ATE252583T1 - 6,9-disubstituierte 2-(trans-(4- aminocyclohexyl)amino) purine - Google Patents

6,9-disubstituierte 2-(trans-(4- aminocyclohexyl)amino) purine

Info

Publication number
ATE252583T1
ATE252583T1 AT99908220T AT99908220T ATE252583T1 AT E252583 T1 ATE252583 T1 AT E252583T1 AT 99908220 T AT99908220 T AT 99908220T AT 99908220 T AT99908220 T AT 99908220T AT E252583 T1 ATE252583 T1 AT E252583T1
Authority
AT
Austria
Prior art keywords
aminocyclohexyl
purines
disubstituted
trans
amino
Prior art date
Application number
AT99908220T
Other languages
English (en)
Inventor
Jennifer Ann Dumont
Alan Joseph Bitonti
David Roger Borcherding
Norton Paul Peet
Harry Randall Munson
Patrick Wai-Kwok Shum
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Priority claimed from PCT/US1999/003450 external-priority patent/WO1999043675A1/en
Application granted granted Critical
Publication of ATE252583T1 publication Critical patent/ATE252583T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99908220T 1998-02-26 1999-02-18 6,9-disubstituierte 2-(trans-(4- aminocyclohexyl)amino) purine ATE252583T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3097598A 1998-02-26 1998-02-26
PCT/US1999/003450 WO1999043675A1 (en) 1998-02-26 1999-02-18 6,9-disubstituted 2-[trans-(4- aminocyclohexyl) amino]purines

Publications (1)

Publication Number Publication Date
ATE252583T1 true ATE252583T1 (de) 2003-11-15

Family

ID=21856977

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99908220T ATE252583T1 (de) 1998-02-26 1999-02-18 6,9-disubstituierte 2-(trans-(4- aminocyclohexyl)amino) purine

Country Status (13)

Country Link
KR (1) KR100568657B1 (de)
AR (1) AR018121A1 (de)
AT (1) ATE252583T1 (de)
DE (1) DE69912248T2 (de)
DK (1) DK1056744T3 (de)
ES (1) ES2207182T3 (de)
ID (1) ID25444A (de)
NZ (1) NZ506235A (de)
OA (1) OA11455A (de)
PT (1) PT1056744E (de)
RU (1) RU2200162C2 (de)
TW (1) TWI225060B (de)
UA (1) UA66840C2 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232155A (en) * 1979-09-13 1980-11-04 Bristol-Myers Company Purine compounds
PT874846E (pt) * 1995-11-01 2003-08-29 Novartis Ag Derivados de purina e processos para a sua preparacao
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques

Also Published As

Publication number Publication date
UA66840C2 (uk) 2004-06-15
ES2207182T3 (es) 2004-05-16
KR100568657B1 (ko) 2006-04-07
DE69912248T2 (de) 2004-04-22
OA11455A (en) 2003-12-05
KR20010041318A (ko) 2001-05-15
DE69912248D1 (de) 2003-11-27
PT1056744E (pt) 2004-03-31
RU2200162C2 (ru) 2003-03-10
NZ506235A (en) 2003-02-28
AR018121A1 (es) 2001-10-31
DK1056744T3 (da) 2004-02-23
TWI225060B (en) 2004-12-11
HK1030949A1 (en) 2001-05-25
ID25444A (id) 2000-10-05

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