OA12078A - Method for administering a phosphodiesterase 4 inhibitor. - Google Patents

Method for administering a phosphodiesterase 4 inhibitor. Download PDF

Info

Publication number: OA12078A
Authority: OA; OAPI
Prior art keywords: drug; administered; formulation; side effects; release
Prior art date: 1999-10-29

Application number

OA1200200126A

Other languages

English (en)

Inventor

Robert D Murdoch

Theodore J Torphy

Barry D Zussman

Original Assignee

Smithkline Beecham Corp

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-29

Filing date

2000-10-26

Publication date

2003-05-28

2000-10-26 Application filed by Smithkline Beecham Corp, Smithkline Beecham Plc filed Critical Smithkline Beecham Corp

2003-05-28 Publication of OA12078A publication Critical patent/OA12078A/en

Links

238000000034 method Methods 0.000 title claims abstract description 26
229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title abstract description 10
239000002587 phosphodiesterase IV inhibitor Substances 0.000 title abstract description 10
230000036470 plasma concentration Effects 0.000 claims abstract description 31
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WLAMNBDJUVNPJU-UHFFFAOYSA-N 2-methylbutyric acid Chemical compound CCC(C)C(O)=O WLAMNBDJUVNPJU-UHFFFAOYSA-N 0.000 claims description 4
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Inorganic Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Enzymes And Modification Thereof (AREA)

OA1200200126A 1999-10-29 2000-10-26 Method for administering a phosphodiesterase 4 inhibitor. OA12078A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US16247799P	1999-10-29	1999-10-29
US16264199P	1999-11-01	1999-11-01
US17981700P	2000-02-02	2000-02-02

Publications (1)

Publication Number	Publication Date
OA12078A true OA12078A (en)	2003-05-28

Family

ID=27388757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200200126A OA12078A (en)	1999-10-29	2000-10-26	Method for administering a phosphodiesterase 4 inhibitor.

Country Status (29)

Country	Link
US (1)	US20030212112A1 (fr)
EP (1)	EP1225884A4 (fr)
JP (1)	JP2003513038A (fr)
KR (1)	KR20020050249A (fr)
CN (1)	CN1387433A (fr)
AP (1)	AP2002002446A0 (fr)
AR (1)	AR026254A1 (fr)
AU (1)	AU772909B2 (fr)
BG (1)	BG106623A (fr)
BR (1)	BR0015039A (fr)
CA (1)	CA2389293A1 (fr)
CO (1)	CO5271676A1 (fr)
CZ (1)	CZ20021443A3 (fr)
DZ (1)	DZ3249A1 (fr)
EA (1)	EA200200502A1 (fr)
HK (1)	HK1049105A1 (fr)
HU (1)	HUP0203682A3 (fr)
IL (1)	IL148813A0 (fr)
MA (1)	MA25562A1 (fr)
MX (1)	MXPA02004220A (fr)
NO (1)	NO20021937L (fr)
NZ (1)	NZ518002A (fr)
OA (1)	OA12078A (fr)
PE (1)	PE20011004A1 (fr)
PL (1)	PL355262A1 (fr)
SK (1)	SK7292002A3 (fr)
TR (1)	TR200201150T2 (fr)
UY (1)	UY26422A1 (fr)
WO (1)	WO2001032165A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR029984A1 (es) *	2000-07-27	2003-07-23	Smithkline Beecham Corp	Metodo para reducir las exacerbaciones asociadas copd ambito
MY140561A (en)	2002-02-20	2009-12-31	Nycomed Gmbh	Dosage form containing pde 4 inhibitor as active ingredient
DE10207160A1 (de) *	2002-02-20	2003-12-18	Altana Pharma Ag	Darreichungsform enthaltend PDE 4-Hemmer als Wirkstoff
TR201815573T4 (tr) *	2002-05-28	2018-11-21	Astrazeneca Ab	Topikal olarak uygulanabilir farmasötik preparasyon.
US6822114B1 (en)	2002-10-08	2004-11-23	Albemarle Corporation	Process for production of fluoroalkoxy-substituted benzamides and their intermediates
DK1606261T3 (da)	2003-03-10	2010-01-18	Nycomed Gmbh	Hidtil ukendt fremgangsmåde til fremstilling af roflumilast
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2000
- 2000-10-26 AP APAP/P/2002/002446A patent/AP2002002446A0/en unknown
- 2000-10-26 KR KR1020027005448A patent/KR20020050249A/ko not_active Withdrawn
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- 2000-10-26 BR BR0015039-8A patent/BR0015039A/pt not_active IP Right Cessation
- 2000-10-26 CA CA002389293A patent/CA2389293A1/fr not_active Abandoned
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- 2000-10-26 JP JP2001534370A patent/JP2003513038A/ja not_active Withdrawn
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- 2000-10-26 NZ NZ518002A patent/NZ518002A/en unknown
- 2000-10-26 EP EP00975385A patent/EP1225884A4/fr not_active Withdrawn
- 2000-10-26 CZ CZ20021443A patent/CZ20021443A3/cs unknown
- 2000-10-26 CN CN00815150A patent/CN1387433A/zh active Pending
- 2000-10-26 AR ARP000105644A patent/AR026254A1/es not_active Application Discontinuation
- 2000-10-26 DZ DZ003249A patent/DZ3249A1/fr active
- 2000-10-26 TR TR2002/01150T patent/TR200201150T2/xx unknown
- 2000-10-26 WO PCT/US2000/029453 patent/WO2001032165A1/fr not_active Ceased
- 2000-10-26 SK SK729-2002A patent/SK7292002A3/sk unknown
- 2000-10-27 PE PE2000001157A patent/PE20011004A1/es not_active Application Discontinuation
- 2000-10-30 UY UY26422A patent/UY26422A1/es not_active Application Discontinuation
2002
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- 2002-04-24 NO NO20021937A patent/NO20021937L/no not_active Application Discontinuation
- 2002-04-26 MA MA26618A patent/MA25562A1/fr unknown
2003
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Also Published As

Publication number	Publication date
MXPA02004220A (es)	2002-10-17
UY26422A1 (es)	2001-07-31
AR026254A1 (es)	2003-02-05
MA25562A1 (fr)	2002-10-01
JP2003513038A (ja)	2003-04-08
HUP0203682A2 (hu)	2003-04-28
EA200200502A1 (ru)	2002-10-31
US20030212112A1 (en)	2003-11-13
IL148813A0 (en)	2002-09-12
HUP0203682A3 (en)	2003-10-28
TR200201150T2 (tr)	2002-09-23
WO2001032165A1 (fr)	2001-05-10
PL355262A1 (en)	2004-04-05
DZ3249A1 (fr)	2001-05-10
NO20021937L (no)	2002-05-30
PE20011004A1 (es)	2001-09-28
AU772909B2 (en)	2004-05-13
CO5271676A1 (es)	2003-04-30
KR20020050249A (ko)	2002-06-26
EP1225884A1 (fr)	2002-07-31
CN1387433A (zh)	2002-12-25
AU1344501A (en)	2001-05-14
BG106623A (bg)	2003-02-28
BR0015039A (pt)	2002-06-25
CZ20021443A3 (cs)	2003-01-15
EP1225884A4 (fr)	2005-06-15
NZ518002A (en)	2004-01-30
NO20021937D0 (no)	2002-04-24
SK7292002A3 (en)	2002-12-03
AP2002002446A0 (en)	2002-03-31
CA2389293A1 (fr)	2001-05-10
HK1049105A1 (zh)	2003-05-02

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