1996-09-18 1999-03-18 Use of benzopyranols to treat neurological disorders OA10998A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9619492.3A GB9619492D0 (en)	1996-09-18	1996-09-18	Novel treatment

Publications (1)

Publication Number	Publication Date
OA10998A true OA10998A (en)	2003-03-04

Family

ID=10800127

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA9900060A OA10998A (en)	1996-09-18	1999-03-18	Use of benzopyranols to treat neurological disorders

Country Status (30)

Country	Link
EP (1)	EP0939630B1 (de)
JP (1)	JP2001500520A (de)
KR (1)	KR20000036184A (de)
CN (1)	CN1230885A (de)
AP (1)	AP9901473A0 (de)
AR (1)	AR008838A1 (de)
AT (1)	ATE270102T1 (de)
AU (1)	AU730465B2 (de)
BG (1)	BG103252A (de)
BR (1)	BR9712030A (de)
CA (1)	CA2266681A1 (de)
DE (1)	DE69729735T2 (de)
DZ (1)	DZ2311A1 (de)
EA (1)	EA199900306A1 (de)
ES (1)	ES2223075T3 (de)
GB (1)	GB9619492D0 (de)
HU (1)	HUP9904638A3 (de)
ID (2)	ID23175A (de)
IL (1)	IL128786A0 (de)
MA (1)	MA24321A1 (de)
NO (1)	NO991292L (de)
NZ (1)	NZ334271A (de)
OA (1)	OA10998A (de)
PE (1)	PE109898A1 (de)
PL (1)	PL332313A1 (de)
SK (1)	SK35199A3 (de)
TR (1)	TR199900527T2 (de)
UY (1)	UY24717A1 (de)
WO (1)	WO1998011890A1 (de)
ZA (1)	ZA978359B (de)

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US7119214B2 (en) *	2004-04-13	2006-10-10	Cephalon France	Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US20110319482A1 (en) *	2008-06-05	2011-12-29	Peter Blower	Novel treatments
US20130281524A1 (en) *	2008-06-05	2013-10-24	Peter Blower	Novel treatments
PT2464645T (pt)	2009-07-27	2017-10-11	Gilead Sciences Inc	Compostos heterocíclicos fusionados como moduladores do canal de iões
AU2010325755A1 (en) *	2009-12-03	2012-06-21	Proximagen Ltd	Treatment of infectious diseases
WO2011067608A1 (en) *	2009-12-03	2011-06-09	Minster Research Ltd	Treatment of allodynia and hyperalgesia
WO2012003392A1 (en)	2010-07-02	2012-01-05	Gilead Sciences, Inc.	Fused heterocyclic compounds as ion channel modulators
AU2012253653A1 (en)	2011-05-10	2013-05-02	Gilead Sciences, Inc.	Fused heterocyclic compounds as sodium channel modulators
NO3175985T3 (de)	2011-07-01	2018-04-28
TWI622583B (zh)	2011-07-01	2018-05-01	基利科學股份有限公司	作為離子通道調節劑之稠合雜環化合物
CN106397317B (zh) *	2016-09-26	2019-03-22	天津师范大学	1,2,3,4-四氢喹啉化合物及其合成方法与应用

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GB9112721D0 (en) *	1991-06-13	1991-07-31	Smithkline Beecham Plc	Novel treatment
US5510375A (en) *	1993-11-19	1996-04-23	Warner-Lambert Company	Coumarin derivatives as protease inhibitors and antiviral agents
GB9411635D0 (en) *	1994-06-10	1994-08-03	Smithkline Beecham Plc	Novel treatment
ATE250052T1 (de) *	1994-06-10	2003-10-15	Smithkline Beecham Plc	Benzopyrane und deren verwendung als heilmittel

1996
- 1996-09-18 GB GBGB9619492.3A patent/GB9619492D0/en active Pending
1997
- 1997-09-15 NZ NZ334271A patent/NZ334271A/en unknown
- 1997-09-15 EA EA199900306A patent/EA199900306A1/ru unknown
- 1997-09-15 JP JP10514309A patent/JP2001500520A/ja not_active Ceased
- 1997-09-15 AU AU47047/97A patent/AU730465B2/en not_active Ceased
- 1997-09-15 HU HU9904638A patent/HUP9904638A3/hu unknown
- 1997-09-15 PL PL97332313A patent/PL332313A1/xx unknown
- 1997-09-15 AT AT97909300T patent/ATE270102T1/de not_active IP Right Cessation
- 1997-09-15 ID IDW990097A patent/ID23175A/id unknown
- 1997-09-15 CN CN97197979A patent/CN1230885A/zh active Pending
- 1997-09-15 EP EP97909300A patent/EP0939630B1/de not_active Expired - Lifetime
- 1997-09-15 TR TR1999/00527T patent/TR199900527T2/xx unknown
- 1997-09-15 DE DE69729735T patent/DE69729735T2/de not_active Expired - Fee Related
- 1997-09-15 WO PCT/EP1997/005168 patent/WO1998011890A1/en not_active Ceased
- 1997-09-15 AP APAP/P/1999/001473A patent/AP9901473A0/en unknown
- 1997-09-15 IL IL12878697A patent/IL128786A0/xx unknown
- 1997-09-15 SK SK351-99A patent/SK35199A3/sk unknown
- 1997-09-15 BR BR9712030A patent/BR9712030A/pt not_active IP Right Cessation
- 1997-09-15 ES ES97909300T patent/ES2223075T3/es not_active Expired - Lifetime
- 1997-09-15 KR KR1019997002238A patent/KR20000036184A/ko not_active Withdrawn
- 1997-09-15 CA CA002266681A patent/CA2266681A1/en not_active Abandoned
- 1997-09-16 AR ARP970104238A patent/AR008838A1/es not_active Application Discontinuation
- 1997-09-16 MA MA24799A patent/MA24321A1/fr unknown
- 1997-09-16 UY UY24717A patent/UY24717A1/es not_active Application Discontinuation
- 1997-09-16 ID IDP973201A patent/ID19542A/id unknown
- 1997-09-17 DZ DZ970161A patent/DZ2311A1/xx active
- 1997-09-17 ZA ZA978359A patent/ZA978359B/xx unknown
- 1997-09-18 PE PE1997000831A patent/PE109898A1/es not_active Application Discontinuation
1999
- 1999-03-15 BG BG103252A patent/BG103252A/xx unknown
- 1999-03-17 NO NO991292A patent/NO991292L/no not_active Application Discontinuation
- 1999-03-18 OA OA9900060A patent/OA10998A/en unknown

Also Published As

Publication number	Publication date
SK35199A3 (en)	2000-07-11
TR199900527T2 (xx)	1999-06-21
WO1998011890A1 (en)	1998-03-26
ZA978359B (en)	1999-03-17
CN1230885A (zh)	1999-10-06
NZ334271A (en)	2001-03-30
EP0939630A1 (de)	1999-09-08
CA2266681A1 (en)	1998-03-26
HUP9904638A3 (en)	2001-08-28
ES2223075T3 (es)	2005-02-16
AU4704797A (en)	1998-04-14
UY24717A1 (es)	2001-08-27
IL128786A0 (en)	2000-01-31
EP0939630B1 (de)	2004-06-30
AR008838A1 (es)	2000-02-23
NO991292D0 (no)	1999-03-17
DZ2311A1 (fr)	2002-12-28
NO991292L (no)	1999-03-17
HUP9904638A2 (hu)	2001-05-28
KR20000036184A (ko)	2000-06-26
PL332313A1 (en)	1999-08-30
EA199900306A1 (ru)	1999-08-26
MA24321A1 (fr)	1998-04-01
DE69729735T2 (de)	2005-07-14
AP9901473A0 (en)	1999-03-31
JP2001500520A (ja)	2001-01-16
ATE270102T1 (de)	2004-07-15
BG103252A (en)	1999-09-30
AU730465B2 (en)	2001-03-08
PE109898A1 (es)	1999-03-21
ID19542A (id)	1998-07-23
DE69729735D1 (de)	2004-08-05
BR9712030A (pt)	1999-08-24
GB9619492D0 (en)	1996-10-30
ID23175A (id)	2000-03-23

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KR0177894B1 (ko)	1999-03-20	항우울제
US5886021A (en)	1999-03-23	Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for vasodilatory treatment or prophylaxis
JPH0525167A (ja)	1993-02-02	緑内障の治療に有用な置換ベンゼン誘導体
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KR100194825B1 (ko)	1999-06-15	말초 순환 개선제
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