OA11455A - 6,9-Disubstituted 2-Ätrans-(4-aminocyclohexy)aminoÜpurines. - Google Patents

6,9-Disubstituted 2-Ätrans-(4-aminocyclohexy)aminoÜpurines. Download PDF

Info

Publication number
OA11455A
OA11455A OA1200000233A OA1200000233A OA11455A OA 11455 A OA11455 A OA 11455A OA 1200000233 A OA1200000233 A OA 1200000233A OA 1200000233 A OA1200000233 A OA 1200000233A OA 11455 A OA11455 A OA 11455A
Authority
OA
OAPI
Prior art keywords
group
integer
amino
alkyl
hydrogen
Prior art date
Application number
OA1200000233A
Other languages
English (en)
Inventor
Alan J Bitonti
David R Borcherding
Jennifer A Dumont
Munson H Randall
Norton P Peet
Patrick W K Shum
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of OA11455A publication Critical patent/OA11455A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
OA1200000233A 1998-02-26 2000-08-25 6,9-Disubstituted 2-Ätrans-(4-aminocyclohexy)aminoÜpurines. OA11455A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3097598A 1998-02-26 1998-02-26

Publications (1)

Publication Number Publication Date
OA11455A true OA11455A (en) 2003-12-05

Family

ID=21856977

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200000233A OA11455A (en) 1998-02-26 2000-08-25 6,9-Disubstituted 2-Ätrans-(4-aminocyclohexy)aminoÜpurines.

Country Status (13)

Country Link
KR (1) KR100568657B1 (id)
AR (1) AR018121A1 (id)
AT (1) ATE252583T1 (id)
DE (1) DE69912248T2 (id)
DK (1) DK1056744T3 (id)
ES (1) ES2207182T3 (id)
ID (1) ID25444A (id)
NZ (1) NZ506235A (id)
OA (1) OA11455A (id)
PT (1) PT1056744E (id)
RU (1) RU2200162C2 (id)
TW (1) TWI225060B (id)
UA (1) UA66840C2 (id)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232155A (en) * 1979-09-13 1980-11-04 Bristol-Myers Company Purine compounds
AU7296896A (en) * 1995-11-01 1997-05-22 Novartis Ag Purine derivatives and processes for their preparation
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques

Also Published As

Publication number Publication date
NZ506235A (en) 2003-02-28
ES2207182T3 (es) 2004-05-16
PT1056744E (pt) 2004-03-31
TWI225060B (en) 2004-12-11
AR018121A1 (es) 2001-10-31
ID25444A (id) 2000-10-05
DE69912248T2 (de) 2004-04-22
DE69912248D1 (de) 2003-11-27
HK1030949A1 (en) 2001-05-25
ATE252583T1 (de) 2003-11-15
UA66840C2 (uk) 2004-06-15
KR100568657B1 (ko) 2006-04-07
DK1056744T3 (da) 2004-02-23
KR20010041318A (ko) 2001-05-15
RU2200162C2 (ru) 2003-03-10

Similar Documents

Publication Publication Date Title
AU747151B2 (en) 6,9-disubstituted 2-(trans-(4-aminocyclohexyl) amino) purines
US6413974B1 (en) 6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
AU748178B2 (en) 6,9-disubstituted 2-(trans-(4- aminocyclohexyl) amino)purines
CZ200376A3 (cs) Nové deriváty pyrimidinu, způsob jejich přípravy a farmaceutická kompozice, která je obsahuje
AU2002239388B2 (en) Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
US6642231B2 (en) 6,9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
OA11455A (en) 6,9-Disubstituted 2-Ätrans-(4-aminocyclohexy)aminoÜpurines.
US20030069259A1 (en) Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
CZ20003104A3 (cs) 6,9-Disubstituované 2-[trans-(4- aminocyklohexyl)amino]-puriny, farmaceutické prostředky obsahující tyto sloučeniny a použití
MXPA00008377A (en) 6,9-disubstituted 2-[trans-(4- aminocyclohexyl) amino]purines
HK1030949B (en) 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino]purines
HK1030948B (en) 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
MXPA00008376A (en) 6,9-disubstituted 2-[trans-(4- aminocyclohexyl) amino]purines
ZA200303299B (en) Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents.
KR20070017938A (ko) Ｒｔｋ 억제제로서의 6-치환된 아닐리노 퓨린